I now have comprehensive material from Harrison's and Goldman-Cecil to construct a thorough CVS case sheet. Let me compile this into a complete, detailed document.
CVS CASE SHEET — DETAILED HISTORY TAKING FOR MEDICINE POSTINGS
Based on Harrison's Principles of Internal Medicine 22E & Goldman-Cecil Medicine
PART I: PATIENT IDENTIFICATION
| Field | Details |
|---|
| Name | |
| Age | |
| Sex | |
| Occupation | |
| Address | |
| Date of Admission | |
| IP/OP Number | |
| Informant & Reliability | |
PART II: CHIEF COMPLAINTS
(List in chronological order with duration)
- _____________________________ — since ___
- _____________________________ — since ___
- _____________________________ — since ___
PART III: HISTORY OF PRESENTING ILLNESS (HOPI)
Note: The four cardinal symptoms of cardiovascular disease are chest pain/discomfort, dyspnea, edema, and syncope. Also elicit palpitations, fatigue, and cough. Symptoms provoked by exertion and relieved by rest are characteristic of heart disease; symptoms at rest that resolve with exertion are rarely cardiac.
(Harrison's, p. 1885)
A. CHEST PAIN / DISCOMFORT
- Onset: Sudden / Gradual
- Duration: Minutes / Hours / Continuous
- Character: Pressure / Squeezing / Burning / Tearing / Stabbing / Dull ache / Heaviness
- Site: Retrosternal / Precordial / Left-sided / Back / Epigastric
- Radiation: Neck / Left shoulder / Left arm / Both arms / Jaw / Back / Abdomen
- Severity: (0–10 scale)
- Precipitating factors: Exertion / Emotion / Cold / Meals / Rest
- Relieving factors: Rest / Sublingual nitrates (response time) / Antacids / Posture (pericarditis — leaning forward)
- Aggravating factors: Deep inspiration (pleuritic) / Palpation (musculoskeletal) / Swallowing (esophageal)
- Associated symptoms: Sweating / Nausea / Vomiting / Dyspnea / Syncope / Palpitations / Fever
Differentiating features:
- Stable angina: Exertional, relieved within 5 min by rest/nitrates
- Unstable angina/NSTEMI: Rest pain or crescendo pattern, may not resolve quickly
- STEMI: Severe, prolonged (>20 min), not relieved by nitrates
- Aortic dissection: Sudden, severe, tearing, radiates to back; ascending → anterior chest, descending → back radiating to abdomen
- Pericarditis: Sharp, pleuritic, relieved by leaning forward, associated pericardial rub
- Pulmonary embolism: Pleuritic, with dyspnea and hemoptysis
(Goldman-Cecil, p. 2503–2505)
B. DYSPNEA
- Onset and duration
- Grade (NYHA Functional Classification):
| NYHA Class | Description |
|---|
| Class I | No symptoms with ordinary activity |
| Class II | Slight limitation — symptoms with ordinary exertion (climbing stairs, walking fast) |
| Class III | Marked limitation — symptoms with less than ordinary activity |
| Class IV | Symptoms at rest; unable to carry out any physical activity |
(Goldman-Cecil, p. 2638)
- Type of dyspnea:
- Exertional dyspnea — quantify exercise tolerance (number of stairs, distance on flat)
- Orthopnea — dyspnea on lying flat; number of pillows used; onset after lying down
- Paroxysmal Nocturnal Dyspnea (PND) — wakes from sleep breathless, relieved sitting upright; duration before relief
- Dyspnea at rest
- Cardiac asthma — wheeze associated with pulmonary congestion
C. PALPITATIONS
- Onset: Sudden or gradual
- Offset: Sudden or gradual
- Character: Fast / Slow / Regular / Irregular / Missed beats / Forceful beats / Fluttering
- Duration of each episode
- Frequency
- Associated symptoms: Presyncope / Syncope / Chest pain / Dyspnea / Polyuria (after SVT — vagal response)
- Precipitating factors: Exertion / Coffee / Alcohol / Stress / Medications
- Termination: Spontaneous / Valsalva / Carotid sinus massage / Hospital visit
D. SYNCOPE / PRESYNCOPE
- Onset: Sudden (cardiac arrhythmia) vs. Prodromal (vasovagal)
- Posture at time of event
- Precipitating factors: Exertion (AS, HOCM, pulmonary hypertension) / Micturition / Cough / Change in posture (orthostatic) / Emotional stress
- Prodrome: Sweating / Nausea / Tunnel vision / Light-headedness
- Loss of consciousness: Complete/incomplete; duration
- Convulsions / Tongue bite / Incontinence (exclude seizure)
- Recovery: Immediate (cardiac arrhythmia) vs. Gradual (vasovagal — residual fatigue)
- Frequency of episodes
Sudden cardiac death as first manifestation occurs in conditions like hypertrophic cardiomyopathy, prolonged QT syndrome, and severe CAD — a prior history of syncope on exertion is a red flag. (Harrison's, p. 1885)
E. EDEMA
- Site: Pedal / Sacral / Ascites / Anasarca
- Onset and progression: Bilateral dependent edema → central edema (gravity-dependent)
- Pitting / Non-pitting
- Diurnal variation: Worse in evening (cardiac) vs. constant (renal)
- Associated symptoms: Dyspnea / Orthopnea / Abdominal distension / Decreased urine output / Facial puffiness (renal/hepatic)
F. FATIGUE / EXERCISE INTOLERANCE
- Duration
- Quantify: Activities now versus previously (stairs, walking distance)
- Associated with dyspnea or chest pain?
