Presentation on ketamine with full details and all the doses
Asking for Preferences
Reading File
Reading File
Reading File
Finding Sources
Searching PubMed
ketamine anesthesia clinical review
Reading File
Reading File
Reading File
Reading File
Reading File
Finding Sources
Reading File
Reading File
Reading File
Finding Sources
Finding Sources
Reading File
Finding Sources
Reading File
Running Command
Running Command
Writing File
Running Command
Running Command
Your presentation is ready. Download it here:
Ketamine Clinical Overview
Presentation · PPTX
What's inside (16 slides, ~986 KB)
| Slide | Content |
|---|---|
| 1 | Title slide — dark navy design with drug classification badges |
| 2 | Overview / Agenda — 12-topic navigation cards |
| 3 | History & Classification — visual timeline from 1956 to Spravato® 2019 |
| 4 | Mechanism of Action — 6 receptor-level mechanisms (NMDA, opioid, monoamine, sigma, mAChR, Na⁺ channel) |
| 5 | Pharmacokinetics & PD — full table: bioavailability by all routes, Vd, CYP metabolism, enantiomers, half-life |
| 6 | Dosing — ALL Routes & Indications — 17-row table covering induction, maintenance, PSA, RSI, analgesia, status epilepticus, TRD, esketamine (with auto-pagination) |
| 7 | Cardiovascular Effects — 6-box layout: stimulation, direct depression, S(+) specifics, ideal uses, cautions, how to blunt response |
| 8 | CNS & Respiratory Effects — side-by-side columns with EEG changes, ICP evidence, bronchodilation, apnoea risk |
| 9 | Clinical Indications — 8 clinical domains with detailed bullet points |
| 10 | Contraindications & Precautions — absolute vs relative + updated ICP evidence box |
| 11 | Adverse Effects & Management — 12-row table with frequencies and evidence-based management (NNB figures) |
| 12 | Drug Interactions — 11 interactions with severity coding (MAJOR/CAUTION/BENEFICIAL) |
| 13 | Special Populations — 6 groups: paediatrics, elderly, pregnancy, shock, hepatic impairment, asthma |
| 14 | Ketamine in Psychiatry — TRD mechanism, IV off-label dosing, Esketamine REMS protocol |
| 15 | Monitoring & Practical Tips — pre-procedure checklist, administration tips, intraoperative monitoring, recovery |
| 16 | Key Takeaways — 10 essential clinical pearls |
Sources: Miller's Anesthesia 10e, Goodman & Gilman's, Rosen's Emergency Medicine, Roberts & Hedges' Clinical Procedures in Emergency Medicine, Kaplan & Sadock's Comprehensive Textbook of Psychiatry, Harriet Lane Handbook, Barash's Clinical Anesthesia 9e.
This is a shared conversation. Sign in to Orris to start your own chat.