CVS CASE SHEET WITH DETAILED HISTORY TAKING FOR MEDICINE POSTINGS

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I now have comprehensive material from Harrison's and Goldman-Cecil to construct a thorough CVS case sheet. Let me compile this into a complete, detailed document.

CVS CASE SHEET — DETAILED HISTORY TAKING FOR MEDICINE POSTINGS

Based on Harrison's Principles of Internal Medicine 22E & Goldman-Cecil Medicine

PART I: PATIENT IDENTIFICATION

FieldDetails
Name
Age
Sex
Occupation
Address
Date of Admission
IP/OP Number
Informant & Reliability

PART II: CHIEF COMPLAINTS

(List in chronological order with duration)
  1. _____________________________ — since ___
  2. _____________________________ — since ___
  3. _____________________________ — since ___

PART III: HISTORY OF PRESENTING ILLNESS (HOPI)

Note: The four cardinal symptoms of cardiovascular disease are chest pain/discomfort, dyspnea, edema, and syncope. Also elicit palpitations, fatigue, and cough. Symptoms provoked by exertion and relieved by rest are characteristic of heart disease; symptoms at rest that resolve with exertion are rarely cardiac. (Harrison's, p. 1885)

A. CHEST PAIN / DISCOMFORT

  • Onset: Sudden / Gradual
  • Duration: Minutes / Hours / Continuous
  • Character: Pressure / Squeezing / Burning / Tearing / Stabbing / Dull ache / Heaviness
  • Site: Retrosternal / Precordial / Left-sided / Back / Epigastric
  • Radiation: Neck / Left shoulder / Left arm / Both arms / Jaw / Back / Abdomen
  • Severity: (0–10 scale)
  • Precipitating factors: Exertion / Emotion / Cold / Meals / Rest
  • Relieving factors: Rest / Sublingual nitrates (response time) / Antacids / Posture (pericarditis — leaning forward)
  • Aggravating factors: Deep inspiration (pleuritic) / Palpation (musculoskeletal) / Swallowing (esophageal)
  • Associated symptoms: Sweating / Nausea / Vomiting / Dyspnea / Syncope / Palpitations / Fever
Differentiating features:
  • Stable angina: Exertional, relieved within 5 min by rest/nitrates
  • Unstable angina/NSTEMI: Rest pain or crescendo pattern, may not resolve quickly
  • STEMI: Severe, prolonged (>20 min), not relieved by nitrates
  • Aortic dissection: Sudden, severe, tearing, radiates to back; ascending → anterior chest, descending → back radiating to abdomen
  • Pericarditis: Sharp, pleuritic, relieved by leaning forward, associated pericardial rub
  • Pulmonary embolism: Pleuritic, with dyspnea and hemoptysis (Goldman-Cecil, p. 2503–2505)

B. DYSPNEA

  • Onset and duration
  • Grade (NYHA Functional Classification):
NYHA ClassDescription
Class INo symptoms with ordinary activity
Class IISlight limitation — symptoms with ordinary exertion (climbing stairs, walking fast)
Class IIIMarked limitation — symptoms with less than ordinary activity
Class IVSymptoms at rest; unable to carry out any physical activity
(Goldman-Cecil, p. 2638)
  • Type of dyspnea:
    • Exertional dyspnea — quantify exercise tolerance (number of stairs, distance on flat)
    • Orthopnea — dyspnea on lying flat; number of pillows used; onset after lying down
    • Paroxysmal Nocturnal Dyspnea (PND) — wakes from sleep breathless, relieved sitting upright; duration before relief
    • Dyspnea at rest
    • Cardiac asthma — wheeze associated with pulmonary congestion

C. PALPITATIONS

  • Onset: Sudden or gradual
  • Offset: Sudden or gradual
  • Character: Fast / Slow / Regular / Irregular / Missed beats / Forceful beats / Fluttering
  • Duration of each episode
  • Frequency
  • Associated symptoms: Presyncope / Syncope / Chest pain / Dyspnea / Polyuria (after SVT — vagal response)
  • Precipitating factors: Exertion / Coffee / Alcohol / Stress / Medications
  • Termination: Spontaneous / Valsalva / Carotid sinus massage / Hospital visit

