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Peripheral Nerve Injury Tests β Complete Guide
ποΈ MEDIAN NERVE TESTS
1. Tinel's Sign
Indication: Carpal tunnel syndrome (CTS) β and any median nerve compression
Technique: Gently tap (percuss) with two fingers over the carpal tunnel on the volar (palmar) surface of the wrist
Positive finding: Electric shock-like tingling shooting into the thumb, index, middle, and radial half of the ring finger
Mechanism: Percussion mechanically stimulates the irritated or regenerating median nerve fibers
2. Phalen's Test (Phalen's Maneuver)
Indication: Carpal tunnel syndrome
Technique: Patient holds both wrists in maximal flexion (dorsal hands pressed together, fingers pointing down) for 60 seconds. This constricts the transverse carpal ligament and narrows the tunnel.
Positive finding: Reproduction of numbness, tingling, or pain in the median nerve distribution within 30β60 seconds
3. Durkan Compression Test (Carpal Tunnel Compression Test)
Indication: Carpal tunnel syndrome β most sensitive provocative test for CTS
Technique: Examiner compresses the median nerve directly over the carpal tunnel (thumb on the palm, wrist in neutral) for up to 30β60 seconds
Positive finding: Reproduction of numbness, tingling, or pain in the median nerve distribution
"Most sensitive provocative test: carpal tunnel compression test (Durkan test) with wrist in neutral position" β Miller's Review of Orthopaedics, 9th Ed.
4. "OK Sign" / Anterior Interosseous Nerve Test
Indication: Anterior interosseous nerve (AIN) entrapment (purely motor branch of median nerve)
Technique: Ask the patient to form a circle (the "OK sign") with the thumb and index finger
Positive finding: Inability to flex the thumb IP joint and index DIP simultaneously β the patient instead forms a "pinch" posture (precision sign); no sensory loss
5. Abductor Pollicis Brevis (APB) Test
Indication: Median nerve motor branch integrity at the wrist (thenar branch)
Technique: Place thumb in palmar abduction (palm up); patient resists force directed toward the palm. Palpate the APB belly to confirm contraction.
Positive finding: Weakness of thumb opposition/abduction = motor branch compromise
"The best muscle to test in suspected carpal tunnel syndrome is the abductor pollicis brevis, which abducts the thumb perpendicular to the plane of the palm." β Neuroanatomy Through Clinical Cases, 3rd Ed.
β ULNAR NERVE TESTS
6. Tinel's Sign at the Elbow
Indication: Cubital tunnel syndrome (ulnar nerve at medial epicondyle)
Technique: Tap over the cubital tunnel at the medial epicondyle
Positive finding: Pain or paresthesias shooting down the ulnar border of the forearm into the 4th and 5th fingers
7. Elbow Flexion Test
Indication: Cubital tunnel syndrome
Technique: Hyperflexion of the elbow with shoulder flexed at 90Β°; maintain for 3 minutes. Elbow flexion tightens the cubital tunnel retinaculum and stretches the ulnar nerve.
Positive finding: Reproduction of pain, numbness, or tingling in the ulnar nerve distribution (5th and medial 4th finger)
8. Froment's Sign
Indication: Ulnar nerve palsy (specifically tests adductor pollicis, which is ulnar-innervated)
Technique: Ask the patient to hold a piece of paper in a lateral (key) pinch between thumb and radial side of the index finger. Attempt to pull the paper away.
Positive finding: Patient flexes the thumb at the IP joint (using flexor pollicis longus, median-innervated) to compensate for a paralyzed adductor pollicis. IP flexion = positive Froment's sign.
9. Wartenberg's Sign
Indication: Ulnar neuropathy
Technique: Observe the patient's small (5th) finger at rest
Positive finding: Persistent abduction/extension of the small finger during attempted adduction β due to weakness of the 3rd palmar interosseous (ulnar) and unopposed pull of the extensor digiti quinti (radial nerve)
10. Jeanne's Sign
Indication: Ulnar neuropathy
Technique: Observe thumb posture during key pinch
Positive finding: Thumb MCP hyperextension during key pinch β due to weak adductor pollicis (ulnar-innervated). Often accompanies Froment's sign.
"Froment: thumb IP flexion during key pinch. Jeanne: thumb MCP hyperextension during key pinch. Wartenberg: abduction/extension of small digit during attempted adduction." β Miller's Review of Orthopaedics, 9th Ed.
