cd /home/daytona/skills/pptx && python -m markitdown /home/daytona/workspace/att…

ls /home/daytona/skills/pptx/scripts/ && python /home/daytona/skills/pptx/script…

python /home/daytona/skills/pptx/scripts/office/unpack.py /home/daytona/workspac…

mkdir -p /home/daytona/workspace/nhlirb-pptx && ls /home/daytona/workspace/nhlir…

ls /home/daytona/workspace/nhlirb-pptx/unpacked/ 2>&1 | head -30

ls /home/daytona/workspace/nhlirb-pptx/unpacked/ppt/slides/ 2>&1

cat /home/daytona/workspace/nhlirb-pptx/unpacked/ppt/presentation.xml | grep -o …

for i in 1 2 3 4 5 6 7 8 9; do echo "=== SLIDE $i ==="; python3 -c " import xml.…

ls /home/daytona/workspace/nhlirb-pptx/unpacked/ppt/slideLayouts/ | head -5; ech…

python3 -c " import xml.etree.ElementTree as ET tree = ET.parse('/home/daytona/w…

cat > /home/daytona/workspace/nhlirb-pptx/unpacked/ppt/slides/slide1.xml << 'XML…

python3 << 'PYEOF' import os BASE = "/home/daytona/workspace/nhlirb-pptx/unpack…

python /home/daytona/skills/pptx/scripts/clean.py /home/daytona/workspace/nhlirb…

pip install --user lxml -q 2>&1 | tail -3 && python /home/daytona/skills/pptx/sc…

python3 << 'PYEOF' import os, re BASE = "/home/daytona/workspace/nhlirb-pptx/un…

python3 << 'PYEOF' import pdfplumber pdf_path = "/home/daytona/workspace/attach…

mkdir -p /home/daytona/workspace/ayushi-irb && ls /home/daytona/workspace/ayushi…

~/ayushi-irb/build.js

const pptxgen = require("pptxgenjs");

const pres = new pptxgen();
pres.layout = "LAYOUT_16x9";
pres.title = "A Study of Red Cell Distribution Width as a Prognostic Marker in Patients with Heart Failure";

// NHLIRB guidelines:
// White background, Calibri font, black text
// Title slide heading: 30pt Bold
// Slide headings: 28pt Bold
// Sub-headings: 24pt Bold
// Body text: 22pt
// References: 18pt

const WHITE = "FFFFFF";
const BLACK = "000000";
const FONT = "Calibri";

// Helper: add a slide with title + body
function addContentSlide(title, bodyItems) {
  const slide = pres.addSlide();
  slide.background = { color: WHITE };

  // Slide title
  slide.addText(title, {
    x: 0.4, y: 0.2, w: 9.2, h: 0.65,
    fontFace: FONT, fontSize: 28, bold: true, color: BLACK,
    align: "left", valign: "middle",
    margin: 0
  });

  // Thin separator line under title
  slide.addShape(pres.ShapeType.line, {
    x: 0.4, y: 0.95, w: 9.2, h: 0,
    line: { color: BLACK, width: 1 }
  });

  // Build rich text array
  const richText = [];
  bodyItems.forEach((item, idx) => {
    const isLast = idx === bodyItems.length - 1;
    if (item.type === "subheading") {
      richText.push({
        text: item.text,
        options: {
          bold: true, fontSize: 24, fontFace: FONT, color: BLACK,
          bullet: false, breakLine: !isLast,
          paraSpaceBefore: idx === 0 ? 0 : 6
        }
      });
    } else if (item.type === "bullet") {
      richText.push({
        text: item.text,
        options: {
          bold: false, fontSize: 22, fontFace: FONT, color: BLACK,
          bullet: { type: "bullet", code: "2022" },
          indentLevel: 0, breakLine: !isLast,
          paraSpaceBefore: 2
        }
      });
    } else if (item.type === "ref") {
      richText.push({
        text: item.text,
        options: {
          bold: false, fontSize: 18, fontFace: FONT, color: BLACK,
          bullet: false, breakLine: !isLast,
          paraSpaceBefore: 3
        }
      });
    } else if (item.type === "plain") {
      richText.push({
        text: item.text,
        options: {
          bold: false, fontSize: 22, fontFace: FONT, color: BLACK,
          bullet: false, breakLine: !isLast,
          paraSpaceBefore: 3
        }
      });
    }
  });

  slide.addText(richText, {
    x: 0.4, y: 1.05, w: 9.2, h: 4.4,
    fontFace: FONT, fontSize: 22, color: BLACK,
    valign: "top", margin: [4, 0, 0, 0]
  });

  return slide;
}

// ─────────────────────────────────────────────────────────────
// SLIDE 1 – TITLE SLIDE
// ─────────────────────────────────────────────────────────────
{
  const slide = pres.addSlide();
  slide.background = { color: WHITE };

  slide.addText("A STUDY OF RED CELL DISTRIBUTION WIDTH AS A PROGNOSTIC MARKER IN PATIENTS WITH HEART FAILURE", {
    x: 0.5, y: 0.6, w: 9.0, h: 1.8,
    fontFace: FONT, fontSize: 30, bold: true, color: BLACK,
    align: "center", valign: "middle"
  });

  slide.addShape(pres.ShapeType.line, {
    x: 1.5, y: 2.55, w: 7.0, h: 0,
    line: { color: BLACK, width: 1 }
  });

  const details = [
    { text: "Principal Investigator:", options: { bold: true, fontSize: 22, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "Dr. Ayushi Agrawal", options: { bold: false, fontSize: 22, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "2nd Year Resident, General Medicine", options: { bold: false, fontSize: 20, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "\u2003", options: { fontSize: 8, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "PG Guide: ", options: { bold: true, fontSize: 22, fontFace: FONT, color: BLACK, breakLine: false } },
    { text: "Dr. P.N. Palat (Head of Unit)", options: { bold: false, fontSize: 22, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "Co-Guides: ", options: { bold: true, fontSize: 22, fontFace: FONT, color: BLACK, breakLine: false } },
    { text: "Dr. Rajkamal Chaudhary (Associate Professor),  Dr. Dhwani Shah (Assistant Professor)", options: { bold: false, fontSize: 22, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "\u2003", options: { fontSize: 8, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "Department of General Medicine", options: { bold: false, fontSize: 20, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "Smt. NHL Municipal Medical College, Ahmedabad", options: { bold: false, fontSize: 20, fontFace: FONT, color: BLACK, breakLine: false } },
  ];

  slide.addText(details, {
    x: 0.5, y: 2.65, w: 9.0, h: 2.7,
    fontFace: FONT, fontSize: 22, color: BLACK,
    align: "center", valign: "top"
  });
}

