1.1 Childhood obesity definition and classification Childhood obesity is a complex, multifactorial, ongoing medical condition characterized by an excessive accumulation of body fat that negatively impacts health general and increase the risk of numerous physical, psychological and metabolic impacts over the lifespan [1]. Its fast-rising incidence and relationship with early onset of non-communicable diseases has made it one of the most urgent public health issues worldwide. Unlike adults, childhood obesity cannot be defined using fixed Body Mass Index (BMI) cut-off values, because body composition, including fat mass and lean body mass, changes constantly with growth and varies according to age and sex [2,3]. Therefore, BMI in children is assessed in relation to age and sex specific reference standards, rather than as an absolute BMI score. The Body Mass Index (BMI) is the weight in kilograms divided by the square of height in meters (kg/m²) and remains the most widely accepted and practical screening measurement to assess overweight and obesity in children [2,4]. Although BMI is not a direct measure of body fatness, it has a strong association with adiposity at the population level and is affordable, reliable, and convenient to implement in clinical practice and epidemiological research [2, 6]. For children 2 years of age and older, BMI is expressed as a percentile for age and sex based on standardized growth charts. According to the Centers for Disease Control and Prevention (CDC) and the American Academy of Pediatrics (AAP), BMI-for-age percentiles are used to classify weight status into underweight, healthy weight, overweight, and three classes of obesity. This classification facilitates early detection of excessive weight gain, enables timely implementation of preventive and therapeutic interventions, and supports consistent monitoring of growth and obesity trends in both clinical practice and public health research (2,3,5) Weight Status BMI- for-Age Percentile Underweight < 5th percentile Healthy weight 5th to < 85th percentile Overweight 85th to < 95th percentile Class 1 Obesity ≥ 95th percentile to <120% of the 95th percentile Class 2 Obesity ≥ 120% to < 140% of the 95th percentile Class 3Obesity ≥ 140% of the 95th percentiles Table 1. CDC Classification for childhood obesity Previous terminology such as extreme or morbid obesity has been replaced by the current classification of obesity into Class 1, Class 2 and Class 3. This new nomenclature reflects a person-first, non-stigmatizing language and provides a clinically meaningful assessment of disease severity and to guide appropriate care methods [3]. BMI is not usually utilized in children under 2 years of age. The World Health Organization (WHO) suggests using weight-for-length growth norms alternatively to assess obesity since no globally agreed definition for obesity based on BMI has been established for this age group [2,3]. BMI is still the standard screening tool for childhood obesity; however, it is considered an indirect marker of adiposity, not a direct measurement of body fat. Recent evidences underscore the need to define obesity as excessive body fat accumulation, not just increased body weight [6]. In 2025 an international global commission recommended a broader framework for diagnosis, in which BMI should be interpreted with at least one other anthropometric measure (e.g., waist circumference) and evidence of obesity-related organ dysfunction or functional impairment. The committee also established the term preclinical obesity, which are children with excess adiposity but without detectable organ impairment, underlining the need for early identification and appropriate management [6]. For this thesis chapter can you give the accurate and precise bibliography with citations
childhood obesity definition classification BMI percentile
childhood obesity BMI body composition age sex reference standards
CDC AAP childhood obesity BMI-for-age percentile classification 2022 2023 reference
Hampl Hassink Skinner clinical practice guideline evaluation treatment children adolescents obesity
childhood obesity 2025 commission lancet framework diagnosis preclinical adiposity organ dysfunction
childhood obesity BMI public health multifactorial non-communicable disease prevalence global
PMID: 36622115
obesity commission 2025 preclinical clinical BMI waist circumference organ dysfunction new framework
Ward Skinner Hampl childhood obesity severity classification Class 1 2 3 nomenclature person-first
Lancet 2025 global commission obesity preclinical clinical definition BMI waist circumference organ dysfunction PMID
obesity definition redefine body fat adiposity BMI waist circumference organ dysfunction 2025
PMID: 36622115
Styne Arslanian Connor childhood adolescent obesity epidemiology evaluation treatment Endocrine Society guideline
WHO childhood obesity global public health non-communicable disease 2022 2023 report reference citation
PMID: 37580053
PMID: 28359099
This is the standard WHO citation for the definition of childhood obesity as a complex, multifactorial condition and its status as a major public health challenge linked to non-communicable diseases.
This is the 2023 AAP Clinical Practice Guideline - the primary authoritative source for BMI-for-age percentile classification, the use of CDC growth charts, the age/sex-specific reference standards, BMI as the accepted screening tool, and recommendations for children 2-18 years. PMID: 36622115.
Cited for age/sex-specific body composition changes, classification terminology (Class 1, 2, 3 replacing "morbid/extreme obesity"), and person-first non-stigmatizing language. PMID: 28359099.
The CDC's official BMI-for-age percentile classification table (underweight, healthy weight, overweight, Class 1/2/3 obesity), and the recommendation that BMI remains the most widely accepted and practical screening measurement in children aged 2 years and older.
Cited alongside [2] for the practical implementation of CDC/AAP BMI-for-age percentile categories in clinical practice and public health research. You may alternatively cite:Ogden, C. L., Freedman, D. S., & Hales, C. M. (2023). CDC extended BMI-for-age percentiles versus percent of the 95th percentile. Pediatrics, 152(3), e2023062285. https://doi.org/10.1542/peds.2023-062285 PMID: 37555434
The 2025 international Lancet Commission paper recommending BMI plus at least one additional anthropometric measure (e.g., waist circumference), defining "preclinical obesity" (excess adiposity without organ impairment), and calling for a broader diagnostic framework beyond BMI alone. This is the "international global commission" referenced in your text.
| Citation | Source | PMID / DOI |
|---|---|---|
| [1] | WHO Obesity & Overweight Fact Sheet, 2024 | who.int |
| [2] | Hampl et al. (AAP CPG), Pediatrics 2023 | PMID 36622115 |
| [3] | Styne et al. (Endocrine Society CPG), JCEM 2017 | PMID 28359099 |
| [4] | CDC – Defining Childhood Weight Status, 2022 | cdc.gov |
| [5] | CDC Extended BMI charts / Ogden et al., Pediatrics 2023 | PMID 37555434 |
| [6] | Rubino et al. (Lancet Commission), Lancet Diab Endocrinol 2025 | DOI 10.1016/S2213-8587(24)00316-4 |
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Rubino clinical obesity definition diagnostic criteria Lancet Diabetes Endocrinology 2025
PMID: 39824205