ls /home/daytona/workspace/ && mkdir -p /home/daytona/workspace/blood-physiology…

~/blood-physiology-ppt/create_pptx.js

const pptxgen = require("pptxgenjs");

const pres = new pptxgen();
pres.layout = "LAYOUT_16x9";
pres.title = "Blood Physiology";
pres.author = "Orris Medical";

// ─── COLOR PALETTE ───────────────────────────────────────────
const RED      = "C0392B";  // deep blood red (dominant)
const DARKRED  = "7B241C";  // darker red
const DARKBG   = "1A0A0A";  // near-black with red tint
const CARDBG   = "2C1010";  // dark card
const CARDBG2  = "3D1515";  // slightly lighter card
const WHITE    = "FFFFFF";
const OFFWHITE = "F5E6E6";  // warm off-white
const GRAY     = "D0B0B0";  // warm gray
const ACCENT   = "E74C3C";  // bright red accent
const LTRED    = "F1948A";  // light red for subtext
const GOLD     = "F39C12";  // gold for highlights

// ─── HELPERS ─────────────────────────────────────────────────
function addSlideHeader(slide, title, subtitle) {
  // Top accent bar
  slide.addShape(pres.shapes.RECTANGLE, {
    x: 0, y: 0, w: 10, h: 0.08, fill: { color: RED }, line: { color: RED }
  });
  // Left side accent
  slide.addShape(pres.shapes.RECTANGLE, {
    x: 0, y: 0.08, w: 0.07, h: 5.545, fill: { color: DARKRED }, line: { color: DARKRED }
  });
  slide.addText(title, {
    x: 0.3, y: 0.15, w: 9.4, h: 0.6,
    fontSize: 22, bold: true, color: WHITE, fontFace: "Calibri",
    margin: 0
  });
  if (subtitle) {
    slide.addText(subtitle, {
      x: 0.3, y: 0.72, w: 9.4, h: 0.3,
      fontSize: 11, color: LTRED, fontFace: "Calibri", margin: 0
    });
  }
  // bottom bar
  slide.addShape(pres.shapes.RECTANGLE, {
    x: 0, y: 5.55, w: 10, h: 0.075, fill: { color: DARKRED }, line: { color: DARKRED }
  });
}

function card(slide, x, y, w, h, color) {
  slide.addShape(pres.shapes.RECTANGLE, {
    x, y, w, h,
    fill: { color: color || CARDBG },
    line: { color: RED, pt: 1.2 },
    shadow: { type: "outer", color: "000000", blur: 8, offset: 3, angle: 135, opacity: 0.35 }
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 1 — TITLE
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKBG };

  // Large decorative circle
  s.addShape(pres.shapes.OVAL, {
    x: 6.2, y: -1.2, w: 5.5, h: 5.5,
    fill: { color: RED, transparency: 82 }, line: { color: RED, pt: 1.5 }
  });
  s.addShape(pres.shapes.OVAL, {
    x: 6.8, y: -0.6, w: 4.3, h: 4.3,
    fill: { color: RED, transparency: 88 }, line: { color: ACCENT, pt: 0.8 }
  });

  // Red top accent bar
  s.addShape(pres.shapes.RECTANGLE, {
    x: 0, y: 0, w: 5.5, h: 0.1, fill: { color: RED }, line: { color: RED }
  });

  // Main title
  s.addText("BLOOD", {
    x: 0.5, y: 0.8, w: 6, h: 1.3,
    fontSize: 72, bold: true, color: RED, fontFace: "Calibri",
    charSpacing: 8, margin: 0
  });
  s.addText("PHYSIOLOGY", {
    x: 0.5, y: 2.0, w: 6.5, h: 0.9,
    fontSize: 36, bold: false, color: WHITE, fontFace: "Calibri",
    charSpacing: 14, margin: 0
  });

  // Divider line
  s.addShape(pres.shapes.RECTANGLE, {
    x: 0.5, y: 3.0, w: 4.5, h: 0.05, fill: { color: ACCENT }, line: { color: ACCENT }
  });

  // Subtitle
  s.addText("Components • Functions • Disorders\nHuman Physiology", {
    x: 0.5, y: 3.18, w: 6, h: 0.8,
    fontSize: 13, color: GRAY, fontFace: "Calibri", margin: 0
  });

  // Bottom tag
  s.addText("Medical Physiology Series", {
    x: 0.5, y: 5.1, w: 4, h: 0.35,
    fontSize: 10, color: LTRED, fontFace: "Calibri", margin: 0
  });

  // Small RBC decorative dots
  for (let i = 0; i < 6; i++) {
    s.addShape(pres.shapes.OVAL, {
      x: 0.4 + i * 0.55, y: 4.7, w: 0.22, h: 0.22,
      fill: { color: RED, transparency: 60 }, line: { color: RED, pt: 0.5 }
    });
  }
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 2 — OVERVIEW / TABLE OF CONTENTS
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKBG };
  addSlideHeader(s, "Overview", "Topics covered in this presentation");

  const topics = [
    ["01", "Composition of Blood",      "Plasma, cells, volume"],
    ["02", "Red Blood Cells (RBCs)",     "Structure, function, lifespan"],
    ["03", "Haemoglobin",               "Structure, oxygen transport"],
    ["04", "White Blood Cells (WBCs)",   "Types and immune roles"],
    ["05", "Platelets & Haemostasis",   "Clotting cascade"],
    ["06", "Blood Groups",              "ABO and Rh systems"],
  ];

  topics.forEach(([num, title, sub], i) => {
    const col = i < 3 ? 0 : 1;
    const row = i % 3;
    const x = 0.4 + col * 4.85;
    const y = 1.1 + row * 1.42;

    card(s, x, y, 4.55, 1.22, CARDBG);
    s.addText(num, {
      x: x + 0.12, y: y + 0.1, w: 0.6, h: 0.55,
      fontSize: 22, bold: true, color: RED, fontFace: "Calibri", margin: 0
    });
    s.addShape(pres.shapes.RECTANGLE, {
      x: x + 0.72, y: y + 0.15, w: 0.04, h: 0.45,
      fill: { color: ACCENT }, line: { color: ACCENT }
    });
    s.addText(title, {
      x: x + 0.86, y: y + 0.1, w: 3.5, h: 0.45,
      fontSize: 13, bold: true, color: WHITE, fontFace: "Calibri", margin: 0
    });
    s.addText(sub, {
      x: x + 0.86, y: y + 0.62, w: 3.5, h: 0.35,
      fontSize: 9.5, color: GRAY, fontFace: "Calibri", margin: 0
    });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 3 — COMPOSITION OF BLOOD
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKBG };
  addSlideHeader(s, "Composition of Blood", "Blood is a specialized connective tissue");

  // Left text column
  card(s, 0.25, 1.05, 5.5, 4.35, CARDBG);

  s.addText("What is Blood?", {
    x: 0.45, y: 1.15, w: 5.1, h: 0.4,
    fontSize: 14, bold: true, color: ACCENT, fontFace: "Calibri", margin: 0
  });
  s.addText([
    { text: "Blood is a fluid connective tissue that circulates through the cardiovascular system. In a 70 kg man:", options: { breakLine: true } },
  ], {
    x: 0.45, y: 1.58, w: 5.1, h: 0.55,
    fontSize: 10.5, color: OFFWHITE, fontFace: "Calibri"
  });

  const stats = [
    ["Total Volume", "~5 Litres (7% body weight)"],
    ["Plasma", "~55–60% of blood"],
    ["Formed Elements", "~40–45% of blood"],
    ["pH", "7.35 – 7.45 (slightly alkaline)"],
    ["Specific Gravity", "1.050 – 1.060"],
    ["Viscosity", "3–4× that of water"],
    ["Temperature", "38°C (slightly > body temp)"],
  ];

  stats.forEach(([k, v], i) => {
    const y = 2.18 + i * 0.46;
    s.addShape(pres.shapes.RECTANGLE, {
      x: 0.45, y, w: 0.06, h: 0.28,
      fill: { color: RED }, line: { color: RED }
    });
    s.addText(k + ":", {
      x: 0.62, y, w: 1.8, h: 0.3,
      fontSize: 10, bold: true, color: LTRED, fontFace: "Calibri", margin: 0
    });
    s.addText(v, {
      x: 2.4, y, w: 3.2, h: 0.3,
      fontSize: 10, color: WHITE, fontFace: "Calibri", margin: 0
    });
  });

