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HIV in Pregnancy - Model Answer (3+3 marks)

Part (a): Public Health Measures to Prevent Mother-to-Child Transmission (3 marks)

Mother-to-child (vertical) transmission of HIV can occur during pregnancy, labour/delivery, and breastfeeding. India's PPTCT (Prevention of Parent-to-Child Transmission) programme under NACP provides the following public health measures:

1. Universal HIV Screening in Antenatal Care

  • Routine HIV counselling and testing is offered to all pregnant women at ICTCs (Integrated Counselling and Testing Centres) with an "opt-out" option.
  • Involvement of spouse and family members - a shift from "ANC-centric" to a "Family-Centric" approach.

2. Lifelong ART for All HIV-Positive Pregnant Women

  • Provision of lifelong triple-drug ART (TDF + 3TC + EFV) to all HIV-positive pregnant and breastfeeding women, regardless of CD4 count or clinical stage (Option B+).
  • This replaced earlier single-dose Nevirapine (SD-NVP) strategy.

3. Safe Delivery Practices

  • Promotion of institutional deliveries for all HIV-positive pregnant women to reduce intrapartum transmission risk.

4. ARV Prophylaxis to Newborn

  • Provision of ARV prophylaxis to infants from birth up to a minimum of 6 weeks (extended to 6 months).

5. Infant Feeding Counselling

  • Counselling and support for exclusive breastfeeding within one hour of delivery as the preferred option, continued for 6 months (rather than mixed feeding, which increases risk).

6. Early Infant Diagnosis (EID)

  • Initiation of Co-trimoxazole Prophylactic Therapy (CPT) and HIV-DNA PCR at 6 weeks of age onwards for HIV-exposed infants.
  • Integration of follow-up of HIV-exposed infants into routine immunization services.

7. Management of Co-infections

  • Provision of care for associated conditions - STIs, RTIs, tuberculosis, and other opportunistic infections.
  • Provision of nutrition counselling and psychosocial support for HIV-positive pregnant women.

8. Community Outreach

  • Strengthening community follow-up through local networks to support HIV-positive pregnant women and their families.

Part (b): Role of National AIDS Control Programme (NACP) in Management (3 marks)

NACP was launched in 1987; the National AIDS Control Organization (NACO) was set up under the Ministry of Health and Family Welfare to implement it. The current framework operates under the National Strategic Plan for HIV/AIDS and STIs (2017-2025).

Key Roles of NACP:

1. Surveillance
  • HIV Sentinel Surveillance at antenatal clinics (ANC) and high-risk group sites every 2 years, to track epidemic trends and allocate resources.
  • Categories of districts (A-D) based on HIV prevalence to prioritize interventions.
2. Testing & Counselling (ICTC Network)
  • More than 15,000 ICTCs across the country offer PPTCT services.
  • Facility-level, standalone, and community-based HIV testing at multiple tiers (village to state level).
3. Targeted Interventions (TI)
  • Outreach programmes for high-risk groups (FSWs, IDUs, MSM, transgender persons) and bridge populations (truckers, migrants).
4. Care, Support & Treatment (ART Programme)
  • Free, universal, lifelong standardized ART through ART centres, Centres of Excellence (CoE), and ART-Plus centres.
  • First-line, second-line, and third-line ART available (third-line includes Raltegravir + Darunavir).
  • CD4 testing and viral load monitoring every 6 months free of charge.
  • Management of opportunistic infections (OIs) at ART centres.
5. PPTCT Programme
  • Integration of PPTCT services with the existing Reproductive and Child Health (RCH) programme.
  • National target: MTCT rate <5% and <50 new paediatric HIV infections per 100,000 live births.
6. TB-HIV Co-ordination
  • Joint strategy with RNTCP: offering HIV testing to all diagnosed TB patients and TB screening among PLHIV.
  • Isoniazid Prophylaxis Therapy (IPT) for PLHIV to prevent TB.
7. Paediatric HIV Initiative
  • National Paediatric HIV/AIDS Initiative (launched 2006) - free ART and paediatric ARV formulations at all ART centres.
  • Early Infant Diagnosis (EID) programme - HIV-DNA PCR for confirmation, linkage to ART.
8. IEC (Information, Education, Communication)
  • Adolescence Education Programme in schools (class IX and XI, 16-hour sessions).
  • Red Ribbon Clubs in colleges for peer-to-peer HIV prevention messaging.
  • Communication targeted at general population, high-risk groups, and anti-stigma initiatives.
9. Financing & Sustainability
  • NSP 2017-25 commits to 100% domestic funding for key NACP components: prevention outreach, testing, treatment, PMTCT, viral load suppression, care and support.

Source: Park's Textbook of Preventive and Social Medicine, NACP section, pp. 488-498
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