// ─────────────────────────────────────────────────────────────
// SLIDE 2 – INTRODUCTION (Background & Rationale)
// ─────────────────────────────────────────────────────────────
addContentSlide("Introduction", [
  { type: "subheading", text: "Background & Rationale" },
  { type: "bullet", text: "Heart failure (HF) is a clinical syndrome characterized by structural and/or functional cardiac abnormalities impairing ventricular filling or blood ejection, resulting in reduced cardiac output and/or elevated intracardiac pressures." },
  { type: "bullet", text: "Diagnosis requires elevated natriuretic peptides (BNP/NT-proBNP) and/or objective evidence of cardiogenic congestion." },
  { type: "bullet", text: "HF disproportionately affects India: younger age at onset, high prevalence of rheumatic heart disease, rapidly rising diabetes burden (15.7% age-standardized prevalence; projected 151% increase by 2030)." },
  { type: "bullet", text: "Red Cell Distribution Width (RDW), a routine CBC parameter, has emerged as a potential prognostic biomarker in cardiovascular disease." },
  { type: "bullet", text: "Elevated RDW reflects anisocytosis and may indicate chronic inflammation, iron dysregulation, nutritional deficiencies, or bone marrow dysfunction in HF." },
  { type: "bullet", text: "Simple, cost-effective biomarkers like RDW remain underutilized in routine practice despite their promise for risk stratification." },
]);

// ─────────────────────────────────────────────────────────────
// SLIDE 3 – INTRODUCTION (Research Question & Hypothesis)
// ─────────────────────────────────────────────────────────────
addContentSlide("Introduction (contd.)", [
  { type: "subheading", text: "Research Question" },
  { type: "bullet", text: "Can RDW serve as a simple, cost-effective prognostic marker for risk stratification and prediction of adverse outcomes in Indian patients with heart failure?" },
  { type: "subheading", text: "Hypothesis" },
  { type: "bullet", text: "Null Hypothesis (H\u2080): RDW levels do not significantly predict disease severity or adverse clinical outcomes in patients with heart failure." },
  { type: "bullet", text: "Alternative Hypothesis (H\u2081): Elevated RDW levels are significantly associated with worse disease severity and increased risk of adverse outcomes (readmissions/mortality) in heart failure patients." },
  { type: "subheading", text: "Study Rationale" },
  { type: "bullet", text: "Evaluating RDW utility will contribute to improved, personalized management approaches and healthcare delivery efficiency tailored to Indian HF populations." },
]);

// ─────────────────────────────────────────────────────────────
// SLIDE 4 – AIMS & OBJECTIVES
// ─────────────────────────────────────────────────────────────
addContentSlide("Aims & Objectives", [
  { type: "subheading", text: "Aim" },
  { type: "bullet", text: "To evaluate the role of Red Cell Distribution Width (RDW) as a prognostic marker in patients with heart failure." },
  { type: "subheading", text: "Primary Objective" },
  { type: "bullet", text: "To measure RDW levels in patients diagnosed with heart failure." },
  { type: "subheading", text: "Secondary Objectives" },
  { type: "bullet", text: "To assess the association between RDW levels and clinical outcomes in patients with heart failure." },
  { type: "bullet", text: "To determine the prognostic value of RDW in predicting disease severity and adverse outcomes in heart failure patients." },
]);

// ─────────────────────────────────────────────────────────────
// SLIDE 5 – METHODOLOGY: Study Design, Setting & Population
// ─────────────────────────────────────────────────────────────
addContentSlide("Methodology – Study Design & Setting", [
  { type: "subheading", text: "Study Design" },
  { type: "bullet", text: "Prospective observational study." },
  { type: "subheading", text: "Study Duration" },
  { type: "bullet", text: "1 year from the date of IRB approval." },
  { type: "subheading", text: "Study Center" },
  { type: "bullet", text: "Tertiary Care Hospital (Smt. NHL Municipal Medical College, Ahmedabad)." },
  { type: "subheading", text: "Study Population" },
  { type: "bullet", text: "Adult patients (age >18 years) diagnosed with heart failure based on standard clinical and echocardiographic criteria." },
  { type: "subheading", text: "Sample Size" },
  { type: "bullet", text: "Patients will be enrolled according to study duration (consecutive enrollment)." },
  { type: "subheading", text: "Outcome Measures" },
  { type: "bullet", text: "Disease severity, hospital readmissions, and/or mortality during the follow-up period." },
]);

// ─────────────────────────────────────────────────────────────
// SLIDE 6 – METHODOLOGY: Inclusion & Exclusion Criteria
// ─────────────────────────────────────────────────────────────
addContentSlide("Methodology – Inclusion & Exclusion Criteria", [
  { type: "subheading", text: "Inclusion Criteria" },
  { type: "bullet", text: "Adult patients aged \u226518 years." },
  { type: "bullet", text: "Diagnosed with heart failure based on standard clinical, laboratory, and echocardiographic criteria." },
  { type: "bullet", text: "Willing to provide written informed consent." },
  { type: "bullet", text: "Undergoing routine laboratory investigations including CBC at time of enrollment." },
  { type: "subheading", text: "Exclusion Criteria" },
  { type: "bullet", text: "Acute or chronic hematological disorders affecting RBC indices (e.g., hemolytic anemia, thalassemia)." },
  { type: "bullet", text: "Hemoglobin <9 g/dL at time of enrollment." },
  { type: "bullet", text: "Recent blood transfusion within last 3 months." },
  { type: "bullet", text: "Active infection, inflammatory disease, malignancy, chronic liver disease, or end-stage renal disease." },
  { type: "bullet", text: "Pregnant or lactating women." },
  { type: "bullet", text: "Patients unwilling or unable to provide informed consent." },
]);

