teach me geriatric mood disorder especially depression and geriatric psychosis...20 marks question each..so explain all the aspects dont miss anything

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GERIATRIC DEPRESSION (20 Marks) covers:

  1. Introduction & significance - WHO burden data, underdiagnosis
  2. Epidemiology - prevalence figures (1-5% community; 40% chronic with partial remission)
  3. Risk factors - biological and psychosocial
  4. Clinical features - atypical presentation in elderly (somatic, anhedonia, cognitive), subtypes (psychotic, vascular, pseudodementia, minor)
  5. Neurobiology - vascular hypothesis, inflammation hypothesis (IL-6, TNF, CRP), HPA axis, monoamines, dementia link
  6. Comorbidities - cancer, dementia, Parkinson, cerebrovascular disease, suicide risk
  7. Assessment - GDS, PHQ-9, Cornell Scale, full evaluation checklist
  8. Treatment - pharmacotherapy (SSRIs, SNRIs, TCAs, newer agents with doses), ECT, psychotherapy (CBT, PST, IPT, Life Review), collaborative care model
  9. Course & prognosis - relapse rates, chronicity predictors, dementia conversion

GERIATRIC PSYCHOSIS (20 Marks) covers:

  1. Introduction & classification - EOS, LOS, VLOS, delusional disorder, dementia psychosis, psychotic depression, secondary causes
  2. Epidemiology - prevalence rates, sex ratios
  3. EOS vs LOS vs VLOS comparison table
  4. Etiology & pathophysiology - estrogen hypothesis, neurodevelopmental vs. neurodegenerative, dopamine dysregulation
  5. Clinical features - distinctive features of each type, partition delusions in VLOS
  6. Differential diagnosis table
  7. Role of sensory impairment - hearing loss, visual impairment as risk factors
  8. Assessment - full workup including MRI, EEG
  9. Treatment - non-pharmacological (first-line in dementia), antipsychotics (doses table: risperidone, quetiapine, olanzapine, aripiprazole, clozapine), pimavanserin, TD management, adjuncts
  10. Special issues - DLB neuroleptic sensitivity, delusional disorder adherence, withdrawal in elderly
  11. Summary comparison table
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