from docx import Document
from docx.shared import Pt, Inches, RGBColor, Cm
from docx.enum.text import WD_ALIGN_PARAGRAPH
from docx.enum.table import WD_TABLE_ALIGNMENT, WD_ALIGN_VERTICAL
from docx.oxml.ns import qn
from docx.oxml import OxmlElement
import copy

doc = Document()

# ── Page margins (narrow for print density) ──────────────────────────────────
section = doc.sections[0]
section.page_width  = Inches(8.27)   # A4
section.page_height = Inches(11.69)
section.left_margin   = Cm(1.5)
section.right_margin  = Cm(1.5)
section.top_margin    = Cm(1.5)
section.bottom_margin = Cm(1.5)

# ── Helper: set cell background ───────────────────────────────────────────────
def set_cell_bg(cell, hex_color):
    tc   = cell._tc
    tcPr = tc.get_or_add_tcPr()
    shd  = OxmlElement('w:shd')
    shd.set(qn('w:val'),   'clear')
    shd.set(qn('w:color'), 'auto')
    shd.set(qn('w:fill'),  hex_color)
    tcPr.append(shd)

# ── Helper: set cell borders ──────────────────────────────────────────────────
def set_cell_borders(cell, top=None, bottom=None, left=None, right=None):
    tc   = cell._tc
    tcPr = tc.get_or_add_tcPr()
    tcBorders = OxmlElement('w:tcBorders')
    for side, val in [('top', top), ('bottom', bottom), ('left', left), ('right', right)]:
        if val:
            el = OxmlElement(f'w:{side}')
            el.set(qn('w:val'),   val.get('val',   'single'))
            el.set(qn('w:sz'),    val.get('sz',    '4'))
            el.set(qn('w:space'), val.get('space', '0'))
            el.set(qn('w:color'), val.get('color', '000000'))
            tcBorders.append(el)
    tcPr.append(tcBorders)

# ── Helper: bold run ──────────────────────────────────────────────────────────
def bold_para(para, text, size=11, color=None, align=WD_ALIGN_PARAGRAPH.LEFT):
    para.clear()
    run = para.add_run(text)
    run.bold = True
    run.font.size = Pt(size)
    if color:
        run.font.color.rgb = RGBColor(*color)
    para.alignment = align

# ── Helper: normal run ────────────────────────────────────────────────────────
def normal_para(para, text, size=9, bold=False, italic=False):
    para.clear()
    run = para.add_run(text)
    run.bold   = bold
    run.italic = italic
    run.font.size = Pt(size)

# ── Color palette ─────────────────────────────────────────────────────────────
COL_HEADER_PATH  = "B71C1C"  # deep red
COL_HEADER_PHARM = "F57F17"  # amber
COL_HEADER_MICRO = "1B5E20"  # dark green
COL_ROW_PATH     = "FFEBEE"  # light red
COL_ROW_PHARM    = "FFFDE7"  # light yellow
COL_ROW_MICRO    = "E8F5E9"  # light green
COL_TITLE_BG     = "1A237E"  # navy
COL_WEEK_BG      = "37474F"  # dark slate

# ══════════════════════════════════════════════════════════════════════════════
# COVER HEADER
# ══════════════════════════════════════════════════════════════════════════════
title_tbl = doc.add_table(rows=1, cols=1)
title_tbl.alignment = WD_TABLE_ALIGNMENT.CENTER
title_cell = title_tbl.rows[0].cells[0]
set_cell_bg(title_cell, COL_TITLE_BG)
p = title_cell.paragraphs[0]
p.alignment = WD_ALIGN_PARAGRAPH.CENTER
run = p.add_run("🩺  MBBS 2ND YEAR SENDUP REVISION CHECKLIST")
run.bold = True
run.font.size = Pt(16)
run.font.color.rgb = RGBColor(255, 255, 255)

p2 = title_cell.add_paragraph()
p2.alignment = WD_ALIGN_PARAGRAPH.CENTER
r2 = p2.add_run("Pathology  •  Pharmacology  •  Microbiology  |  July 17 – August 17, 2026")
r2.font.size  = Pt(10)
r2.font.color.rgb = RGBColor(200, 220, 255)

doc.add_paragraph()  # spacer

# ── Legend ────────────────────────────────────────────────────────────────────
leg = doc.add_table(rows=1, cols=4)
leg.alignment = WD_TABLE_ALIGNMENT.CENTER
colors = [("PATH", COL_HEADER_PATH), ("PHARM", COL_HEADER_PHARM),
          ("MICRO", COL_HEADER_MICRO), ("REVISION", COL_WEEK_BG)]
for i, (label, col) in enumerate(colors):
    c = leg.rows[0].cells[i]
    set_cell_bg(c, col)
    p = c.paragraphs[0]
    p.alignment = WD_ALIGN_PARAGRAPH.CENTER
    r = p.add_run(f"  {label}  ")
    r.bold = True
    r.font.size  = Pt(9)
    r.font.color.rgb = RGBColor(255, 255, 255)

doc.add_paragraph()  # spacer

# ══════════════════════════════════════════════════════════════════════════════
# DATA — 31 days
# ══════════════════════════════════════════════════════════════════════════════
schedule = [
    # (day_num, weekday, date_str, subject_code, topic_main, topic_detail, evening_revise)
    # WEEK 1
    (1,  "Friday",    "Jul 17", "PATH",  "Acute Inflammation",
     "Vascular changes · Cellular events (margination→diapedesis) · Chemical mediators (histamine, prostaglandins, leukotrienes, cytokines)",
     "Free / Light read"),
    (2,  "Saturday",  "Jul 18", "PATH",  "Chronic + Granulomatous Inflammation",
     "Chronic features · Granuloma formation · Caseating vs non-caseating · Causes (TB, Sarcoidosis, Crohn's, Foreign body)",
     "Re-test Day 1: Acute inflammation mediators"),
    (3,  "Sunday",    "Jul 19", "PATH",  "Neoplasia",
     "Benign vs Malignant criteria · Grading vs Staging · Tumor markers (CEA, AFP, PSA, CA-125, CA-19-9) · Routes of spread",
     "Days 1-2: Inflammation summary sheets"),
    (4,  "Monday",    "Jul 20", "PATH",  "Carcinogenesis",
     "Chemical (initiation/promotion) · Viral carcinogens (HPV, EBV, HBV, HTLV) · Radiation · Oncogenes vs Tumor suppressor genes",
     "Day 2: Neoplasia comparison table"),
    (5,  "Tuesday",   "Jul 21", "MICRO", "Tuberculosis",
     "Acid-fast bacillus · Ziehl-Neelsen stain · Pathogenesis · Ghon complex/focus · Ranke complex · RIPE treatment · Lab diagnosis",
     "Day 3: Carcinogenesis mechanisms"),
    (6,  "Wednesday", "Jul 22", "PHARM", "General Pharmacology – Pharmacokinetics",
     "Routes of admin · Absorption factors · Vd · Protein binding · BBB · Placental transfer · First-pass effect",
     "Day 4: TB lab diagnosis + treatment"),
    (7,  "Thursday",  "Jul 23", "PHARM", "Pharmacodynamics + Drug Metabolism",
     "Receptor types · Agonist/antagonist · ED50/LD50 · Dose-response curves · Phase I & II metabolism · Enzyme induction vs inhibition",
     "Day 5: PK concepts self-test"),

    # WEEK 2
    (8,  "Friday",    "Jul 24", "PATH",  "Thrombosis + Embolism",
     "Virchow's triad · Types of thrombi · Fates of thrombus · Pulmonary / Fat / Air / Amniotic fluid embolism",
     "Day 6: PD + drug metabolism"),
    (9,  "Saturday",  "Jul 25", "PATH",  "Infarction + Shock",
     "Red vs White infarct (why the difference) · Shock types: Hypovolemic, Cardiogenic, Septic, Neurogenic · Stages of shock",
     "Day 7: Thrombosis self-test"),
    (10, "Sunday",    "Jul 26", "MICRO", "Staphylococcus aureus",
     "Coagulase +ve · Toxins (alpha, TSST, exfoliatin, PVL) · Diseases (SSSS, TSS, food poisoning, osteomyelitis) · MRSA · Lab diagnosis",
     "Day 8: Shock types + pathophysiology"),
    (11, "Monday",    "Jul 27", "PHARM", "Cholinergic Drugs",
     "Direct acting (ACh, carbachol, pilocarpine, bethanechol) · Indirect acting (neostigmine, physostigmine) · OP toxicity (SLUDGE) · Antidote: Atropine + Pralidoxime",
     "Day 9: Staph aureus organism card"),
    (12, "Tuesday",   "Jul 28", "PHARM", "Anticholinergic + Adrenergic Drugs",
     "Atropine uses + scopolamine · Alpha/beta agonists (adrenaline, dopamine, dobutamine, salbutamol) · Clinical uses of each",
     "Day 10: Cholinergic drug table"),
    (13, "Wednesday", "Jul 29", "PATH",  "Cell Injury + Necrosis + Apoptosis",
     "Causes of cell injury · Reversible vs irreversible changes · Types of necrosis: Coagulative, Liquefactive, Caseous, Fat, Fibrinoid, Gangrenous · Necrosis vs Apoptosis",
     "Day 11: Adrenergic drugs"),
    (14, "Thursday",  "Jul 30", "MICRO", "Salmonella typhi (Typhoid)",
     "Pathogenesis (Peyer's patches) · Widal test (TO & TH titres) · Rose spots · Complications · Wilson-Blair culture · Treatment",
     "Day 12: Necrosis types table"),

    # WEEK 3
    (15, "Friday",    "Jul 31", "PATH",  "Anemias",
     "Iron deficiency (hypochromic microcytic, lab findings, stages) · Megaloblastic (B12/folate, hypersegmented neutrophils) · Pernicious anemia",
     "Day 13: Typhoid pathogenesis"),
    (16, "Saturday",  "Aug 1",  "PHARM", "NSAIDs + Analgesics",
     "COX-1 vs COX-2 · Aspirin: irreversible, antiplatelet, analgesic, anti-inflammatory, antipyretic, toxicity · Selective COX-2 inhibitors · Paracetamol toxicity + antidote (NAC)",
     "Day 14: Anemias table self-test"),
    (17, "Sunday",    "Aug 2",  "MICRO", "HIV",
     "Structure (gp120/gp41, p24, p17) · CD4 count stages · AIDS-defining conditions · Lab: ELISA→Western blot · ART basics",
     "Day 15: NSAIDs mechanisms"),
    (18, "Monday",    "Aug 3",  "PATH",  "Wound Healing",
     "Primary vs Secondary intention · Factors affecting healing: Local (infection, blood supply, foreign body) + Systemic (nutrition, diabetes, steroids) · Keloid vs hypertrophic scar",
     "Day 16: HIV stages + diagnosis"),
    (19, "Tuesday",   "Aug 4",  "PHARM", "Antihypertensives",
     "ACE inhibitors (dry cough, angioedema) · ARBs · CCBs (amlodipine vs verapamil vs diltiazem) · Thiazide diuretics · Beta-blockers in HTN",
     "Day 17: Wound healing factors"),
    (20, "Wednesday", "Aug 5",  "MICRO", "Hepatitis B",
     "Dane particle · Markers: HBsAg, HBeAg, anti-HBc, anti-HBs · Window period · Chronicity criteria · HCC link · Vaccine (HBsAg-based)",
     "Day 18: Antihypertensives table"),