// ─────────────────────────────────────────────────────────────
// SLIDE 7 – METHODOLOGY: Study Procedures & Data Analysis
// ─────────────────────────────────────────────────────────────
addContentSlide("Methodology – Study Procedures & Data Analysis", [
  { type: "subheading", text: "Study Procedures" },
  { type: "bullet", text: "Baseline demographic, clinical, and laboratory data including RDW (from routine CBC) collected at enrollment." },
  { type: "bullet", text: "Patients followed prospectively for predefined clinical outcomes." },
  { type: "subheading", text: "Data Analysis" },
  { type: "bullet", text: "Appropriate statistical tests used to assess association and prognostic value of RDW." },
  { type: "bullet", text: "Descriptive statistics: mean, SD, frequency, percentage." },
  { type: "bullet", text: "Inferential statistics: Chi-square test, Student t-test, ANOVA, ROC curve analysis (as applicable)." },
  { type: "bullet", text: "Level of significance: p < 0.05." },
]);

// ─────────────────────────────────────────────────────────────
// SLIDE 8 – ETHICAL CONSIDERATIONS
// ─────────────────────────────────────────────────────────────
addContentSlide("Ethical Considerations", [
  { type: "subheading", text: "Informed Consent Process" },
  { type: "bullet", text: "Written informed consent obtained from all participants." },
  { type: "bullet", text: "ICF available in English, Hindi, and Gujarati." },
  { type: "bullet", text: "Participation is voluntary; participants may withdraw at any time without affecting their standard treatment." },
  { type: "subheading", text: "Confidentiality Measures" },
  { type: "bullet", text: "Patient data anonymised; accessible only to the principal investigator and team." },
  { type: "bullet", text: "No personal identifiers disclosed in publications." },
  { type: "subheading", text: "Risk-Benefit Assessment" },
  { type: "bullet", text: "Minimal risk: all investigations are part of routine clinical care; no additional invasive procedures." },
  { type: "bullet", text: "Benefit: RDW as a cost-effective prognostic marker may improve risk stratification and management of future HF patients." },
  { type: "bullet", text: "Anticipated benefits outweigh the risks." },
]);

// ─────────────────────────────────────────────────────────────
// SLIDE 9 – PROFORMA / CASE RECORD FORM
// ─────────────────────────────────────────────────────────────
addContentSlide("Proforma / Case Record Form", [
  { type: "subheading", text: "Patient Identification & Demographics" },
  { type: "bullet", text: "Patient ID (code only)  |  Age  |  Gender" },
  { type: "subheading", text: "Clinical History" },
  { type: "bullet", text: "Presenting complaints: dyspnea, pedal oedema, chest pain, palpitation, orthopnea, PND, cough, fatigue, syncope." },
  { type: "bullet", text: "Known risk factors: HTN, DM, hypothyroidism, anemia, OSA, CAD, CKD, COPD, dyslipidemia." },
  { type: "bullet", text: "Addiction history, family history of CVD/HTN/DM." },
  { type: "subheading", text: "Examination & Investigations" },
  { type: "bullet", text: "General exam: BMI, vitals, pallor, clubbing, cyanosis, pedal edema, JVP, crackles, S3 gallop." },
  { type: "bullet", text: "Investigations: ECG, CXR, Echo, CBC (RDW), NT-proBNP, Troponin I, RFTs, USG abdomen." },
  { type: "subheading", text: "Outcome Assessment" },
  { type: "bullet", text: "NYHA functional classification  |  Prior hospitalizations  |  Clinical outcome at follow-up." },
]);

// ─────────────────────────────────────────────────────────────
// SLIDE 10 – INFORMED CONSENT FORM (English)
// ─────────────────────────────────────────────────────────────
addContentSlide("Informed Consent Form – English", [
  { type: "plain", text: "Study Title:  \"A Study of Red Cell Distribution Width as a Prognostic Marker in Patients with Heart Failure\"" },
  { type: "bullet", text: "I understand that collected data will be kept confidential and accessible to investigators only." },
  { type: "bullet", text: "This study will NOT affect my regular standard treatment as decided by the treating physician." },
  { type: "bullet", text: "Participation is voluntary. I may withdraw consent at any time; no compensation or penalty will apply." },
  { type: "bullet", text: "I hereby give my written informed consent to be included in the study." },
  { type: "plain", text: "" },
  { type: "plain", text: "Patient / Representative Signature / Thumbprint: ___________________" },
  { type: "plain", text: "Investigator's Signature: ___________________       Date: ___________" },
]);

// ─────────────────────────────────────────────────────────────
// SLIDE 11 – INFORMED CONSENT FORM (Hindi & Gujarati – note)
// ─────────────────────────────────────────────────────────────
{
  const slide = pres.addSlide();
  slide.background = { color: WHITE };

  slide.addText("Informed Consent Form – Hindi & Gujarati", {
    x: 0.4, y: 0.2, w: 9.2, h: 0.65,
    fontFace: FONT, fontSize: 28, bold: true, color: BLACK,
    align: "left", valign: "middle", margin: 0
  });
  slide.addShape(pres.ShapeType.line, {
    x: 0.4, y: 0.95, w: 9.2, h: 0,
    line: { color: BLACK, width: 1 }
  });

