Here is your full case presentation on schizophrenia, written as if you are presenting it live right now. Follow each section in order.
CASE STUDY PRESENTATION: SCHIZOPHRENIA
1. SOCIO-DEMOGRAPHIC DATA
Patient: Mr. R.C.
Age: 24 years old
Sex: Male
Civil Status: Single
Religion: Roman Catholic
Nationality: Filipino
Highest Educational Attainment: College level (2nd year, discontinued)
Occupation: Currently unemployed; previously a fast-food service crew
Address: Brgy. San Roque, Quezon City
Date of Admission: May 5, 2026
Ward: Male Psychiatric Ward, Room 3
Admitting Diagnosis: Schizophrenia, Paranoid Type (DSM-5: Schizophrenia Spectrum and Other Psychotic Disorders)
Admitting Physician: Dr. M. Santos, Psychiatry
Chief Complaint: Hearing voices, suspiciousness, and refusal to eat for 3 days
Source of Information: Patient (poor historian), mother (primary informant), medical chart
2. HISTORY AND MSE FINDINGS
History of Present Illness
Mr. R.C. is a 24-year-old male with a known 3-year history of schizophrenia, admitted for the third time due to relapse. His mother reports that approximately 2 weeks prior to admission, he stopped taking his medications (Risperidone 2mg BID) without the doctor's advice. He became increasingly withdrawn, stayed in his room for days, refused to eat because he believed his food was "poisoned by neighbors," and began shouting at unseen people at night. On the day of admission, he attempted to leave the house with a kitchen knife, believing people were "coming to kill him."
Past Psychiatric History: Two previous admissions (2023, 2025) for acute psychotic episodes; started on Risperidone; non-compliant between admissions.
Family History: Maternal uncle has a history of mental illness (unspecified).
Personal/Social History: Stopped college in 2nd year after first psychotic break. Smokes 5–10 cigarettes per day. No alcohol or illicit drug use. Premorbid functioning was described as shy but functional.
Mental Status Examination (MSE) Findings
| Domain | Findings |
|---|
| General Appearance | Disheveled, poorly groomed, wearing soiled clothes, appears older than stated age, guarded posture |
| Level of Consciousness | Alert but hypervigilant |
| Behavior/Psychomotor Activity | Restless, pacing, occasionally stops to look around; poor eye contact |
| Attitude Toward Examiner | Guarded, suspicious, uncooperative at times |
| Speech | Loud, pressured at times; with loosening of associations; occasional echolalia |
| Mood | Dysphoric — "Natatakot ako. Gusto nilang patayin ako." (I'm scared. They want to kill me.) |
| Affect | Flat with occasional bursts of agitation; mood-incongruent |
| Thought Process | Disorganized; loose associations; circumstantiality; tangentiality |
| Thought Content | Persecutory delusions ("neighbors are poisoning my food, people want to kill me"); ideas of reference (believes TV is sending him messages) |
| Perceptual Disturbances | Auditory hallucinations — hears 2–3 male voices commenting on his actions and issuing commands; denies visual hallucinations |
| Insight | Poor — denies he is ill; believes the hospital is part of a conspiracy |
| Judgment | Impaired |
| Memory | Immediate and short-term intact; remote memory intact |
| Intelligence | Average based on premorbid functioning |
| Concentration | Impaired; easily distracted by internal stimuli |
3. PHYSICAL EXAMINATION FINDINGS
(Findings only, relevant to age group — 24-year-old young adult male)
General Survey: Alert, ambulatory, poorly nourished, appears chronically ill
Vital Signs:
- BP: 110/70 mmHg
- HR: 98 bpm (tachycardic — likely anxiety/agitation)
- RR: 20 cpm
- Temp: 36.8°C
- O2 Sat: 99% room air
- Weight: 52 kg | Height: 5'7" | BMI: 18.1 kg/m² (underweight — consistent with poor self-care and food refusal)
Skin: Dry, with mild excoriations on forearms (self-scratching); poor skin turgor
Head/Neck: Normocephalic; no lymphadenopathy; no neck rigidity
Eyes: Pupils equal and reactive to light; no nystagmus; poor eye contact
Mouth/Oral: Dry mucous membranes; halitosis; poor dental hygiene
Chest/Lungs: Clear to auscultation bilaterally
Cardiovascular: Regular rate and rhythm; no murmurs
Abdomen: Soft, non-tender; hypoactive bowel sounds (likely due to poor oral intake)
Extremities: No edema; mild tremors noted on both hands (neurological soft sign — common in untreated schizophrenia)
Neurological: Motor rigidity mild; neurological soft signs present (minor tremors, poor coordination on fine motor tasks); no frank focal neurological deficits
Comparison to book: According to Harrison's Principles of Internal Medicine 22E, "The general neurologic examination in patients with schizophrenia is usually normal, but motor rigidity, tremor, and dyskinesias are noted in one-quarter of untreated patients." Consistent with Mr. R.C.'s findings.
