Common Conditions at RHTC and Their Symptomatic Treatment (Age-Wise)

from reportlab.lib.pagesizes import A5
from reportlab.lib import colors
from reportlab.lib.units import mm
from reportlab.lib.styles import getSampleStyleSheet, ParagraphStyle
from reportlab.lib.enums import TA_CENTER, TA_LEFT
from reportlab.platypus import (
    SimpleDocTemplate, Table, TableStyle, Paragraph, Spacer,
    HRFlowable, KeepTogether
)
from reportlab.lib.colors import HexColor

OUTPUT = "/home/daytona/workspace/rhtc-pocket-guide/RHTC_Pocket_Guide.pdf"

# ── Colour palette ──────────────────────────────────────────────────────────
C_NAVY   = HexColor("#1a3a5c")   # header background
C_TEAL   = HexColor("#0d7377")   # section title background
C_MINT   = HexColor("#e8f5f5")   # table alt row
C_AMBER  = HexColor("#fff3cd")   # warning / note row
C_RED    = HexColor("#c0392b")   # red-flag text
C_WHITE  = colors.white
C_BLACK  = colors.black
C_LGRAY  = HexColor("#f5f5f5")
C_DGRAY  = HexColor("#555555")

doc = SimpleDocTemplate(
    OUTPUT,
    pagesize=A5,
    leftMargin=8*mm, rightMargin=8*mm,
    topMargin=8*mm, bottomMargin=8*mm,
)

W = A5[0] - 16*mm   # usable width

styles = getSampleStyleSheet()

def style(name, parent="Normal", **kwargs):
    return ParagraphStyle(name, parent=styles[parent], **kwargs)

S_TITLE   = style("Title2",   fontSize=13, textColor=C_WHITE, alignment=TA_CENTER, leading=16, fontName="Helvetica-Bold")
S_HEAD    = style("Head2",    fontSize=8,  textColor=C_WHITE, alignment=TA_CENTER, leading=10, fontName="Helvetica-Bold")
S_CELL    = style("Cell2",    fontSize=7,  textColor=C_BLACK, alignment=TA_LEFT,   leading=9,  fontName="Helvetica")
S_CELLB   = style("CellB2",   fontSize=7,  textColor=C_BLACK, alignment=TA_LEFT,   leading=9,  fontName="Helvetica-Bold")
S_NOTE    = style("Note2",    fontSize=6.5,textColor=C_DGRAY, alignment=TA_LEFT,   leading=8,  fontName="Helvetica-Oblique")
S_RED     = style("Red2",     fontSize=6.5,textColor=C_RED,   alignment=TA_LEFT,   leading=8,  fontName="Helvetica-Bold")
S_SEC     = style("Sec2",     fontSize=8,  textColor=C_WHITE, alignment=TA_LEFT,   leading=10, fontName="Helvetica-Bold")
S_FOOTER  = style("Footer2",  fontSize=5.5,textColor=C_DGRAY, alignment=TA_CENTER, leading=7,  fontName="Helvetica-Oblique")

# ── Helper: section header bar ───────────────────────────────────────────────
def sec_header(text, color=C_TEAL):
    data = [[Paragraph(f"▶  {text}", S_SEC)]]
    t = Table(data, colWidths=[W])
    t.setStyle(TableStyle([
        ("BACKGROUND", (0,0), (-1,-1), color),
        ("TOPPADDING",  (0,0), (-1,-1), 3),
        ("BOTTOMPADDING",(0,0),(-1,-1), 3),
        ("LEFTPADDING", (0,0), (-1,-1), 5),
        ("RIGHTPADDING",(0,0), (-1,-1), 5),
    ]))
    return t