  const hindiText = [
    { text: "Hindi (सूचित सहमति पत्र)", options: { bold: true, fontSize: 22, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "\u2022  \u0939\u0943\u0926\u092F \u0935\u093F\u092B\u0932\u0924\u093E \u0915\u0947 \u092E\u0930\u0940\u091C\u093C\u094B\u0902 \u092E\u0947\u0902 \u0930\u094B\u0917 \u0915\u0947 \u092A\u0942\u0930\u094D\u0935 \u0905\u0928\u0941\u092E\u093E\u0928 \u0915\u0947 \u0938\u0902\u0915\u0947\u0924\u0915 \u0915\u0947 \u0924\u094C\u0930 \u092A\u0930 \u0932\u093E\u0932 \u0930\u0915\u094D\u0924 \u0915\u094B\u0936\u093F\u0915\u093E \u0935\u093F\u0924\u0930\u0923 \u091A\u094C\u0921\u093C\u093E\u0908 \u0915\u093E \u0905\u0927\u094D\u092F\u092F\u0928", options: { bold: false, fontSize: 20, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "\u2022  \u091C\u093E\u0928\u0915\u093E\u0930\u0940 \u0917\u094B\u092A\u0928\u0940\u092F \u0930\u0916\u0940 \u091C\u093E\u090F\u0917\u0940 \u0964 \u092D\u093E\u0917\u0940\u0926\u093E\u0930\u0940 \u0938\u094D\u0935\u0948\u091A\u094D\u091B\u093F\u0915 \u0939\u0948\u0964 \u0915\u093F\u0938\u0940 \u092D\u0940 \u0938\u092E\u092F \u0938\u0939\u092E\u0924\u093F \u0935\u093E\u092A\u0938 \u0932\u0947 \u0938\u0915\u0924\u0947 \u0939\u0948\u0902\u0964", options: { bold: false, fontSize: 20, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: " ", options: { fontSize: 10, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "Gujarati (માહિતીપૂર્ણ સંમતિ પત્રક)", options: { bold: true, fontSize: 22, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "\u2022  \u0AB9\u0AC3\u0AA6\u0AAF \u0AA8\u0ABF\u0AB7\u0ACD\u0AAB\u0AB3\u0AA4\u0ABE \u0AA7\u0AB0\u0ABE\u0AB5\u0AA4\u0ABE \u0AA6\u0AA6\u0AC0\u0A93\u0AAE\u0ABE\u0A82 \u0AAA\u0BC2\u0AB0\u0ACD\u0AB5 \u0A85\u0AA8\u0AC1\u0AAE\u0ABE\u0AA8 \u0AAE\u0ABE\u0AB0\u0ACD\u0A95\u0AB0 \u0AA4\u0AB0\u0AC0\u0A95\u0AC7 \u0AB0\u0AC7\u0AA1 \u0AB8\u0AC7\u0AB2 \u0AA1\u0ABF\u0AB8\u0ACD\u0A9F\u0ACD\u0AB0\u0ABF\u0AAC\u0ACD\u0AAF\u0AC1\u0AB6\u0AA8 \u0AB5\u0ABF\u0AA1\u0ACD\u0AA5\u0AA8\u0ACB \u0A85\u0AAD\u0ACD\u0AAF\u0ABE\u0AB8", options: { bold: false, fontSize: 20, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "\u2022  \u0AAE\u0ABE\u0AB9\u0ABF\u0AA4\u0AC0 \u0A97\u0ACB\u0AAA\u0AA8\u0AC0\u0AAF \u0AB0\u0ABE\u0B96\u0AB5\u0ABE\u0AAE\u0ABE\u0A82 \u0A86\u0AB5\u0AB6\u0AC7\u0964 \u0AAD\u0ABE\u0A97\u0AC0\u0AA6\u0ABE\u0AB0\u0AC0 \u0AB8\u0ACD\u0AB5\u0AC8\u0A9A\u0ACD\u0AB5\u0ABF\u0A95 \u0A9B\u0AC7\u0964 \u0A95\u0ACB\u0A88\u0AAA\u0AA3 \u0AB8\u0AAE\u0AAF\u0AC7 \u0AB8\u0A82\u0AAE\u0AA4\u0ABF \u0AAA\u0ABE\u0A9B\u0AC0 \u0B96\u0AC7\u0A82\u0A9A\u0AC0 \u0AB6\u0A95\u0ABE\u0AAF \u0A9B\u0AC7\u0964", options: { bold: false, fontSize: 20, fontFace: FONT, color: BLACK, breakLine: false } },
  ];

  slide.addText(hindiText, {
    x: 0.4, y: 1.05, w: 9.2, h: 4.4,
    fontFace: FONT, color: BLACK, valign: "top", margin: [4, 0, 0, 0]
  });
}

// ─────────────────────────────────────────────────────────────
// SLIDE 12 – REFERENCES
// ─────────────────────────────────────────────────────────────
addContentSlide("References (Vancouver Style)", [
  { type: "ref", text: "1. Felker GM, Allen LA, Pocock SJ, et al. Red cell distribution width as a novel prognostic marker in heart failure: data from the CHARM Program and the Duke Databank. J Am Coll Cardiol. 2007;50(1):40-7." },
  { type: "ref", text: "2. Tonelli M, Sacks F, Arnold M, et al. Relation between red blood cell distribution width and cardiovascular event rate in people with coronary disease. Circulation. 2008;117(2):163-8." },
  { type: "ref", text: "3. van Kimmenade RRJ, Mohammed AA, Uthamalingam S, et al. Red blood cell distribution width and 1-year mortality in acute heart failure. Eur J Heart Fail. 2010;12(2):129-36." },
  { type: "ref", text: "4. Ani C, Ovbiagele B. Elevated red blood cell distribution width predicts mortality in persons with known stroke. J Neurol Sci. 2009;277(1-2):103-8." },
  { type: "ref", text: "5. Allen LA, Felker GM, Mehra MR, et al. Validation and potential mechanisms of red cell distribution width as a prognostic marker in heart failure. J Card Fail. 2010;16(3):230-8." },
  { type: "ref", text: "6. Rudresh MG, Vivek KU. Relationship between red cell distribution width and heart failure. Int J Med Res Rev. 2016;4(2)." },
  { type: "ref", text: "7. Kumar V, Ramamoorthi K, Shridhar M. Red cell distribution width as a prognostic marker for patients with heart failure. Int J Acad Med. 2024;10(4):217-223." },
]);

// Write file
pres.writeFile({ fileName: "/home/daytona/workspace/ayushi-irb/Ayushi_IRB_NHLIRB.pptx" })
  .then(() => console.log("PPTX written successfully"))
  .catch(e => { console.error("Error:", e); process.exit(1); });

cd /home/daytona/workspace/ayushi-irb && node build.js 2>&1

ls -lh /home/daytona/workspace/ayushi-irb/Ayushi_IRB_NHLIRB.pptx

ls -lh /home/daytona/workspace/ayushi-irb/ && echo "---" && ls -lh /home/daytona…

python /home/daytona/skills/pptx/scripts/thumbnail.py /home/daytona/workspace/ay…

find /home/daytona -name "thumbnails.jpg" 2>/dev/null; find /home/daytona/skills…

~/ayushi-irb/build_v2.js

const pptxgen = require("pptxgenjs");

const pres = new pptxgen();
pres.layout = "LAYOUT_16x9";
pres.title = "A Study of Red Cell Distribution Width as a Prognostic Marker in Patients with Heart Failure";

const WHITE  = "FFFFFF";
const BLACK  = "000000";
const FONT   = "Calibri";

// Slide dimensions: 10" wide x 5.625" tall
// Title bar:  y=0.15, h=0.70  → bottom edge at 0.85"
// Separator:  y=0.88
// Body box:   y=0.95, h=4.55  → bottom edge at 5.50"  (leaves 0.125" margin)
// At 22pt body, line height ~0.35". Subheading ~0.38".
// Safe = ~11 visual lines per slide.