4. DEVELOPMENTAL TASK — Related to Age Group, Compared to Book
Patient's Age Group: 24 years old — Young Adulthood (18–40 years)
According to Erik Erikson's Psychosocial Developmental Theory, the task for young adulthood (ages 18–40) is:
Stage 6: Intimacy vs. Isolation
The developmental goal is to form meaningful, deep, committed relationships with others — romantic, social, and professional. Successful resolution results in the capacity for love and closeness; failure results in isolation, loneliness, and social withdrawal.
Application to Mr. R.C.:
| Erikson's Expected Task | Mr. R.C.'s Actual Status |
|---|
| Forming intimate relationships / romantic partner | Single; no romantic relationships; socially isolated |
| Maintaining friendships and social bonds | No close friends; withdrew from peers after first psychotic break |
| Establishing career identity and independence | Unemployed; dropped out of college; fully dependent on mother |
| Developing sense of identity continuity | Disrupted by onset of schizophrenia at age 21 |
Conclusion: Mr. R.C. is failing to meet the developmental task of Intimacy vs. Isolation. The onset of schizophrenia in late adolescence/early adulthood directly disrupted his capacity to form relationships, pursue education, and build identity — a pattern well-documented in schizophrenia, where "peak onset is in late adolescence to young adulthood" (Goldman-Cecil Medicine). His condition has resulted in profound social isolation, the negative pole of Erikson's Stage 6.
According to Harrison's 22E, "Schizophrenia commonly begins in late adolescence, has an insidious onset, and, often, a poor outcome, progressing from social withdrawal and perceptual distortions to recurrent delusions and hallucinations." This directly explains why Mr. R.C. cannot accomplish his developmental tasks.
5. DISEASE PROFILE — In Detail (Incidence/Prevalence, Compare to Book)
Definition
Schizophrenia is a chronic, severe, heterogeneous psychiatric syndrome characterized by disturbances in perception, cognition, emotion, language, sense of self, and behavior. It includes positive symptoms (hallucinations, delusions, disorganized speech and behavior) and negative symptoms (flat affect, alogia, avolition, anhedonia, social withdrawal).
DSM-5 Diagnostic Criteria:
Two or more of the following, each present for a significant portion of time during a 1-month period, with at least one being (1), (2), or (3):
- Delusions
- Hallucinations
- Disorganized speech
- Grossly disorganized or catatonic behavior
- Negative symptoms
Plus: Continuous signs of disturbance for at least 6 months and significant functional decline.
Incidence and Prevalence
| Epidemiologic Measure | Data |
|---|
| Lifetime Prevalence (Global) | ~0.85% – 1% of the world population |
| Annual Incidence (US) | ~15 per 100,000 persons per year |
| Annual Acute Episodes (US) | ~300,000 episodes per year |
| Economic Burden (US) | Direct and indirect costs: $155.7 billion |
| Sex Difference | Slightly more common in males; earlier onset in males (early 20s) vs. females (late 20s) |
| Genetic Risk — 1st degree relatives | ~6.6% |
| Risk — both parents affected | 40% |
| Monozygotic twin concordance | 50% |
| Dizygotic twin concordance | 10% |
| Suicide risk | ~10% of patients commit suicide |
Source: Harrison's Principles of Internal Medicine 22E — "Schizophrenia is present in 0.85% of individuals worldwide, with a lifetime prevalence of ~1–1.5%. An estimated 300,000 episodes of acute schizophrenia occur annually in the United States, resulting in direct and indirect costs of $155.7 billion."
Goldman-Cecil Medicine — "The annual incidence is approximately 15 per 100,000, but with marked variability across study samples and populations."
