# -*- coding: utf-8 -*-
from docx import Document
from docx.shared import Pt, Inches, RGBColor
from docx.enum.text import WD_ALIGN_PARAGRAPH
from docx.enum.table import WD_TABLE_ALIGNMENT
from docx.oxml.ns import qn
from docx.oxml import OxmlElement

doc = Document()
style = doc.styles["Normal"]
style.font.name = "Calibri"
style.font.size = Pt(10.5)

def set_col_widths(table, widths):
    for row in table.rows:
        for idx, w in enumerate(widths):
            row.cells[idx].width = w

def shade_cell(cell, color_hex):
    tc_pr = cell._tc.get_or_add_tcPr()
    shd = OxmlElement('w:shd')
    shd.set(qn('w:val'), 'clear')
    shd.set(qn('w:color'), 'auto')
    shd.set(qn('w:fill'), color_hex)
    tc_pr.append(shd)

# ---------------- TITLE PAGE ----------------
title = doc.add_heading("MD (Dermatology, Venereology & Leprosy)", level=0)
title.alignment = WD_ALIGN_PARAGRAPH.CENTER
sub = doc.add_heading("Final Examination Question Bank & High-Yield Analysis (2015 - 2025)", level=2)
sub.alignment = WD_ALIGN_PARAGRAPH.CENTER
p = doc.add_paragraph("Compiled from 11 examination sessions (July-2015 through November-2025), covering Paper I-IV.")
p.alignment = WD_ALIGN_PARAGRAPH.CENTER
p2 = doc.add_paragraph("Source: scanned university question papers (Final year Ques paper 2015-2025.pdf), transcribed and organised for revision.")
p2.alignment = WD_ALIGN_PARAGRAPH.CENTER
doc.add_page_break()

# ---------------- DATA ----------------
# Each paper category -> list of (session, questions dict)
papers = {
"PAPER I - Basic Sciences as related to Dermatology, Venereology and Leprosy": [
 ("July-2015", ["What is Melanin? Discuss ultrastructure of melanocyte and melanogenesis in detail. Discuss racial differences in skin colour.",
  "Discuss structure and components of cutaneous immune system. Describe ultrastructure of Langerhans cells and its role in cutaneous inflammation.",
  "Describe Sebaceous Gland, its structure and distribution. Describe composition of sebum. Discuss functions of sebaceous gland with respect to age.",
  "Basic principles of cutaneous photobiology. Discuss normal and abnormal cutaneous effects of UV ray exposure. Describe skin photo types.",
  "Short notes: Immunofluorescence in Dermatology; Z.N. Stain; Prenatal Diagnosis in Dermatology."]),
 ("April-2016", ["Describe structure and functions of Pilosebaceous Unit.",
  "Discuss pathogenesis of Acne.",
  "Pulse therapy in Dermatology.",
  "Pruritus.",
  "Short notes: Phytophotodermatitis; Mast Cell degranulators; Uses of Dapsone."]),
 ("April-2017", ["What is Follicular Unit? Discuss hair cycle in detail. Describe morphology of terminal hair with labelled diagram.",
  "Define Interface Dermatitis. Discuss differential diagnosis.",
  "Dermatoscopy.",
  "Fillers in Dermatology.",
  "Short notes: Toll Like Receptors; Pathogenesis of Reactions in Leprosy; Treponema Pallidum."]),
 ("April-2018", ["Describe physiological cutaneous reaction to cold. Enumerate diseases caused/aggravated by cold. Discuss Raynaud's phenomenon.",
  "Describe dynamics of epidermal cell cycle and control of epidermopoiesis.",
  "Discuss functions of skin. What is skin failure? Describe causes of skin failure.",
  "Discuss skin as a defense organ.",
  "Short notes: Dermo-epidermal junction; Cytokines in dermatology; Cutaneous microbial flora."]),
 ("April-2019", ["Discuss pathophysiology of pruritus. Enumerate mediators of pruritus. Classify antihistamines.",
  "Discuss cutaneous photobiology, interaction of UV radiation with skin (normal/abnormal effects). Prophylactic measures against UV exposure.",
  "Discuss antenatal diagnostic tests in dermatology. Discuss genetic mosaicism.",
  "Discuss DLQI and its applications.",
  "Short notes: Cytodiagnosis in dermatology; Superantigen; Resident flora of skin."]),
 ("June-2020", ["Describe structure and histology of eccrine sweat gland, formation/composition of sweat, nerve supply.",
  "Difference between eccrine and apocrine glands. Discuss skin in neonates and old age.",
