attachment
attachment

Chetan of 42 yrs old man came with complaints of fleshy mass in left eye associated with pain and pricking sensation from 4-5months with vision right eye -6/6 and left eye -6/9 improving to 6/6 .with no co morbidities and no past medical history.other ocular findings are normal . Asoct and fnac showed ossn with no deeper involvement and mod dysplasia leading to provisional diagnosis as right eye gelatinous oculo surface squamous neoplasia .treatment included to left eye interferon alpha 2b, 1 percent 5 flurouracil eyedrops (given on and off)and artificial tear drops and further follow up done and shown good results . Make this in to poster presentation for an ophthalmologist in 100 characters

analyse_media
Generating Image

Professional ophthalmology case report poster for a medical conference. Title: "Gelatinous Ocular Surface Squamous Neoplasia (OSSN): A Case Report". Clean academic layout with white background and teal/navy blue color scheme. Sections clearly divided: PATIENT: 42-year-old male | Chetan | No comorbidities CHIEF COMPLAINT: Fleshy mass in left eye with pain and pricking sensation x 4-5 months VISUAL ACUITY: OD: 6/6 | OS: 6/9 improving to 6/6 CLINICAL FINDINGS: Elevated fleshy gelatinous pinkish-red limbal mass on nasal bulbar conjunctiva with corneal encroachment | Significant conjunctival injection | Periocular skin: erythematous papules and plaques INVESTIGATIONS: AS-OCT: No deeper stromal involvement | FNAC: Moderate dysplasia | Diagnosis: Gelatinous Ocular Surface Squamous Neoplasia (OSSN) - Left Eye TREATMENT: Interferon alpha-2b eye drops (topical) | 1% 5-Fluorouracil eye drops (on-and-off regimen) | Artificial tear drops | Regular follow-up OUTCOME: Good clinical response on follow-up Include a small placeholder box labeled "Clinical Photo" on right side. Footer: Ophthalmology Department | Case Report 2026. Use clear medical typography, numbered sections, minimal icons.

Here is the ophthalmology case report poster for Chetan's OSSN presentation:
Gelatinous OSSN Case Report Poster

Quick Summary of the Case (for your reference):
SectionDetails
Patient42M, no comorbidities, no past medical history
ComplaintFleshy mass, pain & pricking sensation in Left Eye x 4-5 months
VAOD: 6/6 / OS: 6/9 (pinhole 6/6)
ClinicalGelatinous, elevated nasal limbal mass with conjunctival injection; periocular papular skin changes
InvestigationsAS-OCT: no deeper involvement; FNAC: moderate dysplasia
DiagnosisGelatinous Ocular Surface Squamous Neoplasia (OSSN) - Left Eye
TreatmentTopical IFN-alpha-2b + 1% 5-FU (on-off) + artificial tears
OutcomeGood response on follow-up

A note on the case: The image clearly shows a prominent gelatinous fleshy limbal mass on the nasal bulbar conjunctiva with encroachment toward the cornea and dilated feeding vessels - classic for gelatinous-type OSSN. The periocular papular skin lesions are a notable associated finding worth documenting.
You can use this poster as a base for your conference presentation. If you need it modified - such as adding the actual clinical photo, changing layout, or adjusting any text - just let me know!
attachment
attachment

What kind off carcinoma can this be

analyse_media
Reading File
Finding Sources
Finding Sources
Reading File
Reading File
This is a very comprehensive picture. Here is a detailed clinical analysis:

Periocular Malignancy - Differential Diagnosis

The image shows a large, exophytic, fungating, centrally ulcerated periocular mass (~2.5-3.5 cm) involving the left upper eyelid with orbital extension, necrotic slough centrally, raised rolled borders, and feeding vascularity. This is an advanced, neglected periocular malignancy. The differentials in order of likelihood are:

1. Sebaceous Gland Carcinoma (Most Likely)

Why it fits best:
  • Location in the upper eyelid is the hallmark - SGC arises from meibomian glands in the tarsal plate and glands of Zeis
  • The yellow-white areas within the necrotic crater reflect the lipid-rich sebaceous content
  • Advanced SGC in neglected cases presents exactly as this - a large fungating, destructive mass
  • SGC is capable of pagetoid spread through conjunctival and skin epithelium, making it appear deceptively large
  • Regional and systemic metastasis and orbital extension are hallmarks of advanced disease
"Sebaceous carcinoma originates from sebaceous glands either in the tarsal plate (meibomian gland) or associated with eyelashes (glands of Zeis) and is capable of producing widespread metastasis resulting in death." - Goldman-Cecil Medicine
Key association: Muir-Torre syndrome (sebaceous tumors + visceral malignancy) - must be excluded.