  // Right — pie-like breakdown chart
  card(s, 5.95, 1.05, 3.8, 4.35, CARDBG2);
  s.addText("BLOOD COMPONENTS", {
    x: 6.05, y: 1.15, w: 3.6, h: 0.35,
    fontSize: 10, bold: true, color: ACCENT, fontFace: "Calibri", align: "center", margin: 0
  });

  // Vertical stacked bar visual
  const barX = 7.0, barY = 1.6, barW = 1.8;
  // Plasma bar
  s.addShape(pres.shapes.RECTANGLE, {
    x: barX, y: barY, w: barW, h: 2.4,
    fill: { color: "5D6D7E" }, line: { color: "7F8C8D", pt: 0.5 }
  });
  s.addText("PLASMA\n55%", {
    x: barX, y: barY + 0.9, w: barW, h: 0.7,
    fontSize: 11, bold: true, color: WHITE, fontFace: "Calibri", align: "center", margin: 0
  });
  // RBC bar
  s.addShape(pres.shapes.RECTANGLE, {
    x: barX, y: barY + 2.4, w: barW, h: 1.6,
    fill: { color: RED }, line: { color: ACCENT, pt: 0.5 }
  });
  s.addText("RBCs\n40%", {
    x: barX, y: barY + 2.55, w: barW, h: 0.65,
    fontSize: 11, bold: true, color: WHITE, fontFace: "Calibri", align: "center", margin: 0
  });
  // WBC/Platelet buffy coat
  s.addShape(pres.shapes.RECTANGLE, {
    x: barX, y: barY + 4.0, w: barW, h: 0.25,
    fill: { color: GOLD }, line: { color: GOLD, pt: 0.5 }
  });
  s.addText("WBCs + Platelets ~1%", {
    x: barX - 0.3, y: barY + 4.2, w: barW + 0.7, h: 0.25,
    fontSize: 8, color: GOLD, fontFace: "Calibri", align: "center", margin: 0
  });

  // Legend
  const legend = [
    [GRAY, "Plasma — water, proteins, electrolytes"],
    [RED, "Red Blood Cells (Erythrocytes)"],
    [GOLD, "WBCs (Leukocytes) + Platelets"],
  ];
  legend.forEach(([col, txt], i) => {
    s.addShape(pres.shapes.RECTANGLE, {
      x: 6.1, y: 3.65 + i * 0.38, w: 0.22, h: 0.18,
      fill: { color: col }, line: { color: col }
    });
    s.addText(txt, {
      x: 6.4, y: 3.62 + i * 0.38, w: 3.3, h: 0.25,
      fontSize: 8.5, color: GRAY, fontFace: "Calibri", margin: 0
    });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 4 — PLASMA
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKBG };
  addSlideHeader(s, "Blood Plasma", "The liquid matrix of blood (~55% of total blood volume)");

  const cols = [
    {
      title: "Water (91–92%)",
      color: "2E86C1",
      points: ["Solvent for all dissolved substances", "Medium for transport of gases, nutrients, waste", "Regulates body temperature"]
    },
    {
      title: "Plasma Proteins (7–8%)",
      color: RED,
      points: ["Albumin — oncotic pressure, carrier", "Globulins — immunity (IgG, IgA, IgM)", "Fibrinogen — blood coagulation", "Made mostly in liver (except Ig)"]
    },
    {
      title: "Other Solutes (1–2%)",
      color: GOLD,
      points: ["Electrolytes: Na⁺, K⁺, Ca²⁺, Cl⁻, HCO₃⁻", "Glucose, amino acids, fatty acids", "Waste: urea, creatinine, bilirubin", "Hormones, vitamins, gases (O₂, CO₂)"]
    }
  ];

  cols.forEach((col, i) => {
    const x = 0.22 + i * 3.25;
    card(s, x, 1.05, 3.1, 4.35, CARDBG);
    // Header bar
    s.addShape(pres.shapes.RECTANGLE, {
      x, y: 1.05, w: 3.1, h: 0.38, fill: { color: col.color }, line: { color: col.color }
    });
    s.addText(col.title, {
      x: x + 0.1, y: 1.07, w: 2.9, h: 0.35,
      fontSize: 10.5, bold: true, color: WHITE, fontFace: "Calibri", margin: 0
    });
    col.points.forEach((pt, j) => {
      s.addShape(pres.shapes.OVAL, {
        x: x + 0.18, y: 1.65 + j * 0.74, w: 0.12, h: 0.12,
        fill: { color: col.color }, line: { color: col.color }
      });
      s.addText(pt, {
        x: x + 0.38, y: 1.6 + j * 0.74, w: 2.62, h: 0.62,
        fontSize: 9.5, color: OFFWHITE, fontFace: "Calibri", margin: 0
      });
    });
  });

  // Bottom key fact
  s.addShape(pres.shapes.RECTANGLE, {
    x: 0.22, y: 5.22, w: 9.56, h: 0.0, fill: { color: DARKRED }, line: { color: DARKRED, pt: 0 }
  });
  s.addText("📌  Plasma without fibrinogen = Serum  |  Normal plasma protein = 6–8 g/dL  |  Albumin = 3.5–5 g/dL", {
    x: 0.3, y: 5.1, w: 9.4, h: 0.3,
    fontSize: 9, color: GOLD, fontFace: "Calibri", italic: true, margin: 0
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 5 — RED BLOOD CELLS
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKBG };
  addSlideHeader(s, "Red Blood Cells (Erythrocytes)", "Most abundant formed element in blood");

  // Left big card
  card(s, 0.25, 1.05, 5.5, 4.35, CARDBG);

  const rbcFacts = [
    ["Shape", "Biconcave disc (no nucleus in mature form)"],
    ["Diameter", "6–8 μm"],
    ["Thickness", "2 μm at rim, 1 μm at centre"],
    ["Count (male)", "4.5–6.5 million/μL"],
    ["Count (female)", "3.8–5.8 million/μL"],
    ["Lifespan", "~120 days"],
    ["Production", "Erythropoiesis in red bone marrow"],
    ["Destruction", "Spleen & liver (reticuloendothelial system)"],
    ["Main protein", "Haemoglobin (~33% of RBC mass)"],
  ];

  s.addText("Key Facts", {
    x: 0.45, y: 1.15, w: 5.1, h: 0.38,
    fontSize: 13, bold: true, color: ACCENT, fontFace: "Calibri", margin: 0
  });

  rbcFacts.forEach(([k, v], i) => {
    const y = 1.6 + i * 0.42;
    const rowBg = i % 2 === 0 ? CARDBG : "3A1212";
    s.addShape(pres.shapes.RECTANGLE, {
      x: 0.3, y, w: 5.3, h: 0.38, fill: { color: rowBg }, line: { color: rowBg }
    });
    s.addText(k, {
      x: 0.4, y: y + 0.05, w: 1.7, h: 0.28,
      fontSize: 9.5, bold: true, color: LTRED, fontFace: "Calibri", margin: 0
    });
    s.addText(v, {
      x: 2.1, y: y + 0.05, w: 3.4, h: 0.28,
      fontSize: 9.5, color: WHITE, fontFace: "Calibri", margin: 0
    });
  });