G. COUGH / HEMOPTYSIS
- Dry / Productive
- Pink frothy sputum (acute pulmonary edema)
- Hemoptysis (mitral stenosis, pulmonary hypertension, PE)
- Nocturnal cough (can be an anginal equivalent or heart failure symptom)
H. OTHER CARDIOVASCULAR SYMPTOMS
- Hoarseness (Ortner's syndrome — compression of left recurrent laryngeal nerve by large left atrium/pulmonary artery in mitral stenosis)
- Abdominal distension (ascites, hepatic congestion in right heart failure)
- Cold / Cyanotic extremities (peripheral arterial disease, low cardiac output)
- Claudication (intermittent — pain in calves/thighs on walking, relieved by rest; indicative of peripheral arterial disease)
- Headache, visual changes, epistaxis (hypertension)
PART IV: PAST HISTORY
- Previous cardiac disease (MI, HF, valvular disease, arrhythmias)
- Rheumatic fever — sore throat episodes, joint pains (migratory polyarthritis), chorea, skin manifestations in childhood; establishes rheumatic valvular disease
- Hypertension — duration, treatment, control
- Diabetes mellitus
- Dyslipidemia
- Previous cardiac interventions: CABG / PCI / Valvulotomy / Valve replacement / Pacemaker / ICD
- Previous hospitalisations for cardiac events
- Tuberculosis (pericarditis, constrictive pericarditis)
- Thyroid disease (AF, heart failure)
- Anemia (high-output cardiac failure)
- Renal disease (hypertension, CKD-related cardiomyopathy)
- Surgeries (especially cardiac, vascular)
PART V: DRUG HISTORY
- Current medications with doses and duration
- Cardiac medications: Antihypertensives / Antiplatelets (aspirin, clopidogrel) / Anticoagulants (warfarin — INR monitoring) / Statins / Diuretics / Digoxin / Beta-blockers / ACE inhibitors/ARBs / Nitrates / Antiarrhythmics
- Drug allergies (especially aspirin, antibiotics, contrast dyes)
- Cardiotoxic drugs: Anthracyclines (doxorubicin) / Trastuzumab / NSAIDs / Cocaine / Amphetamines / Clozapine
- OTC medications / Herbal preparations
PART VI: PERSONAL HISTORY
| Parameter | Details |
|---|
| Diet | Vegetarian / Non-vegetarian; Salt intake; Saturated fats |
| Smoking | Pack-years (packs/day × years); current or ex-smoker |
| Alcohol | Units/week; type; duration; binge patterns |
| Physical activity | Sedentary / Active; type and frequency |
| Occupation | Sedentary / Physically demanding; occupational exposures |
| Sleep | Hours; snoring/apnea episodes (obstructive sleep apnea → hypertension, AF) |
| Stress | Psychosocial stressors |
PART VII: FAMILY HISTORY
- Premature coronary artery disease (first-degree male relative <55 years, female <65 years)
- Hypertension
- Diabetes mellitus
- Dyslipidemia
- Sudden cardiac death / Cardiomyopathy (HOCM — autosomal dominant)
- Marfan syndrome (aortic dissection, aortic root dilation)
- Congenital heart disease
- Channelopathies (prolonged QT, Brugada syndrome)
PART VIII: MENSTRUAL & OBSTETRIC HISTORY (females)
- Menstrual history (perimenopause — cardiovascular risk rises)
- Obstetric history: Gestational hypertension / Pre-eclampsia / Peripartum cardiomyopathy
- OCP use (thrombotic risk — PE, stroke)
PART IX: SOCIOECONOMIC HISTORY
- Socioeconomic status (access to treatment, compliance)
- Insurance / Financial constraints
- Living conditions
PART X: REVIEW OF SYSTEMS
(Systematic enquiry for cardiovascular-relevant organ systems)
- CNS: TIA / Stroke (thromboembolic — AF, valvular disease, carotid disease)
- Respiratory: Wheeze / PND / Cough
- GI: Nausea, anorexia (hepatic congestion, digoxin toxicity)
- Renal: Oliguria (low output cardiac failure), nocturia (early heart failure)
- Peripheral vascular: Claudication, rest pain, cold extremities, varicose veins, DVT / PE