2. Squamous Cell Carcinoma (SCC)

Why it fits:
  • The deeply ulcerated, crateriform central necrosis with rolled everted margins is classic SCC morphology
  • Rapidly growing and highly aggressive
  • UV exposure is the major risk factor (common in outdoor workers in India)
  • Can invade the orbit and extend to the cavernous sinus via perineural spread if untreated
  • Regional lymph node metastasis is a real risk
"Squamous cell carcinoma can metastasize, most often to regional lymph nodes. It also can invade the orbit and cavernous sinus via perineural spread from untreated lesions on the eyelids." - Goldman-Cecil Medicine

3. Keratoacanthoma (Low-grade SCC variant)

Why it fits:
  • Classically: elevated lesion with rolled margins and a large central ulcer filled with keratin
  • Now classified as low-grade SCC rather than a benign entity
  • The crateriform appearance closely resembles what is seen here
  • Usually involves lower eyelid but can occur anywhere

4. Basal Cell Carcinoma - Neglected/Advanced

Less likely because:
  • BCC is more common on the lower eyelid (this is upper eyelid)
  • BCC rarely grows this large unless neglected for many years
  • BCC does NOT typically metastasize
  • Fungating, rapidly necrotic appearance is atypical for BCC

Summary Table

Feature in ImageSGCSCCBCC
Upper eyelid location✅ ClassicPossibleUncommon
Fungating, necrotic mass✅ Advanced SGC✅ ClassicOnly if neglected
Yellow-white lipid-rich sloughLess specific
Orbital invasionMedial canthus only
Metastatic potential✅ High✅ Moderate✗ Rare

Urgent Next Steps

  1. Incisional biopsy (not excisional given size) - send for histopathology; oil red-O stain if SGC suspected
  2. CT/MRI orbit - assess depth of orbital involvement and intracranial extension
  3. Regional lymph node palpation - preauricular, submandibular, cervical
  4. Systemic staging if metastasis suspected
  5. Dermatology/oncology referral - if Muir-Torre syndrome suspected (SGC + colonic malignancy)
  6. Treatment likely requires orbital exenteration in this advanced case, followed by adjuvant radiotherapy
Bottom line: This is almost certainly Sebaceous Gland Carcinoma or Squamous Cell Carcinoma of the upper eyelid in an advanced, neglected state with orbital invasion. Histopathology is mandatory before any definitive surgical planning.

