Write it in better words such that outside diagnosis of aosd foes not

Write it in better words such that outside diagnosis of aosd foes not sound wrong

Reading File

Running Command

cd /tmp/workspace/attachments/ad57ebf3-4f0c-459f-8947-a1c1549c06a3/ && python -c " from markitdown import MarkItDown print(MarkItDown().convert('abstract.docx').text_content)"

Running Command

cd /tmp/workspace/attachments/ad57ebf3-4f0c-459f-8947-a1c1549c06a3/ && python -c " import docx d=docx.Document('abstract.docx') for p in d.paragraphs: print(repr(p.style.name), p.text) print(len(d.tables)) for t in d.tables: for r in t.rows: print([c.text for c in r.cells]) "

Finding Sources

Running Command

mkdir -p /tmp/workspace/abstract-edit && cd /tmp/workspace/abstract-edit && cp /tmp/workspace/attachments/ad57ebf3-4f0c-459f-8947-a1c1549c06a3/abstract.docx orig.docx && python - <<'EOF' import docx d=docx.Document('orig.docx') P=d.paragraphs new={ 0:"Anti-Jo-1 and Anti-Ro52 Positive Overlap Myositis With Normal CPK Presenting as an Adult-Onset Still's Disease-Like Illness and Responding to Rituximab", 1:"Case History: A 31-year-old woman presented in December 2025 with 1 to 1.5 years of recurrent high-grade fever, polyarthralgia with 30 minutes of morning stiffness, photosensitive malar rash, and intermittent back pain radiating to the hips and lower limbs. On the basis of this febrile inflammatory presentation, adult-onset Still's disease (AOSD) had been considered as the working diagnosis at another centre, and she had received six doses of cyclophosphamide (last on 18 November 2025) without remission. Rheumatoid factor and ANA by ELISA were negative.", 2:"Diagnosis: Investigations showed neutrophilic leukocytosis (WBC 20.8 x10^3/µL), microcytic anaemia (Hb 9.5 g/dL), ESR 66 mm/h, CRP 178 mg/L, ferritin 202 ng/mL, and CPK 55 U/L. Anti-CCP, ANCA, HIV, hepatitis B and C, malaria, and Widal tests were negative. An extended ANA immunoblot showed anti-Jo-1, anti-Ro52/SSA, and anti-SSB antibodies. MRI of both thighs showed subtle STIR hyperintensity in the quadriceps, adductor, hamstring, sartorius, and gracilis muscles, consistent with myositis. A ferritin level not in the range usually seen in active AOSD, together with this serology and imaging, supported an antisynthetase overlap syndrome as the unifying diagnosis.", 3:"Management: She was treated with methotrexate 20 mg weekly (injectable), hydroxychloroquine 200 mg, prednisolone 15 mg tapering to 10 mg, and short-course NSAIDs. For persistent joint and muscle pain, rituximab 1 g was given on 8 June 2026 and 24 June 2026.", 4:"Discussion: Recurrent fever, arthralgia, rash, and neutrophilic leukocytosis with negative conventional serology closely resemble AOSD, which is a diagnosis of exclusion and a reasonable first working diagnosis in this setting. This case shows that antisynthetase syndrome can present with a similar systemic inflammatory picture. Extended autoantibody testing and imaging helped to refine the diagnosis. A normal CPK does not exclude myositis, and MRI is a useful adjunct. An incomplete response to treatment should prompt diagnostic reassessment, including extended myositis antibody testing. Rituximab is an accepted option in refractory antisynthetase syndrome.", 5:"Outcome: By October 2026, CRP had fallen from 111 to 50 mg/L and ESR from 64 to 19 mm/h. CPK remained 55 U/L, muscle power was 5/5, and no joints were swollen. Residual myalgia, eight tender joints, anaemia, and thrombocytosis persist. She remains under follow-up on maintenance rituximab.", } for i,t in new.items(): p=P[i] for r in p.runs[1:]: r._element.getparent().remove(r._element) if p.runs: p.runs[0].text=t else: p.add_run(t) d.save('abstract_revised.docx') EOF ls -la

I rewrote the abstract so the outside AOSD diagnosis reads as a reasonable working diagnosis, not an error. Your references and structure are unchanged:

abstract revised

Word Document · DOCX

What changed

Title: "AOSD Mimic" is now "Presenting as an Adult-Onset Still's Disease-Like Illness". The case is framed as a similar-looking presentation, and the earlier diagnosis is not called wrong.
Case history: "An outside hospital had diagnosed AOSD" is now "AOSD had been considered as the working diagnosis at another centre, on the basis of this febrile inflammatory presentation".
Diagnosis: "Normal ferritin ... favoured over AOSD" is now "a ferritin level not in the range usually seen in active AOSD, together with this serology and imaging, supported antisynthetase overlap".
Discussion:
- "Can wrongly suggest AOSD" is now "closely resemble AOSD, a diagnosis of exclusion and a reasonable first working diagnosis".
- "Failure of cyclophosphamide should prompt diagnostic review" is now "an incomplete response to treatment should prompt diagnostic reassessment".
- I removed the duplicated "Rituximab is an established option" sentence.
Wording fixes: "anaemia" is spelled the same way throughout, the rituximab dates and doses read more clearly, and the outcome ends with "remains under follow-up on maintenance rituximab".