    # WEEK 4
    (21, "Thursday",  "Aug 6",  "PATH",  "Hypersensitivity Types I – IV",
     "Type I: IgE, mast cells, anaphylaxis · Type II: IgG/IgM, cytotoxic · Type III: Immune complex · Type IV: T-cell mediated, delayed, Mantoux test",
     "Day 19: HBV markers"),
    (22, "Friday",    "Aug 7",  "PHARM", "Beta-blockers + Antimicrobials",
     "Propranolol (non-selective) vs atenolol (selective) · Uses + contraindications (asthma, heart block, DM) · Penicillin: mechanism, resistance (beta-lactamase), types · Cephalosporin generations",
     "Day 20: Hypersensitivity types"),
    (23, "Saturday",  "Aug 8",  "MICRO", "Streptococcus + Immunology Basics",
     "Strep pyogenes (GABHS, ASO titre) · Rheumatic fever · Glomerulonephritis · Antibody types (IgG, IgM, IgA, IgE, IgD) · Complement: classical vs alternative",
     "Day 21: Penicillin mechanism + resistance"),
    (24, "Sunday",    "Aug 9",  "PATH",  "Leukemias + Lymphomas",
     "ALL vs AML vs CML vs CLL comparison · Philadelphia chromosome (CML) · TdT marker (ALL) · Auer rods (AML) · Reed-Sternberg cells (Hodgkin lymphoma)",
     "Day 22: Strep + immunology"),
    (25, "Monday",    "Aug 10", "PHARM", "Antiepileptics + Antihistamines",
     "Phenytoin (sodium channel, gingival hyperplasia, nystagmus, hirsutism) · Valproate (broad spectrum) · Carbamazepine · H1 vs H2 blockers + clinical uses",
     "Day 23: Leukemia table"),
    (26, "Tuesday",   "Aug 11", "MICRO", "Clostridium + Sterilization & Disinfection",
     "Tetanospasmin: inhibits glycine/GABA (spastic) · Botulinum: inhibits ACh release (flaccid) · Sterilization methods: Autoclave, Dry heat, Irradiation, Filtration, Chemical",
     "Day 24: Antiepileptics"),

    # FINAL PUSH
    (27, "Wednesday", "Aug 12", "REVISION", "PATHOLOGY MEGA-REVISION",
     "Review all PATH summary sheets · Write 3 timed essay answers (Inflammation, Neoplasia, Shock) · Complete 30 MCQs",
     "Identify your 3 weakest PATH topics"),
    (28, "Thursday",  "Aug 13", "REVISION", "PHARMACOLOGY MEGA-REVISION",
     "Review all drug tables · Write drug mechanisms from memory for top 6 classes · Complete 25 MCQs",
     "Identify your 3 weakest PHARM topics"),
    (29, "Friday",    "Aug 14", "REVISION", "MICROBIOLOGY MEGA-REVISION",
     "Review all organism cards · Write TB + Typhoid + HIV pathogenesis from memory · Complete 25 MCQs",
     "Identify your 3 weakest MICRO topics"),
    (30, "Saturday",  "Aug 15", "REVISION", "WEAK SPOTS DAY",
     "3 weakest PATH + 3 weakest PHARM + 3 weakest MICRO = 9 topics × 30 min each = 4.5 hrs focused review",
     "Light summary sheet pass"),
    (31, "Sunday",    "Aug 16", "REVISION", "LIGHT REVISION ONLY – REST DAY",
     "Read summary sheets ONCE only · No new learning · Prepare stationery · Sleep by 10 PM",
     "EXAM IS TOMORROW – You've got this!"),
]

subject_colors = {
    "PATH":     (COL_HEADER_PATH,  COL_ROW_PATH),
    "PHARM":    (COL_HEADER_PHARM, COL_ROW_PHARM),
    "MICRO":    (COL_HEADER_MICRO, COL_ROW_MICRO),
    "REVISION": (COL_WEEK_BG,      "ECEFF1"),
}

subject_labels = {
    "PATH":     "PATHOLOGY",
    "PHARM":    "PHARMACOLOGY",
    "MICRO":    "MICROBIOLOGY",
    "REVISION": "REVISION",
}

# Identify week boundaries
week_headers = {1: "WEEK 1 — July 17–23", 8: "WEEK 2 — July 24–30",
                15: "WEEK 3 — July 31–August 5", 21: "WEEK 4 — August 6–11",
                27: "FINAL PUSH — August 12–16"}

for entry in schedule:
    day_num, weekday, date_str, subj, topic_main, topic_detail, evening = entry
    hdr_col, row_col = subject_colors[subj]

    # ── Week separator ────────────────────────────────────────────────────────
    if day_num in week_headers:
        wk_tbl = doc.add_table(rows=1, cols=1)
        wk_tbl.alignment = WD_TABLE_ALIGNMENT.CENTER
        wk_cell = wk_tbl.rows[0].cells[0]
        set_cell_bg(wk_cell, COL_WEEK_BG)
        p = wk_cell.paragraphs[0]
        p.alignment = WD_ALIGN_PARAGRAPH.CENTER
        run = p.add_run(f"  ✦  {week_headers[day_num]}  ✦  ")
        run.bold = True
        run.font.size = Pt(11)
        run.font.color.rgb = RGBColor(255, 255, 255)
        doc.add_paragraph().paragraph_format.space_after = Pt(2)

    # ── Main day table: 1 row × 5 cols ───────────────────────────────────────
    # Cols: [Day badge] [Subject tag] [Topic + Details] [Checklist boxes] [Notes]
    tbl = doc.add_table(rows=3, cols=5)
    tbl.alignment = WD_TABLE_ALIGNMENT.CENTER

    # Col widths (approx, A4 narrow margins ~ 17.7 cm usable)
    widths = [Cm(1.4), Cm(2.0), Cm(9.5), Cm(2.8), Cm(2.0)]
    for row in tbl.rows:
        for i, cell in enumerate(row.cells):
            cell.width = widths[i]

    # ── Row 0: Day header ─────────────────────────────────────────────────────
    # Merge row 0 col 0 across rows 0,1,2 for the day badge
    for r in range(3):
        tbl.rows[r].cells[0].merge(tbl.rows[0].cells[0])  # vertical merge day col

    # Merge row 0 col 1 across rows 0,1,2 for subject tag
    for r in range(3):
        tbl.rows[r].cells[1].merge(tbl.rows[0].cells[1])

    # Actually do the merges properly
    day_cell = tbl.cell(0, 0)
    day_cell.merge(tbl.cell(2, 0))
    set_cell_bg(day_cell, hdr_col)
    p = day_cell.paragraphs[0]
    p.alignment = WD_ALIGN_PARAGRAPH.CENTER
    p.paragraph_format.space_before = Pt(4)
    r1 = p.add_run(f"DAY\n{day_num}")
    r1.bold = True
    r1.font.size = Pt(14)
    r1.font.color.rgb = RGBColor(255, 255, 255)
    p2 = day_cell.add_paragraph(f"{weekday[:3]}\n{date_str}")
    p2.alignment = WD_ALIGN_PARAGRAPH.CENTER
    p2.runs[0].font.size = Pt(8)
    p2.runs[0].font.color.rgb = RGBColor(230, 230, 230)

    subj_cell = tbl.cell(0, 1)
    subj_cell.merge(tbl.cell(2, 1))
    set_cell_bg(subj_cell, hdr_col)
    p = subj_cell.paragraphs[0]
    p.alignment = WD_ALIGN_PARAGRAPH.CENTER
    p.paragraph_format.space_before = Pt(8)
    r = p.add_run(subject_labels[subj])
    r.bold = True
    r.font.size = Pt(8)
    r.font.color.rgb = RGBColor(255, 255, 255)

    # ── Row 0, col 2: Main topic ──────────────────────────────────────────────
    topic_cell = tbl.cell(0, 2)
    set_cell_bg(topic_cell, row_col)
    p = topic_cell.paragraphs[0]
    p.paragraph_format.space_before = Pt(3)
    r = p.add_run("📖  " + topic_main)
    r.bold = True
    r.font.size = Pt(10)

    # ── Row 1, col 2: Detail bullets ──────────────────────────────────────────
    detail_cell = tbl.cell(1, 2)
    set_cell_bg(detail_cell, row_col)
    p = detail_cell.paragraphs[0]
    run = p.add_run(topic_detail)
    run.font.size = Pt(8)
    run.font.color.rgb = RGBColor(60, 60, 60)

    # ── Row 2, col 2: Evening revision ───────────────────────────────────────
    eve_cell = tbl.cell(2, 2)
    set_cell_bg(eve_cell, "F5F5F5")
    p = eve_cell.paragraphs[0]
    r1 = p.add_run("🌙 Evening: ")
    r1.bold = True
    r1.font.size = Pt(8)
    r1.font.color.rgb = RGBColor(80, 80, 120)
    r2 = p.add_run(evening)
    r2.font.size = Pt(8)
    r2.font.color.rgb = RGBColor(80, 80, 80)

    # ── Checklist column (col 3, rows 0-2) ───────────────────────────────────
    check_labels = ["☐  Studied", "☐  Self-tested", "☐  1-page sheet done"]
    for ri, label in enumerate(check_labels):
        chk_cell = tbl.cell(ri, 3)
        set_cell_bg(chk_cell, "FFFFFF")
        p = chk_cell.paragraphs[0]
        p.paragraph_format.space_before = Pt(3)
        r = p.add_run(label)
        r.font.size = Pt(9)

    # ── Notes column (col 4, rows 0-2) ───────────────────────────────────────
    notes_cell = tbl.cell(0, 4)
    notes_cell.merge(tbl.cell(2, 4))
    set_cell_bg(notes_cell, "FAFAFA")
    p = notes_cell.paragraphs[0]
    p.paragraph_format.space_before = Pt(4)
    r = p.add_run("Notes:")
    r.bold = True
    r.font.size = Pt(8)
    r.font.color.rgb = RGBColor(120, 120, 120)
    # add blank lines for writing
    for _ in range(4):
        ln = notes_cell.add_paragraph("_" * 14)
        ln.paragraph_format.space_before = Pt(3)
        ln.runs[0].font.size = Pt(7)
        ln.runs[0].font.color.rgb = RGBColor(180, 180, 180)

    # small space after each day block
    spacer = doc.add_paragraph()
    spacer.paragraph_format.space_after = Pt(2)
    spacer.paragraph_format.space_before = Pt(0)


# ══════════════════════════════════════════════════════════════════════════════
# MASTER TOPIC TRACKER (second page area - summary checkboxes)
# ══════════════════════════════════════════════════════════════════════════════
doc.add_page_break()