Make one fake poster presentation for ophthalmologist

Asking for Preferences

Squamous cell carcinoma

Generating Image

Professional ophthalmology medical conference poster presentation. Title: "Advanced Squamous Cell Carcinoma of the Upper Eyelid with Orbital Extension: A Case Report". Academic layout, navy blue and white color scheme with gold accent headers. Portrait orientation. Clearly divided sections with clean medical typography: TOP HEADER BAND (navy blue): Institution: Department of Ophthalmology, Regional Eye Institute | Conference: AIOC 2026 | Authors: Dr. R. Sharma, Dr. P. Mehta, Dr. S. Nair SECTION 1 - INTRODUCTION (gold header): Squamous Cell Carcinoma (SCC) of the eyelid is a rare but aggressive malignancy arising from surface squamous epithelium. UV radiation is the primary risk factor. Advanced neglected cases may present with orbital invasion, perineural spread, and regional lymph node metastasis. Early recognition and biopsy are essential. SECTION 2 - CASE PRESENTATION (gold header): • 58-year-old male farmer, outdoor worker, no comorbidities • Complaints: Rapidly growing mass left upper eyelid x 8 months • Associated: Pain, watering, restricted eye opening • VA: OD 6/6 | OS: Hand movements only • Clinical: 3 cm fungating ulceroproliferative mass, upper eyelid, rolled everted margins, central necrotic crater, orbital extension, proptosis • Lymph nodes: Left preauricular node palpable, 1.5 cm, firm SECTION 3 - INVESTIGATIONS (gold header): • Incisional Biopsy: Moderately differentiated SCC with keratin pearls, perineural invasion • CT Orbit: Mass involving upper lid, preseptal and post-septal extension, no bony destruction • CT Chest/Abdomen: No distant metastasis • HIV, Immunosuppression workup: Negative SECTION 4 - MANAGEMENT (gold header): • Multidisciplinary team: Ophthalmology + Oncology + Radiation Oncology • Surgical: Left orbital exenteration with safe margins • Adjuvant: External beam radiotherapy 60 Gy / 30 fractions • Sentinel node biopsy: Negative for metastasis • Follow-up: 12 months - No local recurrence SECTION 5 - DISCUSSION (gold header): SCC of the eyelid accounts for 5-10% of eyelid malignancies. Neglected tumors risk orbital invasion and cavernous sinus spread via perineural route. Mohs micrographic surgery preferred for early lesions. Exenteration reserved for advanced orbital involvement. Adjuvant radiotherapy reduces recurrence rates. SECTION 6 - CONCLUSION (gold header): Advanced eyelid SCC requires prompt histopathological diagnosis and aggressive multimodal treatment. Awareness, early detection, and sun protection remain key preventive strategies. Two image placeholder boxes labeled "Clinical Photo" and "Histopathology (H&E)" side by side in center. Bottom footer: "Corresponding Author: dr.rsharma@reih.org | Poster No. OP-47"

Here is your sample ophthalmology conference poster for Squamous Cell Carcinoma:
SCC Eyelid Poster Presentation

The poster covers all standard sections expected at a conference like AIOC:
  • Introduction - background on eyelid SCC
  • Case Presentation - fictitious 58-year-old male farmer with advanced neglected disease
  • Investigations - biopsy, CT orbit, staging workup
  • Management - orbital exenteration + adjuvant radiotherapy
  • Discussion - clinical pearls and surgical considerations
  • Conclusion - key takeaway message
You can replace the placeholder image boxes with your actual clinical photos and histopathology slides. Want me to adjust any section, change the institution name, author names, or make it in PPTX/PDF format instead?

Create a downloadable PowerPoint version of this poster

Reading File
Reading File
Reading File
Running Command

ls -la /home/daytona/workspace/ 2>/dev/null || mkdir -p /home/daytona/workspace/…

Running Command

mkdir -p /home/daytona/workspace/scc-poster && node -e "require('pptxgenjs'); co…

Writing File

~/scc-poster/create_poster.js

const pptxgen = require("pptxgenjs");

const pres = new pptxgen();
// Use LAYOUT_WIDE for poster-style (13.3" x 7.5")
pres.layout = "LAYOUT_WIDE";
pres.title = "SCC Eyelid - Case Report Poster";
pres.author = "Dr. R. Sharma";

// ── COLOR PALETTE ──────────────────────────────────────
const NAVY    = "0D2B55";
const GOLD    = "B8860B";
const GOLD_LT = "F0C040";
const WHITE   = "FFFFFF";
const LIGHT   = "E8EFF8";
const DARK_TXT= "1A1A2E";
const GRAY    = "6B7280";
const RED_ACC = "C0392B";

// ── SLIDE 1: POSTER (single slide, landscape) ──────────
const slide = pres.addSlide();

// ── BACKGROUND ──
slide.addShape(pres.shapes.RECTANGLE, {
  x: 0, y: 0, w: 13.3, h: 7.5,
  fill: { color: "F4F6FB" }, line: { color: "F4F6FB" }
});

// ── TOP HEADER BAND ──
slide.addShape(pres.shapes.RECTANGLE, {
  x: 0, y: 0, w: 13.3, h: 1.1,
  fill: { color: NAVY }, line: { color: NAVY }
});

// Gold accent bar under header
slide.addShape(pres.shapes.RECTANGLE, {
  x: 0, y: 1.1, w: 13.3, h: 0.06,
  fill: { color: GOLD_LT }, line: { color: GOLD_LT }
});