D. SYNCOPE / PRESYNCOPE

  • Onset: Sudden (cardiac arrhythmia) vs. Prodromal (vasovagal)
  • Posture at time of event
  • Precipitating factors: Exertion (AS, HOCM, pulmonary hypertension) / Micturition / Cough / Change in posture (orthostatic) / Emotional stress
  • Prodrome: Sweating / Nausea / Tunnel vision / Light-headedness
  • Loss of consciousness: Complete/incomplete; duration
  • Convulsions / Tongue bite / Incontinence (exclude seizure)
  • Recovery: Immediate (cardiac arrhythmia) vs. Gradual (vasovagal — residual fatigue)
  • Frequency of episodes
Sudden cardiac death as first manifestation occurs in conditions like hypertrophic cardiomyopathy, prolonged QT syndrome, and severe CAD — a prior history of syncope on exertion is a red flag. (Harrison's, p. 1885)

E. EDEMA

  • Site: Pedal / Sacral / Ascites / Anasarca
  • Onset and progression: Bilateral dependent edema → central edema (gravity-dependent)
  • Pitting / Non-pitting
  • Diurnal variation: Worse in evening (cardiac) vs. constant (renal)
  • Associated symptoms: Dyspnea / Orthopnea / Abdominal distension / Decreased urine output / Facial puffiness (renal/hepatic)

F. FATIGUE / EXERCISE INTOLERANCE

  • Duration
  • Quantify: Activities now versus previously (stairs, walking distance)
  • Associated with dyspnea or chest pain?

G. COUGH / HEMOPTYSIS

  • Dry / Productive
  • Pink frothy sputum (acute pulmonary edema)
  • Hemoptysis (mitral stenosis, pulmonary hypertension, PE)
  • Nocturnal cough (can be an anginal equivalent or heart failure symptom)

H. OTHER CARDIOVASCULAR SYMPTOMS

  • Hoarseness (Ortner's syndrome — compression of left recurrent laryngeal nerve by large left atrium/pulmonary artery in mitral stenosis)
  • Abdominal distension (ascites, hepatic congestion in right heart failure)
  • Cold / Cyanotic extremities (peripheral arterial disease, low cardiac output)
  • Claudication (intermittent — pain in calves/thighs on walking, relieved by rest; indicative of peripheral arterial disease)
  • Headache, visual changes, epistaxis (hypertension)

PART IV: PAST HISTORY

  • Previous cardiac disease (MI, HF, valvular disease, arrhythmias)
  • Rheumatic fever — sore throat episodes, joint pains (migratory polyarthritis), chorea, skin manifestations in childhood; establishes rheumatic valvular disease
  • Hypertension — duration, treatment, control
  • Diabetes mellitus
  • Dyslipidemia
  • Previous cardiac interventions: CABG / PCI / Valvulotomy / Valve replacement / Pacemaker / ICD
  • Previous hospitalisations for cardiac events
  • Tuberculosis (pericarditis, constrictive pericarditis)
  • Thyroid disease (AF, heart failure)
  • Anemia (high-output cardiac failure)
  • Renal disease (hypertension, CKD-related cardiomyopathy)
  • Surgeries (especially cardiac, vascular)

PART V: DRUG HISTORY

  • Current medications with doses and duration
  • Cardiac medications: Antihypertensives / Antiplatelets (aspirin, clopidogrel) / Anticoagulants (warfarin — INR monitoring) / Statins / Diuretics / Digoxin / Beta-blockers / ACE inhibitors/ARBs / Nitrates / Antiarrhythmics
  • Drug allergies (especially aspirin, antibiotics, contrast dyes)
  • Cardiotoxic drugs: Anthracyclines (doxorubicin) / Trastuzumab / NSAIDs / Cocaine / Amphetamines / Clozapine
  • OTC medications / Herbal preparations