Etiology and Risk Factors
1. Genetic Factors
- Multiple gene loci involved; large-scale GWAS studies identified hundreds of small-effect risk loci
- Pathways implicated: immunity, inflammation, cell signaling, synaptic plasticity
2. Neurodevelopmental Factors
- Early developmental insults (prenatal infections, obstetric complications, nutritional deficiencies)
- Brain gene expression in schizophrenia parallels aging brain changes, suggesting accelerated neurodegeneration
3. Neurobiological Factors
- Dopamine hypothesis: Hyperactivity of dopaminergic mesolimbic pathways → positive symptoms
- Glutamate hypothesis: Hypofunction of NMDA receptors → both positive and negative symptoms
- Subtle cortical cytoarchitectural disruptions in post-mortem brain studies; nongliotic process
4. Psychosocial Factors
- Urbanicity, migration, childhood trauma, cannabis use, increasing paternal age, winter birth
- Psychosocial stressors precipitate exacerbations
Types of Schizophrenia (DSM-IV subtyping — still clinically referenced)
| Subtype | Key Feature |
|---|
| Paranoid | Prominent delusions/hallucinations, organized thinking, less negative symptoms |
| Disorganized (Hebephrenic) | Disorganized speech/behavior, flat/inappropriate affect, no organized delusions |
| Catatonic | Catatonia dominant: stupor, mutism, waxy flexibility, stereotypy |
| Undifferentiated | Criteria met but doesn't fit paranoid, disorganized, or catatonic |
| Residual | No current positive symptoms; negative symptoms remain |
Mr. R.C. presents with the Paranoid subtype — prominent persecutory delusions and auditory hallucinations with relatively organized thought at times.
Symptoms Summary
Positive Symptoms:
- Hallucinations (auditory most common)
- Delusions (persecutory, referential)
- Disorganized speech (loose associations, tangentiality, word salad)
- Grossly disorganized or catatonic behavior
Negative Symptoms:
- Flat affect
- Alogia (poverty of speech)
- Avolition (inability to initiate goal-directed activity)
- Anhedonia
- Asociality
Harrison's 22E: "Negative symptoms predominate in one-third of the schizophrenic population and are associated with a poor long-term outcome and a poor response to drug treatment."
Prognosis
- Rule of thirds: ⅓ improve significantly, ⅓ remain chronically ill with partial function, ⅓ are severely and persistently impaired
- Poor prognostic factors: male sex, insidious onset, early age of onset, prominent negative symptoms, medication non-compliance, lack of social support, substance use
- About 10% commit suicide (Harrison's 22E)
6. NURSING THEORY APPLICATION — In Short
Hildegard Peplau's Theory of Interpersonal Relations
Application to Mr. R.C.:
Peplau's theory centers on the therapeutic nurse-patient relationship as a healing force. There are four overlapping phases:
| Phase | Application |
|---|
| Orientation | Nurse introduces herself, establishes trust; Mr. R.C. is highly suspicious — use calm, consistent, non-threatening approach; avoid touching without permission; keep voice low and steady |
| Identification | Patient begins to identify the nurse as a helping person; nurse identifies his fears (persecution, poisoning) without reinforcing delusions |
| Exploitation | Patient uses the nurse-patient relationship to meet his needs; nurse provides therapeutic communication, reality orientation, and emotional support |
| Resolution | Patient becomes independent, internalizes coping strategies, prepares for discharge |
Why Peplau? Schizophrenia fundamentally disrupts interpersonal relationships. Peplau's theory directly targets relationship building as the vehicle of nursing care — particularly relevant for a patient with paranoid features and profound social isolation.
7. NURSING DIAGNOSES — Only (No Care Plan)
(5 diagnoses: 3 Psychological, 1 Physical, 1 Potential)
Psychological Diagnoses (3):
-
Disturbed Sensory Perception (Auditory) related to neurobiological alterations as evidenced by reports of hearing voices commanding and commenting on actions, hypervigilance, and responding to internal stimuli.
-
Disturbed Thought Processes related to biochemical imbalances (dopaminergic hyperactivity) as evidenced by persecutory delusions, ideas of reference, loose associations, and impaired judgment.
-
Social Isolation related to inability to engage in satisfying personal relationships secondary to paranoid ideation and negative symptoms, as evidenced by withdrawal, lack of friends, and refusal to interact with other patients.
Physical Diagnosis (1):
- Imbalanced Nutrition: Less Than Body Requirements related to refusal to eat secondary to persecutory delusions about food being poisoned, as evidenced by BMI of 18.1 kg/m² (underweight), dry mucous membranes, and reported 3-day refusal to eat.
Potential (Risk) Diagnosis (1):
- Risk for Other-Directed Violence related to command hallucinations, paranoid delusions, and history of carrying a weapon, as evidenced by admission incident involving a kitchen knife and belief that others intend to harm him.