11. Finger Abduction/Spread Test
Indication: Ulnar intrinsic weakness
Technique: Ask patient to spread fingers apart or cross middle over index finger; resist force pushing them to midline
Positive finding: Weakness confirms ulnar nerve motor branch deficit at or above the wrist level
π¦Ύ RADIAL NERVE TESTS
12. Wrist/Finger Extension Test
Indication: Radial nerve palsy or posterior interosseous nerve (PIN) injury
Technique: Place patient's palm flat on a table; ask them to lift each finger straight up (hyperextend MCP joints) against resistance
Positive finding: Inability to hyperextend the finger MCP joints = radial nerve or PIN injury. If the patient can weakly extend the wrist in a radial direction (ECRL/ECRB spared) but not extend fingers β PIN palsy (radial nerve proper is intact)
Classic sign: "Wrist drop" β inability to extend the wrist against gravity
13. Extensor Pollicis Longus (EPL) Test
Indication: Radial nerve / PIN integrity
Technique: Ask patient to extend the thumb against resistance
Positive finding: Weakness or absence = PIN injury (EPL is innervated by the posterior interosseous nerve)
MEDIAN NERVE β Proximal Tests
14. Pronator Syndrome Provocative Tests
Indication: Median nerve compression in the proximal forearm (pronator teres level)
Three separate maneuvers isolate the compression site:
| Maneuver | Compression site |
|---|
| Resisted elbow flexion with forearm supinated | Bicipital aponeurosis (lacertus fibrosis) |
| Resisted forearm pronation with elbow extended | Between heads of pronator teres |
| Resisted long finger PIP flexion | FDS arch |
Key differentiator from CTS: Pronator syndrome causes sensory disturbances over the thenar eminence (palmar cutaneous branch, exits proximal to carpal tunnel); CTS spares thenar sensation.
π¦Ώ THORACIC OUTLET / LOWER LIMB NERVES
15. Adson Test
Indication: Thoracic outlet syndrome (vascular β subclavian vein/artery compression)
Technique: Patient hyperextends the neck and rotates it to the affected side; decreased radial pulse during inhalation
Positive finding: Diminished or absent radial pulse = positive
16. Peroneal Nerve Assessment
Indication: Deep peroneal nerve entrapment (fibular head, anterior tarsal tunnel)
Clinical sign: Foot drop (inability to dorsiflex the foot) + numbness in the web space between the 1st and 2nd toes
Causes: Proximal fibular fracture, habitual leg crossing, prolonged squatting
Summary Table
| Test | Nerve | Site Tested | Positive Finding |
|---|
| Tinel's sign (wrist) | Median | Carpal tunnel | Tingling in digits 1β3.5 |
| Phalen's test | Median | Carpal tunnel | Tingling in digits 1β3.5 after 60 s wrist flexion |
| Durkan compression test | Median | Carpal tunnel | Tingling in digits 1β3.5 (most sensitive) |
| "OK sign" / AIN test | Median (AIN) | Forearm | Can't form circle β motor loss, no sensory loss |
| Tinel's sign (elbow) | Ulnar | Cubital tunnel | Tingling in digits 4β5 |
| Elbow flexion test | Ulnar | Cubital tunnel | Tingling in digits 4β5 within 3 min |
| Froment's sign | Ulnar | Adductor pollicis | Thumb IP flexion during key pinch |
| Wartenberg's sign | Ulnar | 3rd palmar interosseous | Small finger abduction at rest |
| Jeanne's sign | Ulnar | Adductor pollicis | Thumb MCP hyperextension during key pinch |
| Wrist drop / MCP extension | Radial | Spiral groove / PIN | No wrist/finger extension |
| Adson test | Brachial plexus | Thoracic outlet | Reduced radial pulse |
| Foot drop exam | Deep peroneal | Fibular head | Cannot dorsiflex foot |
Sources:
- Sabiston Textbook of Surgery, 21st Ed. β Table 119.3
- Miller's Review of Orthopaedics, 9th Ed. β Tables 7.8 and Compression Neuropathy section
- Tintinalli's Emergency Medicine, 9th Ed. β Focal Mononeuropathies chapter
- Neuroanatomy Through Clinical Cases, 3rd Ed. β Upper Extremity Nerve Injuries
- Thieme Atlas of Anatomy β General Anatomy and Musculoskeletal System