PART VI: PERSONAL HISTORY

ParameterDetails
DietVegetarian / Non-vegetarian; Salt intake; Saturated fats
SmokingPack-years (packs/day × years); current or ex-smoker
AlcoholUnits/week; type; duration; binge patterns
Physical activitySedentary / Active; type and frequency
OccupationSedentary / Physically demanding; occupational exposures
SleepHours; snoring/apnea episodes (obstructive sleep apnea → hypertension, AF)
StressPsychosocial stressors

PART VII: FAMILY HISTORY

  • Premature coronary artery disease (first-degree male relative <55 years, female <65 years)
  • Hypertension
  • Diabetes mellitus
  • Dyslipidemia
  • Sudden cardiac death / Cardiomyopathy (HOCM — autosomal dominant)
  • Marfan syndrome (aortic dissection, aortic root dilation)
  • Congenital heart disease
  • Channelopathies (prolonged QT, Brugada syndrome)

PART VIII: MENSTRUAL & OBSTETRIC HISTORY (females)

  • Menstrual history (perimenopause — cardiovascular risk rises)
  • Obstetric history: Gestational hypertension / Pre-eclampsia / Peripartum cardiomyopathy
  • OCP use (thrombotic risk — PE, stroke)

PART IX: SOCIOECONOMIC HISTORY

  • Socioeconomic status (access to treatment, compliance)
  • Insurance / Financial constraints
  • Living conditions

PART X: REVIEW OF SYSTEMS

(Systematic enquiry for cardiovascular-relevant organ systems)
  • CNS: TIA / Stroke (thromboembolic — AF, valvular disease, carotid disease)
  • Respiratory: Wheeze / PND / Cough
  • GI: Nausea, anorexia (hepatic congestion, digoxin toxicity)
  • Renal: Oliguria (low output cardiac failure), nocturia (early heart failure)
  • Peripheral vascular: Claudication, rest pain, cold extremities, varicose veins, DVT / PE
  • Thyroid: Heat/cold intolerance, weight change, tremor (hyper/hypothyroid → cardiac effects)
  • Hematological: Anemia symptoms (high-output failure), bleeding (anticoagulation)

PART XI: FUNCTIONAL STATUS SUMMARY

At time of presentation, patient is NYHA Class ___ based on:
  • Maximum exertion tolerated: _______________________________
  • Symptoms limiting activity: ________________________________
(NYHA and Canadian Cardiovascular Society (CCS) classification for angina should both be recorded where applicable)
CCS Angina Grading:
CCS ClassDescription
IAngina with strenuous exertion only
IISlight limitation — walking >2 blocks or climbing >1 flight of stairs
IIIMarked limitation — walking 1–2 blocks or 1 flight of stairs
IVAngina at rest or with any activity
(Goldman-Cecil, p. 2638)

PART XII: PROVISIONAL DIAGNOSIS

Based on history:
Clinical diagnosis
AetiologyCongenital / Rheumatic / Ischaemic / Hypertensive / Inflammatory / Degenerative
Anatomic abnormalityWhich chambers? Valves? Pericardium? Myocardium?
Physiological derangementLV dysfunction / RV dysfunction / Volume/pressure overload / Obstructive
Functional (NYHA) ClassI / II / III / IV
"The elements of a complete cardiac diagnosis include systematic consideration of the underlying etiology, anatomic abnormalities, physiological derangement, and functional disability." (Harrison's, p. 1885–1886)

PART XIII: OUTLINE FOR PHYSICAL EXAMINATION (to follow history)

General Examination

  • Build, nutrition, body habitus
  • Pallor, Icterus, Cyanosis (central vs peripheral), Clubbing, Edema, Lymphadenopathy
  • Jugular Venous Pressure & waveform (measured at sternal angle — abnormal if >4.5 cm at 30°); waveform analysis (prominent a wave, cannon a wave, v wave in TR)
  • Pulse: Rate / Rhythm / Volume / Character / Vessel wall / Radio-radial/femoral delay
  • Blood pressure: Both arms; postural drop
  • Temperature, respiratory rate

