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National Leprosy Eradication Programme (NLEP)
Background & History
| Year | Event |
|---|
| 1955 | National Leprosy Control Programme (NLCP) launched — early detection & Dapsone monotherapy |
| 1983 | Restructured into NLEP after WHO recommended Multi-Drug Therapy (MDT); focus shifted from control → elimination |
| 1993–94 | Expanded to all districts with World Bank assistance |
| 2005 | National elimination achieved (prevalence < 1/10,000) — December 2005 |
| 2025 | Leprosy declared a Notifiable Disease; revised 3-drug MDT protocol implemented nationwide (April 1, 2025) |
NLEP is a centrally sponsored scheme under the National Health Mission (NHM), administered by the Directorate General of Health Services (DGHS), Ministry of Health & Family Welfare.
Mission
To provide quality leprosy services free of cost to all sections of the population through the integrated healthcare system, including care for disability after cure.
Objectives
- Reduce Prevalence Rate (PR) to < 1/10,000 at sub-national and district level
- Early detection and complete treatment of all new leprosy cases
- Household contact surveys through ASHAs for early detection and treatment completion
- Strengthen Disability Prevention and Medical Rehabilitation (DPMR) services
- IEC/BCC activities to improve self-reporting to PHCs and reduce stigma
- Zero disabilities among new child cases
- Zero stigma and discrimination against persons affected by leprosy
Programme Components
- Case Detection and Management — Active Case Detection Campaigns (ACDC), Focused Leprosy Campaigns (FLC), household contact tracing
- Disability Prevention and Medical Rehabilitation (DPMR) — reconstructive surgery, physiotherapy, self-care
- IEC/BCC (Behaviour Change Communication) — community awareness, reduction of stigma
- Human Resources and Capacity Building — training of healthcare providers, ASHA involvement
- Programme Management — monitoring, supervision, digital surveillance (Nikusth 2.0 platform)
Treatment Protocol (Revised April 1, 2025)
In alignment with WHO recommendations, a unified 3-drug MDT regimen is now used for both Paucibacillary (PB) and Multibacillary (MB) cases:
| Drug | Role |
|---|
| Rifampicin | Bactericidal — kills M. leprae rapidly |
| Dapsone | Bacteriostatic — prevents resistance |
| Clofazimine | Anti-inflammatory + bactericidal |
This replaces the older separate PB (2-drug, 6 months) and MB (3-drug, 12 months) regimens with a single unified protocol, enhancing operational uniformity.
Key Campaigns
- Leprosy Case Detection Campaign (LCDC) — mass active case finding
- Active Case Detection Campaign (ACDC) — door-to-door surveys by frontline workers
- Focused Leprosy Campaign (FLC) — targeted high-burden areas; triggered when ≥1 Grade 2 disability (G2D) case is reported
- ASWAMEDHAM (Kerala) — detects hidden/untreated cases in the community
Supporting Institutions
| Institute | Location |
|---|
| Central Leprosy Teaching & Research Institute (CLTRI) | Chengalpattu, Tamil Nadu |
| Regional Leprosy Training & Research Institute (RLTRI) | Raipur, Gauripur, Aska |
Indicators & Achievements (2014–15 to 2024–25)
| Indicator | 2014–15 | 2018–19 | 2024–25 |
|---|
| Prevalence Rate (per 10,000) | 0.69 | 0.62 | 0.57 |
| % Child Cases | 9.04% | 7.67% | 4.68% |
| Grade 2 Disability per million | 4.48 | 2.65 | 1.31 |
| Annual New Case Detection Rate (per 100,000) | 9.73 | 8.69 | 7.00 |
| Districts achieving elimination | 542 | — | 638/638 |
District-level elimination has been achieved nationwide as of 2024–25.
National Strategic Plan (NSP) & Roadmap 2023–2027
Vision: Leprosy-free India with zero infection and disease, zero disability, zero stigma and discrimination
Goal: Interrupt leprosy transmission in India by 2027
Five Pillars:
- Strengthen leadership, commitment & partnerships
- Accelerate case detection
- Provide comprehensive, quality leprosy services
- Reduce disability, stigma & discrimination
- Develop digital surveillance systems (Nikusth 2.0, integration with IHIP)
Aligned with WHO NTD Roadmap 2021–2030 and Global Leprosy Strategy 2021–2030.
Key Points for Exams
- NLEP launched: 1983 (NLCP was 1955)
- Elimination achieved at national level: December 2005
- Elimination definition: PR < 1/10,000 population
- MDT introduced: early 1980s (WHO recommendation)
- World Bank support: expanded to all districts by 1993–94
- From April 2025: unified 3-drug MDT for both PB and MB cases
- Leprosy declared Notifiable Disease in 2025
- Key frontline worker: ASHA (Accredited Social Health Activist)
- Digital platform: Nikusth 2.0