Points to check in your original

Ferritin of 202 ng/mL: A normal ferritin argues against AOSD but does not exclude it, so I wrote "not in the range usually seen". Please don't strengthen it.
CRP and ESR baselines: The Diagnosis section gives CRP 178 mg/L and ESR 66 mm/h. The Outcome says CRP "fell from 111" and ESR "from 64". If those are the pre-rituximab values from a later date, say so, or readers will see a mismatch.
Cyclophosphamide: It is not a standard AOSD drug. Standard options are steroids, methotrexate, and IL-1 or IL-6 blockade. I left that out of the text because it would sound critical of the outside team. If a reviewer asks, be ready to explain why it was given.
Dates: The follow-up runs to October 2026 and rituximab was given in June 2026, but the patient "presented in December 2025". Confirm the timeline reads correctly.
Rash: A photosensitive malar rash is atypical for AOSD, which usually has an evanescent salmon-coloured rash. You could add this as a point in the discussion.

I did not run a literature search for this rewrite. The edits are to wording, and I did not check your clinical claims against the library or PubMed.

Make the title sound as wonderous and more impressive which may increase the chance of me getting gold medal in poster presentations

Here are title options, from most dramatic to most conservative. Judges respond to a clear hook, but an overclaiming title can hurt you at Q&A, so each one stays accurate.

1. Strongest hook (my pick) The Great Masquerade: Antisynthetase Overlap Myositis With Normal CPK Disguised as Adult-Onset Still's Disease, Unmasked by Extended Antibody Profiling and Tamed With Rituximab

2. Mystery-style Fever Without a Name: When Normal CPK and a "Still's-Like" Illness Concealed Anti-Jo-1 and Anti-Ro52 Antisynthetase Overlap Syndrome

3. Lesson-driven Beyond Still's: Unmasking Anti-Jo-1/Anti-Ro52 Overlap Myositis in a Refractory Febrile Polyarthritis With Normal CPK, and Its Response to Rituximab

4. Short and punchy Not Always Still's: Hidden Antisynthetase Overlap Myositis Behind a Normal CPK, Revealed by Extended Autoantibody Testing

5. Formal, for strict abstract committees Anti-Jo-1 and Anti-Ro52 Positive Overlap Myositis With Normal CPK Presenting as an Adult-Onset Still's Disease-Like Illness: Diagnostic Redirection and Response to Rituximab

Why option 1 works

It gives a story arc (masquerade, unmasking, response to treatment) that judges can follow in seconds.
It names the three things that make the case memorable: normal CPK, the AOSD look-alike, and extended antibody testing as the way out.
"Disguised as" and "masquerade" describe the illness, not the outside team's judgement, so the earlier AOSD diagnosis still reads as reasonable.

Cautions

Don't use words like "cure" or "remission" in the title. Your outcome shows persistent myalgia, eight tender joints, anaemia and thrombocytosis, so "tamed" is the most you can honestly claim. For stricter wording, use "Improving With Rituximab".
Many abstract books limit titles to 15 to 25 words. Option 1 is about 28, so check your limit. Option 4 is the safest on length.
On the poster itself, keep the full descriptive title in the header and add a short tagline beneath it, for example: "Normal CPK does not exclude myositis." That line is the message to leave judges with.

Tell me which option you want and I'll put it into the Word file.

Option 1 but in short

Running Command

cd /tmp/workspace/abstract-edit && python - <<'EOF' import docx d=docx.Document('abstract_revised.docx') p=d.paragraphs[0] p.runs[0].text="The Great Masquerade: Antisynthetase Overlap Myositis With Normal CPK Disguised as Adult-Onset Still's Disease" d.save('abstract_revised_v2.docx') EOF ls /tmp/workspace/abstract-edit

The Great Masquerade: Antisynthetase Overlap Myositis With Normal CPK Disguised as Adult-Onset Still's Disease

This is 15 words. The title in the file is now this version:

abstract revised v2

Word Document · DOCX

If you want it shorter, here are two alternatives:

The Great Masquerade: Hidden Antisynthetase Myositis Behind a Still's-Like Illness (11 words)
The Great Masquerade: Normal CPK, Hidden Antisynthetase Myositis (8 words)

Poster tip: Put the title in the header and add a tagline underneath, for example: "Anti-Jo-1/Anti-Ro52 overlap, unmasked by extended antibody profiling and responsive to rituximab." The tagline carries the details I cut from the title.