Cardiovascular Examination

  • Inspection of precordium: deformity, visible apex, pulsations, scars
  • Palpation: Apex beat (character, displacement), thrills, parasternal heave
  • Percussion: Cardiac dullness
  • Auscultation: S1, S2, added sounds (S3, S4, opening snap, ejection click), murmurs (timing, site, character, radiation, grading)

Peripheral Signs of Specific Conditions

  • Mitral stenosis: Malar flush, tapping apex
  • Aortic regurgitation: Corrigan's pulse, de Musset's sign, pistol shot sounds, Traube's sign
  • Right heart failure: Raised JVP, hepatomegaly (pulsatile in TR), ascites, peripheral edema
  • Infective endocarditis: Splinter hemorrhages, Osler's nodes, Janeway lesions, Roth spots, splenomegaly

KEY QUICK-REFERENCE TABLE — CARDIAC SYMPTOMS AND THEIR DIFFERENTIALS

SymptomMost likely cardiac causeMust-not-miss differential
Exertional chest painStable angina (CAD)Aortic stenosis, HOCM
Rest chest painACS (unstable angina, STEMI)Aortic dissection, PE, GERD
Sudden tearing back painAortic dissection
Positional pleuritic chest painPericarditisPE, musculoskeletal
Exertional syncopeAS, HOCM, pulmonary HTNArrhythmia
Bilateral pitting leg edema + PNDLeft/biventricular heart failureNephrotic syndrome, cirrhosis
Sudden palpitations + presyncopeSVT, VT
Pink frothy sputum + acute dyspneaAcute pulmonary edema
Hemoptysis + AFMitral stenosisPE, lung malignancy

Sources: Harrison's Principles of Internal Medicine, 22nd Edition (2025), pp. 1885–1906; Goldman-Cecil Medicine, International Edition, pp. 2488–2660

CVS CASE SHEET WITH DETAILED HISTORY TAKING FOR MEDICINE POSTINGS

I already produced a comprehensive CVS Case Sheet for you in my previous response. Here it is again for your reference — fully formatted and ready to use for medicine postings:

CVS CASE SHEET — DETAILED HISTORY TAKING FOR MEDICINE POSTINGS

Based on Harrison's Principles of Internal Medicine 22E & Goldman-Cecil Medicine

PART I: PATIENT IDENTIFICATION

FieldDetails
Name
Age
Sex
Occupation
Address
Date of Admission
IP/OP Number
Informant & Reliability

PART II: CHIEF COMPLAINTS

(List in chronological order with duration)
  1. _____________________________ — since ___
  2. _____________________________ — since ___
  3. _____________________________ — since ___

PART III: HISTORY OF PRESENTING ILLNESS (HOPI)

The four cardinal symptoms of cardiovascular disease are chest pain/discomfort, dyspnea, edema, and syncope. Also elicit palpitations, fatigue, and cough. Symptoms provoked by exertion and relieved by rest are characteristic of heart disease; symptoms at rest that resolve with exertion are rarely cardiac.