8. DRUGS USED IN PATIENT — List
| Drug | Classification | Dose/Route | Indication |
|---|
| Risperidone (Risperdal) | 2nd-Generation (Atypical) Antipsychotic — D2/5-HT2A antagonist | 2 mg PO BID | Positive and negative symptoms of schizophrenia |
| Haloperidol (Haldol) | 1st-Generation (Typical) Antipsychotic — D2 antagonist | 5 mg IM PRN | Acute agitation; used during acute psychotic episode in ward |
| Lorazepam (Ativan) | Benzodiazepine | 1–2 mg IM/IV PRN | Adjunct for acute agitation; reduces anxiety and prevents violence |
| Biperiden (Akineton) | Anticholinergic (Antiparkinson) | 2 mg PO OD | Prevention/treatment of extrapyramidal side effects (EPS) from haloperidol |
| Clonazepam (Rivotril) | Benzodiazepine | 0.5 mg PO BID | Adjunct anxiolytic; sleep regulation |
Drug Notes:
- Risperidone is the maintenance antipsychotic; the most important drug to re-establish compliance
- Haloperidol used only PRN for acute agitation — short-term
- Biperiden is co-prescribed to prevent EPS (dystonia, akathisia, rigidity) from haloperidol
- Monitor for metabolic syndrome (weight gain, glucose, lipids) with atypical antipsychotics
- Monitor CBC regularly if clozapine is ever considered (risk of agranulocytosis)
Harrison's 22E: "Antipsychotic agents are the cornerstone of acute and maintenance treatment of schizophrenia... Second-generation atypical antipsychotic medications have replaced first-generation antipsychotics in common practice because of their lower rates of extrapyramidal side effects."
9. HEALTH TEACHING — Focus on Key Points
(Directed to patient and family/caregiver — mother)
Key Points Only:
-
Medication Compliance is Non-Negotiable
- "Do not stop taking Risperidone even when you feel better. Stopping medicines is the number one cause of relapse."
- Teach mother to supervise medication intake daily; use pill organizer
-
Recognize Early Warning Signs of Relapse
- Increased suspiciousness or fearfulness
- Sleep disturbances (insomnia or sleeping too much)
- Social withdrawal worsening
- Talking to self / responding to unseen stimuli
- → "If these occur, bring him to the psychiatrist immediately — do not wait."
-
Trigger Management
- Reduce psychosocial stressors at home
- Avoid cannabis and alcohol — these precipitate psychotic episodes
- Maintain structured daily routine
-
Coping with Hallucinations
- Teach patient: "When you hear voices, remind yourself — these are symptoms of your illness, not real threats."
- Distraction techniques: music, walking, deep breathing
-
Family Expressed Emotion (EE) Reduction
- Avoid criticizing or shouting at the patient — high EE in family doubles relapse risk
- Speak calmly, give simple instructions
10. DISCHARGE TEACHING — Focus on Key Points
(Planning begins on admission — teach from Day 1)
-
Follow-up Schedule
- Return to OPD psychiatry clinic in 2 weeks after discharge
- Never miss a follow-up; bring all medications
-
Medication Instructions at Home
- Continue Risperidone 2mg BID exactly as prescribed
- Do not self-adjust dose
- Report side effects: restlessness, stiffness, involuntary movements → contact doctor immediately
-
Diet and Nutrition
- Eat small, frequent meals; high-protein, high-calorie diet to address underweight status
- Engage him in meal preparation so he feels in control — reduces paranoia about food
-
Activity Restrictions
- No driving or operating machinery while on antipsychotics and benzodiazepines
- No alcohol
-
Emergency Action Plan
- If patient becomes violent, refuses all food/water, or attempts self-harm → bring to nearest ER immediately
- National mental health hotline: 1553 (DOH Philippines)
-
Community Support
- Refer to community mental health program
- Link with Barangay Health Center for home visits and medicine supply
11. DIVERSIONAL THERAPY
Diversional therapy aims to reduce the patient's preoccupation with hallucinations and delusions by engaging him in structured, meaningful, and enjoyable activities that promote reality orientation and social interaction.
Activities Appropriate for Mr. R.C.:
| Activity | Rationale |
|---|
| Drawing / Coloring | Non-threatening creative outlet; promotes focus; reduces internal stimuli preoccupation |
| Music Therapy | Headphones with calming music reduces auditory hallucination intensity; evidence-based adjunct |
| Occupational Therapy — Weaving, Beading | Promotes fine motor skills, concentration, and sense of accomplishment |
| Group Games (Bingo, Cards) | Gradual re-introduction to social interaction in a structured, supervised setting |
| Light Exercise / Morning Walk | Physical activity reduces anxiety; improves sleep; dopamine regulation |
| Reality Orientation Group | Daily group session oriented to date, place, current events; reduces confusion and delusions |
Nursing Role:
- Introduce activities gradually — never force
- Praise participation, not just output
- Use activities as opportunity for therapeutic communication
12. DAILY PROGRESS NOTE
Date: May 8, 2026 (Day 3 of Admission)
S (Subjective): "Hindi ako baliw. Pero okay na 'yung pagkain ngayon." ("I'm not crazy. But the food is okay now.")