  "Different skin biopsy techniques; special stains used; diseases needing special stains.",
  "Dendritic cells in skin.",
  "Short notes: Innate and acquired immunity (diagnostic implications); Histopathology of syringoma; Annual case detection rate in leprosy vs prevalence rate / randomization in studies."]),
 ("June-2021", ["What is immunofluorescence study? Principle & patterns in dermatological disorders. Limitations of DIF/IIF.",
  "Describe anatomy of hair (diagram at level of Adamson's fringe). Phases of hair cycle. Methods of microscopic hair examination.",
  "Functions of skin. Discuss acute skin failure.",
  "Melanocytes and melanogenesis. Etiological classification of amelanotic/hypomelanotic disorders.",
  "Short notes: Slit skin smear technique & Ridley-Jopling scale; Sensory receptors of skin; Somatic mosaicism."]),
 ("November-2022", ["Structural/ultrastructural features of eccrine sweat gland, mechanism of sweat secretion, composition. Causes of hyperhidrosis.",
  "Types of hypersensitivity reactions. Dermatological conditions related to Type I & Type II hypersensitivity.",
  "Collagen tissue in dermis; related dermatological diseases; chronologic vs photo-aged skin.",
  "Regional variations in skin. Functions of skin.",
  "Short notes: Stages of wound healing & PRF therapy; Commensals on skin/mucous membranes; Interface dermatitis vs lichenoid drug reaction."]),
 ("July-2023", ["Structure of Pilosebaceous unit (diagram). Hidradenitis suppurativa in detail.",
  "Applied anatomy of epidermal melanin unit. Melanogenesis and disorders of defective melanogenesis. Pathogenesis of vitiligo & pulse therapy.",
  "Special stains in Dermatology.",
  "Histopathology of Hailey-Hailey disease.",
  "Short notes: Skin as endocrine target; Types of skin biopsy techniques; Sclerotherapy in Dermatology."]),
 ("January-2025", ["Describe process of Keratinization. Enumerate keratinization disorders.",
  "Discuss normal/abnormal cutaneous reaction to heat and cold. Raynaud's Phenomenon.",
  "Serological tests for syphilis.",
  "Thermoregulation of skin and applied importance.",
  "Short notes: Structure of nail; Langerhans cells; Intradermal tests in dermatology."]),
 ("November-2025", ["Describe structure of nail and diseases affecting nail. Different nail signs.",
  "Structure & ultrastructure of Dermoepidermal Junction. Diseases affecting DEJ.",
  "Describe phototherapy and photochemotherapy.",
  "Cutaneous photobiology and interaction of UV light with skin; positive/negative effects of UV.",
  "Short notes: Giant cells in dermatology; Resident microflora; Histopathology of Lichen Planus."]),
],
"PAPER II - Principle and Practice of Dermatology": [
 ("July-2015", ["Describe pathogenesis of Psoriasis and role of biologicals in management.",
  "Describe pathophysiology of pruritus; approach to a 55-year-old male with generalized pruritus.",
  "Cutaneous manifestations of diabetes mellitus.",
  "Classify psychocutaneous disorders and management.",
  "Short notes: Tuberculides; Scleredema; Acrodermatitis Enteropathica."]),
 ("May-2016", ["Causes of exfoliative dermatitis; systemic manifestations and management.",
  "Cutaneous manifestations of internal malignancy.",
  "LASERS in dermatology.",
  "Classify cutaneous amyloidosis; lichen amyloidosis in detail; special stains.",
  "Short notes: Pseudoscleroderma; Thalidomide in dermatology; Angiokeratomas / angiokeratoma corporis diffusum."]),
 ("April-2017", ["Differential diagnosis of tender subcutaneous nodules in legs (30yo female); Erythema nodosum in detail.",
  "Dermatomyositis: classification, pathogenesis, clinical presentation, management.",
  "Role of Biologicals in Psoriasis (mechanism diagram, enumeration).",
  "Classify Dermatoses of Pregnancy; Herpes gestationis; management of pemphigoid gestationis in pregnancy.",
  "Short notes: Management of Hirsutism (20yo female); Figurate Erythema; Dermatological conditions with hoarseness of voice."]),
 ("April-2018", ["Etiopathogenesis, clinical features, investigations & treatment of Atopic Dermatitis.",