# Title
p = doc.add_paragraph()
p.alignment = WD_ALIGN_PARAGRAPH.CENTER
r = p.add_run("📋  MASTER TOPIC TRACKER")
r.bold = True
r.font.size = Pt(14)
r.font.color.rgb = RGBColor(26, 35, 126)

p2 = doc.add_paragraph()
p2.alignment = WD_ALIGN_PARAGRAPH.CENTER
r2 = p2.add_run("Tick each topic when you feel confident you can answer an exam question on it")
r2.font.size = Pt(9)
r2.font.color.rgb = RGBColor(100, 100, 100)

doc.add_paragraph()

master_topics = {
    "PATHOLOGY": [
        ("Acute Inflammation – mediators + cellular events",           "Essay"),
        ("Chronic + Granulomatous Inflammation – granuloma causes",    "Essay"),
        ("Neoplasia – benign vs malignant + tumor markers",            "Essay"),
        ("Carcinogenesis – chemical, viral, radiation",                "Essay"),
        ("Cell Injury + Necrosis types",                               "SAQ"),
        ("Apoptosis – mechanism + vs necrosis",                        "MCQ/SAQ"),
        ("Cell Adaptations – atrophy, hypertrophy, hyperplasia, metaplasia, dysplasia", "SAQ"),
        ("Thrombosis – Virchow's triad + fates",                       "Essay/SAQ"),
        ("Embolism – types + pulmonary embolism",                      "SAQ"),
        ("Infarction – red vs white",                                  "SAQ"),
        ("Shock – types + stages + pathophysiology",                   "Essay"),
        ("Edema – mechanisms + types",                                 "SAQ"),
        ("Wound Healing – primary vs secondary intention + factors",   "SAQ"),
        ("Iron Deficiency Anemia – lab findings + stages",             "Essay"),
        ("Megaloblastic Anemia – B12/folate + blood film",             "Essay"),
        ("Hemolytic Anemias – overview",                               "SAQ"),
        ("Hypersensitivity Types I–IV – examples for each",           "Essay"),
        ("Leukemia – ALL/AML/CML/CLL comparison table",               "Essay"),
        ("Lymphoma – Hodgkin vs Non-Hodgkin + Reed-Sternberg",         "SAQ"),
        ("Amyloidosis – types + staining",                             "SAQ"),
        ("Myocardial Infarction + Atherosclerosis",                    "Essay"),
        ("Rheumatic Heart Disease",                                    "Essay"),
    ],
    "PHARMACOLOGY": [
        ("Pharmacokinetics – Vd, protein binding, first-pass",         "Essay/Viva"),
        ("Pharmacodynamics – receptors, agonist/antagonist, ED50",     "Essay/Viva"),
        ("Drug Metabolism – Phase I/II, enzyme induction/inhibition",  "SAQ"),
        ("Cholinergic drugs – direct + indirect acting",               "Essay"),
        ("Organophosphate toxicity – SLUDGE + management",             "Essay"),
        ("Anticholinergic drugs – atropine uses",                      "SAQ"),
        ("Adrenergic drugs – alpha/beta agonists + uses",              "Essay"),
        ("Beta-blockers – selective vs non-selective + CI",            "SAQ"),
        ("NSAIDs – COX mechanism + aspirin all uses + toxicity",       "Essay"),
        ("Paracetamol toxicity + NAC antidote",                        "SAQ"),
        ("Antihypertensives – ACE-I, ARBs, CCBs, thiazides",          "Essay"),
        ("Penicillin – mechanism + resistance + types",                "Essay"),
        ("Aminoglycosides – mechanism + ototoxicity/nephrotoxicity",   "SAQ"),
        ("Fluoroquinolones – mechanism + uses",                        "SAQ"),
        ("Antiepileptics – phenytoin, valproate, carbamazepine",       "SAQ"),
        ("Antihistamines – H1 vs H2 + uses",                          "SAQ"),
        ("Antipsychotics – chlorpromazine, extrapyramidal effects",    "SAQ"),
        ("Cardiac glycosides – digoxin mechanism + toxicity",          "SAQ"),
        ("Diuretics – furosemide, thiazides, spironolactone",          "SAQ"),
        ("Antidepressants – SSRIs vs TCAs",                            "SAQ"),
    ],
    "MICROBIOLOGY": [
        ("Mycobacterium tuberculosis – full pathogenesis + Ghon complex", "Essay"),
        ("TB – RIPE treatment + lab diagnosis (ZN stain, culture)",    "Essay"),
        ("Staphylococcus aureus – toxins + diseases + MRSA",           "Essay"),
        ("Streptococcus pyogenes – ASO titre + rheumatic fever",       "Essay"),
        ("Salmonella typhi – Widal test + weekly progression",         "Essay"),
        ("E. coli – ETEC/EPEC/EHEC types + UTI",                      "SAQ"),
        ("HIV – structure + CD4 stages + AIDS-defining + diagnosis",   "Essay"),
        ("Hepatitis B – Dane particle + all serology markers",         "Essay"),
        ("Clostridium tetani – toxin mechanism (spastic)",             "SAQ"),
        ("Clostridium botulinum – toxin mechanism (flaccid)",          "SAQ"),
        ("Immunology – Antibody types (IgG, IgM, IgA, IgE, IgD)",    "SAQ"),
        ("Complement – classical vs alternative pathway",              "SAQ"),
        ("Sterilization – methods + temperatures + uses",              "SAQ"),
        ("Malaria – Plasmodium life cycle + blood film",               "SAQ"),
        ("Candida – features + lab diagnosis + treatment",             "SAQ"),
        ("General bacteriology – Gram stain + culture media",         "MCQ/Viva"),
        ("Klebsiella + Pseudomonas – nosocomial infection features",   "MCQ"),
        ("Syphilis (Treponema) – stages + VDRL test",                  "SAQ"),
    ],
}

for subject, topics in master_topics.items():
    hdr_col = {"PATHOLOGY": COL_HEADER_PATH, "PHARMACOLOGY": COL_HEADER_PHARM,
               "MICROBIOLOGY": COL_HEADER_MICRO}[subject]
    row_col_map = {"PATHOLOGY": COL_ROW_PATH, "PHARMACOLOGY": COL_ROW_PHARM,
                   "MICROBIOLOGY": COL_ROW_MICRO}

    # Subject header
    sh_tbl = doc.add_table(rows=1, cols=1)
    sh_cell = sh_tbl.rows[0].cells[0]
    set_cell_bg(sh_cell, hdr_col)
    p = sh_cell.paragraphs[0]
    p.paragraph_format.space_before = Pt(2)
    r = p.add_run(f"  {subject}")
    r.bold = True
    r.font.size = Pt(11)
    r.font.color.rgb = RGBColor(255, 255, 255)
    doc.add_paragraph().paragraph_format.space_after = Pt(2)

    # Topics table
    col_count = 5  # checkbox | topic | type | 1st pass | final pass
    t = doc.add_table(rows=len(topics) + 1, cols=col_count)
    t.alignment = WD_TABLE_ALIGNMENT.CENTER
    col_widths = [Cm(0.8), Cm(10.5), Cm(2.0), Cm(2.0), Cm(2.4)]

    # Header row
    headers = ["", "Topic", "Exam Type", "1st Pass ☐", "Confident ☐"]
    hrow = t.rows[0]
    for i, h in enumerate(headers):
        c = hrow.cells[i]
        c.width = col_widths[i]
        set_cell_bg(c, "EEEEEE")
        p = c.paragraphs[0]
        r = p.add_run(h)
        r.bold = True
        r.font.size = Pt(8)

    row_col = row_col_map[subject]
    for ri, (topic_name, exam_type) in enumerate(topics):
        row = t.rows[ri + 1]
        row_bg = row_col if ri % 2 == 0 else "FFFFFF"

        # Checkbox col
        c0 = row.cells[0]
        c0.width = col_widths[0]
        set_cell_bg(c0, row_bg)
        p = c0.paragraphs[0]
        p.alignment = WD_ALIGN_PARAGRAPH.CENTER
        p.add_run("☐").font.size = Pt(12)

        # Topic name
        c1 = row.cells[1]
        c1.width = col_widths[1]
        set_cell_bg(c1, row_bg)
        p = c1.paragraphs[0]
        r = p.add_run(topic_name)
        r.font.size = Pt(9)

        # Exam type
        c2 = row.cells[2]
        c2.width = col_widths[2]
        set_cell_bg(c2, row_bg)
        p = c2.paragraphs[0]
        p.alignment = WD_ALIGN_PARAGRAPH.CENTER
        r = p.add_run(exam_type)
        r.font.size = Pt(8)
        r.font.color.rgb = RGBColor(80, 80, 80)

        # 1st pass box
        c3 = row.cells[3]
        c3.width = col_widths[3]
        set_cell_bg(c3, row_bg)
        p = c3.paragraphs[0]
        p.alignment = WD_ALIGN_PARAGRAPH.CENTER
        r = p.add_run("Date: ________")
        r.font.size = Pt(8)
        r.font.color.rgb = RGBColor(150, 150, 150)

        # Confident box
        c4 = row.cells[4]
        c4.width = col_widths[4]
        set_cell_bg(c4, row_bg)
        p = c4.paragraphs[0]
        p.alignment = WD_ALIGN_PARAGRAPH.CENTER
        r = p.add_run("Date: ________")
        r.font.size = Pt(8)
        r.font.color.rgb = RGBColor(150, 150, 150)

    doc.add_paragraph().paragraph_format.space_after = Pt(4)


# ── Footer note ───────────────────────────────────────────────────────────────
doc.add_page_break()
final_p = doc.add_paragraph()
final_p.alignment = WD_ALIGN_PARAGRAPH.CENTER
r = final_p.add_run("🏁  EXAM DAY: August 17, 2026")
r.bold = True
r.font.size = Pt(16)
r.font.color.rgb = RGBColor(26, 35, 126)

p2 = doc.add_paragraph()
p2.alignment = WD_ALIGN_PARAGRAPH.CENTER
r2 = p2.add_run("You studied smart. You covered what matters. Walk in with confidence.")
r2.font.size = Pt(12)
r2.font.color.rgb = RGBColor(80, 80, 80)
r2.italic = True

doc.add_paragraph()

# Motivational tracker box
mot_tbl = doc.add_table(rows=1, cols=1)
mot_cell = mot_tbl.rows[0].cells[0]
set_cell_bg(mot_cell, "E8EAF6")
p = mot_cell.paragraphs[0]
p.alignment = WD_ALIGN_PARAGRAPH.CENTER
p.paragraph_format.space_before = Pt(6)
r = p.add_run("MY GOAL FOR THIS EXAM:")
r.bold = True
r.font.size = Pt(12)
r.font.color.rgb = RGBColor(26, 35, 126)
for i in range(3):
    lp = mot_cell.add_paragraph("_" * 80)
    lp.alignment = WD_ALIGN_PARAGRAPH.CENTER
    lp.paragraph_format.space_before = Pt(8)
    lp.runs[0].font.size = Pt(10)
    lp.runs[0].font.color.rgb = RGBColor(180, 180, 180)

doc.add_paragraph()
p3 = doc.add_paragraph()
p3.alignment = WD_ALIGN_PARAGRAPH.CENTER
r3 = p3.add_run("Remind yourself WHY you're doing this every morning before you open a book.")
r3.font.size = Pt(10)
r3.italic = True
r3.font.color.rgb = RGBColor(100, 100, 120)

# ── Save ──────────────────────────────────────────────────────────────────────
out_path = "/tmp/workspace/sendup-checklist/MBBS_Sendup_Checklist_2026.docx"
doc.save(out_path)
print(f"Saved: {out_path}")

from reportlab.lib.pagesizes import A4
from reportlab.lib import colors
from reportlab.lib.units import cm, mm
from reportlab.lib.styles import getSampleStyleSheet, ParagraphStyle
from reportlab.lib.enums import TA_CENTER, TA_LEFT, TA_RIGHT
from reportlab.platypus import (
    SimpleDocTemplate, Paragraph, Spacer, Table, TableStyle,
    PageBreak, HRFlowable, KeepTogether
)
from reportlab.platypus.flowables import Flowable
from reportlab.pdfgen import canvas
from reportlab.graphics.shapes import Drawing, Rect, String
from reportlab.lib.colors import HexColor, white, black