// ── helpers ────────────────────────────────────────────────────
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function makeSlide(title, items) {
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  addBody(slide, items);
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}

// ═══════════════════════════════════════════════════════════════
// SLIDE 1 – TITLE
// ═══════════════════════════════════════════════════════════════
{
  const slide = pres.addSlide();
  slide.background = { color: WHITE };

  // Institution header band
  slide.addShape(pres.ShapeType.rect, {
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  slide.addText("Smt. NHL Municipal Medical College, Ahmedabad", {
    x: 0, y: 0, w: 10, h: 0.6,
    fontFace: FONT, fontSize: 16, bold: false, color: WHITE,
    align: "center", valign: "middle"
  });

  // Study title
  slide.addText("A STUDY OF RED CELL DISTRIBUTION WIDTH AS A PROGNOSTIC MARKER IN PATIENTS WITH HEART FAILURE", {
    x: 0.6, y: 0.75, w: 8.8, h: 2.0,
    fontFace: FONT, fontSize: 30, bold: true, color: BLACK,
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    { text: "Principal Investigator: ", options: { bold: true, fontSize: 20, fontFace: FONT, color: BLACK } },
    { text: "Dr. Ayushi Agrawal", options: { bold: false, fontSize: 20, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "2nd Year Resident, Department of General Medicine", options: { bold: false, fontSize: 18, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: " ", options: { fontSize: 8, fontFace: FONT, color: WHITE, breakLine: true } },
    { text: "PG Guide: ", options: { bold: true, fontSize: 20, fontFace: FONT, color: BLACK } },
    { text: "Dr. P.N. Palat (Head of Unit)", options: { bold: false, fontSize: 20, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "Co-Guide: ", options: { bold: true, fontSize: 20, fontFace: FONT, color: BLACK } },
    { text: "Dr. Rajkamal Chaudhary (Associate Professor)", options: { bold: false, fontSize: 20, fontFace: FONT, color: BLACK, breakLine: true } },
    { text: "              ", options: { bold: true, fontSize: 20, fontFace: FONT, color: WHITE } },
    { text: "Dr. Dhwani Shah (Assistant Professor)", options: { bold: false, fontSize: 20, fontFace: FONT, color: BLACK, breakLine: false } },
  ];
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}