Keep the main body except title and references under 280 words

Running Command

cd /tmp/workspace/abstract-edit && python - <<'EOF' import docx d=docx.Document('abstract_revised_v2.docx') P=d.paragraphs new={ 1:"Case History: A 31-year-old woman presented in December 2025 with 1 to 1.5 years of recurrent high-grade fever, polyarthralgia with 30 minutes of morning stiffness, photosensitive malar rash, and back pain radiating to the hips and lower limbs. Adult-onset Still's disease (AOSD) had been considered at another centre, and six doses of cyclophosphamide (last on 18 November 2025) produced no remission. Rheumatoid factor and ANA-ELISA were negative.", 2:"Diagnosis: Investigations showed neutrophilic leukocytosis (WBC 20.8 x10^3/µL), microcytic anaemia (Hb 9.5 g/dL), ESR 66 mm/h, CRP 178 mg/L, ferritin 202 ng/mL, and CPK 55 U/L. Anti-CCP, ANCA, HIV, hepatitis B and C, malaria, and Widal tests were negative. ANA immunoblot showed anti-Jo-1, anti-Ro52/SSA, and anti-SSB antibodies. Thigh MRI showed subtle STIR hyperintensity across multiple muscle groups, consistent with myositis. A ferritin level below that usually seen in active AOSD, with this serology and imaging, supported antisynthetase overlap.", 3:"Management: She received methotrexate 20 mg weekly, hydroxychloroquine 200 mg, prednisolone 15 mg tapering to 10 mg, and short-course NSAIDs. For persistent joint and muscle pain, rituximab 1 g was given on 8 and 24 June 2026.", 4:"Discussion: Fever, arthralgia, rash, and leukocytosis with negative conventional serology closely resemble AOSD, a diagnosis of exclusion and a reasonable first working diagnosis. Extended autoantibody testing and imaging refined the diagnosis. Normal CPK does not exclude myositis, and MRI is a useful adjunct. Incomplete treatment response should prompt diagnostic reassessment. Rituximab is an accepted option in refractory antisynthetase syndrome.", 5:"Outcome: By October 2026, CRP fell from 111 to 50 mg/L and ESR from 64 to 19 mm/h. CPK was 55 U/L, muscle power 5/5, and no joints were swollen. Myalgia, eight tender joints, anaemia, and thrombocytosis persist. She remains on maintenance rituximab.", } for i,t in new.items(): p=P[i] for r in p.runs[1:]: r._element.getparent().remove(r._element) p.runs[0].text=t d.save('abstract_final.docx') print(sum(len(new[i].split()) for i in new)) EOF

Running Command

ls -la /tmp/workspace/abstract-edit/ /tmp/workspace/ 2>&1

Running Command

cd /tmp/workspace/abstract-edit && python - <<'EOF' import docx d=docx.Document('abstract_revised.docx') P=d.paragraphs new={ 0:"The Great Masquerade: Antisynthetase Overlap Myositis With Normal CPK Disguised as Adult-Onset Still's Disease", 1:"Case History: A 31-year-old woman presented in December 2025 with 1 to 1.5 years of recurrent high-grade fever, polyarthralgia with 30 minutes of morning stiffness, photosensitive malar rash, and back pain radiating to the hips and lower limbs. Adult-onset Still's disease (AOSD) had been considered at another centre, and six doses of cyclophosphamide (last on 18 November 2025) produced no remission. Rheumatoid factor and ANA-ELISA were negative.", 2:"Diagnosis: Investigations showed neutrophilic leukocytosis (WBC 20.8 x10^3/µL), microcytic anaemia (Hb 9.5 g/dL), ESR 66 mm/h, CRP 178 mg/L, ferritin 202 ng/mL, and CPK 55 U/L. Anti-CCP, ANCA, HIV, hepatitis B and C, malaria, and Widal tests were negative. ANA immunoblot showed anti-Jo-1, anti-Ro52/SSA, and anti-SSB antibodies. Thigh MRI showed subtle STIR hyperintensity across multiple muscle groups, consistent with myositis. A ferritin level below that usually seen in active AOSD, with this serology and imaging, supported antisynthetase overlap.", 3:"Management: She received methotrexate 20 mg weekly, hydroxychloroquine 200 mg, prednisolone 15 mg tapering to 10 mg, and short-course NSAIDs. For persistent joint and muscle pain, rituximab 1 g was given on 8 and 24 June 2026.", 4:"Discussion: Fever, arthralgia, rash, and leukocytosis with negative conventional serology closely resemble AOSD, a diagnosis of exclusion and a reasonable first working diagnosis. Extended autoantibody testing and imaging refined the diagnosis. Normal CPK does not exclude myositis, and MRI is a useful adjunct. Incomplete treatment response should prompt diagnostic reassessment. Rituximab is an accepted option in refractory antisynthetase syndrome.", 5:"Outcome: By October 2026, CRP fell from 111 to 50 mg/L and ESR from 64 to 19 mm/h. CPK was 55 U/L, muscle power 5/5, and no joints were swollen. Myalgia, eight tender joints, anaemia, and thrombocytosis persist. She remains on maintenance rituximab.", } for i,t in new.items(): p=P[i] for r in p.runs[1:]: r._element.getparent().remove(r._element) p.runs[0].text=t d.save('abstract_final.docx') print(sum(len(new[i].split()) for i in range(1,6))) EOF ls -la