# ── Color Palette ─────────────────────────────────────────────────────────────
NAVY        = HexColor("#1A237E")
NAVY_LIGHT  = HexColor("#3949AB")
PATH_RED    = HexColor("#C62828")
PATH_LIGHT  = HexColor("#FFEBEE")
PATH_MED    = HexColor("#EF9A9A")
PHARM_AMBER = HexColor("#E65100")
PHARM_LIGHT = HexColor("#FFF8E1")
PHARM_MED   = HexColor("#FFCC80")
MICRO_GREEN = HexColor("#1B5E20")
MICRO_LIGHT = HexColor("#E8F5E9")
MICRO_MED   = HexColor("#A5D6A7")
REV_DARK    = HexColor("#37474F")
REV_LIGHT   = HexColor("#ECEFF1")
GRAY_LIGHT  = HexColor("#F5F5F5")
GRAY_TEXT   = HexColor("#424242")
GRAY_MID    = HexColor("#9E9E9E")
GOLD        = HexColor("#F9A825")

W, H = A4  # 595.27 x 841.89 pts

OUT = "/tmp/workspace/sendup-checklist/MBBS_Study_Schedule_2026.pdf"

# ── Page template with header/footer ─────────────────────────────────────────
def make_canvas_cb(title_text):
    def on_page(canv, doc):
        canv.saveState()
        # Top stripe
        canv.setFillColor(NAVY)
        canv.rect(0, H - 28, W, 28, fill=1, stroke=0)
        canv.setFillColor(white)
        canv.setFont("Helvetica-Bold", 10)
        canv.drawString(18, H - 18, "MBBS 2nd Year Sendups 2026  |  Pathology · Pharmacology · Microbiology")
        canv.setFont("Helvetica", 8)
        canv.drawRightString(W - 18, H - 18, f"Page {doc.page}")
        # Bottom stripe
        canv.setFillColor(NAVY)
        canv.rect(0, 0, W, 18, fill=1, stroke=0)
        canv.setFillColor(white)
        canv.setFont("Helvetica", 7)
        canv.drawCentredString(W / 2, 5, "July 17 – August 17, 2026  |  Study Smart. Revise Often. Perform Your Best.")
        canv.restoreState()
    return on_page

# ── Styles ────────────────────────────────────────────────────────────────────
styles = getSampleStyleSheet()

def S(name, **kw):
    return ParagraphStyle(name, **kw)

st_cover_title = S("cov_title", fontSize=28, textColor=white,
                   fontName="Helvetica-Bold", alignment=TA_CENTER, leading=34)
st_cover_sub   = S("cov_sub",   fontSize=13, textColor=HexColor("#B3C5FF"),
                   fontName="Helvetica", alignment=TA_CENTER, leading=18)
st_cover_dates = S("cov_dates", fontSize=11, textColor=GOLD,
                   fontName="Helvetica-Bold", alignment=TA_CENTER)

st_section_hdr = S("sec_hdr", fontSize=14, textColor=white,
                   fontName="Helvetica-Bold", alignment=TA_CENTER, leading=18)
st_week_hdr    = S("wk_hdr",  fontSize=10, textColor=white,
                   fontName="Helvetica-Bold", alignment=TA_CENTER)

st_day_num   = S("day_num", fontSize=18, textColor=white,
                 fontName="Helvetica-Bold", alignment=TA_CENTER, leading=20)
st_day_date  = S("day_dt",  fontSize=7,  textColor=HexColor("#DDDDDD"),
                 fontName="Helvetica", alignment=TA_CENTER)
st_subj_tag  = S("subj",    fontSize=8,  textColor=white,
                 fontName="Helvetica-Bold", alignment=TA_CENTER, leading=10)

st_chapter   = S("chap",   fontSize=10, textColor=GRAY_TEXT,
                 fontName="Helvetica-Bold", leading=13)
st_detail    = S("detail", fontSize=8,  textColor=HexColor("#616161"),
                 fontName="Helvetica", leading=11)
st_book_ref  = S("bref",   fontSize=7.5, textColor=HexColor("#795548"),
                 fontName="Helvetica-Oblique", leading=10)
st_video_ref = S("vref",   fontSize=7.5, textColor=HexColor("#1565C0"),
                 fontName="Helvetica-Oblique", leading=10)
st_evening   = S("eve",    fontSize=8,  textColor=HexColor("#4A148C"),
                 fontName="Helvetica", leading=10)

st_cb_label  = S("cb",     fontSize=9,  textColor=GRAY_TEXT,
                 fontName="Helvetica", leading=12)
st_body      = S("body",   fontSize=9,  textColor=GRAY_TEXT,
                 fontName="Helvetica", leading=13)
st_body_bold = S("bodyb",  fontSize=9,  textColor=GRAY_TEXT,
                 fontName="Helvetica-Bold", leading=13)
st_tip_head  = S("tiph",   fontSize=10, textColor=NAVY,
                 fontName="Helvetica-Bold", leading=14)
st_tip_body  = S("tipb",   fontSize=8.5, textColor=GRAY_TEXT,
                 fontName="Helvetica", leading=12)
st_small_cen = S("smcen",  fontSize=7.5, textColor=GRAY_MID,
                 fontName="Helvetica", alignment=TA_CENTER)

# ── Data ──────────────────────────────────────────────────────────────────────
schedule = [
    # (day, weekday_short, date_str, SUBJ, chapter_title, detail, book_ref, video_src, evening_revise)

    # PATH
    (1,  "Fri", "Jul 17", "PATH",
     "Ch 1 — Cell Injury, Death & Adaptations",
     "Causes of injury · Reversible vs irreversible changes · Types of necrosis (coagulative, liquefactive, caseous, fat, fibrinoid, gangrenous) · Apoptosis mechanism · Cell adaptations: atrophy, hypertrophy, hyperplasia, metaplasia, dysplasia",
     "Robbins Basic Pathology · Ch 1 · pp. 1–40",
     "Dr. Najeeb: Cell Injury (Parts 1 & 2)  |  Pathoma Chapter 1",
     "Free — first day, just get oriented"),

    (2,  "Sat", "Jul 18", "PATH",
     "Ch 2 — Acute Inflammation",
     "Vascular changes (vasoconstriction → vasodilation) · Cellular events: margination, rolling, adhesion, diapedesis · Chemical mediators: histamine, prostaglandins, leukotrienes, complement, cytokines (IL-1, TNF) · Outcomes of acute inflammation",
     "Robbins · Ch 2 · pp. 41–65",
     "Pathoma Ch 2 (Robbins companion)  |  Ninja Nerd: Inflammation",
     "Day 1: Re-test necrosis types — write all 6 from memory"),

    (3,  "Sun", "Jul 19", "PATH",
     "Ch 2 — Chronic & Granulomatous Inflammation",
     "Features of chronic inflammation · Chronic inflammatory cells (lymphocytes, plasma cells, macrophages) · Granuloma: epithelioid cells, Langhans giant cells · Caseating vs non-caseating granulomas · Causes: TB, Sarcoidosis, Crohn's disease, Foreign body",
     "Robbins · Ch 2 · pp. 65–82",
     "Dr. Najeeb: Granulomatous Inflammation  |  Pathoma Ch 2 cont.",
     "Day 2: Acute inflammation mediator table — recall without notes"),

    (4,  "Mon", "Jul 20", "PATH",
     "Ch 3 — Tissue Repair & Wound Healing",
     "Labile vs stable vs permanent cells · Regeneration vs repair · Primary (1°) vs Secondary (2°) intention healing · Growth factors (EGF, PDGF, TGF-β) · Local factors affecting healing · Systemic factors · Keloid vs hypertrophic scar · Complications",
     "Robbins · Ch 3 · pp. 83–110",
     "Dr. Najeeb: Repair & Regeneration  |  Pathoma Ch 3",
     "Day 3: Granuloma causes — list all 5 with distinguishing feature"),

    (5,  "Tue", "Jul 21", "PATH",
     "Ch 4 — Hemodynamic Disorders (Part 1): Edema, Thrombosis",
     "Edema mechanisms: ↑hydrostatic pressure, ↓oncotic pressure, lymphatic obstruction, Na⁺ retention · Hyperemia vs congestion · Hemostasis: primary (platelet plug) + secondary (coagulation cascade) · Thrombosis: Virchow's triad · Types of thrombi · Fate of thrombus (resolution, organization, recanalization, propagation)",
     "Robbins · Ch 4 · pp. 111–140",
     "Ninja Nerd: Hemodynamics  |  Dr. Najeeb: Thrombosis",
     "Day 4: Wound healing — list local and systemic factors"),

    (6,  "Wed", "Jul 22", "PATH",
     "Ch 4 — Hemodynamic Disorders (Part 2): Embolism, Infarction, Shock",
     "Embolism types: pulmonary (saddle embolus), fat (long bone #), air (IV lines), amniotic fluid · Infarction: red (hemorrhagic) vs white (anemic) + why the difference · Shock: hypovolemic, cardiogenic, septic (distributive), neurogenic · Stages of shock: initial → compensated → decompensated → irreversible",
     "Robbins · Ch 4 · pp. 140–160",
     "Dr. Najeeb: Shock (All Types)  |  Ninja Nerd: Shock",
     "Day 5: Thrombosis — Virchow's triad + all fates of thrombus"),

    (7,  "Thu", "Jul 23", "PATH",
     "Ch 6 — Neoplasia (Part 1): Classification & Spread",
     "Definitions: neoplasm, tumor, cancer · Benign vs malignant criteria (7 differences) · Nomenclature: suffix rules (-oma, -carcinoma, -sarcoma, -blastoma) · Grading (1–4) vs Staging (TNM) · Routes of spread: local invasion, lymphatics, hematogenous, transcoelomic · Paraneoplastic syndromes",
     "Robbins · Ch 6 · pp. 195–240",
     "Pathoma Ch 5  |  Dr. Najeeb: Neoplasia Part 1",
     "Day 6: Shock types — write all 4 with one clinical example each"),

    (8,  "Fri", "Jul 24", "PATH",
     "Ch 6 — Neoplasia (Part 2): Carcinogenesis & Tumor Markers",
     "Chemical carcinogenesis: initiation (irreversible) + promotion (reversible) · Viral carcinogens: HPV→cervical/oropharyngeal, EBV→Burkitt's/nasopharyngeal, HBV→HCC, HTLV-1→T-cell leukemia · Radiation carcinogenesis · Proto-oncogenes vs tumor suppressors (Rb, p53, BRCA) · Tumor markers: AFP, CEA, PSA, CA-125, CA-19-9, LDH, β-HCG",
     "Robbins · Ch 6 · pp. 240–280",
     "Dr. Najeeb: Carcinogenesis  |  Pathoma Ch 5 cont.",
     "Day 7: Neoplasia — benign vs malignant 7-point comparison table"),

