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MRI Spine Analysis - Subhas Banduri, 41 years | Kolkata Medical College


Patient & Study Details

  • Patient: Subhas Banduri, ~41 years
  • Institution: Suraksha, Kolkata Medical College
  • Modality: MRI Spine (Philips scanner)
  • Film: 1 of 1 - Sagittal images of the thoracic and lumbar spine

Sequences Identified

RowSequenceKey Signal Characteristics
Top rowT2-weighted sagittalCSF bright (white), excellent for cord signal changes, edema, disc disease
Bottom rowT1-weighted sagittalCSF dark, bone marrow fat bright - best for marrow infiltration and anatomy

Key Pathological Findings

1. Vertebral Destruction and Collapse (Mid-Upper Thoracic - ~T5-T7)

  • At least two adjacent vertebral bodies show severe destruction, fragmentation, and height loss (pathological collapse)
  • On T1: Normal bright fatty marrow signal is completely replaced by hypointense (dark) signal - indicating infiltration, edema, or inflammatory/tumor replacement
  • On T2: Affected vertebrae show heterogeneous hyperintensity consistent with active pathology (inflammation, fluid, or neoplastic tissue)
  • The intervertebral disc space between the collapsed levels is poorly defined, narrowed, and appears destroyed

2. Epidural Mass with Severe Spinal Cord Compression

  • A prominent lobulated epidural soft tissue mass extends posteriorly from the destroyed vertebrae into the spinal canal
  • This causes severe spinal canal stenosis at the affected levels
  • The spinal cord is severely compressed and posteriorly displaced, with the normal CSF space around the cord completely obliterated (complete CSF block)
  • On T2 images, there is increased intramedullary signal at and above the compression level - indicating compressive myelopathy (cord edema or myelomalacia)

3. Paravertebral Soft Tissue Extension

  • Anterior and prevertebral soft tissue thickening/mass is visible adjacent to the collapsed vertebrae
  • This can represent a cold abscess (typical of tuberculosis) or aggressive tumor extension

4. Lower Thoracic and Lumbar Spine (Bottom Row)

  • The lumbar spine shows disc desiccation at multiple levels (reduced T2 signal in discs), consistent with degenerative disc disease
  • Disc height is relatively preserved at the lumbar levels
  • No obvious lumbar cord compression is identified on these images

Differential Diagnosis

Given the pattern of adjacent vertebral body destruction, disc space obliteration, large epidural/prevertebral soft tissue mass, and the geographic context (India, 41-year-old):
RankDiagnosisSupporting Features
1stSpinal Tuberculosis (Pott's Disease)Most common cause in India; classic involvement of 2 adjacent vertebrae with disc destruction, cold abscess, kyphotic deformity, and cord compression
2ndMetastatic spinal diseaseVertebral destruction + epidural extension, but metastases typically spare the disc until late
3rdPyogenic spondylodiscitisSimilar imaging but usually more acute; less common to cause this degree of chronic deformity

Clinical Significance - URGENT

This MRI demonstrates a critical finding. The patient is likely presenting with or is at high risk for:
  • Paraparesis or paraplegia (bilateral lower limb weakness)
  • Sensory level deficit below the compression
  • Bladder and bowel dysfunction (neurogenic)
Immediate spine surgery/neurosurgery consultation is required. Management for confirmed Pott's disease typically involves anti-tubercular therapy (ATT) for 12-18 months plus surgical decompression (corpectomy, fusion) when there is neurological compromise or spinal instability.

Disclaimer: This is an AI-assisted radiological analysis for educational and preliminary reference purposes only. A qualified radiologist and treating clinician must review the original DICOM images and correlate with the patient's clinical history, examination, and laboratory data before making any management decisions.
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