  // Right column — functions & regulation
  card(s, 5.95, 1.05, 3.8, 2.0, CARDBG2);
  s.addText("FUNCTIONS", {
    x: 6.05, y: 1.12, w: 3.6, h: 0.32,
    fontSize: 11, bold: true, color: RED, fontFace: "Calibri", margin: 0
  });
  const funcs = [
    "O₂ transport: O₂ lungs → tissues",
    "CO₂ transport: tissues → lungs",
    "Acid-base buffering (HbH⁺)",
    "Nitric oxide transport",
  ];
  funcs.forEach((f, i) => {
    s.addShape(pres.shapes.OVAL, {
      x: 6.1, y: 1.52 + i * 0.36, w: 0.1, h: 0.1,
      fill: { color: ACCENT }, line: { color: ACCENT }
    });
    s.addText(f, {
      x: 6.28, y: 1.48 + i * 0.36, w: 3.3, h: 0.3,
      fontSize: 9.5, color: OFFWHITE, fontFace: "Calibri", margin: 0
    });
  });

  card(s, 5.95, 3.22, 3.8, 2.18, CARDBG2);
  s.addText("ERYTHROPOIESIS CONTROL", {
    x: 6.05, y: 3.3, w: 3.6, h: 0.32,
    fontSize: 11, bold: true, color: RED, fontFace: "Calibri", margin: 0
  });
  const erythro = [
    "↓ O₂ → kidney releases Erythropoietin (EPO)",
    "EPO → stimulates red bone marrow",
    "Reticulocytes released into blood",
    "Mature in 1–2 days → RBC",
    "Requires: Fe, B12, folate, B6",
  ];
  erythro.forEach((e, i) => {
    s.addShape(pres.shapes.RECTANGLE, {
      x: 6.1, y: 3.72 + i * 0.32, w: 0.08, h: 0.2,
      fill: { color: RED }, line: { color: RED }
    });
    s.addText(e, {
      x: 6.28, y: 3.7 + i * 0.32, w: 3.35, h: 0.28,
      fontSize: 9, color: OFFWHITE, fontFace: "Calibri", margin: 0
    });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 6 — HAEMOGLOBIN
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKBG };
  addSlideHeader(s, "Haemoglobin (Hb)", "The oxygen-carrying protein of red blood cells");

  // Structure card
  card(s, 0.25, 1.05, 4.6, 4.35, CARDBG);
  s.addText("Structure", {
    x: 0.45, y: 1.12, w: 4.2, h: 0.38,
    fontSize: 13, bold: true, color: ACCENT, fontFace: "Calibri", margin: 0
  });

  const structureInfo = [
    "Molecular weight: 68,000 daltons",
    "4 polypeptide chains (globin)",
    "Each chain carries 1 haem group",
    "Each haem: 1 Fe²⁺ ion",
    "1 Hb molecule binds 4 O₂ molecules",
    "Normal values: Male 14–18 g/dL",
    "                      Female 12–16 g/dL",
    "Total body Hb: ~750g in adult male",
  ];
  structureInfo.forEach((info, i) => {
    s.addShape(pres.shapes.OVAL, {
      x: 0.42, y: 1.6 + i * 0.41, w: 0.1, h: 0.1,
      fill: { color: RED }, line: { color: RED }
    });
    s.addText(info, {
      x: 0.62, y: 1.56 + i * 0.41, w: 4.1, h: 0.35,
      fontSize: 9.5, color: OFFWHITE, fontFace: "Calibri", margin: 0
    });
  });

  // Right — Types of Hb
  card(s, 5.05, 1.05, 4.7, 1.95, CARDBG2);
  s.addText("Types of Haemoglobin", {
    x: 5.2, y: 1.12, w: 4.4, h: 0.35,
    fontSize: 12, bold: true, color: RED, fontFace: "Calibri", margin: 0
  });
  const hbTypes = [
    ["HbA (adult)", "α₂β₂", "96–98% in adults"],
    ["HbA₂", "α₂δ₂", "~2% in adults"],
    ["HbF (fetal)", "α₂γ₂", "High O₂ affinity"],
    ["HbS (sickle)", "Abnormal β", "Causes sickle cell disease"],
  ];
  hbTypes.forEach(([name, chains, note], i) => {
    s.addText(name, {
      x: 5.15, y: 1.55 + i * 0.33, w: 1.5, h: 0.28,
      fontSize: 9, bold: true, color: LTRED, fontFace: "Calibri", margin: 0
    });
    s.addText(chains, {
      x: 6.65, y: 1.55 + i * 0.33, w: 0.8, h: 0.28,
      fontSize: 9, color: GOLD, fontFace: "Calibri", margin: 0
    });
    s.addText(note, {
      x: 7.45, y: 1.55 + i * 0.33, w: 2.2, h: 0.28,
      fontSize: 9, color: GRAY, fontFace: "Calibri", margin: 0
    });
  });

  // O2 dissociation curve description
  card(s, 5.05, 3.15, 4.7, 2.25, CARDBG2);
  s.addText("O₂ Dissociation Curve", {
    x: 5.2, y: 3.22, w: 4.4, h: 0.35,
    fontSize: 12, bold: true, color: RED, fontFace: "Calibri", margin: 0
  });
  s.addText("Sigmoidal (S-shaped) curve due to cooperative binding", {
    x: 5.2, y: 3.6, w: 4.4, h: 0.3,
    fontSize: 9.5, color: OFFWHITE, fontFace: "Calibri", margin: 0
  });
  const shiftFacts = [
    ["RIGHT SHIFT (↓ affinity)", "↑ CO₂, ↑ Temp, ↑ H⁺ (↓pH), ↑ 2,3-DPG"],
    ["LEFT SHIFT (↑ affinity)", "↓ CO₂, ↓ Temp, ↓ H⁺ (↑pH), HbF, CO"],
  ];
  shiftFacts.forEach(([label, detail], i) => {
    const bColor = i === 0 ? ACCENT : "2E86C1";
    s.addShape(pres.shapes.RECTANGLE, {
      x: 5.15, y: 4.0 + i * 0.65, w: 1.55, h: 0.28,
      fill: { color: bColor }, line: { color: bColor }
    });
    s.addText(label, {
      x: 5.18, y: 4.0 + i * 0.65, w: 1.5, h: 0.28,
      fontSize: 7.5, bold: true, color: WHITE, fontFace: "Calibri", align: "center", margin: 0
    });
    s.addText(detail, {
      x: 6.78, y: 4.0 + i * 0.65, w: 2.9, h: 0.28,
      fontSize: 8.5, color: OFFWHITE, fontFace: "Calibri", margin: 0
    });
  });
  s.addText("P₅₀ = PO₂ at which Hb is 50% saturated = 26–27 mmHg (normal)", {
    x: 5.15, y: 5.1, w: 4.6, h: 0.28,
    fontSize: 8.5, color: GOLD, fontFace: "Calibri", italic: true, margin: 0
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 7 — WHITE BLOOD CELLS
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKBG };
  addSlideHeader(s, "White Blood Cells (Leukocytes)", "Cellular soldiers of the immune system");

  s.addText("Normal WBC count: 4,000 – 11,000 /μL  |  Differential count identifies subtype proportions", {
    x: 0.3, y: 1.08, w: 9.4, h: 0.28,
    fontSize: 9.5, color: GOLD, fontFace: "Calibri", italic: true, margin: 0
  });