A. CHEST PAIN / DISCOMFORT

  • Onset: Sudden / Gradual
  • Duration: Minutes / Hours / Continuous
  • Character: Pressure / Squeezing / Burning / Tearing / Stabbing / Dull ache / Heaviness
  • Site: Retrosternal / Precordial / Left-sided / Back / Epigastric
  • Radiation: Neck / Left shoulder / Left arm / Both arms / Jaw / Back / Abdomen
  • Severity: 0–10 scale
  • Precipitating factors: Exertion / Emotion / Cold / Meals / Rest
  • Relieving factors: Rest / Sublingual nitrates (response time) / Antacids / Posture
  • Aggravating factors: Deep inspiration (pleuritic) / Palpation (musculoskeletal) / Swallowing (esophageal)
  • Associated symptoms: Sweating / Nausea / Vomiting / Dyspnea / Syncope / Palpitations / Fever
Differentiating features by diagnosis:
DiagnosisKey features
Stable anginaExertional, relieved within 5 min by rest or nitrates
Unstable angina / NSTEMIRest pain or crescendo pattern; may not resolve quickly
STEMISevere, prolonged >20 min, not relieved by nitrates
Aortic dissectionSudden, tearing, radiates to back; ascending → anterior chest; descending → back/abdomen
PericarditisSharp, pleuritic, relieved by leaning forward; pericardial rub on exam
Pulmonary embolismPleuritic, with dyspnea and hemoptysis
GERD / esophagealBurning, postprandial, associated with regurgitation, relieved by antacids
MusculoskeletalReproduced by palpation or specific movement

B. DYSPNEA

  • Onset and duration
  • Quantify exercise tolerance: Stairs / flat distance / ADLs
  • NYHA Functional Classification:
NYHA ClassDescription
INo symptoms with ordinary physical activity
IISlight limitation — ordinary activity (stairs, brisk walking) causes symptoms
IIIMarked limitation — less than ordinary activity causes symptoms; comfortable at rest
IVSymptoms at rest; unable to carry out any physical activity without discomfort
  • Type:
    • Exertional dyspnea — onset with activity, relieved by rest
    • Orthopnea — dyspnea on lying flat; number of pillows; onset after lying down (minutes)
    • Paroxysmal Nocturnal Dyspnea (PND) — wakes from sleep breathless; time to relief after sitting/standing up
    • Cardiac asthma — wheeze due to pulmonary congestion (must distinguish from bronchial asthma)
    • Dyspnea at rest — severe decompensation

C. PALPITATIONS

  • Onset: Sudden / Gradual
  • Offset: Sudden / Gradual
  • Character: Fast / Slow / Regular / Irregular / Missed beats / Forceful / Fluttering / Racing
  • Duration of each episode
  • Frequency and pattern
  • Precipitating factors: Exertion / Caffeine / Alcohol / Stress / Medications / Thyroid symptoms
  • Associated symptoms: Presyncope / Syncope / Chest pain / Dyspnea / Polyuria (post-SVT)
  • Termination: Spontaneous / Valsalva manoeuvre / Carotid sinus massage / Required hospital treatment

D. SYNCOPE / PRESYNCOPE

  • Onset: Sudden (cardiac arrhythmia) vs. with prodrome (vasovagal)
  • Posture at the time
  • Precipitating factors:
    • Exertion → aortic stenosis, HOCM, pulmonary hypertension
    • Postural change → orthostatic hypotension
    • Micturition / Cough / Valsalva → situational syncope
    • Emotional stress → vasovagal
  • Prodrome: Light-headedness / Sweating / Nausea / Tunnel vision / Tinnitus
  • Loss of consciousness: Complete / Incomplete; duration
  • Associated features during episode: Convulsions / Tongue bite / Incontinence / Pallor / Cyanosis
  • Recovery: Immediate (arrhythmic) vs. Gradual with fatigue (vasovagal)
  • Frequency of episodes
  • Injuries sustained
Exertional syncope is a red flag — first presentation of HCM or severe AS can be sudden cardiac death.

E. EDEMA

  • Site: Pedal / Ankle / Pretibial / Sacral / Facial / Ascites / Anasarca
  • Onset and progression: Unilateral or bilateral; ascending pattern
  • Pitting: Yes / No; degree (1+ to 4+)
  • Diurnal variation: Worse in evening, better in morning (cardiac) vs. constant (renal)
  • Associated: Dyspnea / Orthopnea / Abdominal distension / Decreased urine output / Facial puffiness
  • Precipitating / aggravating events: Dietary salt excess / Medication non-compliance / Intercurrent illness