Running Command

cd /tmp/workspace/abstract-edit && python - <<'EOF' import docx d=docx.Document('abstract_revised.docx') P=d.paragraphs new={ 0:"The Great Masquerade: Antisynthetase Overlap Myositis With Normal CPK Disguised as Adult-Onset Still's Disease", 1:"Case History: A 31-year-old woman presented in December 2025 with 1 to 1.5 years of recurrent high-grade fever, polyarthralgia with 30 minutes of morning stiffness, photosensitive malar rash, and back pain radiating to the hips and lower limbs. Adult-onset Still's disease (AOSD) had been considered elsewhere, and six doses of cyclophosphamide (last on 18 November 2025) produced no remission. Rheumatoid factor and ANA-ELISA were negative.", 2:"Diagnosis: Investigations showed neutrophilic leukocytosis (WBC 20.8 x10^3/µL), microcytic anaemia (Hb 9.5 g/dL), ESR 66 mm/h, CRP 178 mg/L, ferritin 202 ng/mL, and CPK 55 U/L. Anti-CCP, ANCA, HIV, hepatitis B and C, malaria, and Widal tests were negative. ANA immunoblot showed anti-Jo-1, anti-Ro52/SSA, and anti-SSB antibodies. Thigh MRI showed subtle STIR hyperintensity in multiple muscle groups, consistent with myositis. Ferritin below that usually seen in active AOSD, with this serology and imaging, supported antisynthetase overlap.", 3:"Management: She received methotrexate 20 mg weekly, hydroxychloroquine 200 mg, prednisolone 15 mg tapering to 10 mg, and short-course NSAIDs. For persistent joint and muscle pain, rituximab 1 g was given on 8 and 24 June 2026.", 4:"Discussion: Fever, arthralgia, rash, and leukocytosis with negative conventional serology closely resemble AOSD, a diagnosis of exclusion and a reasonable first working diagnosis. Extended autoantibody testing and imaging refined the diagnosis. Normal CPK does not exclude myositis, and MRI is a useful adjunct. Incomplete treatment response should prompt diagnostic reassessment. Rituximab is accepted in refractory antisynthetase syndrome.", 5:"Outcome: By October 2026, CRP fell from 111 to 50 mg/L and ESR from 64 to 19 mm/h. CPK was 55 U/L, muscle power 5/5, and no joints were swollen. Myalgia, eight tender joints, anaemia, and thrombocytosis persist. She remains on maintenance rituximab.", } for i,t in new.items(): p=P[i] for r in p.runs[1:]: r._element.getparent().remove(r._element) p.runs[0].text=t d.save('abstract_final.docx') print(sum(len(new[i].split()) for i in range(1,6))) EOF