  const wbcTypes = [
    { name: "Neutrophils",   pct: "50–70%", color: "2874A6", role: "First responders — phagocytose bacteria", multi: "Multi-lobed nucleus (PMN)" },
    { name: "Lymphocytes",   pct: "20–40%", color: "1E8449", role: "B cells (antibodies) & T cells (cell-mediated immunity)", multi: "Large round nucleus" },
    { name: "Monocytes",     pct: "2–8%",   color: "6C3483", role: "Differentiate into macrophages — phagocytosis, APC", multi: "Kidney-shaped nucleus" },
    { name: "Eosinophils",   pct: "1–4%",   color: GOLD,     role: "Allergic reactions, parasite defense", multi: "Bilobed nucleus, red granules" },
    { name: "Basophils",     pct: "0–1%",   color: ACCENT,   role: "Release histamine & heparin — allergic reactions", multi: "S-shaped nucleus, blue granules" },
  ];

  wbcTypes.forEach((wbc, i) => {
    const x = 0.22;
    const y = 1.42 + i * 0.82;
    card(s, x, y, 9.56, 0.72, CARDBG);
    s.addShape(pres.shapes.RECTANGLE, {
      x, y, w: 0.12, h: 0.72, fill: { color: wbc.color }, line: { color: wbc.color }
    });
    s.addText(wbc.name, {
      x: x + 0.22, y: y + 0.08, w: 2.0, h: 0.3,
      fontSize: 12, bold: true, color: WHITE, fontFace: "Calibri", margin: 0
    });
    s.addShape(pres.shapes.RECTANGLE, {
      x: x + 0.22, y: y + 0.38, w: 1.5, h: 0.22,
      fill: { color: wbc.color }, line: { color: wbc.color }
    });
    s.addText(wbc.pct, {
      x: x + 0.24, y: y + 0.38, w: 1.48, h: 0.22,
      fontSize: 9, bold: true, color: WHITE, fontFace: "Calibri", align: "center", margin: 0
    });
    s.addText(wbc.role, {
      x: x + 2.4, y: y + 0.1, w: 4.7, h: 0.3,
      fontSize: 10, color: OFFWHITE, fontFace: "Calibri", margin: 0
    });
    s.addText(wbc.multi, {
      x: x + 2.4, y: y + 0.4, w: 4.7, h: 0.24,
      fontSize: 8.5, color: GRAY, fontFace: "Calibri", italic: true, margin: 0
    });
    s.addText("Leukocyte", {
      x: x + 7.4, y: y + 0.2, w: 2.1, h: 0.28,
      fontSize: 8.5, color: GRAY, fontFace: "Calibri", align: "right", margin: 0
    });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 8 — PLATELETS & HAEMOSTASIS
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKBG };
  addSlideHeader(s, "Platelets & Haemostasis", "The blood clotting system");

  // Platelets card
  card(s, 0.25, 1.05, 4.3, 2.2, CARDBG);
  s.addText("Platelets (Thrombocytes)", {
    x: 0.42, y: 1.12, w: 4.0, h: 0.38,
    fontSize: 12, bold: true, color: ACCENT, fontFace: "Calibri", margin: 0
  });
  const platFacts = [
    "Count: 150,000 – 400,000 /μL",
    "Size: 2–4 μm (smallest cells)",
    "Origin: Megakaryocytes in bone marrow",
    "Lifespan: 8–12 days",
    "No nucleus — contain granules",
    "Destroyed in spleen",
  ];
  platFacts.forEach((f, i) => {
    s.addShape(pres.shapes.OVAL, {
      x: 0.4, y: 1.6 + i * 0.26, w: 0.09, h: 0.09,
      fill: { color: RED }, line: { color: RED }
    });
    s.addText(f, {
      x: 0.58, y: 1.57 + i * 0.26, w: 3.8, h: 0.24,
      fontSize: 9.5, color: OFFWHITE, fontFace: "Calibri", margin: 0
    });
  });

  // Haemostasis steps
  card(s, 0.25, 3.35, 4.3, 2.05, CARDBG);
  s.addText("Steps of Haemostasis", {
    x: 0.42, y: 3.42, w: 4.0, h: 0.35,
    fontSize: 12, bold: true, color: ACCENT, fontFace: "Calibri", margin: 0
  });
  const hemoSteps = [
    ["1", "Vascular spasm — immediate vasoconstriction"],
    ["2", "Platelet plug formation (primary haemostasis)"],
    ["3", "Coagulation cascade (secondary haemostasis)"],
    ["4", "Fibrinolysis — clot dissolution (plasmin)"],
  ];
  hemoSteps.forEach(([n, txt], i) => {
    s.addShape(pres.shapes.OVAL, {
      x: 0.4, y: 3.88 + i * 0.36, w: 0.28, h: 0.28,
      fill: { color: RED }, line: { color: RED }
    });
    s.addText(n, {
      x: 0.4, y: 3.88 + i * 0.36, w: 0.28, h: 0.28,
      fontSize: 9, bold: true, color: WHITE, fontFace: "Calibri", align: "center", margin: 0
    });
    s.addText(txt, {
      x: 0.78, y: 3.88 + i * 0.36, w: 3.65, h: 0.28,
      fontSize: 9.5, color: OFFWHITE, fontFace: "Calibri", margin: 0
    });
  });

  // Coagulation cascade
  card(s, 4.75, 1.05, 5.0, 4.35, CARDBG2);
  s.addText("Coagulation Cascade", {
    x: 4.92, y: 1.12, w: 4.7, h: 0.38,
    fontSize: 13, bold: true, color: RED, fontFace: "Calibri", margin: 0
  });

  // Intrinsic pathway
  s.addText("INTRINSIC PATHWAY", {
    x: 4.92, y: 1.57, w: 2.1, h: 0.28,
    fontSize: 8.5, bold: true, color: "2E86C1", fontFace: "Calibri", margin: 0
  });
  const intrinsic = ["Factor XII (Hageman)", "↓", "XI → IX → VIII", "↓", "Factor X activated"];
  intrinsic.forEach((step, i) => {
    s.addText(step, {
      x: 4.92, y: 1.9 + i * 0.38, w: 2.2, h: 0.32,
      fontSize: 9, color: i === 4 ? GOLD : OFFWHITE, fontFace: "Calibri",
      bold: i === 4, align: "left", margin: 0
    });
  });

  // Extrinsic pathway
  s.addText("EXTRINSIC PATHWAY", {
    x: 7.22, y: 1.57, w: 2.4, h: 0.28,
    fontSize: 8.5, bold: true, color: ACCENT, fontFace: "Calibri", margin: 0
  });
  const extrinsic = ["Tissue Factor (III)", "↓", "Factor VII → VIIa", "↓", "Factor X activated"];
  extrinsic.forEach((step, i) => {
    s.addText(step, {
      x: 7.22, y: 1.9 + i * 0.38, w: 2.4, h: 0.32,
      fontSize: 9, color: i === 4 ? GOLD : OFFWHITE, fontFace: "Calibri",
      bold: i === 4, margin: 0
    });
  });

