Explain Abortion neet pg lvl

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Abortion - NEET PG Complete Notes


1. DEFINITION

AuthorityDefinition
WHO / ClinicalExpulsion or extraction of an embryo/fetus weighing <500 g or before 20 weeks of gestation
Medical (India)Expulsion of products of conception before 28 weeks (viability)
Legal (India)Expulsion of products of conception from the uterus at any period prior to full term; law makes no distinction between abortion, miscarriage, and premature labor
NEET trick: Medical definition uses 28 weeks; WHO/international uses 20 weeks / <500 g.
Terminology by gestational age (legal):
  • Ovum - product of conception between 7-10 days
  • Embryo - after 10 days until end of 9th week
  • Fetus - after 9th week until birth

2. INCIDENCE

  • 10-15% of clinically recognized pregnancies end in spontaneous abortion
  • Using sensitive β-hCG assays, an additional ~20% of early pregnancies abort spontaneously (total ~30-40%)
  • ~75% of spontaneous abortions occur before 8 weeks
  • ~50% of abortions have chromosomal abnormalities (Robbins)

3. CLASSIFICATION

A. Forensic / Legal Classification

TypeDescription
NaturalSpontaneous or accidental, before 28 weeks
Artificial/Induced - JustifiableMTP Act permitted termination
Artificial/Induced - CriminalUnlawful termination without proper indication

B. Clinical Types (Most Important for NEET PG)

TypeCervical OsBleedingTissue PassedKey Feature
ThreatenedClosedMild-moderateNonePain mild; viable fetus on USG; manage conservatively
InevitableOpen/DilatedHeavyNoneSevere pain; cannot be saved
IncompleteOpenContinuousPartial (placenta retained)Most common complication = retention of placenta; needs evacuation
CompleteClosingReducingAll POC passedUSG shows empty uterus; manage conservatively
MissedClosedBrown dischargeNone (retained dead fetus >4 weeks)Uterus smaller than dates; POC converted to carneous/blood mole
SepticVariableVariableVariableFever + signs of infection + any stage of abortion
Recurrent (Habitual)---3 or more consecutive spontaneous abortions
NEET mnemonics:
  • Threatened = Closed os (the fetus is still "threatened" but not yet gone)
  • Inevitable = Open os (cannot be reversed)
  • Missed abortion = fetus dies, retained >4 weeks, uterus smaller than dates, brown discharge

4. ETIOLOGY OF SPONTANEOUS ABORTION

Fetal Causes (Most Common Overall)

  • Chromosomal abnormalities - present in ~50% of early abortions (aneuploidy, polyploidy, translocations)
  • More subtle genetic defects not detectable on routine karyotype

Maternal Causes

CategoryExamples
EndocrineLuteal phase defect, poorly controlled diabetes, thyroid disorders
Uterine anomaliesSubmucosal leiomyomas, polyps, uterine malformations (prevent/disrupt implantation)
ImmunologicalAntiphospholipid antibody syndrome, coagulopathies
InfectionsToxoplasma, Mycoplasma, Listeria, TORCH viruses, syphilis, HIV
Systemic diseaseHypertension, autoimmune disorders
EnvironmentalAnesthetic agents, heavy metals (lead), tobacco, X-rays
OtherAdvanced maternal age, prior poor obstetric history
Key fact: Ascending infections from the cervicovaginal vault are a common cause of second-trimester losses. (Robbins)

5. MECHANISM OF ABORTION

The process mirrors normal labor:
  1. Expulsion of whole ovum in one piece - early weeks; decidua vera + basalis separates and expels ovum entirely
  2. Expulsion by inversion of decidua vera/parietalis - most common typical mechanism; retroplacental clot forms, ovum pushed into uterine cavity
  3. Incomplete expulsion - ovum expelled but placenta and membranes retained (= incomplete abortion)
  4. Missed abortion - ovum detaches sufficiently to kill embryo, but retained in uterus

6. INVESTIGATIONS

  • β-hCG (quantitative serum) - confirm pregnancy, monitor viability; doubling every 48h = normal
  • USG (transvaginal) - gold standard for fetal viability, gestational age, retained POC, rule out ectopic
    • IUP visible on TVS at β-hCG ~1500 mIU/mL (discriminatory zone)
  • CBC - assess blood loss/anemia
  • Blood group + Rh factor - for anti-D immunoglobulin (Rh -ve mothers)
  • Urinalysis - UTI associated with increased fetal wastage

7. MANAGEMENT

TypeManagement
ThreatenedBed rest (not proven), avoid intercourse + tampons; follow-up β-hCG + USG; cannot prevent if inevitable
InevitableUterine evacuation (D&C or medical)
IncompleteUterine evacuation - D&C or misoprostol 600 mcg PO; ergometrine for uterine contraction to expel retained placenta
CompleteConservative; confirm on USG
MissedUterine evacuation; watch for DIC (especially if retained >5 weeks)
SepticIV broad-spectrum antibiotics (ampicillin-sulbactam 3g IV, OR clindamycin 600mg + gentamicin 1-2 mg/kg IV) + uterine evacuation + fluid resuscitation

8. MTP ACT, 1971 (AMENDED 2002 AND 2021)

This is a high-yield topic for NEET PG Forensic Medicine. The MTP (Amendment) Act came into force on 25 March 2021.

