Here is a complete explanation of LBBB:
Left Bundle Branch Block (LBBB)
The Normal Conduction System (Background)
In a normal heart, the electrical signal travels from the SA node → AV node → His bundle → then splits into two pathways:
- Right bundle branch → activates the right ventricle
- Left bundle branch → activates the left ventricle
Both ventricles depolarise almost simultaneously, producing a narrow QRS complex (<120 ms).
What Happens in LBBB
The left bundle branch is blocked or diseased, so the electrical signal cannot travel down it normally. Instead:
- The right ventricle activates first (via the right bundle branch, normally)
- The electrical signal then spreads slowly, cell-to-cell across the septum to reach the left ventricle
- This delayed, abnormal activation of the left ventricle produces a wide, abnormal QRS complex (≥120 ms)
This causes the two ventricles to contract out of sync - called ventricular dyssynchrony - which can reduce pumping efficiency over time.
How LBBB Looks on ECG
As described in
Harrison's Principles of Internal Medicine 22E, LBBB alters both early and later phases of ventricular depolarisation:
| Lead | What You See in LBBB |
|---|
| V1 | Broad, deep negative (QS or rS) complex |
| V6, I, aVL | Broad, tall, often notched R wave (no Q wave) |
| ST-T waves | Discordant - opposite direction to QRS |
| QRS duration | ≥120 ms (complete LBBB) |
The T-axis of -44° seen in this patient's ECG is a classic example of this discordance.
Causes of LBBB
LBBB almost always indicates underlying structural heart disease (unlike RBBB which can be benign):
- Hypertensive heart disease - most common cause, especially in elderly women
- Coronary artery disease - ischaemia damages the conduction tissue
- Dilated cardiomyopathy - stretched, diseased myocardium
- Aortic valve disease - the left bundle runs close to the aortic root
- Age-related fibrosis (Lev's disease / Lenegre's disease) - the conduction system scars with age
- Acute MI - new LBBB in the setting of chest pain is treated as a STEMI-equivalent
Why LBBB Matters
- Masking: LBBB makes it very difficult to diagnose MI on ECG because normal ST-T analysis cannot be applied - the ST changes are expected as a consequence of the block itself
- Dyssynchrony: The two ventricles contract out of sequence, which can weaken heart function over time
- Risk marker: Even asymptomatic LBBB is associated with increased cardiovascular mortality
- Treatment implications: In patients with heart failure + LBBB + reduced ejection fraction (EF <35%), Cardiac Resynchronisation Therapy (CRT) - a special pacemaker that paces both ventricles simultaneously - can restore synchrony and significantly improve outcomes (as noted in Goldman-Cecil Medicine)
Complete vs. Incomplete LBBB
| Type | QRS Duration |
|---|
| Complete LBBB | ≥120 ms |
| Incomplete LBBB | 110-119 ms |
This patient's QRS of 126 ms just meets the criteria for complete LBBB.
Simple Analogy
Think of the heart's electrical system like a two-lane highway. In LBBB, the left lane is blocked. Traffic (electrical signal) all has to go through the right lane first, then slowly creep over to the left side via side roads - arriving late and causing the left ventricle to contract with a delay.