# ── Helper: plain table ──────────────────────────────────────────────────────
def make_table(headers, rows, col_widths, alt=True, note=None):
    """Build a styled table with optional note row."""
    head_row = [Paragraph(h, S_HEAD) for h in headers]
    body = [head_row]
    for i, row in enumerate(rows):
        styled = [Paragraph(str(c), S_CELLB if i == 0 and False else S_CELL) for c in row]
        body.append(styled)

    style_cmds = [
        ("BACKGROUND",    (0,0),  (-1,0),  C_NAVY),
        ("ROWBACKGROUNDS",(0,1),  (-1,-1), [C_WHITE, C_MINT] if alt else [C_WHITE]),
        ("GRID",          (0,0),  (-1,-1), 0.3, HexColor("#cccccc")),
        ("TOPPADDING",    (0,0),  (-1,-1), 2),
        ("BOTTOMPADDING", (0,0),  (-1,-1), 2),
        ("LEFTPADDING",   (0,0),  (-1,-1), 3),
        ("RIGHTPADDING",  (0,0),  (-1,-1), 3),
        ("VALIGN",        (0,0),  (-1,-1), "MIDDLE"),
        ("FONTSIZE",      (0,0),  (-1,0),  7),
    ]
    t = Table(body, colWidths=col_widths)
    t.setStyle(TableStyle(style_cmds))
    elems = [t]
    if note:
        elems.append(Paragraph(note, S_NOTE))
    return elems

# ── Helper: note/warning box ─────────────────────────────────────────────────
def note_box(text, bg=C_AMBER, text_style=None):
    s = text_style or S_NOTE
    data = [[Paragraph(text, s)]]
    t = Table(data, colWidths=[W])
    t.setStyle(TableStyle([
        ("BACKGROUND",    (0,0), (-1,-1), bg),
        ("TOPPADDING",    (0,0), (-1,-1), 3),
        ("BOTTOMPADDING", (0,0), (-1,-1), 3),
        ("LEFTPADDING",   (0,0), (-1,-1), 5),
        ("RIGHTPADDING",  (0,0), (-1,-1), 5),
        ("BOX",           (0,0), (-1,-1), 0.5, C_TEAL),
    ]))
    return t

# ════════════════════════════════════════════════════════════════════════════
# Build story
# ════════════════════════════════════════════════════════════════════════════
story = []
SP = lambda n=2: Spacer(1, n*mm)
HR = lambda: HRFlowable(width=W, thickness=0.4, color=HexColor("#cccccc"), spaceAfter=1*mm, spaceBefore=1*mm)