Indications (Section 3(2)(b)):

GroundDescriptionGestation Limit
TherapeuticRisk to life or grave injury to physical/mental health of pregnant womanUp to 20 weeks
EugenicSubstantial risk the child would be born with serious physical/mental abnormalityNo upper time limit
SocialFailure of contraceptive device/method (anguish = grave injury to mental health)Up to 20 weeks
HumanitarianPregnancy alleged to result from rape (anguish = grave injury to mental health)Up to 20 weeks
2021 Amendment key change: Upper limit extended from 20 weeks to 24 weeks for certain categories (rape survivors, minors, women with disabilities, etc.) with 2 doctors' opinion. Beyond 24 weeks only with Medical Board approval.

Who Can Perform MTP?

A Registered Medical Practitioner (RMP) who has:
  • PG degree/diploma in Obstetrics & Gynecology, OR
  • Assisted in 25 cases of MTP, OR
  • 6 months experience as house surgeon in OBG in a recognized hospital
For MTP up to 9 weeks using medical methods only (Amendment Rules 2021):
  • 3 months experience in OBG at any hospital, OR
  • Independently performed 10 cases of MTP by medical methods under supervision

Gestational Limits Summary (2021 Amendment):

PeriodRequirements
Up to 20 weeksOpinion of 1 RMP
20-24 weeksOpinion of 2 RMPs (special categories: rape survivors, minors, women with disabilities, fetal anomaly)
>24 weeksState-level Medical Board approval (for substantial fetal anomaly)
EmergencySingle doctor, even without training, even in unrecognized hospital

Consent:

  • Adult (≥18 yrs) woman: her own consent only (husband's consent NOT required)
  • Minor (<18 yrs) or mentally ill: guardian's consent required

Venue:

  • Government hospital, OR
  • Hospital recognized by government for this purpose
  • NGOs need a license from government/district-level committee

Penalty for Illegal Abortion:

  • Rigorous imprisonment not less than 2 years, may extend to 7 years

MTP Act vs IPC/BNS:

  • Doctor acting under MTP Act provisions is protected from criminal liability under BNS sections on abortion, if acted in good faith with proper care and skill

9. MTP ACT vs PCPNDT ACT (High-yield Comparison)

FeatureMTP ActPCPNDT Act
ObjectiveLegal termination of pregnancy up to 20 weeks on therapeutic/eugenic/humanitarian/social groundsCheck female feticide; improve sex ratio
Underlying reasonUnwanted/unintended pregnancySon preference, dowry, low valuation of girls
Expected outcomeReduce unsafe abortionsImprove sex ratio

10. CRIMINAL ABORTION (Forensic)

  • Unlawful termination of pregnancy without proper indication
  • Methods used:
    • General methods - drugs (oxytocics, quinine, castor oil), violence
    • Local methods - insertion of instruments, paste, chemicals into uterus
  • Signs: laceration/perforation of uterus, peritonitis, sepsis, hemorrhage
  • Cause of death in criminal abortion: Hemorrhage, sepsis, air embolism, vagal inhibition (reflex cardiac arrest from instrumentation)

11. SPECIAL TOPICS

Carneous (Blood) Mole

  • Formed in missed abortion when fetus dies and is retained
  • Products of conception converted to an ovoid, fleshy mass due to recurrent or slow hemorrhage into chorionic spaces
  • Associated with >8 weeks gestation

Recurrent (Habitual) Abortion

  • 3 or more consecutive spontaneous abortions
  • Investigations: karyotype (both partners), uterine anatomy (HSG, hysteroscopy), antiphospholipid antibodies, thyroid function, luteal phase assessment
  • Most common identified cause: antiphospholipid syndrome (treat with low-dose aspirin + heparin)

Rh-Negative Mother

  • All Rh-negative women with threatened/inevitable/incomplete/complete/missed abortion should receive Anti-D immunoglobulin (300 mcg within 72 hours)

12. QUICK NEET PG RECALL BOX

PointFact
Most common cause of spontaneous abortionChromosomal abnormality (50%)
Most abortions occur before8 weeks (75%)
Threatened abortion - cervical osClosed
Inevitable abortion - cervical osOpen
Habitual abortion =3 or more consecutive
MTP Act passed1971, amended 2002 & 2021
MTP up to 20 weeks needs1 RMP opinion
MTP 20-24 weeks needs2 RMP opinions
MTP >24 weeks needsMedical Board
Eugenic abortion time limitNo upper limit
Consent for adult womanHer own (husband's NOT required)
Penalty for illegal abortion2-7 years rigorous imprisonment
Missed abortion moleCarneous/blood mole
Septic abortion antibioticsAmpicillin-sulbactam OR Clindamycin + Gentamicin
Anti-D needed inAll Rh-negative women with any type of abortion

Sources: The Essentials of Forensic Medicine and Toxicology (36th ed., 2026) - MTP Act; Tintinalli's Emergency Medicine - clinical types/management; Robbins & Cotran Pathologic Basis of Disease - etiology/pathology; Berek & Novak's Gynecology - epidemiology/management; P.C. Dikshit Textbook of Forensic Medicine - legal aspects/classification.
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