  "Cutaneous manifestations of collagen vascular diseases.",
  "Cyclosporine: mechanism, indications, contraindications, monitoring.",
  "Histiocytosis X.",
  "Short notes: Pseudoxanthoma Elasticum; Patch test; Management of Mycetoma."]),
 ("April-2019", ["Etiology, clinical features, diagnosis and management of Sarcoidosis.",
  "Approach to management of 34-year-old lady with Hirsutism.",
  "Classify Vasculitis. Management of 9-year-old girl with palpable purpura on lower extremities.",
  "Immunopathogenesis and clinical features of subepidermal blistering disorders.",
  "Short notes: Disorders of hair shaft; Rituximab in Dermatology; Laser resurfacing."]),
 ("June-2020", ["Approach to diagnosis/management in 7-year-old boy with fever and rash.",
  "Classify pustular psoriasis; provocative factors, clinical features, complications, management of generalized pustular psoriasis.",
  "Severe acne variants.",
  "Classify cutaneous tuberculosis; clinical features and management.",
  "Short notes: Melasma; Mycophenolate mofetil; Basal cell carcinoma."]),
 ("June-2021", ["Etiopathogenesis of Psoriasis Vulgaris; role of Biologics in management.",
  "Dermatomyositis: etiopathogenesis, classification/clinical features, investigations, management.",
  "Causes of Exfoliative Dermatitis; clinical features and management.",
  "Cutaneous Amyloidosis: classification, clinical manifestations, special stains.",
  "Short notes: Autoimmune Urticaria; Cutis Laxa; Thalidomide use in Dermatology."]),
 ("November-2022", ["Etiopathogenesis, clinical features and management of Epidermolysis bullosa acquisita.",
  "Commonest physiological skin changes in the newborn.",
  "Classification of porphyrias; clinical features & treatment of porphyria cutanea tarda.",
  "Etiology, clinical features and treatment of Sweet's syndrome.",
  "Short notes: Variants of acne; Hand, Foot and Mouth Disease; Wound dressing."]),
 ("July-2023", ["Classify deep fungal infections. Clinical features, diagnosis, management of Mycetoma.",
  "Etiopathogenesis, clinical features, investigations & treatment of Atopic Dermatitis.",
  "15yo male with purpuric lesions over legs - approach to diagnosis and management.",
  "Graft Vs Host disease.",
  "Short notes: Lipoid Proteinosis; Basal Cell Carcinoma; Newer Chemical Peels."]),
 ("January-2025", ["65yo female with fluid-filled lesions over trunk/limbs x3 months - diagnostic approach, investigations, management.",
  "35yo patient with soft-tissue swelling, nodules, sinuses on left foot - differential diagnosis and management.",
  "Hair cycle (diagram); anagen vs telogen effluvium; hair shaft disorders; dermoscopy of alopecia areata.",
  "Figurate erythemas.",
  "Short notes: Kawasaki Disease; Painful skin tumours; Pre-natal diagnosis of skin diseases."]),
 ("November-2025", ["Classify Psychocutaneous diseases. Matchbox Sign. Diogenes Syndrome. Delusional parasitosis (DD & treatment).",
  "Approach to a 30-year-old female with diffuse hair loss.",
  "Classify Palmo-Plantar Keratodermas; types with Transgrediens in detail.",
  "Psoriatic Arthropathy and its management.",
  "Short notes: Acute Skin failure; Cutaneous reactions to cold temperature; Zinc/essential fatty acid deficiency manifestations."]),
],
"PAPER III - Histopathology, Cosmetology, Leprosy and STD": [
 ("July-2015", ["Leprosy: structure of leprosy bacillus; animal models; persisters; rehabilitation.",
  "Syphilis: natural history untreated; serological tests; congenital syphilis; tabes dorsalis.",
  "Pathogenesis and management of plantar ulcers in leprosy.",
  "Specific cutaneous markers of HIV/AIDS.",
  "Short notes: Non Gonococcal urethritis; Methemoglobinemia; Fourth Generation Syphilis."]),
 ("May-2016", ["Etiopathogenesis and management of trophic ulcer in leprosy.",
  "Approach to diagnosis/management of vaginal discharge in a 25-year-old female.",
  "Immunopathogenesis of HIV infection.",
  "Newer drugs in Leprosy management.",
  "Short notes: STD Vaccines; Micro-needling radiofrequency in facial rejuvenation; Pseudoepitheliomatous hyperplasia."]),