// ═══════════════════════════════════════════════════════════════
// SLIDE 2 – INTRODUCTION (Background & Rationale)
// ═══════════════════════════════════════════════════════════════
makeSlide("Introduction – Background & Rationale", [
  { type: "bullet", text: "Heart failure (HF) is a clinical syndrome characterised by structural and/or functional cardiac abnormalities that impair ventricular filling or blood ejection." },
  { type: "bullet", text: "Results in reduced cardiac output and/or elevated intracardiac pressures; diagnosed by elevated BNP/NT-proBNP or objective evidence of cardiogenic congestion." },
  { type: "bullet", text: "HF disproportionately affects India: younger age at onset, high prevalence of rheumatic heart disease, rapidly rising diabetes burden (15.7% age-standardised prevalence; projected 151% increase by 2030)." },
  { type: "bullet", text: "Red Cell Distribution Width (RDW) — a routine CBC parameter — has emerged as a potential prognostic biomarker in cardiovascular disease." },
  { type: "bullet", text: "Elevated RDW reflects anisocytosis, indicating chronic inflammation, iron dysregulation, nutritional deficiencies, or bone marrow dysfunction in HF." },
  { type: "bullet", text: "Simple, cost-effective biomarkers like RDW remain underutilised in routine practice despite their promise for risk stratification." },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 3 – INTRODUCTION (Research Question & Hypothesis)
// ═══════════════════════════════════════════════════════════════
makeSlide("Introduction – Research Question & Hypothesis", [
  { type: "subheading", text: "Research Question" },
  { type: "bullet", text: "Can RDW serve as a simple, cost-effective prognostic marker for risk stratification and prediction of adverse outcomes in Indian patients with heart failure?" },
  { type: "spacer" },
  { type: "subheading", text: "Hypothesis" },
  { type: "bullet", text: "Null (H\u2080): RDW levels do not significantly predict disease severity or adverse clinical outcomes in HF patients." },
  { type: "bullet", text: "Alternative (H\u2081): Elevated RDW is significantly associated with worse disease severity and increased risk of readmissions/mortality in HF patients." },
  { type: "spacer" },
  { type: "subheading", text: "Rationale" },
  { type: "bullet", text: "Evaluating RDW utility will contribute to improved personalised management approaches tailored to Indian HF populations in resource-constrained settings." },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 4 – AIMS & OBJECTIVES
// ═══════════════════════════════════════════════════════════════
makeSlide("Aims & Objectives", [
  { type: "subheading", text: "Aim" },
  { type: "bullet", text: "To evaluate the role of Red Cell Distribution Width (RDW) as a prognostic marker in patients with heart failure." },
  { type: "spacer" },
  { type: "subheading", text: "Primary Objective" },
  { type: "bullet", text: "To measure RDW levels in patients diagnosed with heart failure." },
  { type: "spacer" },
  { type: "subheading", text: "Secondary Objectives" },
  { type: "bullet", text: "To assess the association between RDW levels and clinical outcomes in patients with heart failure." },
  { type: "bullet", text: "To determine the prognostic value of RDW in predicting disease severity and adverse outcomes in heart failure patients." },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 5 – METHODOLOGY: Study Design & Setting
// ═══════════════════════════════════════════════════════════════
makeSlide("Methodology – Study Design & Setting", [
  { type: "subheading", text: "Study Design" },
  { type: "bullet", text: "Prospective observational study." },
  { type: "spacer" },
  { type: "subheading", text: "Study Duration" },
  { type: "bullet", text: "1 year from the date of IRB approval." },
  { type: "spacer" },
  { type: "subheading", text: "Study Centre" },
  { type: "bullet", text: "Tertiary Care Hospital — Smt. NHL Municipal Medical College, Ahmedabad." },
  { type: "spacer" },
  { type: "subheading", text: "Study Population" },
  { type: "bullet", text: "Adult patients (age > 18 years) diagnosed with heart failure based on standard clinical and echocardiographic criteria." },
  { type: "spacer" },
  { type: "subheading", text: "Sample Size & Sampling" },
  { type: "bullet", text: "Consecutive enrollment of all eligible patients over the study duration." },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 6 – METHODOLOGY: Inclusion Criteria
// ═══════════════════════════════════════════════════════════════
makeSlide("Methodology – Inclusion Criteria", [
  { type: "bullet", text: "Adult patients aged \u2265 18 years." },
  { type: "bullet", text: "Diagnosed with heart failure based on standard clinical, laboratory, and echocardiographic criteria." },
  { type: "bullet", text: "Willing to provide written informed consent." },
  { type: "bullet", text: "Undergoing routine laboratory investigations including complete blood count (CBC) at time of enrollment." },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 7 – METHODOLOGY: Exclusion Criteria
// ═══════════════════════════════════════════════════════════════
makeSlide("Methodology – Exclusion Criteria", [
  { type: "bullet", text: "Acute or chronic haematological disorders affecting red blood cell indices (e.g., haemolytic anaemia, thalassaemia)." },
  { type: "bullet", text: "Haemoglobin < 9 g/dL at time of enrollment." },
  { type: "bullet", text: "Recent blood transfusion within the last 3 months." },
  { type: "bullet", text: "Active infection, inflammatory disease, or malignancy at time of enrollment." },
  { type: "bullet", text: "Chronic liver disease or end-stage renal disease." },
  { type: "bullet", text: "Pregnant or lactating women." },
  { type: "bullet", text: "Patients unwilling or unable to provide informed consent." },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 8 – METHODOLOGY: Study Procedures & Outcome Measures
// ═══════════════════════════════════════════════════════════════
makeSlide("Methodology – Study Procedures & Outcome Measures", [
  { type: "subheading", text: "Data Collection" },
  { type: "bullet", text: "Baseline demographic, clinical, and laboratory data collected at enrollment." },
  { type: "bullet", text: "RDW obtained from routine complete blood count (CBC)." },
  { type: "bullet", text: "Patients followed prospectively for predefined clinical outcomes." },
  { type: "spacer" },
  { type: "subheading", text: "Outcome Measures" },
  { type: "bullet", text: "Disease severity (NYHA functional class)." },
  { type: "bullet", text: "Hospital readmissions during the follow-up period." },
  { type: "bullet", text: "Mortality during the follow-up period." },
  { type: "spacer" },
  { type: "subheading", text: "Statistical Analysis" },
  { type: "bullet", text: "Descriptive statistics: mean, SD, frequency, percentage." },
  { type: "bullet", text: "Inferential statistics: Chi-square, Student t-test, ANOVA, ROC curve analysis (p < 0.05)." },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 9 – ETHICAL CONSIDERATIONS
// ═══════════════════════════════════════════════════════════════
makeSlide("Ethical Considerations", [
  { type: "subheading", text: "Informed Consent Process" },
  { type: "bullet", text: "Written informed consent obtained from all participants prior to enrollment." },
  { type: "bullet", text: "ICF available in English, Hindi, and Gujarati." },
  { type: "bullet", text: "Participation is voluntary; withdrawal at any time does not affect standard treatment." },
  { type: "spacer" },
  { type: "subheading", text: "Confidentiality" },
  { type: "bullet", text: "Data anonymised; accessible only to the principal investigator and team." },
  { type: "bullet", text: "No personal identifiers disclosed in publications or presentations." },
  { type: "spacer" },
  { type: "subheading", text: "Risk–Benefit Assessment" },
  { type: "bullet", text: "Minimal risk: all investigations are part of routine clinical care; no additional invasive procedures." },
  { type: "bullet", text: "Potential benefit: RDW as a cost-effective prognostic marker may improve risk stratification and management of future HF patients." },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 10 – DATA ANALYSIS
// ═══════════════════════════════════════════════════════════════
makeSlide("Data Analysis", [
  { type: "subheading", text: "Statistical Methods" },
  { type: "bullet", text: "Data entry: Microsoft Excel." },
  { type: "bullet", text: "Statistical software: SPSS v26.0 (or equivalent)." },
  { type: "spacer" },
  { type: "subheading", text: "Descriptive Statistics" },
  { type: "bullet", text: "Continuous variables: Mean \u00b1 Standard Deviation." },
  { type: "bullet", text: "Categorical variables: Frequency and Percentage." },
  { type: "spacer" },
  { type: "subheading", text: "Inferential Statistics" },