  // Convergence arrow
  s.addShape(pres.shapes.RECTANGLE, {
    x: 5.05, y: 3.9, w: 4.6, h: 0.04, fill: { color: GOLD }, line: { color: GOLD }
  });
  s.addText("COMMON PATHWAY", {
    x: 5.8, y: 3.98, w: 3.0, h: 0.28,
    fontSize: 9, bold: true, color: GOLD, fontFace: "Calibri", align: "center", margin: 0
  });
  const common = ["X + Va + Ca²⁺ → Prothrombinase", "Prothrombin → Thrombin", "Fibrinogen → Fibrin (clot)"];
  common.forEach((step, i) => {
    s.addText("→ " + step, {
      x: 4.92, y: 4.3 + i * 0.32, w: 4.7, h: 0.28,
      fontSize: 9, color: OFFWHITE, fontFace: "Calibri", margin: 0
    });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 9 — BLOOD GROUPS
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKBG };
  addSlideHeader(s, "Blood Groups", "ABO system and Rh system");

  // ABO table
  card(s, 0.25, 1.05, 5.55, 3.2, CARDBG);
  s.addText("ABO Blood Group System", {
    x: 0.42, y: 1.12, w: 5.2, h: 0.38,
    fontSize: 13, bold: true, color: ACCENT, fontFace: "Calibri", margin: 0
  });

  // Table
  const headers = ["Blood Group", "Antigen on RBC", "Antibody in Plasma", "Can Donate To", "Can Receive From"];
  const rows = [
    ["A",  "A",    "Anti-B",        "A, AB",    "A, O"],
    ["B",  "B",    "Anti-A",        "B, AB",    "B, O"],
    ["AB", "A & B","None",          "AB only",  "All groups"],
    ["O",  "None", "Anti-A, Anti-B","All groups","O only"],
  ];

  headers.forEach((h, i) => {
    s.addShape(pres.shapes.RECTANGLE, {
      x: 0.3 + i * 1.07, y: 1.58, w: 1.06, h: 0.3,
      fill: { color: DARKRED }, line: { color: RED, pt: 0.5 }
    });
    s.addText(h, {
      x: 0.31 + i * 1.07, y: 1.58, w: 1.04, h: 0.3,
      fontSize: 7.5, bold: true, color: WHITE, fontFace: "Calibri", align: "center", margin: 0
    });
  });

  rows.forEach((row, ri) => {
    const rowColor = ri % 2 === 0 ? CARDBG : "3A1212";
    row.forEach((cell, ci) => {
      s.addShape(pres.shapes.RECTANGLE, {
        x: 0.3 + ci * 1.07, y: 1.9 + ri * 0.36, w: 1.06, h: 0.34,
        fill: { color: rowColor }, line: { color: "4A1010", pt: 0.5 }
      });
      const isGroup = ci === 0;
      s.addText(cell, {
        x: 0.31 + ci * 1.07, y: 1.91 + ri * 0.36, w: 1.04, h: 0.3,
        fontSize: 8.5, bold: isGroup, color: isGroup ? GOLD : OFFWHITE,
        fontFace: "Calibri", align: "center", margin: 0
      });
    });
  });

  // O universal donor, AB universal recipient
  s.addText("O = Universal Donor  |  AB = Universal Recipient", {
    x: 0.42, y: 4.0, w: 5.3, h: 0.25,
    fontSize: 9, bold: true, color: GOLD, fontFace: "Calibri", margin: 0
  });

  // Rh System
  card(s, 5.95, 1.05, 3.8, 4.35, CARDBG2);
  s.addText("Rh Blood Group System", {
    x: 6.05, y: 1.12, w: 3.6, h: 0.38,
    fontSize: 12, bold: true, color: RED, fontFace: "Calibri", margin: 0
  });

  const rhFacts = [
    "Most important after ABO system",
    "Rh+ (D antigen present): ~85% people",
    "Rh− (D antigen absent): ~15% people",
    "No naturally occurring antibodies",
    "Anti-D forms only after exposure",
    "",
    "Erythroblastosis Fetalis:",
    "• Rh− mother + Rh+ fetus",
    "• 1st pregnancy: sensitization",
    "• 2nd pregnancy: anti-D crosses",
    "  placenta → haemolysis in fetus",
    "• Prevention: Anti-D (Rhogam) injection",
    "  within 72 hrs of delivery/abortion",
  ];

  rhFacts.forEach((f, i) => {
    if (f === "") return;
    const isBold = f.endsWith(":") || f.startsWith("Rh");
    s.addText(f, {
      x: 6.08, y: 1.6 + i * 0.26, w: 3.55, h: 0.26,
      fontSize: 8.8, bold: isBold, color: isBold ? LTRED : OFFWHITE,
      fontFace: "Calibri", margin: 0
    });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 10 — ANAEMIA
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKBG };
  addSlideHeader(s, "Anaemia", "Reduction in haemoglobin, RBC count, or haematocrit");

  s.addText("Definition: Hb < 13 g/dL (male)  or  < 12 g/dL (female)", {
    x: 0.3, y: 1.07, w: 9.4, h: 0.28,
    fontSize: 10, bold: true, color: GOLD, fontFace: "Calibri", margin: 0
  });

  const anaemiaTypes = [
    { title: "Iron Deficiency Anaemia", color: ACCENT, facts: ["Most common worldwide", "Microcytic hypochromic RBCs", "Causes: poor diet, blood loss, malabsorption", "Tx: oral iron supplements"] },
    { title: "Megaloblastic Anaemia",   color: "2E86C1", facts: ["Deficiency of B12 or folate", "Macrocytic RBCs (large, immature)", "Pernicious anaemia = B12 + intrinsic factor lack", "Tx: B12/folate replacement"] },
    { title: "Haemolytic Anaemia",      color: GOLD, facts: ["Premature RBC destruction", "Causes: sickle cell, thalassaemia, G6PD deficiency", "Features: jaundice, splenomegaly", "Tx: treat cause, transfusion"] },
    { title: "Aplastic Anaemia",        color: "6C3483", facts: ["Bone marrow failure — pancytopenia", "Causes: drugs, radiation, autoimmune, viruses", "All cell lines reduced (RBC, WBC, platelets)", "Tx: BMT, immunosuppression"] },
  ];

  anaemiaTypes.forEach((type, i) => {
    const col = i < 2 ? 0 : 1;
    const row = i % 2;
    const x = 0.22 + col * 4.9;
    const y = 1.42 + row * 2.15;

    card(s, x, y, 4.65, 2.0, CARDBG);
    s.addShape(pres.shapes.RECTANGLE, {
      x, y, w: 4.65, h: 0.35, fill: { color: type.color }, line: { color: type.color }
    });
    s.addText(type.title, {
      x: x + 0.1, y: y + 0.03, w: 4.45, h: 0.3,
      fontSize: 10.5, bold: true, color: WHITE, fontFace: "Calibri", margin: 0
    });
    type.facts.forEach((fact, j) => {
      s.addShape(pres.shapes.OVAL, {
        x: x + 0.15, y: y + 0.5 + j * 0.36, w: 0.09, h: 0.09,
        fill: { color: type.color }, line: { color: type.color }
      });
      s.addText(fact, {
        x: x + 0.32, y: y + 0.45 + j * 0.36, w: 4.2, h: 0.32,
        fontSize: 9, color: OFFWHITE, fontFace: "Calibri", margin: 0
      });
    });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 11 — HEMATOCRIT & BLOOD INDICES
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKBG };
  addSlideHeader(s, "Haematocrit & Blood Indices", "Key measurements in clinical haematology");

