Here is a simple, plain-language explanation of everything in that image:
Tests for Ovarian Reserve - Simply Explained
Ovarian reserve just means: how many eggs does a woman still have left? As women age, the number of eggs in their ovaries goes down. These tests help doctors figure out that number.
The Tests
1. FSH (Day 3)
- FSH = Follicle Stimulating Hormone - a signal from the brain telling the ovaries to grow eggs
- Normally, a healthy ovary responds easily, so the brain doesn't need to shout loudly
- If the ovaries are running low on eggs, the brain has to send a stronger signal = higher FSH
- High FSH = fewer eggs / ovaries struggling
2. E2 (Estrogen)
- Estrogen is made by the ovaries
- If the ovaries are failing, they produce less estrogen
- Low estrogen = ovarian failure
3. Anti-Mullerian Hormone (AMH)
- Made directly by the small follicles (egg sacs) in the ovary
- More follicles = more AMH
- Fewer follicles = less AMH
- Low AMH = fewer eggs remaining
- AMH is considered the BEST test for ovarian reserve because it stays fairly stable throughout the month (doesn't vary much with the cycle) - so you can test it on any day
4. Antral Follicle Count (AFC)
- Done via ultrasound - the doctor literally counts the tiny follicles visible in the ovaries
- Fewer follicles seen = lower ovarian reserve
Important Extra Points
Inhibin B - NOT a test for ovarian reserve. Instead, it's used as a marker for a specific ovarian tumor called a granulosa cell tumor. Don't confuse it with the others.
STRAW Staging - This is a system that maps out the stages of a woman's reproductive life, like chapters in a book:
- Early reproductive age
- Reproductive age (peak fertility)
- Late reproductive age (fertility declining)
- Early menopausal transition (cycles becoming irregular)
- Late menopausal transition (very irregular)
- Menopause (periods have stopped)
It helps doctors tell a woman exactly where she is in her reproductive timeline.
Quick Summary Table
| Test | What happens in ovarian failure | Best for? |
|---|
| FSH | Goes UP | Common screening |
| Estrogen (E2) | Goes DOWN | Supporting test |
| AMH | Goes DOWN | Best overall test |
| Antral Follicle Count | Goes DOWN | Ultrasound-based count |
The key idea: when the ovaries have fewer eggs, AMH, E2, and AFC all drop, while FSH rises (the brain tries harder to stimulate failing ovaries).