  { type: "bullet", text: "Chi-square test for categorical associations." },
  { type: "bullet", text: "Student t-test / Mann-Whitney U for continuous variables." },
  { type: "bullet", text: "ROC curve analysis for prognostic cut-off of RDW." },
  { type: "bullet", text: "Level of significance: p < 0.05." },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 11 – PROFORMA: Patient Info & Clinical History
// ═══════════════════════════════════════════════════════════════
makeSlide("Proforma / Case Record Form – Part 1", [
  { type: "subheading", text: "Patient Identification & Demographics" },
  { type: "bullet", text: "Patient ID (code only)  |  Age (years)  |  Gender" },
  { type: "spacer" },
  { type: "subheading", text: "Presenting Complaints" },
  { type: "bullet", text: "Dyspnoea on exertion, pedal oedema, chest pain, palpitation." },
  { type: "bullet", text: "Orthopnoea, paroxysmal nocturnal dyspnoea (PND), cough, fatigue, syncope." },
  { type: "spacer" },
  { type: "subheading", text: "Known Risk Factors" },
  { type: "bullet", text: "Hypertension, diabetes mellitus, hypothyroidism, anaemia, OSA/obesity." },
  { type: "bullet", text: "Coronary artery disease, chronic kidney disease, COPD, dyslipidaemia." },
  { type: "spacer" },
  { type: "subheading", text: "Other History" },
  { type: "bullet", text: "Addiction history (smoking, alcohol, tobacco)." },
  { type: "bullet", text: "Family history: CVD, hypertension, diabetes mellitus." },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 12 – PROFORMA: Examination & Investigations
// ═══════════════════════════════════════════════════════════════
makeSlide("Proforma / Case Record Form – Part 2", [
  { type: "subheading", text: "General Examination" },
  { type: "bullet", text: "Weight, height, BMI, vitals (BP, HR, RR, SpO\u2082)." },
  { type: "bullet", text: "Pallor, clubbing, cyanosis, pedal oedema, JVP, pulmonary crackles, S3 gallop, hepatojugular reflux." },
  { type: "spacer" },
  { type: "subheading", text: "Systemic Examination" },
  { type: "bullet", text: "CVS, Respiratory system, other systems." },
  { type: "spacer" },
  { type: "subheading", text: "Diagnostic Investigations" },
  { type: "bullet", text: "ECG, chest X-ray, echocardiography, USG abdomen." },
  { type: "bullet", text: "CBC (RDW), NT-proBNP, Troponin I, renal function tests, others." },
  { type: "spacer" },
  { type: "subheading", text: "Outcome Assessment" },
  { type: "bullet", text: "NYHA functional classification  |  Prior hospitalisation history  |  Clinical outcome at follow-up." },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 13 – ICF (English)
// ═══════════════════════════════════════════════════════════════
makeSlide("Informed Consent Form – English", [
  { type: "plain", text: "Study: \"A Study of Red Cell Distribution Width as a Prognostic Marker in Patients with Heart Failure\"" },
  { type: "spacer" },
  { type: "bullet", text: "I have been explained the purpose and procedures of the above study." },
  { type: "bullet", text: "I understand the data collected will be kept confidential and accessible to investigators only." },
  { type: "bullet", text: "This study will NOT affect my regular standard treatment as decided by the treating physician." },
  { type: "bullet", text: "My participation is voluntary. I may withdraw consent at any time without penalty." },
  { type: "bullet", text: "I hereby give my written informed consent to be included in the study." },
  { type: "spacer" },
  { type: "plain", text: "Patient / Representative Signature / Thumbprint: ____________________" },
  { type: "plain", text: "Investigator's Signature: ____________________       Date: ____________" },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 14 – ICF (Hindi)
// ═══════════════════════════════════════════════════════════════
makeSlide("Informed Consent Form – Hindi (\u0938\u0942\u091A\u093F\u0924 \u0938\u0939\u092E\u0924\u093F \u092A\u0924\u094D\u0930)", [
  { type: "plain", text: "\u0905\u0927\u094D\u092F\u092F\u0928: \"\u0939\u0943\u0926\u092F \u0935\u093F\u092B\u0932\u0924\u093E \u0915\u0947 \u092E\u0930\u0940\u091C\u093C\u094B\u0902 \u092E\u0947\u0902 \u0930\u094B\u0917 \u0915\u0947 \u092A\u0942\u0930\u094D\u0935 \u0905\u0928\u0941\u092E\u093E\u0928 \u0915\u0947 \u0938\u0902\u0915\u0947\u0924\u0915 \u0915\u0947 \u0924\u094C\u0930 \u092A\u0930 RDW \u0915\u093E \u0905\u0927\u094D\u092F\u092F\u0928\"" },
  { type: "spacer" },
  { type: "bullet", text: "\u091C\u093E\u0928\u0915\u093E\u0930\u0940 \u0917\u094B\u092A\u0928\u0940\u092F \u0930\u0916\u0940 \u091C\u093E\u090F\u0917\u0940 \u0914\u0930 \u0915\u0947\u0935\u0932 \u0936\u094B\u0927\u0915\u0930\u094D\u0924\u093E\u0913\u0902 \u0915\u094B \u0909\u092A\u0932\u092C\u094D\u0927 \u0939\u094B\u0917\u0940\u0964" },
  { type: "bullet", text: "\u0907\u0938 \u0905\u0927\u094D\u092F\u092F\u0928 \u0938\u0947 \u092E\u0947\u0930\u0947 \u0928\u093F\u092F\u092E\u093F\u0924 \u092E\u093E\u0928\u0915 \u0909\u092A\u091A\u093E\u0930 \u092A\u0930 \u0915\u094B\u0908 \u092A\u094D\u0930\u092D\u093E\u0935 \u0928\u0939\u0940\u0902 \u092A\u0921\u093C\u0947\u0917\u093E\u0964" },
  { type: "bullet", text: "\u092D\u093E\u0917\u0940\u0926\u093E\u0930\u0940 \u0938\u094D\u0935\u0948\u091A\u094D\u091B\u093F\u0915 \u0939\u0948\u0964 \u092E\u0948\u0902 \u0915\u093F\u0938\u0940 \u092D\u0940 \u0938\u092E\u092F \u0938\u0939\u092E\u0924\u093F \u0935\u093E\u092A\u0938 \u0932\u0947 \u0938\u0915\u0924\u093E/\u0938\u0915\u0924\u0940 \u0939\u0942\u0901\u0964" },
  { type: "bullet", text: "\u092E\u0948\u0902 \u0907\u0938 \u0905\u0927\u094D\u092F\u092F\u0928 \u092E\u0947\u0902 \u092D\u093E\u0917 \u0932\u0947\u0928\u0947 \u0915\u0947 \u0932\u093F\u090F \u0905\u092A\u0928\u0940 \u0932\u093F\u0916\u093F\u0924 \u0938\u0942\u091A\u093F\u0924 \u0938\u0939\u092E\u0924\u093F \u0926\u0947\u0924\u093E/\u0926\u0947\u0924\u0940 \u0939\u0942\u0901\u0964" },
  { type: "spacer" },
  { type: "plain", text: "\u092E\u0930\u0940\u091C\u093C (\u092A\u094D\u0930\u0924\u093F\u0928\u093F\u0927\u093F) \u0915\u0947 \u0939\u0938\u094D\u0924\u093E\u0915\u094D\u0937\u0930 / \u0905\u0902\u0917\u0942\u0920\u0947 \u0915\u093E \u0928\u093F\u0936\u093E\u0928: ____________________" },
  { type: "plain", text: "\u0936\u094B\u0927\u0915\u0930\u094D\u0924\u093E \u0915\u0947 \u0939\u0938\u094D\u0924\u093E\u0915\u094D\u0937\u0930: ____________________       \u0926\u093F\u0928\u093E\u0902\u0915: ____________" },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 15 – ICF (Gujarati)
// ═══════════════════════════════════════════════════════════════
makeSlide("Informed Consent Form – Gujarati (\u0AAE\u0ABE\u0AB9\u0ABF\u0AA4\u0AC0\u092A\u0BC2\u0AB0\u094D\u0923 \u0938\u0902\u092E\u0AA4\u093F \u092A\u0AA4\u094D\u0930\u0A95)", [
  { type: "plain", text: "\u0A85\u0AAD\u0ACD\u0AAF\u0ABE\u0AB8: \"\u0AB9\u0AC3\u0AA6\u0AAF \u0AA8\u0ABF\u0AB7\u0ACD\u0AAB\u0AB3\u0AA4\u0ABE \u0AA7\u0AB0\u0ABE\u0AB5\u0AA4\u0ABE \u0AA6\u0AA6\u0AC0\u0A93\u0AAE\u0ABE\u0A82 RDW \u0AA8\u0ACB \u0AAA\u0BC2\u0AB0\u094D\u0AB5 \u0A85\u0AA8\u0AC1\u0AAE\u0ABE\u0AA8 \u0AAE\u0ABE\u0AB0\u0ACD\u0A95\u0AB0 \u0AA4\u0AB0\u0AC0\u0A95\u0AC7 \u0A85\u0AAD\u0ACD\u0AAF\u0ABE\u0AB8\"" },
  { type: "spacer" },
  { type: "bullet", text: "\u0A8F\u0A95\u0AA4\u094D\u0AB0\u093F\u0AA4 \u0A95\u0AB0\u0AC7\u0AB2 \u0AAE\u0ABE\u0AB9\u0ABF\u0AA4\u0AC0 \u0A97\u0ACB\u0AAA\u0AA8\u0AC0\u0AAF \u0AB0\u0ABE\u0B96\u0AB5\u0ABE\u0AAE\u0ABE\u0A82 \u0A86\u0AB5\u0AB6\u0AC7\u0964" },
  { type: "bullet", text: "\u0A86 \u0A85\u0AAD\u0ACD\u0AAF\u0ABE\u0AB8\u0AA5\u0AC0 \u0AAE\u0ABE\u0AB0\u0ABE \u0AA8\u0ABF\u0AAF\u0AAE\u0ABF\u0AA4 \u0AA4\u0AA5\u0ABE \u0AAE\u0ABE\u0AA8\u0A95 \u0A89\u0AAA\u091A\u0ABE\u0AB0 \u092A\u0AB0 \u0A85\u0AB8\u0AB0 \u0AA5\u0AB6\u0AC7 \u0AA8\u0AB9\u0AC0\u0A82\u0964" },
  { type: "bullet", text: "\u0AAD\u0ABE\u0A97\u0AC0\u0AA6\u0ABE\u0AB0\u0AC0 \u0AB8\u0ACD\u0AB5\u0AC8\u0A9A\u0ACD\u0AB5\u093F\u0A95 \u0A9B\u0AC7\u0964 \u0AB9\u0AC1\u0A82 \u0A95\u0ACB\u0A88\u092A\u0AA3 \u0AB8\u0AAE\u0AAF\u0AC7 \u0AB8\u0A82\u0AAE\u0AA4\u093F \u092A\u093E\u091B\u0AC0 \u0B96\u0AC7\u0A82\u091A\u0AC0 \u0AB6\u0A95\u0AC1\u0A82 \u091B\u0941\u0A82\u0964" },
  { type: "bullet", text: "\u0AB9\u0AC1\u0A82 \u0A86 \u0A85\u0AAD\u0ACD\u0AAF\u0ABE\u0AB8\u0AAE\u0ABE\u0A82 \u0AAD\u0ABE\u0A97 \u0AB2\u0AC7\u0AB5\u0ABE \u0AAE\u0ABE\u0A9F\u0AC7 \u0AAE\u0ABE\u0AB0\u0AC0 \u0AB2\u0AC7\u0B96\u093F\u0AA4 \u0AB8\u0BC2\u091A\u093F\u0AA4 \u0AB8\u0A82\u0AAE\u0AA4\u093F \u0A86\u092A\u0AC1\u0A82 \u091B\u0AC1\u0A82\u0964" },
  { type: "spacer" },
  { type: "plain", text: "\u0AA6\u0AA6\u0AC0 (\u092A\u094D\u0AB0\u0AA4\u093F\u0AA8\u093F\u0AA7\u093F) \u0AA8\u093E \u0AB9\u0AB8\u094D\u0AA4\u093E\u0B95\u094D\u0AB7\u0AB0: ____________________" },
  { type: "plain", text: "\u0AB8\u0A82\u0AB6\u094B\u0AA7\u0AA8\u0A95\u0AB0\u094D\u0AA4\u093E\u0AA8\u093E \u0AB9\u0AB8\u094D\u0AA4\u093E\u0B95\u094D\u0AB7\u0AB0: ____________________       \u0AA4\u093E\u0AB0\u0AC0\u0B96: ____________" },
]);