// Header: Main title
slide.addText("Advanced Squamous Cell Carcinoma of the Upper Eyelid with Orbital Extension", {
  x: 0.3, y: 0.05, w: 12.7, h: 0.55,
  fontSize: 22, bold: true, color: WHITE, fontFace: "Calibri",
  align: "center", valign: "middle", margin: 0
});

// Header: subtitle / authors
slide.addText("A Case Report    |    Dr. R. Sharma · Dr. P. Mehta · Dr. S. Nair    |    Department of Ophthalmology, Regional Eye Institute", {
  x: 0.3, y: 0.62, w: 9, h: 0.38,
  fontSize: 9.5, color: GOLD_LT, fontFace: "Calibri",
  align: "left", valign: "middle", margin: 0
});

// Header: conference badge (right)
slide.addShape(pres.shapes.ROUNDED_RECTANGLE, {
  x: 11.0, y: 0.15, w: 2.0, h: 0.75,
  fill: { color: GOLD }, line: { color: GOLD }, rectRadius: 0.08
});
slide.addText([
  { text: "AIOC 2026", options: { bold: true, breakLine: true } },
  { text: "Poster OP-47" }
], {
  x: 11.0, y: 0.15, w: 2.0, h: 0.75,
  fontSize: 9, color: WHITE, fontFace: "Calibri",
  align: "center", valign: "middle"
});

// ── LAYOUT: 3 columns below header ──
// Col 1: x=0.15, w=3.9
// Col 2: x=4.25, w=4.9  (center, wider)
// Col 3: x=9.3,  w=3.85

const colY   = 1.25;
const colH   = 5.85;
const boxR   = 0.1;

// Section helper: draws a card with colored header bar
function addCard(slide, pres, x, y, w, h, titleText, titleColor) {
  // Card background
  slide.addShape(pres.shapes.ROUNDED_RECTANGLE, {
    x, y, w, h,
    fill: { color: WHITE },
    line: { color: "D0D8E8", width: 0.75 },
    rectRadius: boxR,
    shadow: { type: "outer", color: "000000", blur: 6, offset: 2, angle: 135, opacity: 0.1 }
  });
  // Title bar
  slide.addShape(pres.shapes.RECTANGLE, {
    x: x + 0.01, y: y + 0.01, w: w - 0.02, h: 0.32,
    fill: { color: titleColor || NAVY }, line: { color: titleColor || NAVY }
  });
  // Section title text
  slide.addText(titleText, {
    x: x + 0.08, y: y + 0.01, w: w - 0.16, h: 0.32,
    fontSize: 10, bold: true, color: WHITE, fontFace: "Calibri",
    align: "left", valign: "middle", margin: 0
  });
}

// ── COLUMN 1 ──────────────────────────────────────────
const c1x = 0.15;
const c1w = 3.9;

// Card 1: Introduction
addCard(slide, pres, c1x, colY, c1w, 2.05, "INTRODUCTION", NAVY);
slide.addText([
  { text: "Squamous Cell Carcinoma (SCC) of the eyelid is a rare but aggressive malignancy arising from the surface squamous epithelium.\n\n", options: { breakLine: false } },
  { text: "UV radiation", options: { bold: true } },
  { text: " is the primary risk factor. Advanced neglected cases may present with orbital invasion, perineural spread, and regional lymph node metastasis.\n\n", options: { breakLine: false } },
  { text: "Incidence:", options: { bold: true } },
  { text: " SCC accounts for 5–10% of all eyelid malignancies. Prompt histopathological diagnosis and multimodal management are critical for a good outcome." }
], {
  x: c1x + 0.1, y: colY + 0.38, w: c1w - 0.2, h: 1.6,
  fontSize: 8.5, color: DARK_TXT, fontFace: "Calibri",
  align: "left", valign: "top", margin: 0
});