  // Left column
  card(s, 0.25, 1.05, 4.5, 4.35, CARDBG);
  s.addText("Haematocrit (Packed Cell Volume)", {
    x: 0.42, y: 1.12, w: 4.2, h: 0.38,
    fontSize: 12, bold: true, color: ACCENT, fontFace: "Calibri", margin: 0
  });
  const hctFacts = [
    ["Normal (Male)", "40 – 52%"],
    ["Normal (Female)", "35 – 47%"],
    ["Newborn", "44 – 64%"],
    ["Anaemia", "< 30%"],
    ["Polycythaemia", "> 60%"],
    ["Method", "Centrifuge blood, measure RBC column"],
  ];
  hctFacts.forEach(([k, v], i) => {
    const y = 1.58 + i * 0.46;
    const rowBg = i % 2 === 0 ? CARDBG : "3A1212";
    s.addShape(pres.shapes.RECTANGLE, {
      x: 0.3, y, w: 4.35, h: 0.4, fill: { color: rowBg }, line: { color: rowBg }
    });
    s.addText(k, { x: 0.4, y: y + 0.07, w: 1.9, h: 0.28, fontSize: 9.5, bold: true, color: LTRED, fontFace: "Calibri", margin: 0 });
    s.addText(v, { x: 2.3, y: y + 0.07, w: 2.2, h: 0.28, fontSize: 9.5, color: WHITE, fontFace: "Calibri", margin: 0 });
  });

  // Right — blood indices
  card(s, 4.95, 1.05, 4.8, 4.35, CARDBG2);
  s.addText("Red Cell Indices", {
    x: 5.1, y: 1.12, w: 4.5, h: 0.38,
    fontSize: 12, bold: true, color: RED, fontFace: "Calibri", margin: 0
  });

  const indices = [
    { name: "MCV", full: "Mean Corpuscular Volume", norm: "80 – 100 fL", info: "Size of RBC. Low=microcytic, High=macrocytic" },
    { name: "MCH", full: "Mean Corpuscular Hb", norm: "27 – 33 pg", info: "Amount of Hb per RBC" },
    { name: "MCHC", full: "Mean Corpuscular Hb Concentration", norm: "32 – 36 g/dL", info: "Hb concentration in RBCs" },
    { name: "RDW", full: "Red Cell Distribution Width", norm: "11.5 – 14.5%", info: "Variation in RBC size (anisocytosis)" },
    { name: "Reticulocytes", full: "Immature RBCs", norm: "0.5 – 1.5%", info: "Indicator of bone marrow activity" },
  ];

  indices.forEach((idx, i) => {
    const y = 1.58 + i * 0.74;
    card(s, 5.05, y, 4.65, 0.66, "2C1010");
    s.addShape(pres.shapes.RECTANGLE, {
      x: 5.05, y, w: 0.08, h: 0.66, fill: { color: RED }, line: { color: RED }
    });
    s.addText(idx.name, { x: 5.22, y: y + 0.06, w: 1.0, h: 0.28, fontSize: 11, bold: true, color: GOLD, fontFace: "Calibri", margin: 0 });
    s.addText(idx.full, { x: 6.22, y: y + 0.06, w: 3.35, h: 0.28, fontSize: 9, color: LTRED, fontFace: "Calibri", margin: 0 });
    s.addText("Normal: " + idx.norm, { x: 5.22, y: y + 0.35, w: 1.7, h: 0.24, fontSize: 8.5, color: WHITE, fontFace: "Calibri", margin: 0 });
    s.addText(idx.info, { x: 6.95, y: y + 0.35, w: 2.65, h: 0.24, fontSize: 8, color: GRAY, fontFace: "Calibri", margin: 0 });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 12 — SUMMARY / CONCLUSION
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKBG };

  // Top bar
  s.addShape(pres.shapes.RECTANGLE, {
    x: 0, y: 0, w: 10, h: 0.08, fill: { color: RED }, line: { color: RED }
  });
  // Bottom bar
  s.addShape(pres.shapes.RECTANGLE, {
    x: 0, y: 5.55, w: 10, h: 0.075, fill: { color: DARKRED }, line: { color: DARKRED }
  });

  s.addText("KEY TAKEAWAYS", {
    x: 0.4, y: 0.2, w: 9.2, h: 0.55,
    fontSize: 24, bold: true, color: RED, fontFace: "Calibri", charSpacing: 5, margin: 0
  });
  s.addShape(pres.shapes.RECTANGLE, {
    x: 0.4, y: 0.76, w: 3.5, h: 0.05, fill: { color: ACCENT }, line: { color: ACCENT }
  });

  const takeaways = [
    ["Blood Volume", "~5 L in adults; 7% of body weight"],
    ["Composition", "55% plasma + 45% formed elements (RBCs, WBCs, platelets)"],
    ["RBCs", "Biconcave, no nucleus; 120-day lifespan; carry O₂ via haemoglobin"],
    ["Haemoglobin", "4 globin chains + 4 haem groups; S-shaped O₂ dissociation curve"],
    ["WBCs", "5 types: neutrophils dominate; lymphocytes give specific immunity"],
    ["Platelets", "Smallest; essential for haemostasis and clot formation"],
    ["ABO System", "A, B, AB, O — based on surface antigens; O = universal donor"],
    ["Rh System", "D antigen; critical in pregnancy to prevent erythroblastosis fetalis"],
  ];

  takeaways.forEach(([k, v], i) => {
    const col = i < 4 ? 0 : 1;
    const row = i % 4;
    const x = 0.3 + col * 4.9;
    const y = 0.95 + row * 1.12;

    card(s, x, y, 4.55, 1.0, CARDBG);
    s.addShape(pres.shapes.RECTANGLE, {
      x, y, w: 0.09, h: 1.0, fill: { color: RED }, line: { color: RED }
    });
    s.addText(k, {
      x: x + 0.2, y: y + 0.12, w: 4.2, h: 0.3,
      fontSize: 10.5, bold: true, color: LTRED, fontFace: "Calibri", margin: 0
    });
    s.addText(v, {
      x: x + 0.2, y: y + 0.46, w: 4.2, h: 0.45,
      fontSize: 9.5, color: OFFWHITE, fontFace: "Calibri", margin: 0
    });
  });
}

// ─── WRITE FILE ──────────────────────────────────────────────
pres.writeFile({ fileName: "/home/daytona/workspace/blood-physiology-ppt/Blood_Physiology.pptx" })
  .then(() => console.log("✅ Done: Blood_Physiology.pptx"))
  .catch(err => { console.error("❌ Error:", err); process.exit(1); });

cd /home/daytona/workspace/blood-physiology-ppt && node create_pptx.js 2>&1

BHMS 1st year CBDC syllabus nerve muscle physiology topics

https://www.scribd.com/document/798554902/Physiology-CBDC-1s…

ls /home/daytona/workspace/ && mkdir -p /home/daytona/workspace/nerve-muscle-ppt

~/nerve-muscle-ppt/create_pptx.js

const pptxgen = require("pptxgenjs");

const pres = new pptxgen();
pres.layout = "LAYOUT_16x9";
pres.title = "Nerve Muscle Physiology";
pres.author = "Orris Medical";

// ─── COLOUR PALETTE (deep navy/teal — neuroscience feel) ─────
const NAVY      = "0B1A2E";   // dominant dark bg
const DARKNAVY  = "060F1C";   // deeper bg
const TEAL      = "0E7C7B";   // primary accent
const LTEAL     = "14A8A6";   // lighter teal
const CYAN      = "4ECDC4";   // highlight cyan
const WHITE     = "FFFFFF";
const OFFWHITE  = "E8F4F8";
const GRAY      = "A8C4CC";
const GOLD      = "F4D03F";
const ORANGE    = "E67E22";
const PURPLE    = "8E44AD";
const GREEN     = "27AE60";
const RED       = "E74C3C";
const CARD      = "112236";   // card bg
const CARD2     = "0D2A3A";   // alt card bg

