Steps to intubate a patient

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endotracheal intubation steps procedure RSI 2024

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Endotracheal Intubation: Step-by-Step Guide

The standard approach in emergency settings is Rapid Sequence Intubation (RSI), used in ~85% of all ED intubations. It is organized around the "7 Ps" framework.

Step 1 - Preparation

Assess the airway for difficulty (LEMON mnemonic: Look, Evaluate, Mallampati, Obstruction, Neck mobility). Check for:
  • Limited mouth opening
  • Short thyromental distance
  • Cervical spine immobility
  • Obesity, pregnancy, facial trauma, or airway swelling
Assemble equipment:
  • Laryngoscope (handle + blade) - direct (Macintosh/Miller) or video laryngoscope
  • Endotracheal tube (ETT) with stylet - typically 7.0-8.0 mm for adults
  • 10-12 mL syringe (for cuff inflation)
  • Bag-valve-mask (BVM) + oxygen source
  • Yankauer suction - turned on and at bedside
  • End-tidal CO2 (EtCO2) detector or capnography
  • Bougie (intubating stylet)
  • Tape or commercial tube holder
  • Cricothyrotomy kit - located and accessible
Establish access & monitoring:
  • IV access (minimum one, preferably two)
  • Continuous pulse oximetry and cardiac monitoring
  • Draw up and label all medications
  • Communicate the plan to the entire team, including a backup plan for failed airway
- Roberts and Hedges' Clinical Procedures in Emergency Medicine, Pre-Intubation Checklist

Step 2 - Preoxygenation

Goal: Replace nitrogen in the lungs (denitrogenation) to create an oxygen reservoir in the functional residual capacity (FRC), extending safe apnea time to 6-8 minutes in a healthy adult.
  • Apply high-flow oxygen at flush rate (40-70 L/min) via non-rebreather mask for 3-5 minutes - not just 15 L/min, which gives only ~65% FiO2
  • Simultaneously place a nasal cannula at 10-15 L/min for apneic oxygenation (passive O2 delivery during laryngoscopy)
  • Position the patient upright at 20-30° (reverse Trendelenburg) if possible - especially beneficial in obese patients, who desaturate fastest
  • At-risk for rapid desaturation: obese, pregnant, critically ill, pediatric patients
- Rosen's Emergency Medicine, p. 31 | Roberts and Hedges', Preoxygenation section

Step 3 - Preintubation Optimization

Address abnormal physiology before inducing:
  • Hypotension/shock: give IV fluids, blood products, or start vasopressors (norepinephrine) - induction agents cause vasoplegia and can precipitate circulatory collapse
  • Bronchospasm: nebulized albuterol
  • Severe acidosis: optimize ventilation if spontaneously breathing
  • Identify and treat any correctable physiology to improve the chance of surviving the peri-intubation period
- Rosen's Emergency Medicine, Preintubation Optimization

Step 4 - Paralysis with Induction (Drug Administration)

Administer sedative/induction agent by rapid IV push, immediately followed by the neuromuscular blocking agent (NMBA):
DrugDoseNotes
Ketamine (induction)1.5-2 mg/kg IVPreferred in hemodynamically unstable or bronchospasm
Etomidate (induction)0.3 mg/kg IVHemodynamically neutral
Propofol (induction)1.5-2 mg/kg IVUse with caution in hypotension
Succinylcholine (NMBA)1.5 mg/kg IVDepolarizing; onset 45-60 sec; avoid in hyperkalemia, burns >24h, crush injury, lower motor neuron disease
Rocuronium (NMBA)1.2 mg/kg IVNon-depolarizing; reversible with sugammadex 16 mg/kg; equivalent to succinylcholine at this dose
  • Do not bag the patient after induction unless SpO2 drops to <92%
  • Assess relaxation ~45-60 seconds post-NMBA by testing mandibular mobility
- Rosen's Emergency Medicine, Paralysis with Induction | VUMC RSI Guideline 2024