// Card 2: Investigations
addCard(slide, pres, c1x, colY + 2.15, c1w, 2.2, "INVESTIGATIONS", "1A5276");
const invItems = [
  { text: "Incisional Biopsy:", bold: true, val: " Moderately differentiated SCC; keratin pearls, perineural invasion confirmed on H&E." },
  { text: "CT Orbit:", bold: true, val: " 3 cm mass, upper lid, preseptal + postseptal extension. No bony destruction." },
  { text: "CT Chest/Abdomen:", bold: true, val: " No distant metastasis detected." },
  { text: "Lymph Node FNAC:", bold: true, val: " Left preauricular node - reactive changes only." },
  { text: "Immunocompromise workup:", bold: true, val: " HIV negative. No immunosuppression." }
];
const invRich = [];
invItems.forEach((item, i) => {
  invRich.push({ text: item.text, options: { bold: true, color: NAVY } });
  invRich.push({ text: item.val + (i < invItems.length - 1 ? "\n" : ""), options: { color: DARK_TXT } });
});
slide.addText(invRich, {
  x: c1x + 0.1, y: colY + 2.15 + 0.38, w: c1w - 0.2, h: 1.76,
  fontSize: 8.2, fontFace: "Calibri", align: "left", valign: "top", margin: 0
});

// Card 3: Conclusion
addCard(slide, pres, c1x, colY + 4.45, c1w, 1.35, "CONCLUSION", RED_ACC);
slide.addText([
  { text: "Advanced eyelid SCC requires ", options: { color: DARK_TXT } },
  { text: "prompt biopsy", options: { bold: true, color: RED_ACC } },
  { text: " and ", options: { color: DARK_TXT } },
  { text: "aggressive multimodal treatment.\n\n", options: { bold: true, color: RED_ACC } },
  { text: "Awareness, early referral to ophthalmology, and ", options: { color: DARK_TXT } },
  { text: "sun protection", options: { bold: true, color: DARK_TXT } },
  { text: " remain the cornerstones of prevention. Orbital exenteration, though disfiguring, may be life-saving in advanced cases.", options: { color: DARK_TXT } }
], {
  x: c1x + 0.1, y: colY + 4.45 + 0.38, w: c1w - 0.2, h: 0.9,
  fontSize: 8.2, fontFace: "Calibri", align: "left", valign: "top", margin: 0
});


// ── COLUMN 2 (CENTER) ──────────────────────────────────
const c2x = 4.25;
const c2w = 4.9;

// Card: Case Presentation
addCard(slide, pres, c2x, colY, c2w, 2.85, "CASE PRESENTATION", "145A32");

const caseItems = [
  ["Patient:", "58-year-old male, outdoor farmer, no comorbidities"],
  ["Complaint:", "Rapidly growing mass in left upper eyelid × 8 months"],
  ["Symptoms:", "Pain, epiphora, restricted eye opening, discharge"],
  ["Visual Acuity:", "OD: 6/6  |  OS: Hand movements only"],
  ["Clinical:", "3 cm fungating ulceroproliferative mass, upper eyelid with rolled everted margins, central necrotic crater, orbital extension, proptosis"],
  ["Lymph Nodes:", "Left preauricular node - 1.5 cm, firm, non-tender"],
  ["Other Eye:", "Right eye - normal, no lesions"],
];
const caseRich = [];
caseItems.forEach((row, i) => {
  caseRich.push({ text: row[0] + " ", options: { bold: true, color: "145A32" } });
  caseRich.push({ text: row[1] + (i < caseItems.length - 1 ? "\n" : ""), options: { color: DARK_TXT } });
});
slide.addText(caseRich, {
  x: c2x + 0.12, y: colY + 0.38, w: c2w - 0.24, h: 2.4,
  fontSize: 8.4, fontFace: "Calibri", align: "left", valign: "top", margin: 0
});

// Card: Management
addCard(slide, pres, c2x, colY + 2.95, c2w, 2.85, "MANAGEMENT & OUTCOME", "6E2FA1");

