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Cath Lab Duty Doctor - Practical Guide
Welcome to the cath lab! Here is a structured, practical breakdown of your role and what you need to know.
1. Your Core Role as Duty Doctor
As duty doctor in the cath lab, your responsibilities span three phases:
Pre-procedure
- Review the patient's history, ECG, recent labs (CBC, renal function, coagulation, HbA1c for diabetics), and old angiography reports
- Confirm informed consent is obtained
- Check allergies - especially to contrast dye and iodine
- Confirm pre-procedure medications are given
- Ensure IV access, pre-hydration if needed (especially for renal impairment patients)
- Hold metformin 24-48 hours before contrast procedures (risk of lactic acidosis)
- Check if the patient is on anticoagulants (warfarin, NOACs) - may need to be bridged or held
Peri-procedure
- Monitor vitals, ECG, SpO2 continuously
- Anticipate and manage acute complications (see below)
- Assist with medications during the procedure
Post-procedure
- Ensure access site hemostasis (radial or femoral)
- Write post-procedure orders
- Monitor for complications
2. Common Cases You Will Handle
A. Elective Coronary Angiography (Diagnostic)
Patient comes for evaluation of suspected CAD.
Pre-procedure orders:
- NPO 4-6 hours (solids), allow small sips of water up to 2 hours
- Tab. Aspirin 300 mg loading (if not on it already)
- Tab. Clopidogrel 300 mg loading (if PCI anticipated)
- Inj. Heparin will be given in the lab (typically 70-100 units/kg IV)
- Inj. Ondansetron 4 mg IV PRN nausea
- IV fluids: NS 100 ml/hr for renal protection pre-contrast
Post-procedure orders (radial access):
- TR Band / radial compression device for 2 hours, gradually deflate
- Tab. Aspirin 75-150 mg OD (continue)
- Tab. Clopidogrel 75 mg OD (if stent placed - dual antiplatelet for 12 months for ACS, 1-6 months for stable angina)
- Tab. Pantoprazole 40 mg BD (gastroprotection with dual antiplatelet)
- IV fluids NS 500-1000 ml post-procedure for contrast nephropathy prevention
- Check urine output, monitor renal function at 24-48 hours
- Restart metformin after 48 hours only if creatinine is normal
B. STEMI (Primary PCI - Most Urgent Case)
Target: Door-to-balloon time < 90 minutes
The Washington Manual is clear: "Primary PCI is the preferred reperfusion strategy when available within 90 minutes of first medical contact."
Immediate medications (give ASAP before cath lab):
- Tab. Aspirin 300 mg loading (chewable/crushed) - STAT
- Tab. Ticagrelor 180 mg loading (preferred) OR Tab. Prasugrel 60 mg OR Tab. Clopidogrel 300-600 mg
- Inj. Heparin 70-100 units/kg IV bolus (or Bivalirudin as alternative)
- Tab. Atorvastatin 80 mg (high-intensity statin)
- Inj. Nitroglycerin IV 5-10 mcg/min (avoid if SBP <90 mmHg, RV infarct, HR >100 or <50, or recent sildenafil use)
- Inj. Morphine 2-4 mg IV for refractory chest pain
- Oral Beta-blocker (Metoprolol 25-50 mg) - start within 24 hours IF no heart failure, no cardiogenic shock, no advanced heart block, SBP >120, HR 60-110
In the lab: Primary PCI + stenting of culprit vessel. If patient is in cardiogenic shock - culprit-only PCI (not multi-vessel, per CULPRIT-SHOCK trial).
Contraindications to fibrinolytics (if PCI unavailable): Prior intracranial hemorrhage, recent stroke <3 months, active bleeding, aortic dissection, severe hypertension >180/110 uncontrolled.