    (9,  "Sat", "Jul 25", "PATH",
     "Ch 5 — Immune System: Hypersensitivity Types I–IV",
     "Type I (Immediate/IgE): mast cells, anaphylaxis, asthma, urticaria · Type II (Cytotoxic/IgG-IgM): transfusion reactions, Goodpasture's, Grave's · Type III (Immune complex): SLE, Serum sickness, Arthus reaction, post-strep GN · Type IV (Delayed/T-cell): Contact dermatitis, Mantoux test, graft rejection, Type 1 DM",
     "Robbins · Ch 5 · pp. 161–195",
     "Dr. Najeeb: Hypersensitivity (4 parts)  |  Ninja Nerd: Hypersensitivity",
     "Day 8: Carcinogenesis — list all viral carcinogens + cancers"),

    (10, "Sun", "Jul 26", "PATH",
     "Ch 5 — Autoimmune Diseases & Amyloidosis",
     "Autoimmunity mechanisms · SLE: anti-dsDNA, anti-Smith antibodies, butterfly rash, organs affected · RA: pannus formation, RF, anti-CCP · Sjögren's: anti-Ro/La, sicca syndrome · Amyloidosis: amyloid definition · Types: AL (primary/myeloma), AA (secondary/chronic inflammation), Aβ (Alzheimer's) · Congo red stain → apple-green birefringence",
     "Robbins · Ch 5 · pp. 195–220",
     "Dr. Najeeb: SLE  |  Dr. Najeeb: Amyloidosis",
     "Day 9: Hypersensitivity — each type: Ig involved + mechanism + example"),

    (11, "Mon", "Jul 27", "PATH",
     "Ch 11 — Hematology: Red Cell Disorders & Anemias",
     "Classification of anemia · Iron deficiency anemia: causes, stages (pre-latent→latent→overt), blood film (hypochromic microcytic), lab (↓serum iron, ↓ferritin, ↑TIBC) · Megaloblastic anemia: B12 vs folate deficiency, hypersegmented neutrophils, megaloblasts · Pernicious anemia: anti-intrinsic factor antibodies · Hemolytic anemias: intravascular vs extravascular",
     "Robbins · Ch 11 · pp. 395–440",
     "Ninja Nerd: Anemias Playlist (3 videos)  |  Dr. Najeeb: Iron Deficiency",
     "Day 10: Autoimmune diseases — SLE antibodies + organs"),

    (12, "Tue", "Jul 28", "PATH",
     "Ch 11 — Hematology: Leukemias & Lymphomas",
     "ALL: children, lymphoblasts, TdT+, responds to treatment · AML: adults, Auer rods, myeloblasts · CML: adults, Philadelphia chromosome t(9;22), BCR-ABL, basophilia · CLL: elderly, smudge cells, CD5+ · Hodgkin lymphoma: Reed-Sternberg cells (owl-eye), nodular sclerosis type most common · Non-Hodgkin: classification basics",
     "Robbins · Ch 11 · pp. 440–490",
     "Ninja Nerd: Leukemia  |  Pathoma Ch 11",
     "Day 11: Anemias — build full comparison table from memory"),

    (13, "Wed", "Jul 29", "PATH",
     "Ch 10 — Cardiovascular Pathology",
     "Atherosclerosis: risk factors, fatty streak→plaque→complicated lesion, pathogenesis · MI: zones of necrosis (coagulative), timeline of changes (0-24h→1-3d→3-7d→weeks), ECG changes, complications · RHD: Jones criteria, Aschoff bodies, Anitschkow cells, mitral stenosis as #1 complication · Infective endocarditis: Osler nodes, Roth spots, Janeway lesions",
     "Robbins · Ch 10 · pp. 350–395",
     "Dr. Najeeb: Myocardial Infarction  |  Ninja Nerd: RHD",
     "Day 12: Leukemia — ALL/AML/CML/CLL comparison from memory"),

    # PHARM
    (14, "Thu", "Jul 30", "PHARM",
     "Ch 1 — General Pharmacology: Pharmacokinetics",
     "Routes of administration + advantages/disadvantages · Absorption factors (lipid solubility, ionization, surface area) · First-pass metabolism · Volume of distribution (Vd): formula + interpretation · Plasma protein binding: significance, displacement interactions · Blood-brain barrier crossing · Placental drug transfer · Bioavailability",
     "KD Tripathi · Ch 1 · pp. 1–35",
     "Dr. Najeeb: Pharmacokinetics Parts 1 & 2  |  Ninja Nerd: PK",
     "Day 13: Cardiovascular pathology — MI timeline changes"),

    (15, "Fri", "Jul 31", "PHARM",
     "Ch 1 — General Pharmacology: Pharmacodynamics",
     "Receptors: types (ion channel, GPCR, enzyme-linked, nuclear) · Agonist vs antagonist vs partial agonist · Competitive vs non-competitive antagonism · ED50 vs LD50 · Therapeutic index · Dose-response curve · Drug interactions · Drug metabolism: Phase I (oxidation/reduction/hydrolysis - CYP450) + Phase II (conjugation) · Enzyme induction (rifampicin, phenytoin) vs inhibition (ketoconazole, cimetidine)",
     "KD Tripathi · Ch 1 · pp. 35–65",
     "Dr. Najeeb: Pharmacodynamics  |  Sketchy: Receptors",
     "Day 14: PK — Vd formula, protein binding significance, first-pass examples"),

    (16, "Sat", "Aug 1", "PHARM",
     "Ch 4 — Cholinergic & Anticholinergic Drugs",
     "Cholinergic receptors: Muscarinic (M1-M5) vs Nicotinic (Nm/Nn) · Direct acting: ACh, bethanechol (GIT/bladder), carbachol (glaucoma), pilocarpine (glaucoma) · Indirect acting (anticholinesterases): neostigmine (myasthenia gravis, reverse NDMBs), physostigmine (glaucoma, atropine OD), pyridostigmine · Organophosphate poisoning: SLUDGE/DUMBELS signs + management (atropine + pralidoxime) · Anticholinergic drugs: atropine (uses: peptic ulcer, bradycardia, preanesthetic, OPC poisoning, spasms), hyoscine, ipratropium",
     "KD Tripathi · Ch 4 · pp. 90–130",
     "Dr. Najeeb: Cholinergic Pharmacology (3 parts)",
     "Day 15: PD — draw dose-response curve + explain enzyme induction with 3 examples"),

    (17, "Sun", "Aug 2", "PHARM",
     "Ch 5 — Adrenergic Drugs & Blockers",
     "Adrenergic receptors: α1 (vasoconstriction, mydriasis), α2 (presynaptic inhibition), β1 (heart rate+contractility), β2 (bronchodilation, vasodilation) · Adrenaline: α+β, anaphylaxis (drug of choice), cardiac arrest · Noradrenaline: α1+α2+β1, vasopressor · Dopamine: dose-dependent (low=renal, mid=cardiac, high=vasopressor) · Dobutamine: β1, cardiogenic shock · Salbutamol: β2, asthma · Alpha blockers: prazosin (HTN, BPH) · Beta-blockers: propranolol (non-selective) vs atenolol/metoprolol (selective β1) + clinical uses + contraindications",
     "KD Tripathi · Ch 5 · pp. 131–175",
     "Dr. Najeeb: Adrenergic Pharmacology  |  Ninja Nerd: Adrenergics",
     "Day 16: Cholinergic drugs — organophosphate management from memory"),

    (18, "Mon", "Aug 3", "PHARM",
     "Ch 10 — Autacoids: NSAIDs & Antihistamines",
     "Arachidonic acid pathway · COX-1 (constitutive, gastric protection, platelet TXA2) vs COX-2 (inducible, inflammation, fever) · Aspirin: irreversible COX inhibitor, antiplatelet (low dose), analgesic, antipyretic, anti-inflammatory · Aspirin toxicity: tinnitus, Reye's syndrome, GI bleed · Selective COX-2 inhibitors: celecoxib · Paracetamol: mechanism, hepatotoxicity, N-acetylcysteine antidote · H1 blockers: diphenhydramine, cetirizine — uses (allergy, motion sickness, sedation) · H2 blockers: ranitidine, cimetidine — uses (PUD, GERD) · Cimetidine side effects: enzyme inhibition, anti-androgen",
     "KD Tripathi · Ch 10 · pp. 180–230",
     "Dr. Najeeb: NSAIDs  |  Sketchy: Aspirin & NSAIDs",
     "Day 17: Adrenergic drugs — when to use adrenaline vs dopamine vs dobutamine"),

    (19, "Tue", "Aug 4", "PHARM",
     "Ch 28 — Antihypertensives & Diuretics",
     "ACE inhibitors: enalapril, captopril — mechanism (↓AngII, ↑bradykinin), side effects (dry cough, angioedema), contraindications (pregnancy, bilateral RAS) · ARBs: losartan — no cough · CCBs: amlodipine (DHP, peripheral) vs verapamil/diltiazem (non-DHP, cardiac) · Thiazides: hydrochlorothiazide — mechanism, side effects (hypokalemia, hyperuricemia, hyperglycemia) · Loop diuretics: furosemide — ototoxicity · K-sparing: spironolactone (anti-androgen), triamterene, amiloride · Stepped care approach to HTN",
     "KD Tripathi · Ch 28 · pp. 540–580",
     "Ninja Nerd: Antihypertensives  |  Dr. Najeeb: Diuretics",
     "Day 18: NSAIDs — aspirin ALL mechanisms + ALL uses + toxicity"),

    (20, "Wed", "Aug 5", "PHARM",
     "Ch 27 — Antiarrhythmics & Cardiac Glycosides",
     "Vaughan Williams classification: Class I (Na⁺ channel blockers: quinidine, lignocaine), Class II (beta-blockers: propranolol), Class III (K⁺ channel blockers: amiodarone), Class IV (CCBs: verapamil) · Digoxin: mechanism (inhibits Na⁺/K⁺-ATPase → ↑intracellular Ca²⁺ → ↑contractility) · Uses: CHF, AF · Toxicity signs: nausea, vomiting, yellow-green vision, arrhythmias · Digoxin toxicity treatment: K⁺ correction, digibind · Amiodarone: multiple side effects (thyroid, lung, liver, corneal deposits, photosensitivity)",
     "KD Tripathi · Ch 27 · pp. 510–540",
     "Dr. Najeeb: Cardiac Glycosides  |  Ninja Nerd: Antiarrhythmics",
     "Day 19: Antihypertensives — ACE-I vs ARB vs CCB drug table"),

    (21, "Thu", "Aug 6", "PHARM",
     "Ch 30–31 — CNS: Sedatives, Hypnotics & Antiepileptics",
     "Benzodiazepines: diazepam, lorazepam — GABA-A potentiation, uses, tolerance, withdrawal, flumazenil antidote · Barbiturates: phenobarbitone — enzyme inducer · Antiepileptics: Phenytoin (Na⁺ channel, gingival hyperplasia, nystagmus, hirsutism, folic acid deficiency, teratogenic) · Valproate (broad spectrum, GABA ↑, teratogenic — neural tube defects) · Carbamazepine (Na⁺ channel, trigeminal neuralgia, enzyme inducer) · Ethosuximide (absence seizures only, T-type Ca²⁺ channel)",
     "KD Tripathi · Ch 30–31 · pp. 370–420",
     "Dr. Najeeb: Antiepileptics  |  Sketchy: Antiepileptic Drugs",
     "Day 20: Digoxin — mechanism + toxicity features + management"),