Step 5 - Positioning

  • Sniffing position: neck flexed on the body + head extended at the atlanto-occipital joint - aligns oral, pharyngeal, and laryngeal axes for direct laryngoscopy
  • In obese patients, elevate the head/upper torso significantly (ear-to-sternal-notch alignment)
  • Cervical spine precautions: if C-spine injury suspected, use in-line stabilization - do not extend the neck
  • Cricoid pressure (Sellick maneuver) is no longer recommended - it is frequently applied incorrectly and can worsen laryngoscopy
- Rosen's Emergency Medicine, Positioning

Step 6 - Placement of the Tube (Laryngoscopy)

Direct Laryngoscopy technique:
  1. Hold laryngoscope in the left hand
  2. Open the mouth with right hand (scissor technique)
  3. Insert blade into the right side of the mouth, sweeping the tongue to the left
    • Curved (Macintosh) blade: tip seats in the vallecula (just anterior to epiglottis); lift upward and forward along the axis of the handle
    • Straight (Miller) blade: tip goes under the epiglottis and lifts it directly
  4. Apply force in the direction of the laryngoscope handle (up and forward at ~45°) - do not lever back against the upper teeth
  5. Visualize the vocal cords / glottic opening
Grading the view (Cormack-Lehane):
  • Grade I: full glottis visible - easy
  • Grade II: posterior glottis visible - usually manageable
  • Grade III: only epiglottis seen - difficult; use bougie
  • Grade IV: epiglottis not visible - very difficult
Passing the tube: 6. With right hand, advance the ETT through the vocal cords under direct vision until the cuff is 2-3 cm past the cords (~23 cm at lip in males, ~21 cm in females) 7. Remove the stylet 8. Inflate the cuff with 5-10 mL air
If first pass is difficult: use a bougie - pass it through the cords, then railroad the ETT over it. The bougie is invaluable for Grade III views.
- Roberts and Hedges' Clinical Procedures in Emergency Medicine, Direct Laryngoscopy

Step 7 - Proof of Placement (Confirmation)

Never rely on a single method. Use all of the following:
  1. Waveform capnography / EtCO2 - gold standard; confirms CO2 from the lungs with 3 consistent waveforms
  2. Direct visualization of tube passing between the cords
  3. Bilateral chest rise with BVM ventilation
  4. Bilateral breath sounds (auscultate axillae first, then epigastrium - absent gurgling confirms non-esophageal placement)
  5. SpO2 maintained or improving
  6. Chest X-ray - after initial confirmation; ensures no mainstem (right) intubation; optimal ETT tip position is 2-4 cm above the carina
If esophageal intubation is suspected - remove the tube immediately, ventilate with BVM, and reattempt.
- Roberts and Hedges' Clinical Procedures in Emergency Medicine | Rosen's Emergency Medicine

Step 8 - Post-Intubation Management

  • Secure the tube: tape or commercial holder at confirmed depth
  • Initiate mechanical ventilation: typical starting settings - assist-control, tidal volume 6-8 mL/kg ideal body weight, RR 12-16, PEEP 5 cmH2O, FiO2 100% (then titrate down)
  • Continuous capnography: target EtCO2 35-45 mmHg (lower ~30 mmHg if ICP concern)
  • Sedation and analgesia: start long-acting sedation (e.g., propofol or midazolam infusion) + analgesia (fentanyl) - the NMBA will wear off
  • Orogastric tube: decompress the stomach
  • Check CXR: confirm tip position and check for pneumothorax

Quick Reference: Failed Airway Plan

Always have a backup plan before intubating:
  • BVM ventilation if SpO2 falls
  • Supraglottic airway (LMA / iGel) as rescue device
  • Video laryngoscopy if direct view is poor
  • Bougie for Grade III views
  • Cricothyrotomy (surgical or needle) if "cannot intubate, cannot oxygenate"

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