- Thyroid: Heat/cold intolerance, weight change, tremor (hyper/hypothyroid → cardiac effects)
- Hematological: Anemia symptoms (high-output failure), bleeding (anticoagulation)
PART XI: FUNCTIONAL STATUS SUMMARY
At time of presentation, patient is NYHA Class ___ based on:
- Maximum exertion tolerated: _______________________________
- Symptoms limiting activity: ________________________________
(NYHA and Canadian Cardiovascular Society (CCS) classification for angina should both be recorded where applicable)
CCS Angina Grading:
| CCS Class | Description |
|---|
| I | Angina with strenuous exertion only |
| II | Slight limitation — walking >2 blocks or climbing >1 flight of stairs |
| III | Marked limitation — walking 1–2 blocks or 1 flight of stairs |
| IV | Angina at rest or with any activity |
(Goldman-Cecil, p. 2638)
PART XII: PROVISIONAL DIAGNOSIS
Based on history:
| |
|---|
| Clinical diagnosis | |
| Aetiology | Congenital / Rheumatic / Ischaemic / Hypertensive / Inflammatory / Degenerative |
| Anatomic abnormality | Which chambers? Valves? Pericardium? Myocardium? |
| Physiological derangement | LV dysfunction / RV dysfunction / Volume/pressure overload / Obstructive |
| Functional (NYHA) Class | I / II / III / IV |
"The elements of a complete cardiac diagnosis include systematic consideration of the underlying etiology, anatomic abnormalities, physiological derangement, and functional disability."
(Harrison's, p. 1885–1886)
PART XIII: OUTLINE FOR PHYSICAL EXAMINATION (to follow history)
General Examination
- Build, nutrition, body habitus
- Pallor, Icterus, Cyanosis (central vs peripheral), Clubbing, Edema, Lymphadenopathy
- Jugular Venous Pressure & waveform (measured at sternal angle — abnormal if >4.5 cm at 30°); waveform analysis (prominent a wave, cannon a wave, v wave in TR)
- Pulse: Rate / Rhythm / Volume / Character / Vessel wall / Radio-radial/femoral delay
- Blood pressure: Both arms; postural drop
- Temperature, respiratory rate
Cardiovascular Examination
- Inspection of precordium: deformity, visible apex, pulsations, scars
- Palpation: Apex beat (character, displacement), thrills, parasternal heave
- Percussion: Cardiac dullness
- Auscultation: S1, S2, added sounds (S3, S4, opening snap, ejection click), murmurs (timing, site, character, radiation, grading)
Peripheral Signs of Specific Conditions
- Mitral stenosis: Malar flush, tapping apex
- Aortic regurgitation: Corrigan's pulse, de Musset's sign, pistol shot sounds, Traube's sign
- Right heart failure: Raised JVP, hepatomegaly (pulsatile in TR), ascites, peripheral edema
- Infective endocarditis: Splinter hemorrhages, Osler's nodes, Janeway lesions, Roth spots, splenomegaly
KEY QUICK-REFERENCE TABLE — CARDIAC SYMPTOMS AND THEIR DIFFERENTIALS
| Symptom | Most likely cardiac cause | Must-not-miss differential |
|---|
| Exertional chest pain | Stable angina (CAD) | Aortic stenosis, HOCM |
| Rest chest pain | ACS (unstable angina, STEMI) | Aortic dissection, PE, GERD |
| Sudden tearing back pain | Aortic dissection | |
| Positional pleuritic chest pain | Pericarditis | PE, musculoskeletal |
| Exertional syncope | AS, HOCM, pulmonary HTN | Arrhythmia |
| Bilateral pitting leg edema + PND | Left/biventricular heart failure | Nephrotic syndrome, cirrhosis |
| Sudden palpitations + presyncope | SVT, VT | |
| Pink frothy sputum + acute dyspnea | Acute pulmonary edema | |
| Hemoptysis + AF | Mitral stenosis | PE, lung malignancy |
Sources: Harrison's Principles of Internal Medicine, 22nd Edition (2025), pp. 1885–1906; Goldman-Cecil Medicine, International Edition, pp. 2488–2660