    (22, "Fri", "Aug 7", "PHARM",
     "Ch 32–33 — CNS: Antipsychotics & Antidepressants",
     "Typical antipsychotics: chlorpromazine, haloperidol — D2 blockade · Side effects: EPS (acute dystonia, akathisia, Parkinsonism, tardive dyskinesia), NMS, anti-cholinergic, anti-adrenergic · Atypicals: clozapine (agranulocytosis), risperidone, olanzapine (metabolic syndrome) · TCAs: amitriptyline — NE+5HT reuptake inhibition, anticholinergic SEs, cardiotoxic in OD · SSRIs: fluoxetine — serotonin syndrome, SIADH · MAOIs: phenelzine — cheese reaction (tyramine) · Lithium: mania prophylaxis, narrow TI, thyroid/renal toxicity, tremor",
     "KD Tripathi · Ch 32–33 · pp. 420–470",
     "Dr. Najeeb: Antipsychotics  |  Sketchy: Antidepressants",
     "Day 21: Antiepileptics — phenytoin side effects (write all 5)"),

    (23, "Sat", "Aug 8", "PHARM",
     "Ch 45–46 — Antimicrobials: Beta-Lactams & Aminoglycosides",
     "Penicillin: mechanism (inhibit cell wall synthesis — transpeptidase/PBP) · Resistance: beta-lactamase (penicillinase) · Types: natural (penicillin G), aminopenicillins (amoxicillin+clavulanate), antistaphylococcal (cloxacillin), antipseudomonal (piperacillin) · Cephalosporins: generations 1–4 + ceftriaxone uses · Carbapenems: meropenem · Aminoglycosides: gentamicin, streptomycin — mechanism (30S inhibition), toxicities (ototoxicity + nephrotoxicity), NOT oral bioavailability",
     "KD Tripathi · Ch 45–46 · pp. 680–730",
     "Sketchy Micro: Penicillin  |  Ninja Nerd: Antibiotics",
     "Day 22: Antipsychotic side effects — EPS types + NMS features"),

    (24, "Sun", "Aug 9", "PHARM",
     "Ch 47–49 — Fluoroquinolones, Antifungals & Antivirals",
     "Fluoroquinolones: ciprofloxacin, levofloxacin — mechanism (inhibit DNA gyrase/topoisomerase IV) · Uses: UTI, typhoid, TB (2nd line), chest infections · Side effects: tendon rupture, phototoxicity, QT prolongation, avoid in children · Antifungals: amphotericin B (ergosterol binding, nephrotoxic), fluconazole (CYP inhibitor), nystatin (topical only) · Antivirals: acyclovir (HSV, VZV — chain terminator), oseltamivir (influenza — neuraminidase inhibitor) · HIV antiretrovirals: NRTIs, NNRTIs, PIs, Integrase inhibitors — mechanism overview",
     "KD Tripathi · Ch 47–49 · pp. 730–780",
     "Dr. Najeeb: Fluoroquinolones  |  Dr. Najeeb: Antifungals",
     "Day 23: Penicillin mechanism + ALL types from memory"),

    # MICRO
    (25, "Mon", "Aug 10", "MICRO",
     "Ch 1–3 — General Bacteriology & Sterilization",
     "Bacterial morphology: cocci vs bacilli vs spirilla · Gram stain: procedure + Gram+ (purple, thick peptidoglycan) vs Gram- (pink, thin PG + outer membrane) · Special stains: ZN (acid-fast), Albert's (C. diphtheriae), India ink (Cryptococcus) · Culture media: simple, enriched (blood agar), selective (MacConkey), enrichment (selenite F) · Sterilization: autoclave (121°C/15psi/15min), dry heat (160°C/1h), radiation · Disinfection vs sterilization · Pasteurization",
     "Ananthanarayan · Ch 1–3 · pp. 1–60",
     "Dr. Najeeb: Bacteriology Introduction  |  Ninja Nerd: Microbiology Intro",
     "Day 24: Fluoroquinolones + antifungals comparison table"),

    (26, "Tue", "Aug 11", "MICRO",
     "Ch 16 — Mycobacteria: Tuberculosis & Leprosy",
     "M. tuberculosis: acid-fast bacillus, Ziehl-Neelsen stain (red bacilli on blue) · Pathogenesis: inhalation → primary complex (Ghon focus + hilar LN = Ghon complex) → Ranke complex (calcified) → secondary TB (reactivation) · Miliary TB · Lab: ZN smear, LJ medium (slow growth), tuberculin test (Mantoux) · RIPE: Rifampicin (enzyme inducer, red urine), Isoniazid (peripheral neuropathy — give pyridoxine), Pyrazinamide, Ethambutol (optic neuritis) · Leprosy: M. leprae, tuberculoid vs lepromatous, Ridley-Jopling classification",
     "Ananthanarayan · Ch 16 · pp. 330–370",
     "Dr. Najeeb: Mycobacterium tuberculosis (2 parts)",
     "Day 25: Gram stain procedure + Gram+ vs Gram- differences"),

    (27, "Wed", "Aug 12", "MICRO",
     "Ch 14–15 — Gram-Positive Cocci: Staph & Strep",
     "Staph aureus: coagulase +ve, beta-hemolysis, golden colonies on blood agar · Toxins: alpha (cell membrane), TSST-1 (TSS), exfoliatin (SSSS), PVL (necrotic lesions), enterotoxin (food poisoning) · MRSA: resistance mechanism (altered PBP2a) · Strep pyogenes (Group A): GABHS, beta-hemolysis, ASO titre, post-strep complications (rheumatic fever + glomerulonephritis) · Strep pneumoniae: alpha-hemolysis, lancet-shaped diplococci, optochin sensitive, capsule (quellung reaction) · Pneumonia, meningitis, otitis media",
     "Ananthanarayan · Ch 14–15 · pp. 270–330",
     "Ninja Nerd: Staphylococcus  |  Dr. Najeeb: Streptococcus",
     "Day 26: TB — Ghon complex vs Ranke complex + RIPE side effects"),

    (28, "Thu", "Aug 13", "MICRO",
     "Ch 27–28 — Enteric Bacteria: Salmonella, E. coli & Shigella",
     "Salmonella typhi: typhoid fever — Peyer's patches → bacteremia → rose spots · Widal test: TO (O antigen) & TH (H antigen) titres · Weekly progression: W1 (fever+headache), W2 (rose spots+hepatosplenomegaly), W3 (intestinal perforation risk), W4 (resolution) · Culture: Wilson-Blair (black colonies), blood culture (best in week 1) · Treatment: ciprofloxacin/ceftriaxone · E. coli types: ETEC (traveller's diarrhea), EPEC (infant diarrhea), EHEC/STEC O157:H7 (HUS) · E. coli: most common UTI organism · Shigella: no H2S, no gas, bacillary dysentery",
     "Ananthanarayan · Ch 27–28 · pp. 430–490",
     "Dr. Najeeb: Salmonella typhi  |  Ninja Nerd: E. coli",
     "Day 27: Staph aureus — all toxins + diseases produced"),

    (29, "Fri", "Aug 14", "MICRO",
     "Ch 57–58 — Virology: HIV & Hepatitis Viruses",
     "HIV: ssRNA retrovirus · Structure: gp120 (CD4 binding), gp41 (fusion), p24 (capsid — lab marker), p17 (matrix) · Life cycle: CD4 + CCR5/CXCR4 binding → reverse transcriptase → integration · Stages: acute (↑viral load, ↓CD4) → latent → AIDS (CD4 <200) · AIDS-defining conditions · Diagnosis: ELISA → Western blot (confirmatory) · ART: NRTIs, NNRTIs, PIs · Hepatitis: A (fecal-oral, no chronicity), B (Dane particle, HBsAg/HBeAg/anti-HBc markers, window period, 5-10% chronic, HCC) · Hepatitis C (blood-borne, 80% chronic, interferon/ribavirin/DAAs) · Hepatitis D (only with HBV) · Hepatitis E (fecal-oral, severe in pregnancy)",
     "Ananthanarayan · Ch 57–58 · pp. 620–680",
     "Ninja Nerd: HIV  |  Dr. Najeeb: Hepatitis Viruses",
     "Day 28: Typhoid — Widal test interpretation + weekly progression"),

    (30, "Sat", "Aug 15", "MICRO",
     "Ch 7–8 — Immunology: Innate, Adaptive, Antibodies & Complement",
     "Innate immunity: physical barriers, phagocytes, NK cells, complement, pattern recognition (TLRs) · Adaptive immunity: T cells (CD4 helper, CD8 cytotoxic) vs B cells · MHC I vs MHC II: which presents to which T cell · Antibody structure: FAB (antigen binding) + FC (effector) · Immunoglobulin classes: IgG (most abundant, crosses placenta), IgM (first response, pentameric), IgA (secretory, gut), IgE (allergy/parasites), IgD (B cell surface) · Complement: Classical pathway (IgG/IgM → C1q) vs Alternative (spontaneous C3) vs Lectin · MAC (membrane attack complex) · Opsonization",
     "Ananthanarayan · Ch 7–8 · pp. 90–150",
     "Dr. Najeeb: Immunology Series  |  Ninja Nerd: Complement System",
     "Day 29: HIV — structure + CD4 count at each stage + AIDS-defining conditions"),

    # FINAL
    (31, "Sun", "Aug 16", "REV",
     "FULL REVISION DAY — Summary Sheets Only",
     "Morning (2h): Read through all PATH summary sheets — no book, notes only · Afternoon (2h): Read through all PHARM drug tables — write 5 drug mechanisms from memory · Evening (1.5h): Read through all MICRO organism cards — write TB and Typhoid pathogenesis from memory · Night: STOP studying at 9 PM · Prepare your exam kit · Sleep by 10:30 PM · You have prepared well — trust the process",
     "Your own 1-page summary sheets (30 total)",
     "NO videos today — consolidation day only",
     "EXAM IS TOMORROW, August 17 — You are ready!"),
]

subj_info = {
    "PATH":  ("PATHOLOGY",       PATH_RED,    PATH_LIGHT,  PATH_MED),
    "PHARM": ("PHARMACOLOGY",    PHARM_AMBER, PHARM_LIGHT, PHARM_MED),
    "MICRO": ("MICROBIOLOGY",    MICRO_GREEN, MICRO_LIGHT, MICRO_MED),
    "REV":   ("FULL REVISION",   REV_DARK,    REV_LIGHT,   HexColor("#90A4AE")),
}

week_breaks = {
    1:  ("PHASE 1 — PATHOLOGY",     "Days 1–13  |  July 17–29",     PATH_RED),
    14: ("PHASE 2 — PHARMACOLOGY",  "Days 14–24  |  July 30–August 9",   PHARM_AMBER),
    25: ("PHASE 3 — MICROBIOLOGY",  "Days 25–30  |  August 10–15",  MICRO_GREEN),
    31: ("PHASE 4 — FINAL REVISION","Day 31  |  August 16",          REV_DARK),
}

# ─────────────────────────────────────────────────────────────────────────────
# BUILD PDF
# ─────────────────────────────────────────────────────────────────────────────
doc = SimpleDocTemplate(
    OUT,
    pagesize=A4,
    leftMargin=1.4*cm, rightMargin=1.4*cm,
    topMargin=1.6*cm, bottomMargin=1.4*cm,
    title="MBBS 2nd Year Sendup Study Schedule 2026",
    author="Orris Study Planner",
)

story = []

# ════════════════════════════════════════════════════════════════════════════
# COVER PAGE
# ════════════════════════════════════════════════════════════════════════════
story.append(Spacer(1, 1.5*cm))