// ═══════════════════════════════════════════════════════════════
// SLIDE 16 – REFERENCES
// ═══════════════════════════════════════════════════════════════
makeSlide("References (Vancouver Style)", [
  { type: "ref", text: "1. Felker GM, Allen LA, Pocock SJ, et al. Red cell distribution width as a novel prognostic marker in heart failure: data from the CHARM Program and the Duke Databank. J Am Coll Cardiol. 2007;50(1):40-7." },
  { type: "ref", text: "2. Tonelli M, Sacks F, Arnold M, et al. Relation between red blood cell distribution width and cardiovascular event rate in people with coronary disease. Circulation. 2008;117(2):163-8." },
  { type: "ref", text: "3. van Kimmenade RRJ, Mohammed AA, Uthamalingam S, et al. Red blood cell distribution width and 1-year mortality in acute heart failure. Eur J Heart Fail. 2010;12(2):129-36." },
  { type: "ref", text: "4. Ani C, Ovbiagele B. Elevated red blood cell distribution width predicts mortality in persons with known stroke. J Neurol Sci. 2009;277(1-2):103-8." },
  { type: "ref", text: "5. Allen LA, Felker GM, Mehra MR, et al. Validation and potential mechanisms of red cell distribution width as a prognostic marker in heart failure. J Card Fail. 2010;16(3):230-8." },
  { type: "ref", text: "6. Rudresh MG, Vivek KU. Relationship between red cell distribution width and heart failure. Int J Med Res Rev. 2016;4(2)." },
  { type: "ref", text: "7. Kumar V, Ramamoorthi K, Shridhar M. Red cell distribution width as a prognostic marker for patients with heart failure. Int J Acad Med. 2024;10(4):217-223." },
]);

// ── Write ──────────────────────────────────────────────────────
pres.writeFile({ fileName: "/home/daytona/workspace/ayushi-irb/Ayushi_IRB_NHLIRB_v2.pptx" })
  .then(() => console.log("PPTX v2 written successfully"))
  .catch(e => { console.error("Error:", e); process.exit(1); });

cd /home/daytona/workspace/ayushi-irb && node build_v2.js 2>&1

ls -lh /home/daytona/workspace/ayushi-irb/Ayushi_IRB_NHLIRB_v2.pptx