 ("April-2017", ["Extended Syndromic Management of Genital Ulcer disease.",
  "Define Relapse; etiology, clinical features, investigations & management of relapse in Leprosy.",
  "Approach towards male patient with urethral discharge.",
  "Antiretroviral drugs.",
  "Short notes: Botox in dermatology; Histopathology of multibacillary Hansen's disease (BB/BL/LL); Fitz Hugh-Curtis Syndrome."]),
 ("April-2018", ["Leprosy: classification; serodiagnosis; radiological changes; role of thalidomide.",
  "Ultrastructure of HIV virus; HAART therapy; post exposure prophylaxis for HIV.",
  "Serological tests in syphilis; non-venereal treponematoses.",
  "Syndromic management for STI; National AIDS Control Program status.",
  "Short notes: Lymphatic drainage of male & female genitalia; Management of recurrent ENL; Bacterial vaginosis."]),
 ("April-2019", ["Classification, clinical features and management of deformities in Leprosy.",
  "Structure of causative organism of syphilis; etiopathogenesis, clinical features, serodiagnosis, management of secondary syphilis; congenital syphilis note.",
  "18-year-old male with urethral discharge - approach to diagnosis and management.",
  "Eye complications in Leprosy.",
  "Short notes: Post exposure prophylaxis in HIV infection; Newer facial peels; Interface dermatitis."]),
 ("June-2020", ["Pathogenesis, clinical features, investigations & management of 'reactions' in leprosy.",
  "Congenital syphilis: early, late, stigmata.",
  "Newer Antileprosy drugs.",
  "Reiter's Syndrome.",
  "Short notes: Chemical peeling in dermatology; Tuberculoid granuloma & differential diagnosis; Dermatological manifestations in HIV infection."]),
 ("June-2021", ["Leprosy: immunogenetics; lab/serological/molecular diagnosis; systemic involvement; NLEP.",
  "Herpes genitalis: investigations to confirm diagnosis; principles of management.",
  "Clinical types of genital warts; role of HPV vaccine.",
  "HIV: immunopathogenesis; antiretroviral therapy.",
  "Short notes: Animal models in Leprosy; Resistance in Leprosy; Non Gonococcal urethritis."]),
 ("November-2022", ["Differential diagnosis of infiltrated skin lesion in a leprosy patient.",
  "Syndromic approach to a patient with genital ulcer.",
  "Chancroid: clinical features, variants, complications, treatment.",
  "Histopathology of BB, BL and LL leprosy.",
  "Short notes: IRIS; Bacterial Vaginosis; Dapsone."]),
 ("July-2023", ["Rehabilitation of Leprosy; WHO disability grading.",
  "Syndromic approach for various STIs.",
  "Immunology of Leprosy; serodiagnosis of Leprosy.",
  "Congenital Syphilis: classification, clinical features, management.",
  "Short notes: Dapsone Hypersensitivity syndrome & Methemoglobinemia; Lymphatic drainage of female genitalia & female condom; LGV (etiology, manifestations, management)."]),
 ("January-2025", ["Type II Lepra reaction - what it is and how managed.",
  "25yo man with fever, urethral discharge, pain in urethra 4 days post sexual contact - management and complications.",
  "Care of hands and feet in Lepromatous Leprosy.",
  "Serological tests in syphilis; non-venereal treponematosis.",
  "Short notes: Leprosy Vaccines; Post exposure prophylaxis of HIV; Histopathology of Histoid Leprosy."]),
 ("November-2025", ["Complications of venereal diseases in a female.",
  "Immunology of Leprosy.",
  "Mucocutaneous complications of HIV/AIDS.",
  "Ocular manifestations of Leprosy.",
  "Short notes: Slit Skin Smear in Leprosy; Histopathology of Psoriasis; Donovanosis."]),
],
"PAPER IV - Recent Advances in Dermatology": [
 ("July-2015", ["Probiotics in Dermatology.",
  "Newer options in management of Acne Vulgaris.",
  "Surgical options for Vitiligo Therapy.",
  "Sensitive skin syndrome.",
  "Short notes: Nail Psoriasis; Janus-Kinase Inhibitors; Ultrasound in Dermatology."]),
 ("May-2016", ["Biologicals in Dermatology.",
  "Chronic Hand Dermatitis.",
  "Treatment of Acne Scars.",
  "Role of Diet in Acne.",
  "Short notes: Nail Psoriasis; Janus-Kinase Inhibitors; Ultrasound in Dermatology."]),