// ─── HELPERS ─────────────────────────────────────────────────
function hdr(slide, title, subtitle) {
  slide.addShape(pres.shapes.RECTANGLE, { x:0, y:0, w:10, h:0.09, fill:{color:TEAL}, line:{color:TEAL} });
  slide.addShape(pres.shapes.RECTANGLE, { x:0, y:0.09, w:0.07, h:5.535, fill:{color:"094545"}, line:{color:"094545"} });
  slide.addText(title, { x:0.25, y:0.14, w:9.5, h:0.55, fontSize:21, bold:true, color:WHITE, fontFace:"Calibri", margin:0 });
  if (subtitle) slide.addText(subtitle, { x:0.25, y:0.68, w:9.5, h:0.28, fontSize:10, color:CYAN, fontFace:"Calibri", italic:true, margin:0 });
  slide.addShape(pres.shapes.RECTANGLE, { x:0, y:5.55, w:10, h:0.075, fill:{color:TEAL}, line:{color:TEAL} });
  slide.addText("BHMS 1st Year | Nerve Muscle Physiology | CBDC", { x:0.25, y:5.56, w:9.5, h:0.07, fontSize:6.5, color:NAVY, fontFace:"Calibri", margin:0 });
}

function card(slide, x, y, w, h, color) {
  slide.addShape(pres.shapes.RECTANGLE, { x, y, w, h, fill:{color:color||CARD}, line:{color:LTEAL, pt:0.9}, shadow:{type:"outer",color:"000000",blur:7,offset:3,angle:135,opacity:0.3} });
}

function dot(slide, x, y, color) {
  slide.addShape(pres.shapes.OVAL, { x, y, w:0.1, h:0.1, fill:{color:color||CYAN}, line:{color:color||CYAN} });
}

function badge(slide, x, y, w, h, text, bgColor, textColor) {
  slide.addShape(pres.shapes.RECTANGLE, { x, y, w, h, fill:{color:bgColor}, line:{color:bgColor} });
  slide.addText(text, { x, y, w, h, fontSize:8.5, bold:true, color:textColor||WHITE, fontFace:"Calibri", align:"center", valign:"middle", margin:0 });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 1 — TITLE
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKNAVY };

  // Decorative circles
  s.addShape(pres.shapes.OVAL, { x:6.0, y:-0.8, w:5.5, h:5.5, fill:{color:TEAL, transparency:88}, line:{color:TEAL, pt:1.5} });
  s.addShape(pres.shapes.OVAL, { x:6.8, y:-0.1, w:3.8, h:3.8, fill:{color:CYAN, transparency:92}, line:{color:CYAN, pt:0.8} });
  s.addShape(pres.shapes.OVAL, { x:7.5, y:2.5, w:2.5, h:2.5, fill:{color:TEAL, transparency:85}, line:{color:TEAL, pt:1.2} });

  // Top accent
  s.addShape(pres.shapes.RECTANGLE, { x:0, y:0, w:5.8, h:0.1, fill:{color:TEAL}, line:{color:TEAL} });
  s.addShape(pres.shapes.RECTANGLE, { x:0, y:0.1, w:0.08, h:5.52, fill:{color:"094545"}, line:{color:"094545"} });

  s.addText("NERVE MUSCLE", { x:0.35, y:0.65, w:7, h:1.15, fontSize:52, bold:true, color:WHITE, fontFace:"Calibri", charSpacing:3, margin:0 });
  s.addText("PHYSIOLOGY", { x:0.35, y:1.75, w:7, h:0.82, fontSize:44, bold:false, color:CYAN, fontFace:"Calibri", charSpacing:12, margin:0 });

  s.addShape(pres.shapes.RECTANGLE, { x:0.35, y:2.68, w:5.0, h:0.055, fill:{color:LTEAL}, line:{color:LTEAL} });

  s.addText("BHMS 1st Year  •  CBDC Syllabus  •  Human Physiology", { x:0.35, y:2.82, w:7, h:0.32, fontSize:11.5, color:GRAY, fontFace:"Calibri", margin:0 });

  const topics = ["Nerve Fibre Types","Membrane Potential","Action Potential","NMJ & Synapse","Muscle Contraction"];
  topics.forEach((t,i) => {
    s.addShape(pres.shapes.OVAL, { x:0.35+i*1.45, y:3.35, w:0.1, h:0.1, fill:{color:CYAN}, line:{color:CYAN} });
    s.addText(t, { x:0.52+i*1.45, y:3.32, w:1.35, h:0.28, fontSize:8.5, color:GRAY, fontFace:"Calibri", margin:0 });
  });

  s.addText("Orris Medical Education", { x:0.35, y:5.1, w:4, h:0.28, fontSize:9.5, color:TEAL, fontFace:"Calibri", margin:0 });
  s.addShape(pres.shapes.RECTANGLE, { x:0, y:5.55, w:10, h:0.075, fill:{color:TEAL}, line:{color:TEAL} });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 2 — SYLLABUS OVERVIEW
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: NAVY };
  hdr(s, "CBDC Syllabus — Nerve Muscle Physiology", "1st Year BHMS | Topics at a Glance");

  const topics = [
    { num:"01", title:"Properties of Nerve Fibres",   sub:"Excitability, conductivity, all-or-none law, refractory period", col:TEAL },
    { num:"02", title:"Classification of Nerve Fibres",sub:"Erlanger-Gasser (A,B,C) and Lloyd-Hunt classification", col:CYAN },
    { num:"03", title:"Resting Membrane Potential",    sub:"Ion distribution, Nernst equation, Na⁺/K⁺ pump", col:ORANGE },
    { num:"04", title:"Action Potential",              sub:"Generation, phases, propagation, saltatory conduction", col:PURPLE },
    { num:"05", title:"Neuromuscular Junction",        sub:"Structure, ACh release, end plate potential, drugs", col:GREEN },
    { num:"06", title:"Muscle Contraction",            sub:"Sliding filament theory, ECC, twitch, tetanus", col:RED },
    { num:"07", title:"Degeneration & Regeneration",   sub:"Wallerian degeneration, nerve repair, Bands of Büngner", col:GOLD },
    { num:"08", title:"Smooth Muscle Physiology",      sub:"Types, mechanism, differences from skeletal muscle", col:"2E86C1" },
  ];

  topics.forEach((t, i) => {
    const col = i < 4 ? 0 : 1;
    const row = i % 4;
    const x = 0.22 + col * 4.88;
    const y = 1.0 + row * 1.14;
    card(s, x, y, 4.65, 1.02, CARD);
    s.addShape(pres.shapes.RECTANGLE, { x, y, w:0.1, h:1.02, fill:{color:t.col}, line:{color:t.col} });
    s.addText(t.num, { x:x+0.18, y:y+0.08, w:0.5, h:0.38, fontSize:18, bold:true, color:t.col, fontFace:"Calibri", margin:0 });
    s.addText(t.title, { x:x+0.7, y:y+0.08, w:3.85, h:0.35, fontSize:10.5, bold:true, color:WHITE, fontFace:"Calibri", margin:0 });
    s.addText(t.sub, { x:x+0.7, y:y+0.54, w:3.85, h:0.38, fontSize:8.5, color:GRAY, fontFace:"Calibri", margin:0 });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 3 — PHYSIOLOGICAL PROPERTIES OF NERVE
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: NAVY };
  hdr(s, "Physiological Properties of Nerve Fibres", "Fundamental properties of excitable tissues");