# ── Cover banner ─────────────────────────────────────────────────────────────
banner_data = [[Paragraph("RHTC INTERN POCKET GUIDE", S_TITLE)],
               [Paragraph("Quick Reference · Dosing Tables · Red Flags", style("sub", fontSize=7, textColor=C_WHITE, alignment=TA_CENTER, fontName="Helvetica"))]]
banner = Table(banner_data, colWidths=[W])
banner.setStyle(TableStyle([
    ("BACKGROUND",    (0,0), (-1,-1), C_NAVY),
    ("TOPPADDING",    (0,0), (-1,-1), 5),
    ("BOTTOMPADDING", (0,0), (-1,-1), 5),
    ("LEFTPADDING",   (0,0), (-1,-1), 4),
    ("RIGHTPADDING",  (0,0), (-1,-1), 4),
]))
story += [banner, SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 1. ACUTE DIARRHEA
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("1. ACUTE DIARRHEA / GASTROENTERITIS"), SP()]
story += make_table(
    ["Age", "ORS per loose stool", "Zinc (14 days)"],
    [
        ["< 6 months",         "50–100 mL",      "10 mg/day"],
        ["6 months – 2 yrs",   "100–200 mL",     "20 mg/day"],
        ["2 – 10 yrs",         "100–200 mL",     "20 mg/day"],
        ["> 10 yrs / Adults",  "200–400 mL",     "Not needed"],
    ],
    [30*mm, 60*mm, W-90*mm]
)
story += [SP(), note_box(
    "Antibiotics ONLY if: cholera-suspect → Doxycycline 300mg single dose (adults) / Cotrimoxazole in children  |  "
    "Bloody diarrhea/dysentery → Ciprofloxacin 500mg BD×3d (adults); Nalidixic acid in children  |  "
    "Amoebiasis/Giardiasis → Metronidazole 400mg TDS×5–7d"
), SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 2. FEVER / ARI
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("2. FEVER & UPPER RESPIRATORY INFECTION (URTI)"), SP()]
story += make_table(
    ["Age", "Paracetamol", "Antihistamine"],
    [
        ["< 2 yrs",       "10–15 mg/kg/dose Q6H",     "Saline nasal drops only"],
        ["2–12 yrs",      "10–15 mg/kg/dose Q6H",     "CPM 0.1 mg/kg/dose BD"],
        ["Adults",        "500 mg–1 g Q6H (max 4g/d)","Cetirizine 10mg OD or CPM 4mg TDS"],
    ],
    [25*mm, 60*mm, W-85*mm]
)
story += [SP(), note_box(
    "Antibiotics if bacterial (fever>3d, purulent exudate, ear pain): Amoxicillin 500mg TDS (adults) / 25–40mg/kg/day ÷3 (children) ×7d  |  "
    "Pneumonia (tachypnea+fever+chest signs): same dose; REFER if chest indrawing, cyanosis or SpO₂ <94%"
), SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 3. MALARIA
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("3. MALARIA  (Confirm with RDT / smear first)"), SP()]
story.append(Paragraph("<b>P. vivax</b> — Chloroquine (CQ 150mg base tab) + Primaquine (PQ 2.5mg tab)", S_CELLB))
story += [SP(1)]
story += make_table(
    ["Age", "CQ Day1", "CQ Day2", "CQ Day3", "PQ Days 1–14"],
    [
        ["<1 yr",        "½",  "½",  "¼",    "Contraindicated"],
        ["1–4 yrs",      "1",  "1",  "½",    "1 tab/day"],
        ["5–8 yrs",      "2",  "2",  "1",    "2 tabs/day"],
        ["9–14 yrs",     "3",  "3",  "1½",   "4 tabs/day"],
        ["≥15 yrs/Adult","4",  "4",  "2",    "6 tabs/day"],
        ["Pregnancy",    "4",  "4",  "2",    "⚠ OMIT PQ"],
    ],
    [32*mm, 18*mm, 18*mm, 18*mm, W-86*mm]
)
story += [SP(2)]
story.append(Paragraph("<b>P. falciparum</b> — ACT-SP (non-NE India)", S_CELLB))
story += [SP(1)]
story += make_table(
    ["Age", "Artesunate (50mg) Days 1–3", "SP Day 1", "PQ (large) Day 2"],
    [
        ["<1 yr",          "¼ tab/day",    "¼",   "Contraindicated"],
        ["1–4 yrs",        "½ tab/day",    "½",   "½ tab"],
        ["5–8 yrs",        "1 tab/day",    "1",   "¾ tab"],
        ["9–14 yrs",       "2 tabs/day",   "1½",  "1½ tabs"],
        ["≥15 yrs/Adult",  "4 tabs/day",   "3",   "2 tabs (45mg)"],
        ["Pregnancy",      "4 tabs/day",   "3",   "⚠ OMIT PQ (1st tri: avoid ACT)"],
    ],
    [24*mm, 52*mm, 18*mm, W-94*mm]
)
story += [SP(), note_box(
    "⚠  PQ contraindicated: infants, pregnancy, G6PD deficiency  |  "
    "Severe malaria → IV Artesunate: REFER immediately  |  "
    "Always give paracetamol for fever control"
), SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 4. ENTERIC FEVER
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("4. ENTERIC FEVER (TYPHOID)"), SP()]
story += make_table(
    ["Group", "Drug & Dose", "Duration"],
    [
        ["Adults",      "Ciprofloxacin 500mg BD  OR  Azithromycin 1g Day1 then 500mg OD", "14d / 7d"],