F. FATIGUE / EXERCISE INTOLERANCE

  • Duration and progression
  • Activities now vs. previously (quantify: stairs, walking distance)
  • Associated with dyspnea or chest pain?
  • Morning vs. evening predominance

G. COUGH / HEMOPTYSIS

  • Dry / Productive; if productive — colour, blood-staining
  • Pink frothy sputum → acute pulmonary edema
  • Hemoptysis → mitral stenosis (pulmonary venous hypertension), pulmonary embolism, pulmonary hypertension
  • Nocturnal cough (anginal equivalent / early heart failure)
  • Cough worsened by ACE inhibitors (if on treatment)

H. OTHER CARDIAC SYMPTOMS

  • Hoarseness — Ortner's syndrome (enlarged LA or pulmonary artery compressing left recurrent laryngeal nerve — classic in mitral stenosis)
  • Abdominal distension — ascites, hepatomegaly (right heart failure / constrictive pericarditis)
  • Claudication — pain in calves/thighs on walking, relieved by rest (peripheral arterial disease)
  • Cold / cyanotic extremities — low cardiac output, peripheral arterial disease
  • Headache, visual disturbances, epistaxis — hypertension
  • Fever / chills — infective endocarditis, pericarditis, rheumatic carditis
  • Weight loss — cardiac cachexia (advanced heart failure), infective endocarditis
  • Nocturia — early heart failure (nocturnal redistribution of fluid)

PART IV: PAST HISTORY

  • Previous cardiac disease: MI / Heart failure / Valvular disease / Arrhythmia / Congenital heart disease
  • Rheumatic fever: Episodes of sore throat, migratory polyarthritis, chorea, subcutaneous nodules, erythema marginatum in childhood — establishes rheumatic aetiology of valvular disease
  • Hypertension: Duration, treatment, level of control, complications
  • Diabetes mellitus: Duration, type, treatment — silent ischemia, autonomic neuropathy
  • Dyslipidemia: Known levels, treatment
  • Previous cardiac procedures: CABG / PCI / Valvuloplasty / Valve replacement / Pacemaker / ICD implantation / Ablation
  • Previous hospitalisations for cardiac events
  • Tuberculosis — pericarditis, constrictive pericarditis
  • Thyroid disease — hyperthyroidism (AF, high-output failure); hypothyroidism (pericardial effusion, dyslipidemia)
  • Anemia — high-output cardiac failure
  • Renal disease — hypertension, CKD-related cardiomyopathy, fluid overload
  • Connective tissue disease — SLE (Libman-Sacks endocarditis), scleroderma (pulmonary HTN), rheumatoid arthritis (pericarditis)
  • Radiation therapy to chest — pericarditis, accelerated CAD, valvular disease

PART V: DRUG HISTORY

  • Current medications with doses and duration
  • Cardiac drugs: Beta-blockers / ACE inhibitors / ARBs / Diuretics / Digoxin / Antiarrhythmics / Nitrates / Antiplatelet agents / Anticoagulants (warfarin — INR monitoring) / Statins
  • Drug allergies: Aspirin / Antibiotics / Contrast agents / Iodine
  • Cardiotoxic drugs: Anthracyclines (doxorubicin) / Trastuzumab / NSAIDs (fluid retention, worsens HF) / Cocaine / Amphetamines / Clozapine
  • Drugs causing arrhythmia: QT-prolonging agents (antipsychotics, azithromycin, methadone)
  • OTC medications / Herbal preparations
  • Compliance with current medications

PART VI: PERSONAL HISTORY

ParameterDetails to elicit
DietVegetarian / Non-vegetarian; salt intake; saturated fat and cholesterol; fluid intake
SmokingPack-years = packs/day × years; current / ex-smoker; passive exposure
AlcoholUnits/week; type; duration; binge patterns; liver implications
Physical activitySedentary / Active; type, frequency, and intensity
OccupationSedentary / Physically demanding; shift work; stress levels
SleepHours; snoring / witnessed apnoea (obstructive sleep apnea → hypertension, AF, RV failure)
Psychosocial stressRecent life events, anxiety, depression