const mgmtItems = [
  ["MDT:", "Ophthalmology + Oncology + Radiation Oncology"],
  ["Surgery:", "Left orbital exenteration with 5 mm safe margins"],
  ["Histopath:", "pT3 N0 M0 - Moderately differentiated SCC, clear margins"],
  ["Adjuvant RT:", "External beam radiotherapy - 60 Gy / 30 fractions over 6 weeks"],
  ["Sentinel Node:", "Intraoperative biopsy - Negative for metastatic disease"],
  ["Prosthesis:", "Ocular prosthesis fitted at 3 months post-surgery"],
  ["Follow-up:", "12 months - No local recurrence, no distant metastasis"],
  ["Outcome:", "Patient disease-free, functional, returned to daily activities"],
];
const mgmtRich = [];
mgmtItems.forEach((row, i) => {
  mgmtRich.push({ text: row[0] + " ", options: { bold: true, color: "6E2FA1" } });
  mgmtRich.push({ text: row[1] + (i < mgmtItems.length - 1 ? "\n" : ""), options: { color: DARK_TXT } });
});
slide.addText(mgmtRich, {
  x: c2x + 0.12, y: colY + 2.95 + 0.38, w: c2w - 0.24, h: 2.4,
  fontSize: 8.4, fontFace: "Calibri", align: "left", valign: "top", margin: 0
});


// ── COLUMN 3 ──────────────────────────────────────────
const c3x = 9.3;
const c3w = 3.85;

// Card: Clinical Photo placeholder
addCard(slide, pres, c3x, colY, c3w, 1.9, "CLINICAL PHOTOGRAPH", "7D6608");
slide.addShape(pres.shapes.RECTANGLE, {
  x: c3x + 0.12, y: colY + 0.4, w: c3w - 0.24, h: 1.38,
  fill: { color: "D5D8DC" }, line: { color: "AAB0B8", width: 0.5 }
});
slide.addText("[Insert Clinical Photo Here]", {
  x: c3x + 0.12, y: colY + 0.4, w: c3w - 0.24, h: 1.38,
  fontSize: 9, color: "555555", fontFace: "Calibri",
  align: "center", valign: "middle", italic: true
});

// Card: Histopathology placeholder
addCard(slide, pres, c3x, colY + 2.0, c3w, 1.9, "HISTOPATHOLOGY (H&E)", "7D6608");
slide.addShape(pres.shapes.RECTANGLE, {
  x: c3x + 0.12, y: colY + 2.0 + 0.4, w: c3w - 0.24, h: 1.38,
  fill: { color: "D5D8DC" }, line: { color: "AAB0B8", width: 0.5 }
});
slide.addText("[Insert H&E Slide Here]\nKeratin pearls / Perineural invasion", {
  x: c3x + 0.12, y: colY + 2.0 + 0.4, w: c3w - 0.24, h: 1.38,
  fontSize: 8.5, color: "555555", fontFace: "Calibri",
  align: "center", valign: "middle", italic: true
});

// Card: Discussion
addCard(slide, pres, c3x, colY + 4.0, c3w, 1.8, "DISCUSSION", "1A5276");
slide.addText([
  { text: "• ", options: {} },
  { text: "SCC", options: { bold: true } },
  { text: " = 5–10% of eyelid malignancies\n", options: {} },
  { text: "• Perineural spread", options: { bold: true } },
  { text: " → cavernous sinus risk if untreated\n", options: {} },
  { text: "• Mohs surgery", options: { bold: true } },
  { text: " preferred for early lesions\n", options: {} },
  { text: "• Exenteration", options: { bold: true } },
  { text: " for advanced orbital disease\n", options: {} },
  { text: "• Adjuvant RT", options: { bold: true } },
  { text: " reduces local recurrence\n", options: {} },
  { text: "• UV protection", options: { bold: true } },
  { text: " key in outdoor workers", options: {} }
], {
  x: c3x + 0.1, y: colY + 4.0 + 0.38, w: c3w - 0.2, h: 1.35,
  fontSize: 8.2, color: DARK_TXT, fontFace: "Calibri",
  align: "left", valign: "top", margin: 0
});


// ── FOOTER BAR ──
slide.addShape(pres.shapes.RECTANGLE, {
  x: 0, y: 7.2, w: 13.3, h: 0.3,
  fill: { color: NAVY }, line: { color: NAVY }
});
slide.addText("Corresponding Author: dr.rsharma@reih.org  |  Dept. of Ophthalmology, Regional Eye Institute  |  Poster No. OP-47  |  AIOC Annual Conference 2026", {
  x: 0.2, y: 7.2, w: 12.9, h: 0.3,
  fontSize: 7.5, color: GOLD_LT, fontFace: "Calibri",
  align: "center", valign: "middle", margin: 0
});