        ["Children",    "Azithromycin 20mg/kg/day OD  OR  Cefixime 20mg/kg/day BD",       "7d / 14d"],
        ["Pregnancy",   "Ceftriaxone 2g IV OD — REFER",                                    "14d"],
    ],
    [25*mm, 100*mm, W-125*mm]
)
story += [SP(), note_box(
    "Symptomatic: Paracetamol for fever; soft diet; ORS  |  Avoid NSAIDs (GI bleed/perforation risk)"
), SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 5. ANEMIA (Iron Deficiency)
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("5. IRON DEFICIENCY ANEMIA"), SP()]
story += make_table(
    ["Group", "Elemental Iron + Folic Acid", "Duration"],
    [
        ["Children 6m–5yr",        "Ferrous sulfate 3mg/kg/day ÷2 doses",           "3–6 months"],
        ["5–12 yrs",               "60mg Fe + 0.5mg FA once daily",                  "3 months"],
        ["Adolescent girls (WIFS)","100mg Fe + 0.5mg FA once weekly (school)",       "Ongoing"],
        ["Pregnant women (IFA)",   "100mg Fe + 0.5mg FA twice daily",                "Pregnancy + 3m PP"],
        ["Adults (general)",       "100–200mg Fe daily (divided doses)",              "3–6 months"],
    ],
    [40*mm, 88*mm, W-128*mm]
)
story += [SP(), note_box(
    "Give iron between meals for better absorption; take with lemon juice (Vit C)  |  "
    "Deworming at start: Albendazole 400mg single dose (children >2yr & adults)"
), SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 6. WORM INFESTATION
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("6. INTESTINAL WORMS (Deworming)"), SP()]
story += make_table(
    ["Age", "Drug", "Dose"],
    [
        ["1–2 yrs",              "Albendazole",   "200mg single dose"],
        [">2 yrs & Adults",      "Albendazole",   "400mg single dose"],
        ["Alternative (all)",    "Mebendazole",   "500mg single dose  OR  100mg BD × 3d"],
    ],
    [38*mm, 42*mm, W-80*mm]
)
story += [SP(), note_box("Repeat every 6 months (National Deworming Day)  |  Always pair with iron supplementation if anemia"), SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 7. SCABIES
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("7. SCABIES"), SP()]
story += make_table(
    ["Age", "Treatment"],
    [
        ["<2 months",          "5–10% Sulfur ointment — all over body (below neck) × 3 nights"],
        ["2m – 2 yrs",         "5% Permethrin cream — apply neck to toe, wash off after 8–12h; repeat in 1 week"],
        [">2 yrs & Adults",    "5% Permethrin  OR  Benzyl Benzoate 25% (dilute to 12.5% for children)"],
        ["Adults alt.",        "Ivermectin 200 mcg/kg single dose (not in pregnancy / weight <15kg)"],
    ],
    [35*mm, W-35*mm]
)
story += [SP(), note_box(
    "TREAT ALL FAMILY MEMBERS SIMULTANEOUSLY  |  "
    "Wash + hot-press all clothing & bedding  |  CPM for itch  |  Amoxicillin/Cloxacillin if secondary infection"
), SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 8. SKIN FUNGAL (TINEA)
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("8. FUNGAL SKIN INFECTION (TINEA)"), SP()]
story += make_table(
    ["Type", "Treatment"],
    [
        ["Localised (tinea corporis/cruris/pedis)", "Clotrimazole 1% cream BD × 2–4 weeks (topical)"],
        ["Extensive / scalp (tinea capitis)",       "Griseofulvin 10–20mg/kg/day (children) OR Fluconazole 150mg weekly × 4wk (adults)"],
        ["Nail (onychomycosis)",                    "Itraconazole 200mg OD × 3m OR pulse therapy"],
    ],
    [55*mm, W-55*mm]
)
story += [SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 9. HYPERTENSION
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("9. HYPERTENSION"), SP()]
story += make_table(
    ["Group", "First-line Drug"],
    [
        ["Adults <60yr",          "Amlodipine 2.5–5mg OD; if uncontrolled add Enalapril 5–10mg BD"],
        ["Elderly >60yr",         "Amlodipine 2.5mg OD (start low); avoid ACEI if dry cough"],
        ["With Diabetes",         "ACEI — Enalapril 5–10mg BD (or ARB: Losartan 50mg OD)"],
        ["Pregnancy",             "Methyldopa 250mg BD–TDS  OR  Labetalol 100mg BD"],
        ["Hypertensive urgency",  "Amlodipine 5–10mg; Enalapril; oral Nifedipine 10mg if needed"],
    ],
    [42*mm, W-42*mm]
)
story += [SP(), note_box(
    "Lifestyle: salt <5g/day; reduce alcohol; weight loss; walking 30min/day  |  "
    "BP >180/120 with symptoms → same-day treatment + close monitoring / refer"
), SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 10. DIABETES MELLITUS TYPE 2
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("10. DIABETES MELLITUS TYPE 2"), SP()]
story += make_table(
    ["Group", "Drug & Dose"],
    [
        ["Adults (non-obese)",  "Metformin 500mg OD with meals → titrate to 500mg TDS over weeks"],
        ["Adults (obese)",      "Metformin 500mg–1g BD (start low to avoid GI upset)"],
        ["Elderly",             "Metformin with caution (hold if eGFR <30); Glipizide 5mg OD"],
        ["Children (Type 1)",   "REFER — requires insulin"],
    ],
    [38*mm, W-38*mm]
)
story += [SP(), note_box(
    "Targets: FBS <126mg/dL; HbA1c <7%  |  "
    "Diet: avoid white rice excess, sugary drinks, processed foods  |  Screen: eyes, feet, BP, urine protein at every visit"
), SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 11. UTI
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("11. URINARY TRACT INFECTION (UTI)"), SP()]
story += make_table(
    ["Group", "Drug & Dose", "Duration"],
    [
        ["Non-pregnant women",  "Nitrofurantoin 100mg BD  OR  Cotrimoxazole DS BD",      "5d / 3d"],
        ["Pregnant women",      "Nitrofurantoin 100mg BD (avoid near term)  OR  Cephalexin 500mg QID", "7d"],
        ["Men / complicated",   "Ciprofloxacin 500mg BD",                                 "7–14d"],
        ["Elderly",             "Ciprofloxacin 500mg BD + ensure adequate hydration",      "7d"],
    ],
    [38*mm, 90*mm, W-128*mm]
)
story += [SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 12. EYE — ACUTE CONJUNCTIVITIS
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("12. ACUTE CONJUNCTIVITIS"), SP()]
story += make_table(
    ["Type", "Treatment"],
    [
        ["Bacterial (all ages)", "Ciprofloxacin 0.3% eye drops 1–2 drops Q2–4H × 7d"],
        ["Allergic",             "Sodium cromoglycate drops + Cetirizine 10mg OD (adults) / CPM (children)"],
        ["Neonatal (<28 days)",  "REFER IMMEDIATELY — Erythromycin/tetracycline ointment + systemic antibiotics"],
    ],
    [42*mm, W-42*mm]
)
story += [SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 13. MUSCULOSKELETAL PAIN
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("13. MUSCULOSKELETAL / JOINT PAIN"), SP()]
story += make_table(
    ["Condition", "Treatment"],
    [
        ["Osteoarthritis",    "Paracetamol 500mg–1g TDS (safer than NSAIDs in elderly) + topical Diclofenac gel"],
        ["Acute sprains",     "RICE + Ibuprofen 400mg TDS × 5d with food; Paracetamol if gastric issues"],
        ["Mechanical backache","Paracetamol + physiotherapy counseling; avoid prolonged bed rest"],
    ],
    [38*mm, W-38*mm]
)
story += [SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# 14. MALNUTRITION (Children)
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("14. MALNUTRITION (Children <5 years)"), SP()]
story += make_table(
    ["MUAC", "Grade", "Action"],
    [
        [">12.5 cm",      "Normal",  "Dietary counseling, routine care"],
        ["11.5–12.5 cm",  "MAM",     "High-energy diet counseling; micronutrients; deworming"],
        ["<11.5 cm",      "SAM",     "REFER to NRC; F75→F100 feeds; treat infection"],
    ],
    [22*mm, 22*mm, W-44*mm]
)
story += [SP(), note_box(
    "Vitamin A supplementation: 1,00,000 IU (6–11m) / 2,00,000 IU (1–5yr) every 6 months  |  "
    "Zinc 20mg/day × 14d for every diarrheal episode  |  Deworming every 6 months"
), SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# RED FLAGS
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("🚨  RED FLAGS — WHEN TO REFER", color=C_RED)]
story += [SP()]
story += make_table(
    ["Condition", "Refer if..."],
    [
        ["Diarrhea",         "Unable to drink, sunken eyes, no urine output, altered sensorium"],
        ["Malaria / Fever",  "Altered consciousness, convulsions, severe anemia, jaundice, hyperparasitemia"],
        ["ARI / Pneumonia",  "Chest indrawing, stridor, cyanosis, SpO₂ <92%, unable to feed"],
        ["Malnutrition",     "SAM + complications (infection, edema, hypoglycemia)"],
        ["Hypertension",     "BP >180/120 with headache / visual changes / confusion"],
        ["Pregnancy",        "Heavy bleeding, eclampsia, obstructed labor, fetal distress"],
        ["Eye",              "Neonatal conjunctivitis, corneal ulcer, sudden vision loss"],
    ],
    [38*mm, W-38*mm]
)
story += [SP(3)]