PART VII: FAMILY HISTORY

  • Premature CAD: First-degree male relative <55 years, female <65 years
  • Hypertension
  • Diabetes mellitus
  • Dyslipidemia
  • Sudden cardiac death — arrhythmia syndromes (long QT, Brugada, ARVC)
  • Hypertrophic cardiomyopathy — autosomal dominant; family history of unexplained sudden death
  • Marfan syndrome — aortic root dilation, dissection
  • Dilated cardiomyopathy — familial forms
  • Congenital heart disease (Down syndrome, Turner syndrome associations)
  • Channelopathies

PART VIII: MENSTRUAL & OBSTETRIC HISTORY (females)

  • Menstrual history — irregular cycles, current menopausal status (post-menopause → rising cardiovascular risk)
  • Obstetric history:
    • Gestational hypertension / Pre-eclampsia (future HTN and CAD risk)
    • Peripartum cardiomyopathy
    • Number of pregnancies — significant mitral stenosis may first present in pregnancy (increased cardiac output)
  • Oral contraceptive use — thrombotic risk (PE, stroke, MI especially in smokers)

PART IX: SOCIOECONOMIC HISTORY

  • Socioeconomic status
  • Dietary patterns related to income
  • Access to healthcare and medications
  • Drug compliance in context of affordability
  • Occupation and physical demands
  • Living conditions (crowded → rheumatic fever risk)

PART X: REVIEW OF SYSTEMS

(Cardiovascular-relevant systemic enquiry)
SystemKey questions
CNSTIA / Stroke (embolic — AF, valvular disease, infective endocarditis)
RespiratoryWheeze / PND / Haemoptysis / Pleuritic pain
GINausea / Anorexia / RUQ pain (hepatic congestion); digoxin toxicity symptoms
RenalOliguria (low-output failure) / Nocturia (early HF) / Haematuria (endocarditis)
Peripheral vascularClaudication / Rest pain / Cold extremities / DVT / Varicose veins
ThyroidHeat/cold intolerance / Weight change / Tremor / Palpitations
HaematologicalPallor / Bleeding tendency (anticoagulation) / Bruising
MSKJoint pains (rheumatic fever) / Marfanoid habitus
SkinXanthomas / Xanthelasma (dyslipidemia) / Rashes (SLE, endocarditis peripheral signs)

PART XI: FUNCTIONAL STATUS SUMMARY

At time of presentation, patient is NYHA Class ___
  • Maximum exertion tolerated: ___________________________
  • Symptoms limiting activity: ___________________________
  • CCS Angina Class (if chest pain present): ___
CCS Angina Grading:
CCS ClassDescription
IAngina only with strenuous/prolonged exertion
IISlight limitation — angina walking >2 blocks on level or climbing >1 flight of stairs
IIIMarked limitation — angina walking 1–2 blocks or climbing 1 flight of stairs
IVAngina at rest or with any activity

PART XII: PROVISIONAL DIAGNOSIS FRAMEWORK

Following the New York Heart Association diagnostic framework, a complete cardiac diagnosis should systematically address:
ElementTo be filled
1. AetiologyCongenital / Rheumatic / Ischaemic / Hypertensive / Inflammatory / Infiltrative / Degenerative / Idiopathic
2. Anatomic abnormalityChambers involved (hypertrophy/dilatation); valve(s) affected (stenosis/regurgitation); pericardium; prior MI
3. Physiological derangementLV systolic/diastolic dysfunction; RV failure; Volume/pressure overload; Obstructive physiology; Arrhythmia
4. Functional disabilityNYHA Class I / II / III / IV

PART XIII: OUTLINE FOR PHYSICAL EXAMINATION (follows history)

