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pancreatic neuroendocrine tumors diagnosis treatment
pancreatic neuroendocrine tumors 2024 2025 latest guidelines treatment advances
pancreatic neuroendocrine tumor PRRT sunitinib everolimus surgery
pancreatic neuroendocrine tumor treatment guidelines 2024 2025
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PanNEN Comprehensive 2025
Presentation · PPTX
| # | Section | Slides |
|---|---|---|
| 1 | Introduction & Epidemiology | 1–6 |
| 2 | Pathogenesis & Molecular Genetics (2025 proteogenomic data) | 7–9 |
| 3 | WHO 2022 Grading + G3 NET vs NEC distinction | 10–12 |
| 4 | Insulinoma – Whipple's triad, 72-hr fast, imaging, surgery | 13–16 |
| 5 | Gastrinoma & ZES – secretin test, gastrinoma triangle, management | 17–20 |
| 6 | Glucagonoma – 4 D's, NME rash | 21–22 |
| 7 | VIPoma, Somatostatinoma & rare functional tumours | 23–25 |
| 8 | Non-functional PanNETs – incidentaloma, active surveillance | 26–28 |
| 9 | MEN-1 syndrome, genetics, surveillance | 29–31 |
| 10 | Imaging (CT/MRI/EUS/DOTATATE PET) & biomarkers | 32–35 |
| 11 | Treatment – Surgery, SSAs, Everolimus, Sunitinib, Cabozantinib (FDA approved March 2025), PRRT (NETTER-1/2), chemo, NCCN 2025 algorithm, liver mets | 36–45 |
| 12 | Prognosis tables, key trials, exam pearls | 46–50 |
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PanNEN Comprehensive 2025
Presentation · PPTX