# ════════════════════════════════════════════════════════════════════════════
# QUICK TIPS
# ════════════════════════════════════════════════════════════════════════════
story += [sec_header("INTERN QUICK TIPS"), SP()]
tips = [
    "Always confirm malaria with RDT before prescribing antimalarials",
    "ORS first in every diarrhea — antibiotics rarely needed",
    "Zinc 14 days after every diarrheal episode in children <5yr",
    "Deworming every 6 months — combine with iron supplementation",
    "PQ contraindicated: infants, pregnancy, G6PD deficiency",
    "Scabies: treat ALL family members on the SAME day",
    "Metformin: start low (500mg OD) and titrate slowly",
    "WIFS scheme: weekly IFA for adolescent girls — record in register",
    "MUAC tape at every under-5 visit for malnutrition screening",
    "Document everything in OPD register for national health data",
]
tip_data = [[Paragraph(f"• {t}", S_CELL)] for t in tips]
tip_table = Table(tip_data, colWidths=[W])
tip_table.setStyle(TableStyle([
    ("ROWBACKGROUNDS", (0,0), (-1,-1), [C_WHITE, C_LGRAY]),
    ("TOPPADDING",     (0,0), (-1,-1), 2),
    ("BOTTOMPADDING",  (0,0), (-1,-1), 2),
    ("LEFTPADDING",    (0,0), (-1,-1), 5),
    ("RIGHTPADDING",   (0,0), (-1,-1), 5),
    ("BOX",            (0,0), (-1,-1), 0.3, C_TEAL),
]))
story.append(tip_table)
story += [SP(4)]

# ── Footer ───────────────────────────────────────────────────────────────────
story.append(Paragraph(
    "Sources: Park's PSM · Katzung Pharmacology · National Malaria Programme · WHO ARI/Diarrhea Guidelines · WIFS/NDD National Programmes  |  For educational use — always verify with current guidelines",
    S_FOOTER
))

# ── Build ─────────────────────────────────────────────────────────────────────
doc.build(story)
print("PDF generated:", OUTPUT)