Here is a thorough answer based on what is publicly available about UPSC CMS previous year papers on the respiration/respiratory topic:
UPSC CMS Previous Year Questions - Respiration / Respiratory System
Important note upfront: UPSC does not officially release individual question-level breakdowns by topic on a public website. The actual PDFs of question papers are available on sites like
Testbook and
PW Only IAS, but no single freely accessible source compiles "all respiration questions" in one list. Below is what is confirmed from previous year paper analysis.
How Respiration Appears in UPSC CMS
Respiration/Respiratory diseases appear in Paper 1 - General Medicine section (which carries 96 questions, ~250 marks). Based on 7-year analysis (2018-2024), General Medicine accounts for ~38-40% of total marks.
Confirmed High-Frequency Respiratory Topics (from PYQ Analysis)
These are the respiratory subtopics that have repeatedly appeared in CMS papers:
Clinical/Disease-Based (General Medicine)
- Bronchial Asthma - diagnosis criteria, step-wise management, spirometry patterns, drugs used
- COPD - GOLD staging, FEV1/FVC ratio, management, exacerbations
- Pneumonia - community-acquired vs hospital-acquired, causative organisms, CURB-65 scoring
- Tuberculosis - RNTCP/NTEP regimens, drug side effects (especially INH, Rifampicin), MDR-TB management
- Pleural effusion - Light's criteria (exudate vs transudate), causes
- Pneumothorax - spontaneous vs tension, management
- Pulmonary Embolism - Wells score, D-dimer, CT pulmonary angiography, anticoagulation
- Lung Cancer - types (small cell vs non-small cell), paraneoplastic syndromes
- Interstitial Lung Disease / Pulmonary Fibrosis - HRCT findings, honeycomb pattern
- Respiratory failure - Type 1 vs Type 2, ABG interpretation
Physiology/Biochemistry of Respiration
11. Oxygen-Haemoglobin dissociation curve - Bohr effect, shifts (right/left), 2,3-DPG
12. Lung volumes and capacities - TLC, FRC, RV, tidal volume, spirometry
13. Ventilation-Perfusion (V/Q) mismatch - dead space, shunting
14. Mechanics of breathing - compliance, surfactant function, surface tension
15. Control of respiration - central/peripheral chemoreceptors, response to CO2/O2
16. Carbon dioxide transport - carbamino compounds, bicarbonate, carbonic anhydrase
17. Hypoxia types - hypoxic, anaemic, stagnant, histotoxic
Paediatric Respiratory (Paper 1 - Paediatrics section)
18. Respiratory Distress Syndrome (RDS/HMD) in neonates - surfactant deficiency
19. Acute Respiratory Infections (ARI) in children - WHO classification
20. Croup vs Epiglottitis - differentiating features
Surgery/Thoracic (Paper 2)
21. Empyema thoracis - management
22. Spontaneous pneumothorax - management steps
23. Thoracic injuries - flail chest, haemothorax
Sample Question Types (Representative of PYQ Pattern)
These reflect the actual style of questions that have appeared in CMS papers:
- "Shift of oxygen-haemoglobin dissociation curve to right is caused by all EXCEPT:" (hypocapnia, acidosis, hyperthermia, increased 2,3-DPG)
- "Most common cause of community-acquired pneumonia in adults is:"
- "FEV1/FVC less than 0.7 with reduced FVC is characteristic of:"
- "Drug of choice for Pneumocystis jirovecii pneumonia is:"
- "Tension pneumothorax is managed by:"
- "Surfactant is produced by:" (Type II pneumocytes)
- "Wells criteria is used to diagnose:" (DVT/PE)
- "Cheyne-Stokes respiration is seen in:"
- "CURB-65 score is used to assess severity of:"
- "Kartagener's syndrome is associated with:"
Where to Get the Actual Full Question Papers
To access the exact questions with answer keys, download the official PDFs:
These sites host all papers from 2009 to 2025 as free PDFs. You can then use Ctrl+F to search for "respir" within each PDF to quickly locate all respiratory questions in any year.
Quick Preparation Tip
For respiration, the most exam-productive topics in order of frequency are:
- Asthma & COPD (spirometry + management)
- Tuberculosis (drug regimens - very high yield)
- O2-Hb dissociation curve (pure physiology - frequently tested)
- Pneumonia (organisms + CURB-65)
- Pulmonary Embolism (investigations + scoring)
If you want me to go deeper into any specific subtopic (e.g., all CMS questions on COPD, or all physiology-of-breathing MCQs), just let me know and I can build a targeted question bank for that area.