# Big navy cover block
cover_data = [
    [Paragraph("🩺  MBBS 2nd Year Sendup", st_cover_title)],
    [Paragraph("Chapter-by-Chapter Study Schedule", st_cover_title)],
    [Spacer(1, 0.3*cm)],
    [Paragraph("Pathology  ·  Pharmacology  ·  Microbiology", st_cover_sub)],
    [Spacer(1, 0.3*cm)],
    [Paragraph("July 17 – August 17, 2026  |  31 Days", st_cover_dates)],
    [Spacer(1, 0.2*cm)],
    [Paragraph("6–8 hrs/day  |  Video → Book → Self-test  |  Spaced Repetition", st_cover_sub)],
]
cover_tbl = Table(cover_data, colWidths=[W - 2.8*cm])
cover_tbl.setStyle(TableStyle([
    ("BACKGROUND",  (0,0), (-1,-1), NAVY),
    ("TOPPADDING",  (0,0), (-1,-1), 8),
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    ("LEFTPADDING", (0,0), (-1,-1), 20),
    ("RIGHTPADDING",(0,0), (-1,-1), 20),
    ("ROWBACKGROUNDS",(0,0),(-1,-1), [NAVY]),
]))
story.append(cover_tbl)
story.append(Spacer(1, 0.6*cm))

# ── BOOKS vs VIDEOS QUICK GUIDE ──────────────────────────────────────────────
bv_title = Table([[Paragraph("📚  Books vs Videos — The Winning Formula", st_tip_head)]],
                 colWidths=[W - 2.8*cm])
bv_title.setStyle(TableStyle([
    ("BACKGROUND",  (0,0),(-1,-1), HexColor("#E8EAF6")),
    ("TOPPADDING",  (0,0),(-1,-1), 6),
    ("BOTTOMPADDING",(0,0),(-1,-1), 6),
    ("LEFTPADDING", (0,0),(-1,-1), 10),
]))
story.append(bv_title)

formula_data = [
    [
        Paragraph("<b>Step 1</b>", st_tip_body),
        Paragraph("🎬 Watch Video (30–45 min)", st_tip_body),
        Paragraph("Creates a mental skeleton for the chapter — new concepts feel familiar", st_tip_body),
    ],
    [
        Paragraph("<b>Step 2</b>", st_tip_body),
        Paragraph("📖 Read Book Chapter (90–120 min)", st_tip_body),
        Paragraph("Fill the skeleton with detail — facts attach to the structure you already have", st_tip_body),
    ],
    [
        Paragraph("<b>Step 3</b>", st_tip_body),
        Paragraph("✍️ Make 1-Page Summary (30 min)", st_tip_body),
        Paragraph("Forces synthesis — condense the chapter onto one page in your own words", st_tip_body),
    ],
    [
        Paragraph("<b>Step 4</b>", st_tip_body),
        Paragraph("🧠 Self-Test (30 min)", st_tip_body),
        Paragraph("Close everything. Write or speak the chapter out loud. What you stumble on = gaps", st_tip_body),
    ],
]
formula_tbl = Table(formula_data, colWidths=[1.5*cm, 5.5*cm, 10.8*cm - 2.8*cm])
# Recalculate: usable width = W - 2.8cm margins ≈ 17.7cm; cols: 1.5+5+11.2 = 17.7
formula_tbl = Table(formula_data, colWidths=[1.5*cm, 5.2*cm, 11.0*cm])
formula_tbl.setStyle(TableStyle([
    ("BACKGROUND",  (0,0),(-1,-1), HexColor("#F3F4FF")),
    ("ROWBACKGROUNDS",(0,0),(-1,-1), [HexColor("#F3F4FF"), HexColor("#FAFAFA")]),
    ("TOPPADDING",  (0,0),(-1,-1), 4),
    ("BOTTOMPADDING",(0,0),(-1,-1), 4),
    ("LEFTPADDING", (0,0),(-1,-1), 6),
    ("LINEBELOW",   (0,0),(-1,-2), 0.3, HexColor("#CCCCCC")),
]))
story.append(formula_tbl)
story.append(Spacer(1, 0.4*cm))

# ── SOURCES TABLE ─────────────────────────────────────────────────────────────
src_data = [
    [Paragraph("<b>Subject</b>", st_tip_body),
     Paragraph("<b>Primary Textbook</b>", st_tip_body),
     Paragraph("<b>Best Video Source</b>", st_tip_body),
     Paragraph("<b>Backup Videos</b>", st_tip_body)],
    [Paragraph("Pathology", st_tip_body),
     Paragraph("Robbins Basic Pathology", st_tip_body),
     Paragraph("Pathoma (Dr. Husain Sattar)", st_tip_body),
     Paragraph("Dr. Najeeb, Ninja Nerd", st_tip_body)],
    [Paragraph("Pharmacology", st_tip_body),
     Paragraph("KD Tripathi Essentials", st_tip_body),
     Paragraph("Dr. Najeeb Pharmacology", st_tip_body),
     Paragraph("Sketchy Pharm, Ninja Nerd", st_tip_body)],
    [Paragraph("Microbiology", st_tip_body),
     Paragraph("Ananthanarayan & Paniker", st_tip_body),
     Paragraph("Dr. Najeeb Microbiology", st_tip_body),
     Paragraph("Ninja Nerd, Sketchy Micro", st_tip_body)],
]
src_tbl = Table(src_data, colWidths=[3.2*cm, 4.5*cm, 5.0*cm, 5.0*cm])
src_tbl.setStyle(TableStyle([
    ("BACKGROUND",   (0,0),(-1,0),  HexColor("#1A237E")),
    ("TEXTCOLOR",    (0,0),(-1,0),  white),
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    ("ROWBACKGROUNDS",(0,1),(-1,-1),[HexColor("#FFEBEE"),HexColor("#FFFDE7"),HexColor("#E8F5E9")]),
    ("TOPPADDING",   (0,0),(-1,-1), 4),
    ("BOTTOMPADDING",(0,0),(-1,-1), 4),
    ("LEFTPADDING",  (0,0),(-1,-1), 6),
    ("GRID",         (0,0),(-1,-1), 0.3, HexColor("#CCCCCC")),
]))
story.append(src_tbl)
story.append(Spacer(1, 0.4*cm))

# ── MEMORY SYSTEM BOX ────────────────────────────────────────────────────────
mem_data = [[
    Paragraph("🧠  SPACED REPETITION RULE: After studying each chapter, mark it for review on: Day+1 (10-min self-test) → Day+3 (re-read summary) → Day+7 (past paper Q) → Day+14 (confidence check). This moves content from short-term into long-term memory.", st_tip_body)
]]
mem_tbl = Table(mem_data, colWidths=[W - 2.8*cm])
mem_tbl.setStyle(TableStyle([
    ("BACKGROUND",   (0,0),(-1,-1), HexColor("#FFF8E1")),
    ("TOPPADDING",   (0,0),(-1,-1), 8),
    ("BOTTOMPADDING",(0,0),(-1,-1), 8),
    ("LEFTPADDING",  (0,0),(-1,-1), 10),
    ("LINEABOVE",    (0,0),(-1,-1), 2, GOLD),
]))
story.append(mem_tbl)

story.append(PageBreak())

# ════════════════════════════════════════════════════════════════════════════
# DAY CARDS
# ════════════════════════════════════════════════════════════════════════════
for entry in schedule:
    day, wd, dt, subj, chapter, detail, book_ref, video, evening = entry
    label, hdr_col, bg_col, med_col = subj_info[subj]

    # ── Phase header ─────────────────────────────────────────────────────────
    if day in week_breaks:
    	ph_name, ph_dates, ph_col = week_breaks[day]
    	ph_data = [[
            Paragraph(f"◆  {ph_name}", S("ph_n", fontSize=12, textColor=white,
                      fontName="Helvetica-Bold", alignment=TA_CENTER)),
            Paragraph(ph_dates, S("ph_d", fontSize=9, textColor=HexColor("#CCCCCC"),
                      fontName="Helvetica", alignment=TA_CENTER)),
        ]]
    	ph_tbl = Table(ph_data, colWidths=[11.0*cm, 6.7*cm])
    	ph_tbl.setStyle(TableStyle([
            ("BACKGROUND",   (0,0),(-1,-1), ph_col),
            ("TOPPADDING",   (0,0),(-1,-1), 7),
            ("BOTTOMPADDING",(0,0),(-1,-1), 7),
            ("LEFTPADDING",  (0,0),(-1,-1), 10),
        ]))
    	story.append(ph_tbl)
    	story.append(Spacer(1, 0.2*cm))

    # ── Day card ─────────────────────────────────────────────────────────────
    # Layout: [Day badge | Subject tag | Chapter + details | Checkboxes | Notes]
    # Col widths: 1.4 | 2.2 | 8.8 | 2.6 | 2.7  = 17.7 cm

    # Column 1: Day badge
    col1 = [
        Paragraph(f"DAY<br/><font size='18'><b>{day}</b></font>", S("d1",
            fontSize=9, textColor=white, fontName="Helvetica-Bold",
            alignment=TA_CENTER, leading=14)),
        Paragraph(f"{wd}<br/>{dt}", S("d2",
            fontSize=7, textColor=HexColor("#DDDDDD"),
            fontName="Helvetica", alignment=TA_CENTER, leading=10)),
    ]

    # Column 2: Subject tag
    col2 = [
        Paragraph(label, S("s1",
            fontSize=7.5, textColor=white, fontName="Helvetica-Bold",
            alignment=TA_CENTER, leading=10)),
    ]

    # Column 3: Content
    col3_content = [
        Paragraph(f"📖  {chapter}", st_chapter),
        Spacer(1, 2),
        Paragraph(detail, st_detail),
        Spacer(1, 3),
        Paragraph(f"📗 <b>Book:</b>  {book_ref}", st_book_ref),
        Paragraph(f"🎬 <b>Video:</b>  {video}", st_video_ref),
        Spacer(1, 2),
        Paragraph(f"🌙 <b>Evening:</b>  {evening}", st_evening),
    ]

    # Column 4: Checkboxes
    col4_content = [
        Paragraph("☐  Watched video",   st_cb_label),
        Spacer(1, 3),
        Paragraph("☐  Read chapter",     st_cb_label),
        Spacer(1, 3),
        Paragraph("☐  1-page summary",   st_cb_label),
        Spacer(1, 3),
        Paragraph("☐  Self-tested",      st_cb_label),
        Spacer(1, 3),
        Paragraph("☐  Evening revision", st_cb_label),
    ]