O (Objective):
- Ate 60% of breakfast for the first time since admission
- Vital signs stable: BP 118/74, HR 88, RR 18, Temp 36.6°C
- Less pacing observed; sat in group area for 15 minutes
- Still responding to internal stimuli occasionally (talking to self 2x observed)
- Sleep: 5 hours (improved from 2 hours on Day 1)
- Haloperidol PRN not given today (no acute agitation)
- Risperidone 2mg BID given and taken with supervision
A (Assessment):
- Partial improvement in agitation and food intake
- Auditory hallucinations persisting but patient beginning to tolerate therapeutic setting
- Paranoia slightly reduced — accepting food from nurse
- Nutritional deficit still a concern (BMI 18.1)
- Insight remains poor
P (Plan):
- Continue Risperidone 2mg BID; monitor for EPS
- Encourage intake at every meal; document percentage eaten
- Introduce first diversional activity (coloring) today
- Begin health teaching with mother this afternoon
- Continue close observation for safety (Risk for Violence — still priority)
- Psychiatric rounds tomorrow with Dr. Santos
13. SUMMARY — Short
Mr. R.C. is a 24-year-old single Filipino male admitted for the third time with acute relapse of schizophrenia, paranoid type, secondary to medication non-compliance. He presents with prominent positive symptoms including auditory command hallucinations, persecutory delusions, and disorganized behavior, as well as negative symptoms of flat affect and social withdrawal. Physical examination reveals underweight status and neurological soft signs. He is failing to meet his developmental task of Intimacy vs. Isolation per Erikson's theory, largely due to the early onset and chronic course of his illness.
Nursing care is guided by Peplau's Interpersonal Relations Theory, emphasizing the therapeutic relationship. Priority nursing diagnoses include disturbed sensory perception, disturbed thought processes, imbalanced nutrition, social isolation, and risk for violence. Current pharmacological management involves Risperidone as maintenance, with PRN Haloperidol for agitation and Biperiden for EPS prevention. Nursing interventions focus on safety, medication compliance, nutritional support, and gradual social reintegration. Health and discharge teaching targets the family and patient on medication adherence, relapse warning signs, and follow-up care.
14. BIBLIOGRAPHY — At Least 5
-
Jameson, J.L., et al. (2025). Harrison's Principles of Internal Medicine (22nd ed.). McGraw-Hill Medical. — Schizophrenia: Clinical Manifestations, Epidemiology, Treatment, pp. 3714–3718.
-
Goldman, L., & Cooney, K.A. (Eds.). (2024). Goldman-Cecil Medicine International Edition (27th ed.). Elsevier. — Schizophrenia: Definition, Epidemiology, Diagnosis, Treatment, pp. 2488–2514.
-
Sadock, B.J., Sadock, V.A., & Ruiz, P. (Eds.). (2022). Kaplan & Sadock's Synopsis of Psychiatry (12th ed.). Wolters Kluwer. — Schizophrenia Spectrum Disorders; Mental Status Examination.
-
Sadock, B.J. (2022). Kaplan & Sadock's Comprehensive Textbook of Psychiatry (11th ed.). Wolters Kluwer. — Epidemiology and pathogenesis of schizophrenia.
-
Townsend, M.C., & Morgan, K.I. (2021). Psychiatric Mental Health Nursing: Concepts of Care in Evidence-Based Practice (9th ed.). F.A. Davis. — Nursing diagnoses and care for schizophrenia; Peplau's interpersonal theory.
-
Philippine Psychiatric Association. (2022). Clinical Practice Guidelines for the Management of Schizophrenia in the Philippines. PPA.
-
Department of Health Philippines. (2023).
National Mental Health Program. Republic of the Philippines, DOH. Retrieved from
https://www.doh.gov.ph
Presenter's Note: This case is based on a hypothetical patient constructed to meet all criteria for clinical case study presentation. All data — demographic, clinical, and pharmacological — reflect current evidence-based practice and textbook standards as cited above. Good morning/afternoon, panel. I am ready to take your questions.
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