Running Command

cd /tmp/workspace/abstract-edit && python - <<'EOF' import docx d=docx.Document('abstract_final.docx') P=d.paragraphs rep={ 1:[("Adult-onset Still's disease (AOSD) had been considered elsewhere, and six doses","Adult-onset Still's disease (AOSD) had been considered elsewhere; six doses")], 2:[("Anti-CCP, ANCA, HIV, hepatitis B and C, malaria, and Widal tests were negative.","Anti-CCP, ANCA, HIV, hepatitis B and C, malaria, and Widal tests were negative."), ("Thigh MRI showed subtle STIR hyperintensity in multiple muscle groups, consistent with myositis.","Thigh MRI showed subtle STIR hyperintensity, consistent with myositis.")], 4:[("Extended autoantibody testing and imaging refined the diagnosis. ","Extended autoantibody testing and imaging refined the diagnosis. "), ("Incomplete treatment response should prompt diagnostic reassessment.","Incomplete response should prompt diagnostic reassessment.")], 5:[("She remains on maintenance rituximab.","She continues maintenance rituximab.")], } for i,l in rep.items(): for a,b in l: assert a in P[i].runs[0].text P[i].runs[0].text=P[i].runs[0].text.replace(a,b) d.save('abstract_final.docx') body=[P[i].text for i in range(1,6)] print(sum(len(t.split()) for t in body)) print("\n\n".join(P[i].text for i in range(0,6))) EOF

The body is now 271 words, counting the section labels and excluding the title and references. The file is here:

abstract final

Word Document · DOCX

The Great Masquerade: Antisynthetase Overlap Myositis With Normal CPK Disguised as Adult-Onset Still's Disease

Case History: A 31-year-old woman presented in December 2025 with 1 to 1.5 years of recurrent high-grade fever, polyarthralgia with 30 minutes of morning stiffness, photosensitive malar rash, and back pain radiating to the hips and lower limbs. Adult-onset Still's disease (AOSD) had been considered elsewhere; six doses of cyclophosphamide (last on 18 November 2025) produced no remission. Rheumatoid factor and ANA-ELISA were negative.

Diagnosis: Investigations showed neutrophilic leukocytosis (WBC 20.8 x10^3/µL), microcytic anaemia (Hb 9.5 g/dL), ESR 66 mm/h, CRP 178 mg/L, ferritin 202 ng/mL, and CPK 55 U/L. Anti-CCP, ANCA, HIV, hepatitis B and C, malaria, and Widal tests were negative. ANA immunoblot showed anti-Jo-1, anti-Ro52/SSA, and anti-SSB antibodies. Thigh MRI showed subtle STIR hyperintensity, consistent with myositis. Ferritin below that usually seen in active AOSD, with this serology and imaging, supported antisynthetase overlap.

Management: She received methotrexate 20 mg weekly, hydroxychloroquine 200 mg, prednisolone 15 mg tapering to 10 mg, and short-course NSAIDs. For persistent joint and muscle pain, rituximab 1 g was given on 8 and 24 June 2026.

Discussion: Fever, arthralgia, rash, and leukocytosis with negative conventional serology closely resemble AOSD, a diagnosis of exclusion and a reasonable first working diagnosis. Extended autoantibody testing and imaging refined the diagnosis. Normal CPK does not exclude myositis, and MRI is a useful adjunct. Incomplete response should prompt diagnostic reassessment. Rituximab is accepted in refractory antisynthetase syndrome.

Outcome: By October 2026, CRP fell from 111 to 50 mg/L and ESR from 64 to 19 mm/h. CPK was 55 U/L, muscle power 5/5, and no joints were swollen. Myalgia, eight tender joints, anaemia, and thrombocytosis persist. She continues maintenance rituximab.

What I cut to reach the limit

The list of individual thigh muscle groups. The MRI line now says only "subtle STIR hyperintensity, consistent with myositis".
Repeated phrases in the Discussion, including the duplicate rituximab sentence.
Small wording trims, such as "elsewhere" in place of "at another centre".

Check before submitting

The CRP "111" and ESR "64" in the Outcome differ from the baseline values (178 mg/L and 66 mm/h) in the Diagnosis. If they are pre-rituximab values from a later date, add "pre-rituximab" in front of them. I have 9 words of room.
Some submission portals count "x10^3/µL" or "anti-Ro52/SSA" as more than one word. At 271 words you still have a margin of about 9.
I did not run a literature search for these edits.

Remove the great masquerade

Running Command

cd /tmp/workspace/abstract-edit && ls && python - <<'EOF' import docx d=docx.Document('abstract_final.docx') p=d.paragraphs[0] p.runs[0].text="Antisynthetase Overlap Myositis With Normal CPK Disguised as Adult-Onset Still's Disease" d.save('abstract_final_v2.docx') print(d.paragraphs[0].text) EOF ls

The title now reads:

Antisynthetase Overlap Myositis With Normal CPK Disguised as Adult-Onset Still's Disease

The body is unchanged at 271 words. The updated file is here:

abstract final v2

Word Document · DOCX

"Disguised as" keeps some of the hook without the dramatic phrase. If you want a gentler word, I can use "Mimicking" or "Presenting as" instead. "Mimicking" is the most conventional choice for abstract committees.

This is a shared conversation. Sign in to Orris to start your own chat.