C. NSTEMI / Unstable Angina
Risk stratify with TIMI score (1 point each):
- Age >65
- Known CAD (stenosis >50%)
- 2+ episodes of chest pain in 24 hours
- ST/T wave changes on ECG
- Elevated cardiac biomarkers (troponin/CK-MB)
- Aspirin use in the last 7 days
- 3+ CAD risk factors (family history, DM, HTN, hyperlipidemia, smoking)
TIMI ≥3 = high risk - urgent angiography within 24 hours
High-risk features requiring urgent angiography <2 hours:
- Recurrent angina despite therapy
- Signs of heart failure / pulmonary edema / shock
- New or worsening MR
- New LBBB
- Sustained VT
Medications:
- Tab. Aspirin 300 mg loading, then 75 mg OD
- Tab. Ticagrelor 180 mg loading, then 90 mg BD OR Clopidogrel 300 mg then 75 mg OD
- Inj. Low-molecular-weight heparin (Enoxaparin) 1 mg/kg SC BD OR Inj. Unfractionated heparin infusion
- Tab. Beta-blocker (Metoprolol 25-50 mg BD - if no contraindications)
- Tab. Isosorbide mononitrate 10 mg TDS or nitrate patch for ongoing angina
- Tab. Atorvastatin 80 mg nocte
- Tab. Pantoprazole 40 mg BD
3. Key Medications & Their Role in Cath Lab
| Drug | Class | Dose | Use |
|---|
| Aspirin | Antiplatelet | 300 mg load, 75 mg OD | All ACS |
| Ticagrelor | Antiplatelet (P2Y12) | 180 mg load, 90 mg BD | ACS (preferred) |
| Clopidogrel | Antiplatelet (P2Y12) | 300-600 mg load, 75 mg OD | ACS / fibrinolysis |
| UFH (Heparin) | Anticoagulant | 70-100 U/kg IV bolus | PCI during procedure |
| Enoxaparin | LMWH | 1 mg/kg SC BD | NSTEMI/AUA medical management |
| Bivalirudin | DTI | 0.75 mg/kg bolus + 1.75 mg/kg/hr | Alternative to heparin in PCI |
| Atorvastatin | Statin | 80 mg nocte | All ACS - start immediately |
| Metoprolol | Beta-blocker | 25-50 mg BD oral | STEMI, tachyarrhythmias (if no contraindications) |
| Nitroglycerin | Nitrate | IV drip or sublingual | Chest pain, HTN control |
| Morphine | Opioid | 2-4 mg IV | Refractory chest pain |
4. Complications to Watch For
| Complication | Signs | Action |
|---|
| Contrast allergy / anaphylaxis | Urticaria, bronchospasm, hypotension | Inj. Adrenaline 0.5 mg IM, IV antihistamine, steroids, fluids |
| Contrast-induced nephropathy | Rise in creatinine 24-48 hrs post | Pre-hydrate, N-acetylcysteine, avoid nephrotoxins, hold metformin |
| Access site hematoma (femoral) | Expanding groin swelling | Manual pressure, reverse heparin with protamine if needed |
| Radial artery spasm | Pain, resistance during procedure | Intracoronary / intra-arterial cocktail (verapamil + nitroglycerin + lidocaine) |
| No-reflow / slow flow | Persistent ST elevation after PCI | Intracoronary adenosine, verapamil, or nitroprusside |
| Tamponade | Hypotension, JVD, muffled sounds, equalization of pressures | Emergency pericardiocentesis |
| Arrhythmia (VF/VT) | Sudden hemodynamic collapse | Defibrillation (200J biphasic), CPR protocol |
| Vasovagal reaction | Bradycardia + hypotension | Atropine 0.6-1 mg IV, IV fluids, Trendelenburg position |
5. Emergency Drugs to Know (Keep at Bedside in Cath Lab)
- Inj. Atropine 0.6 mg IV (bradycardia, vasovagal)
- Inj. Adrenaline/Epinephrine 1 mg IV (cardiac arrest, anaphylaxis)
- Inj. Amiodarone 150-300 mg IV slow (VT/VF resistant to shock)
- Inj. Dopamine/Noradrenaline infusion (cardiogenic shock)
- Inj. Protamine sulfate (reverses UFH if excess bleeding)
- Inj. Adenosine (SVT, no-reflow)
- Inj. Furosemide 40 mg IV (acute pulmonary edema, fluid overload)
6. Practical Tips for New Cath Lab Doctors
- Always check renal function before contrast - if eGFR <30, alert senior, consider pre-hydration or iso-osmolar contrast
- Know the TR band protocol - radial access hemostasis takes 2-4 hours; deflate slowly to prevent re-bleeding
- ECG interpretation is key - You must recognize STEMI, posterior MI (ST depression V1-V3 = posterior STEMI), RV infarct (ST elevation in V4R)
- RV infarct rules: Give IV fluids (RV is preload-dependent), avoid nitrates, diuretics
- Keep a short handover note for each patient - time of arrival, procedure done, sheath removed, current status, any issues
- Don't hesitate to call your senior/interventional cardiologist - cath lab complications can escalate fast
- Contrast pre-medication for allergy history: Methylprednisolone 32 mg oral 12 and 2 hours before + Diphenhydramine 50 mg 1 hour before
This guide covers the vast majority of day-to-day cath lab duty scenarios. As you get more exposure, the rhythm of managing pre-cath workups, monitoring during cases, and handling post-procedure care will become second nature. When in doubt, always escalate early - no senior cardiologist minds being called. - The Washington Manual of Medical Therapeutics