 ("May-2017", ["Mucocutaneous manifestations of HIV infection; lab diagnosis and ART.",
  "Pruritus: neuroanatomy, neuro-receptors, neuro-mediators of itch; topical/systemic treatment.",
  "Recent concepts in chemotherapy for Hansen's disease.",
  "Role of newer drugs in Hansen's disease.",
  "Short notes: Sweet's Syndrome; Anesthetic techniques in Dermatology; Recent advances in management of childhood psoriasis."]),
 ("April-2018", ["Composition of sebum; newer treatment modalities for Acne and Acne Scars.",
  "Calcineurin inhibitors: mode of action, dosing, uses.",
  "Total Steroid Dependent Face (TSDF): manifestations and management.",
  "Lights in dermatology.",
  "Short notes: DRESS Syndrome; Hidradenitis Suppurativa; PRP Therapy in dermatology."]),
 ("April-2019", ["Pathogenesis of vitiligo; non-cultured epidermal suspension in vitiligo.",
  "Basic principles of Lasers; lasers for various skin conditions; lasers for hair reduction.",
  "Keloid: treatment modalities.",
  "Hair transplantation.",
  "Short notes: Vaccines used in dermatology; Apremilast; Facial rejuvenation."]),
 ("June-2020", ["Etiopathogenesis, investigations & recent advances in management of Pemphigus.",
  "Classify leg ulcers; etiopathogenesis; recent advances in management.",
  "Light based devices in Dermatology therapy.",
  "Intralesional therapy in Dermatology.",
  "Short notes: Biological therapy in Dermatology; Sunscreens; USG in Dermatology."]),
 ("June-2021", ["Biologic drugs: classification; difference between biologics and biosimilars.",
  "Types of vitiligo surgeries; light and laser based therapies in vitiligo.",
  "Topical drug delivery systems; procedural dermatology as drug delivery.",
  "Indications, side effects, limitations of botulinum toxin in dermatology.",
  "Short notes: Classify chemical peels & Baker Gordon peel; Gene therapy in dermatology; Autologous serum and platelet based therapies."]),
 ("November-2022 (Supplementary)", ["Types of Acne scars; treatment modalities.",
  "Atopic dermatitis: recent advances in pathogenesis and management.",
  "Light based therapy in dermatology.",
  "Recent advances in treatment of psoriasis vulgaris.",
  "Short notes: Methods of Cryosurgery; Cutaneous manifestations of Covid-19; Teledermatology."]),
 ("July-2023", ["Classify Alopecia areata; pathogenesis; newer management modalities.",
  "Biological therapy in Dermatology; role in Bullous disorders.",
  "Laser therapy in Dermatology.",
  "Classify Alpha Hydroxy Acid peels; role in skin disorders.",
  "Short notes: Tranexamic acid in Dermatology; Janus kinase inhibitors; Retinoids in Dermatology."]),
 ("January-2025", ["Define and classify Urticaria; pathogenesis in detail.",
  "Androgenetic Alopecia: aetiology, grading, recent advances in management.",
  "Pruritus: classification, itch-pathway, topical & systemic treatment.",
  "Use of Dermatoscope in Trichology.",
  "Short notes: Artificial Intelligence in Dermatology; Regenerative medicine in Dermatology; Sunscreens in Dermatology."]),
 ("November-2025", ["Melasma: etiopathogenesis; recent advances in management.",
  "Light and Laser based therapy: dermatological and cosmetological indications.",
  "Etiopathogenesis and recent trends in management of Vitiligo.",
  "Use of different vaccines in dermatology.",
  "Short notes: Classify cutaneous amyloidosis; Biosimilars in dermatology; Stem cell therapy."]),
],
}

for paper_title, sessions in papers.items():
    doc.add_heading(paper_title, level=1)
    for session, qs in sessions:
        h = doc.add_heading(session, level=2)
        for i, q in enumerate(qs, start=1):
            label = f"Q{i}." if i <= 4 else "Short Notes:"
            para = doc.add_paragraph()
            run = para.add_run(f"{label} ")
            run.bold = True
            para.add_run(q)
    doc.add_page_break()

doc.save("/tmp/workspace/derm_exam_bank/MD_Dermatology_Question_Bank_2015-2025.docx")
print("Base document saved.")

Successfully replaced 1 instance(s) of the string in '/tmp/workspace/derm_exam_bank/build_doc.py'