Section 7, miscellaneous bacterial infections, 179 chapter nocardia is 180 at mycosis, 181 peoples disease, 182 infections due to mixed aerobic organisms. Section 8 micro bacterial diseases chapter number 183, tuberculosis 184 x 185 non-tuberculous bacterial infections, 186 antimicrobial anti Mico bacterial agents, section 9, Phairo diseases, 187, syphilis 188, hematosis 189 la pyrosis, 190 lapsing fever, 191 lines disease section 10 disease is caused by cricket, CA micro plasma and club idea. Chapter number 192 cricket CL is 193 infections due to mycoplasma 194 loml disease section number 11 viral diseases, general considerations, 195 principles of medical virology, 196 anti-viral haemotherapy, excluding antiretroviral drugs. These are the chapters from Harrisons 22nd edition teach me in detail about these topics.
What Was Covered - All 18 Chapters from Harrison's 22E
- Ch. 179 Nocardia - weakly acid-fast opportunist; TMP-SMX treatment; triple therapy for disseminated/CNS disease
- Ch. 180 Actinomycosis - "most misdiagnosed disease"; sulfur granules; prolonged penicillin G
- Ch. 181 Leprosy - M. leprae; Ridley-Jopling classification; WHO MDT (rifampicin + dapsone ± clofazimine)
- Ch. 182 Mixed Aerobic/Anaerobic - source control paramount; Bacteroides fragilis; metronidazole/carbapenems
- Ch. 183 Tuberculosis - top infectious killer 2023; HRZE x 2 months → HR x 4 months; MDR-TB BPaL regimen
- Ch. 185 NTM - >199 species; MAC commonest; macrolide + ethambutol + rifampicin
- Ch. 186 Antimycobacterial Agents - all first- and second-line drugs with mechanisms and side effects
- Ch. 187 Syphilis - stages (primary/secondary/latent/tertiary/neurosyphilis); VDRL then FTA-ABS; benzathine penicillin G
- Ch. 188 Endemic Treponematoses - yaws, bejel, pinta; azithromycin
- Ch. 189 Leptospirosis - Weil's disease triad; MAT serology; doxycycline vs. penicillin IV
- Ch. 190 Relapsing Fever - antigenic variation; spirochetes on blood smear; Jarisch-Herxheimer reaction
- Ch. 191 Lyme Disease - erythema migrans; two-tier serology; doxycycline vs. ceftriaxone IV
- Ch. 192 Rickettsial Diseases - RMSF, typhus, scrub typhus, Q fever, ehrlichiosis, anaplasmosis; doxycycline is universal treatment
- Ch. 193 Mycoplasmas - no cell wall; M. pneumoniae walking pneumonia; cold agglutinins; macrolides
- Ch. 194 Chlamydial Diseases - EB/RB life cycle; trachoma (A-C), urogenital (D-K), LGV (L1-L3); NAATdiagnosis; doxycycline
- Ch. 195 Principles of Medical Virology - structure, genome types, replication cycle, vaccines, viruses as therapeutics
- Ch. 196 Antiviral Chemotherapy - antiherpesviral drugs (acyclovir, ganciclovir, foscarnet), antiinfluenza (neuraminidase inhibitors, baloxavir), hepatitis B analogs, HCV DAA regimens (sofosbuvir-based)