// ── WRITE FILE ──
const outPath = "/home/daytona/workspace/scc-poster/SCC_Eyelid_Poster_AIOC2026.pptx";
pres.writeFile({ fileName: outPath }).then(() => {
  console.log("DONE: " + outPath);
}).catch(err => {
  console.error("ERROR:", err.message);
});
Running Command

cd /home/daytona/workspace/scc-poster && node create_poster.js

Your poster PowerPoint is ready for download:

SCC Eyelid Poster AIOC2026

Presentation · PPTX


What's inside the PPTX:
The poster is built as a single wide-format slide (13.3" x 7.5") in a professional 3-column layout:
ColumnContent
LeftIntroduction, Investigations, Conclusion
CentreCase Presentation, Management & Outcome
RightClinical Photo placeholder, H&E placeholder, Discussion
Design highlights:
  • Navy blue header band with gold accents (AIOC 2026 conference badge)
  • Color-coded section cards (green = clinical, purple = management, red = conclusion)
  • Footer with author contact and poster number
  • Two image placeholder boxes - just replace with your actual clinical photo and histopathology slide
To edit: open in PowerPoint, click any text box to update content, and drag your photos into the placeholder boxes.

Give a brief introduction about squamous cell carcinoma for an ophthalmologist

Finding Sources
Finding Sources
Finding Sources
Finding Sources
Reading File
Finding Sources
Reading File
Finding Sources
Finding Sources
Reading File
Here is a concise, ophthalmology-focused introduction to Squamous Cell Carcinoma:

Squamous Cell Carcinoma - Introduction for Ophthalmologists

Definition & Overview

Squamous Cell Carcinoma (SCC) is a malignant neoplasm arising from the surface squamous epithelium of the eyelid skin and/or the conjunctival/corneal epithelium (ocular surface). It is the second most common malignant eyelid tumor after basal cell carcinoma, accounting for roughly 5-10% of all eyelid malignancies. Unlike BCC, SCC carries a real risk of regional and distant metastasis, making early recognition clinically important.

Anatomical Sites in Ophthalmology

SCC can occur at two distinct sites:
SiteNotes
Eyelid skinArises from cutaneous squamous epithelium; more common on the lower eyelid and periocular skin
Ocular surface (conjunctiva/cornea)Known as Ocular Surface Squamous Neoplasia (OSSN); arises at the limbus, typically nasal bulbar conjunctiva

Risk Factors

  • Ultraviolet (UV) radiation - the primary and most important risk factor; explains the high incidence in outdoor workers and equatorial populations
  • Immunosuppression - HIV, organ transplant recipients, chronic steroid use (dramatically increases risk and aggressiveness)
  • Xeroderma pigmentosa - DNA repair defect; SCC can appear in childhood
  • Actinic keratosis - the recognized premalignant precursor lesion; appears as a scaly, erythematous flat plaque or cutaneous horn
  • HPV infection - implicated especially in conjunctival SCC/OSSN
  • Prior radiation exposure to the periocular region
  • Chronic ocular surface inflammation

Clinical Presentation

Eyelid SCC:
  • Variable appearance - often resembles BCC clinically
  • May present as a scaly, indurated plaque, a nodule, an ulcerated lesion with rolled everted borders, or a fungating mass in advanced cases
  • Premalignant stage: actinic keratosis (scaly patch) or cutaneous horn
  • Keratoacanthoma - now classified as a low-grade SCC variant; crateriform lesion with central keratin plug and rolled margins
Conjunctival/Limbal SCC (OSSN):
  • Fleshy, gelatinous or leukoplakic mass at the limbus, especially nasal side
  • Feeding blood vessels, irregular surface
  • May spread superficially across the conjunctiva before invading deeper structures

Pathology

On histopathology (H&E staining), SCC shows:
  • Nests and sheets of atypical squamous cells invading the dermis/stroma
  • Keratin pearls (concentric whorls of keratin) - pathognomonic of well-differentiated SCC
  • Intercellular bridges (desmosomes)
  • Nuclear pleomorphism, mitotic figures
  • Perineural invasion - a high-risk feature associated with recurrence and cavernous sinus spread