General Examination

  • Built / nutrition / body habitus (cachexia, Marfanoid)
  • Pallor (anemia → high output failure)
  • Icterus (right heart failure → hepatic congestion)
  • Cyanosis: Central (cardiac shunt, pulmonary HTN) vs. Peripheral (low output)
  • Clubbing: Grades I–IV; causes — cyanotic CHD, infective endocarditis
  • Edema: Bilateral pitting pedal — grade and distribution
  • Lymphadenopathy
  • JVP: Measured from sternal angle — abnormal if >4.5 cm at 30°; waveform analysis
    • Prominent a wave → reduced RV compliance (pulmonary HTN, PS)
    • Cannon a wave → AV dissociation (VT, complete heart block)
    • Absent a wave → atrial fibrillation
    • Large v wave → tricuspid regurgitation
  • Pulse: Rate / Rhythm / Volume / Character (collapsing, plateau, bisferiens, alternans) / Vessel wall / Radio-radial and radio-femoral delay
  • Blood pressure: Both arms; postural measurements

Cardiovascular Examination

  • Inspection: Precordial deformity, visible apex, visible pulsations, scars (sternotomy, lateral thoracotomy), pacemaker bulge
  • Palpation: Apex beat (site, character — tapping, heaving, thrusting, dyskinetic); thrills (systolic/diastolic); left / right parasternal heave; palpable P2
  • Percussion: Left and right borders of cardiac dullness
  • Auscultation:
    • Heart sounds: S1 (mitral + tricuspid closure), S2 (A2 + P2 — splitting, intensity); S3 (volume overload / HF); S4 (reduced compliance / hypertrophy)
    • Added sounds: Opening snap (MS), ejection click (AS, PS, bicuspid AV), mid-systolic click (MVP), pericardial rub, pericardial knock
    • Murmurs: Timing / Site of maximum intensity / Character / Radiation / Grading (Levine 1–6) / Effect of respiration (right-sided louder on inspiration — Carvallo's sign)

Peripheral Cardiovascular Signs by Condition

ConditionPeripheral signs to seek
Aortic regurgitationCollapsing (water-hammer) pulse; wide pulse pressure; Corrigan's sign; de Musset's sign; Duroziez's sign; Traube's pistol shots; Quincke's pulsation
Mitral stenosisMalar flush; tapping apex; loud S1; opening snap; mid-diastolic rumble
Right heart failureRaised JVP; hepatomegaly (pulsatile in TR); ascites; bilateral pitting edema
Infective endocarditisSplinter haemorrhages; Osler's nodes (painful, finger pulps); Janeway lesions (painless, palms/soles); Roth spots (fundoscopy); splenomegaly; haematuria
HypertensionLoud A2; S4; arteriovenous nipping on fundoscopy; renal bruit
Coarctation of aortaRadio-femoral delay; hypertension in arms; scapular pulsations; rib notching on CXR

QUICK REFERENCE — SYMPTOM TO DIAGNOSIS SUMMARY

SymptomLikely cardiac diagnosisMust-not-miss differential
Exertional chest painStable angina (CAD)Severe AS, HOCM
Rest chest painACS (UA/NSTEMI/STEMI)Aortic dissection, PE, GERD
Sudden tearing back painAortic dissection
Positional pleuritic chest painPericarditisPE, musculoskeletal
Exertional syncopeSevere AS, HOCM, pulmonary HTNArrhythmia
Bilateral pitting edema + PNDLeft/biventricular heart failureNephrotic syndrome, cirrhosis
Sudden-onset palpitations + presyncopeSVT, VT, AF
Pink frothy sputum + acute dyspneaAcute pulmonary edema
Hemoptysis + AFMitral stenosisPE, lung malignancy
Hoarseness + cardiac signsOrtner's syndrome (MS)
Fever + new murmurInfective endocarditis
Childhood arthritis + current murmurRheumatic valvular disease

Sources: Harrison's Principles of Internal Medicine, 22nd Edition (2025 McGraw-Hill), pp. 1885–1906; Goldman-Cecil Medicine, International Edition, pp. 2488–2660
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