    # Column 5: Notes lines
    col5_content = [
        Paragraph("<b>Notes:</b>", S("nl", fontSize=7.5, textColor=GRAY_MID,
                  fontName="Helvetica-Bold")),
        Spacer(1, 3),
    ] + [Paragraph("_" * 20, S("nll", fontSize=6.5, textColor=HexColor("#CCCCCC"),
                  fontName="Helvetica")) for _ in range(5)]

    inner_data = [[col1, col2, col3_content, col4_content, col5_content]]
    inner_tbl = Table(inner_data,
                      colWidths=[1.4*cm, 2.2*cm, 8.8*cm, 2.8*cm, 2.5*cm],
                      rowHeights=None)
    inner_tbl.setStyle(TableStyle([
        ("BACKGROUND",    (0,0), (0,0),  hdr_col),
        ("BACKGROUND",    (1,0), (1,0),  hdr_col),
        ("BACKGROUND",    (2,0), (2,0),  bg_col),
        ("BACKGROUND",    (3,0), (3,0),  HexColor("#FFFFFF")),
        ("BACKGROUND",    (4,0), (4,0),  GRAY_LIGHT),
        ("VALIGN",        (0,0), (-1,-1), "TOP"),
        ("TOPPADDING",    (0,0), (-1,-1), 5),
        ("BOTTOMPADDING", (0,0), (-1,-1), 5),
        ("LEFTPADDING",   (0,0), (-1,-1), 5),
        ("RIGHTPADDING",  (0,0), (-1,-1), 5),
        ("BOX",           (0,0), (-1,-1), 0.5, HexColor("#CCCCCC")),
        ("LINEAFTER",     (0,0), (0,0),  0.5, HexColor("#AAAAAA")),
        ("LINEAFTER",     (1,0), (1,0),  0.5, HexColor("#AAAAAA")),
        ("LINEAFTER",     (2,0), (2,0),  0.5, HexColor("#DDDDDD")),
        ("LINEAFTER",     (3,0), (3,0),  0.5, HexColor("#DDDDDD")),
    ]))

    story.append(KeepTogether(inner_tbl))
    story.append(Spacer(1, 0.18*cm))


# ════════════════════════════════════════════════════════════════════════════
# MASTER CHECKLIST PAGE
# ════════════════════════════════════════════════════════════════════════════
story.append(PageBreak())

story.append(Table([[Paragraph("📋  MASTER CHAPTER CHECKLIST", S("mch",
    fontSize=14, textColor=white, fontName="Helvetica-Bold", alignment=TA_CENTER))]],
    colWidths=[W-2.8*cm]))
story.append(Spacer(1, 0.3*cm))

master = {
    "PATHOLOGY": [
        "Ch 1 — Cell Injury, Necrosis, Apoptosis, Adaptations",
        "Ch 2 — Acute Inflammation (mediators, cellular events)",
        "Ch 2 — Chronic + Granulomatous Inflammation",
        "Ch 3 — Tissue Repair & Wound Healing",
        "Ch 4 — Edema, Thrombosis (Virchow's triad, fates)",
        "Ch 4 — Embolism, Infarction, Shock (types + stages)",
        "Ch 6 — Neoplasia: Benign vs Malignant, Staging, Spread",
        "Ch 6 — Carcinogenesis, Oncogenes, Tumor Markers",
        "Ch 5 — Hypersensitivity Types I–IV",
        "Ch 5 — Autoimmune Diseases + Amyloidosis",
        "Ch 11 — Anemias (Iron def, Megaloblastic, Hemolytic)",
        "Ch 11 — Leukemias + Lymphomas (Philadelphia, RS cells)",
        "Ch 10 — Atherosclerosis, MI, RHD, Infective Endocarditis",
    ],
    "PHARMACOLOGY": [
        "Ch 1 — Pharmacokinetics (Vd, protein binding, first-pass)",
        "Ch 1 — Pharmacodynamics + Drug Metabolism (Phase I/II)",
        "Ch 4 — Cholinergic Drugs + OP Poisoning Management",
        "Ch 5 — Adrenergic Drugs + Beta/Alpha Blockers",
        "Ch 10 — NSAIDs (Aspirin all uses), Paracetamol toxicity",
        "Ch 10 — Antihistamines (H1 vs H2 blockers)",
        "Ch 28 — Antihypertensives (ACE-I, ARB, CCB, thiazide)",
        "Ch 28 — Diuretics (furosemide, spironolactone)",
        "Ch 27 — Antiarrhythmics + Digoxin mechanism + toxicity",
        "Ch 30-31 — Sedatives, Antiepileptics (phenytoin, valproate)",
        "Ch 32-33 — Antipsychotics + Antidepressants + Lithium",
        "Ch 45-46 — Penicillins, Cephalosporins, Aminoglycosides",
        "Ch 47-49 — Fluoroquinolones, Antifungals, Antivirals",
    ],
    "MICROBIOLOGY": [
        "Ch 1-3 — General Bacteriology + Staining + Sterilization",
        "Ch 16 — M. tuberculosis (Ghon complex, ZN stain, RIPE)",
        "Ch 16 — Leprosy (M. leprae, tuberculoid vs lepromatous)",
        "Ch 14 — Staphylococcus aureus (toxins, MRSA, diseases)",
        "Ch 15 — Streptococcus (GABHS, ASO titre, RHD, GN)",
        "Ch 27 — Salmonella typhi (Widal test, weekly stages)",
        "Ch 28 — E. coli (ETEC/EPEC/EHEC/UTI) + Shigella",
        "Ch 57 — HIV (structure, CD4 stages, AIDS, diagnosis)",
        "Ch 58 — Hepatitis viruses (A/B/C/D/E comparison)",
        "Ch 7-8 — Immunology (Ig types, complement pathways)",
        "Ch 8 — Clostridium (tetani vs botulinum — mechanism diff)",
        "Ch 8 — Malaria (Plasmodium life cycle + blood film)",
        "Ch 8 — Mycology: Candida + Aspergillus basics",
    ],
}

for subj_name, chapters in master.items():
    hdr_col = {"PATHOLOGY": PATH_RED, "PHARMACOLOGY": PHARM_AMBER,
               "MICROBIOLOGY": MICRO_GREEN}[subj_name]
    bg_col  = {"PATHOLOGY": PATH_LIGHT, "PHARMACOLOGY": PHARM_LIGHT,
               "MICROBIOLOGY": MICRO_LIGHT}[subj_name]

    sh = Table([[Paragraph(f"  {subj_name}", S("sh", fontSize=11, textColor=white,
                fontName="Helvetica-Bold"))]],
               colWidths=[W-2.8*cm])
    sh.setStyle(TableStyle([
        ("BACKGROUND",   (0,0),(-1,-1), hdr_col),
        ("TOPPADDING",   (0,0),(-1,-1), 5),
        ("BOTTOMPADDING",(0,0),(-1,-1), 5),
        ("LEFTPADDING",  (0,0),(-1,-1), 8),
    ]))
    story.append(sh)

    rows = [[
        Paragraph("<b>#</b>", S("mhh", fontSize=8, textColor=GRAY_MID, fontName="Helvetica-Bold")),
        Paragraph("<b>Chapter</b>", S("mhh2", fontSize=8, textColor=GRAY_MID, fontName="Helvetica-Bold")),
        Paragraph("<b>1st Study ☐</b>", S("mhh3", fontSize=8, textColor=GRAY_MID, fontName="Helvetica-Bold", alignment=TA_CENTER)),
        Paragraph("<b>Revision ☐</b>", S("mhh4", fontSize=8, textColor=GRAY_MID, fontName="Helvetica-Bold", alignment=TA_CENTER)),
        Paragraph("<b>Confident ☐</b>", S("mhh5", fontSize=8, textColor=GRAY_MID, fontName="Helvetica-Bold", alignment=TA_CENTER)),
    ]]
    for i, ch in enumerate(chapters):
        rb = bg_col if i % 2 == 0 else white
        rows.append([
            Paragraph(f"{i+1}", S("mri", fontSize=8, textColor=GRAY_MID, fontName="Helvetica", alignment=TA_CENTER)),
            Paragraph(ch, S("mrc", fontSize=8.5, textColor=GRAY_TEXT, fontName="Helvetica")),
            Paragraph("☐  Date:______", S("mrcb", fontSize=8, textColor=GRAY_MID, fontName="Helvetica", alignment=TA_CENTER)),
            Paragraph("☐  Date:______", S("mrcb2", fontSize=8, textColor=GRAY_MID, fontName="Helvetica", alignment=TA_CENTER)),
            Paragraph("☐  Confident", S("mrcb3", fontSize=8, textColor=GRAY_MID, fontName="Helvetica", alignment=TA_CENTER)),
        ])

    mtbl = Table(rows, colWidths=[0.7*cm, 10.5*cm, 2.4*cm, 2.4*cm, 1.7*cm])
    row_bgs = [HexColor("#EEEEEE")] + [
        (bg_col if i % 2 == 0 else white) for i in range(len(chapters))
    ]
    mtbl.setStyle(TableStyle([
        ("ROWBACKGROUNDS", (0,0),(-1,-1), row_bgs),
        ("TOPPADDING",    (0,0),(-1,-1), 3),
        ("BOTTOMPADDING", (0,0),(-1,-1), 3),
        ("LEFTPADDING",   (0,0),(-1,-1), 4),
        ("GRID",          (0,0),(-1,-1), 0.25, HexColor("#DDDDDD")),
        ("FONTNAME",      (0,0),(-1,0),  "Helvetica-Bold"),
    ]))
    story.append(mtbl)
    story.append(Spacer(1, 0.35*cm))


# ════════════════════════════════════════════════════════════════════════════
# CLOSING PAGE
# ════════════════════════════════════════════════════════════════════════════
story.append(PageBreak())
story.append(Spacer(1, 1.5*cm))

closing_data = [[
    Paragraph("🏁  EXAM DAY: August 17, 2026", S("cl1",
        fontSize=20, textColor=white, fontName="Helvetica-Bold",
        alignment=TA_CENTER, leading=26)),
]]
closing_tbl = Table(closing_data, colWidths=[W-2.8*cm])
closing_tbl.setStyle(TableStyle([
    ("BACKGROUND",   (0,0),(-1,-1), NAVY),
    ("TOPPADDING",   (0,0),(-1,-1), 20),
    ("BOTTOMPADDING",(0,0),(-1,-1), 20),
]))
story.append(closing_tbl)
story.append(Spacer(1, 0.8*cm))

story.append(Paragraph(
    "You followed the schedule. You studied chapter by chapter, video first then book, and you revised with spaced repetition. Walk into that exam hall knowing you did the work.",
    S("clb", fontSize=11, textColor=GRAY_TEXT, fontName="Helvetica",
      alignment=TA_CENTER, leading=16)))

story.append(Spacer(1, 1.2*cm))

goal_data = [[Paragraph("MY GOAL FOR THIS EXAM:", S("gt",
    fontSize=12, textColor=NAVY, fontName="Helvetica-Bold", alignment=TA_CENTER))]]
goal_data += [[Paragraph("_"*90, S("gl", fontSize=10, textColor=HexColor("#CCCCCC"),
    fontName="Helvetica", alignment=TA_CENTER))] for _ in range(3)]
goal_tbl = Table(goal_data, colWidths=[W-2.8*cm])
goal_tbl.setStyle(TableStyle([
    ("BACKGROUND",   (0,0),(-1,-1), HexColor("#E8EAF6")),
    ("TOPPADDING",   (0,0),(-1,-1), 8),
    ("BOTTOMPADDING",(0,0),(-1,-1), 8),
    ("LEFTPADDING",  (0,0),(-1,-1), 20),
    ("LINEABOVE",    (0,0),(-1,-1), 2, NAVY_LIGHT),
]))
story.append(goal_tbl)
story.append(Spacer(1, 0.6*cm))
story.append(Paragraph(
    "Write your goal above. Read it every morning before you open your books.",
    S("mot", fontSize=9, textColor=GRAY_MID, fontName="Helvetica-Oblique",
      alignment=TA_CENTER)))

# ── Build ─────────────────────────────────────────────────────────────────────
doc.build(story, onFirstPage=make_canvas_cb("Cover"), onLaterPages=make_canvas_cb("Page"))
print(f"PDF saved: {OUT}")