Why SCC is Dangerous in the Periocular Region

  1. Orbital invasion - the orbit has no strong anatomical barrier; SCC can extend postseptally from the eyelid
  2. Perineural spread - can track along the supraorbital, supratrochlear or infraorbital nerves toward the cavernous sinus - a potentially fatal complication
  3. Regional metastasis - to preauricular, submandibular and cervical lymph nodes
  4. Conjunctival spread - OSSN can spread across the entire ocular surface (cornea, conjunctiva) via pagetoid-like extension
"Squamous cell carcinoma can metastasize, most often to regional lymph nodes. It also can invade the orbit and cavernous sinus via perineural spread from untreated lesions on the eyelids." - Goldman-Cecil Medicine

Workup

  1. Full history - duration, UV exposure, immunosuppression, prior malignancy
  2. Slit-lamp examination - document lesion morphology, telangiectasias, lash loss, lid margin involvement
  3. Lymph node palpation - preauricular, submandibular, cervical nodes
  4. Incisional biopsy - histopathological confirmation is mandatory before definitive treatment
  5. AS-OCT (for OSSN) - assess depth of stromal involvement
  6. CT/MRI orbit - for advanced lesions or suspected orbital extension
  7. Systemic staging if metastasis is suspected

Treatment

StageTreatment
Early/localized eyelid SCCSurgical excision with Mohs micrographic surgery (preferred - maximizes margin control and tissue preservation)
Conjunctival OSSNTopical interferon alpha-2b or 1% 5-fluorouracil (medical treatment); surgical excision with cryotherapy to margins
Advanced with orbital invasionOrbital exenteration + adjuvant radiotherapy (60 Gy / 30 fractions)
Non-surgical candidatesTopical imiquimod, topical/injectable interferon
Post-treatmentFollow-up every 6-12 months; patients with one skin malignancy are at elevated risk for further lesions

Prognosis

  • Early detection = excellent prognosis
  • High-risk features that worsen outcomes: perineural invasion, orbital extension, immunosuppression, xeroderma pigmentosa, incomplete excision margins
  • Neglected cases as seen in resource-limited settings can present as large fungating tumors requiring exenteration, with significant morbidity

Sources: Goldman-Cecil Medicine; Wills Eye Manual 6th Ed.; Kanski's Clinical Ophthalmology 10th Ed.
attachment
attachment

Generate a image of this person after treatment and surgery for scc

I'm not able to generate a modified or altered image of a real, identifiable person — this applies even for medical/educational purposes, as it involves creating a fabricated likeness of a specific individual without verified consent.
What I can do instead:
  1. Generate a generic illustration - an anonymized depiction of a post-orbital exenteration patient (not this specific person) showing the typical post-surgical appearance with a prosthetic eye, for educational use in your poster.
  2. Create a medical diagram - a labeled before/after schematic showing the surgical changes (exenteration, socket healing, prosthesis fitting) without using a real patient's face.
Would either of these work for your presentation? Just let me know which you'd prefer.

Create a generic illustration

Generating Image

Medical illustration showing a generic middle-aged South Asian male patient after successful orbital exenteration surgery for advanced squamous cell carcinoma of the left upper eyelid. Post-operative appearance: the left orbital socket is well-healed with smooth skin coverage over the socket, sutured closed showing mature surgical scar lines around the left orbital rim. The patient is wearing a realistic ocular prosthesis (artificial eye) fitted in the left socket, matching the right eye in color. The right eye appears normal and healthy. The periocular skin is healed and clear, no tumor or mass visible. The patient has a calm, recovered expression. Clean clinical photograph style, neutral background, soft lighting. Educational medical illustration. No blood, no active wounds, healed post-surgical appearance.

Post-operative orbital exenteration - generic medical illustration
This generic illustration shows a post-surgical appearance following orbital exenteration for advanced periocular SCC, depicting:
  • Well-healed orbital socket on the left side with mature scar lines
  • Ocular prosthesis (artificial eye) fitted in the left socket
  • Normal right eye for comparison
  • Clear, tumor-free periocular skin - no residual mass or inflammation
This can be used in your poster or presentation as a representative "post-treatment" image to illustrate the surgical outcome to your audience. Would you like a side-by-side before/after diagram version instead, or this works?
This is a shared conversation. Sign in to Orris to start your own chat.