  const props = [
    { name:"Excitability",    icon:"⚡", color:GOLD,   desc:"Ability to respond to an adequate (threshold) stimulus. Basis of nerve signalling." },
    { name:"Conductivity",    icon:"→", color:CYAN,   desc:"Ability to propagate an electrical impulse along the nerve membrane without decrement." },
    { name:"All-or-None Law", icon:"◉", color:ORANGE, desc:"If stimulus ≥ threshold → full AP. If below threshold → no AP. No partial responses." },
    { name:"Rhythmicity",     icon:"〰", color:GREEN,  desc:"Ability to generate spontaneous, repetitive impulses (prominent in cardiac & smooth muscle)." },
    { name:"Contractility",   icon:"↕", color:RED,    desc:"Ability to shorten in response to stimulus. Characteristic of muscle fibres." },
    { name:"Tonicity",        icon:"▣", color:PURPLE, desc:"State of partial, continuous contraction maintaining muscle tone at rest." },
  ];

  props.forEach((p, i) => {
    const col = i < 3 ? 0 : 1;
    const row = i % 3;
    const x = 0.22 + col * 4.9;
    const y = 1.05 + row * 1.47;
    card(s, x, y, 4.65, 1.3, CARD);
    s.addShape(pres.shapes.RECTANGLE, { x, y, w:4.65, h:0.33, fill:{color:p.color}, line:{color:p.color} });
    s.addText(p.icon + "  " + p.name, { x:x+0.1, y:y+0.02, w:4.4, h:0.3, fontSize:11, bold:true, color:WHITE, fontFace:"Calibri", margin:0 });
    s.addText(p.desc, { x:x+0.15, y:y+0.42, w:4.35, h:0.75, fontSize:9.5, color:OFFWHITE, fontFace:"Calibri", margin:0 });
  });

  // Refractory period box at bottom
  s.addText("📌  Refractory Period:  Absolute (~0.5–1 ms) — no response possible  |  Relative (~1–2 ms) — only stronger stimulus works", {
    x:0.22, y:5.08, w:9.55, h:0.3, fontSize:8.5, color:GOLD, fontFace:"Calibri", italic:true, margin:0
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 4 — CLASSIFICATION OF NERVE FIBRES
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: NAVY };
  hdr(s, "Classification of Nerve Fibres", "Erlanger & Gasser Classification — based on diameter and conduction velocity");

  card(s, 0.22, 1.0, 9.56, 3.98, CARD);

  // Table header
  const cols = ["Fibre", "Diameter (μm)", "Velocity (m/s)", "Myelination", "Function"];
  const colW = [0.7, 1.65, 1.65, 1.55, 4.0];
  const startX = 0.3;
  let cx = startX;
  cols.forEach((c, i) => {
    s.addShape(pres.shapes.RECTANGLE, { x:cx, y:1.05, w:colW[i]-0.05, h:0.38, fill:{color:TEAL}, line:{color:TEAL} });
    s.addText(c, { x:cx, y:1.06, w:colW[i]-0.05, h:0.35, fontSize:9, bold:true, color:WHITE, fontFace:"Calibri", align:"center", margin:0 });
    cx += colW[i];
  });

  const rows = [
    ["Aα","13–20","70–120","Myelinated","Skeletal muscle efferent, proprioception (Ia, Ib)", TEAL],
    ["Aβ","6–12","30–70","Myelinated","Touch, pressure, vibration", CYAN],
    ["Aγ","3–6","15–30","Myelinated","Muscle spindle (fusimotor fibres)", "2E86C1"],
    ["Aδ","1–5","5–30","Lightly myelinated","Sharp/fast pain, cold, touch", ORANGE],
    ["B","1–3","3–15","Lightly myelinated","Preganglionic autonomic fibres", PURPLE],
    ["C","0.2–1","0.5–2","Unmyelinated","Slow/burning pain, warmth, postganglionic autonomic", RED],
  ];

  rows.forEach((row, ri) => {
    const y = 1.48 + ri * 0.42;
    const rowBg = ri % 2 === 0 ? CARD : CARD2;
    let cx2 = startX;
    row.slice(0,5).forEach((cell, ci) => {
      s.addShape(pres.shapes.RECTANGLE, { x:cx2, y, w:colW[ci]-0.05, h:0.38, fill:{color:rowBg}, line:{color:"1A3A4A", pt:0.5} });
      const isFirst = ci === 0;
      s.addText(cell, { x:cx2+0.04, y:y+0.05, w:colW[ci]-0.1, h:0.28, fontSize:isFirst?11:8.8, bold:isFirst, color:isFirst?row[5]:OFFWHITE, fontFace:"Calibri", align:isFirst?"center":"left", margin:0 });
      cx2 += colW[ci];
    });
  });

  // Lloyd-Hunt summary
  card(s, 0.22, 5.06, 9.56, 0.38, "0A1E32");
  s.addText("Lloyd-Hunt Classification (Afferents):  Group I (Ia-muscle spindle, Ib-GTO)  |  Group II (secondary spindle)  |  Group III (Aδ-pain/cold)  |  Group IV (C-unmyelinated, slow pain)", {
    x:0.35, y:5.1, w:9.3, h:0.28, fontSize:8.5, color:GOLD, fontFace:"Calibri", margin:0
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 5 — RESTING MEMBRANE POTENTIAL
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: NAVY };
  hdr(s, "Resting Membrane Potential (RMP)", "The electrical potential difference across an unstimulated nerve membrane");

  // Left column — basis
  card(s, 0.22, 1.0, 5.5, 4.42, CARD);
  s.addText("Definition & Values", { x:0.4, y:1.08, w:5.1, h:0.35, fontSize:12.5, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });

  const vals = [
    ["Nerve (neuron)", "−70 mV"],
    ["Skeletal muscle", "−80 to −90 mV"],
    ["Cardiac muscle", "−90 mV"],
    ["Smooth muscle", "−50 to −55 mV"],
  ];
  vals.forEach(([k,v],i) => {
    const y = 1.5 + i*0.45;
    s.addShape(pres.shapes.RECTANGLE, { x:0.38, y, w:5.2, h:0.38, fill:{color:i%2===0?CARD:CARD2}, line:{color:CARD2} });
    s.addText(k, { x:0.48, y:y+0.06, w:2.5, h:0.26, fontSize:9.5, color:GRAY, fontFace:"Calibri", margin:0 });
    s.addText(v, { x:3.0, y:y+0.06, w:2.5, h:0.26, fontSize:12, bold:true, color:GOLD, fontFace:"Calibri", margin:0 });
  });

  s.addText("Basis of RMP", { x:0.4, y:3.38, w:5.1, h:0.35, fontSize:12, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });
  const basis = [
    ["1", "Unequal ion distribution", "High K⁺ & proteins inside; high Na⁺ & Cl⁻ outside"],
    ["2", "Selective permeability", "At rest: K⁺ permeability >> Na⁺ permeability (50–100×)"],
    ["3", "K⁺ diffuses out", "Interior becomes negative; equilibrium reached at E_K"],
    ["4", "Na⁺/K⁺-ATPase pump", "3 Na⁺ out / 2 K⁺ in → electrogenic contribution (~−4 mV)"],
  ];
  basis.forEach(([n,bold,desc],i) => {
    dot(s, 0.42, 3.83+i*0.37, CYAN);
    s.addText(bold+": ", { x:0.6, y:3.8+i*0.37, w:1.7, h:0.28, fontSize:9, bold:true, color:LTEAL, fontFace:"Calibri", margin:0 });
    s.addText(desc, { x:2.28, y:3.8+i*0.37, w:3.3, h:0.28, fontSize:9, color:OFFWHITE, fontFace:"Calibri", margin:0 });
  });

  // Right column — ion diagram
  card(s, 5.9, 1.0, 3.88, 4.42, CARD2);
  s.addText("Ion Distribution", { x:6.05, y:1.08, w:3.6, h:0.35, fontSize:12.5, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });

  // Outside box
  s.addShape(pres.shapes.RECTANGLE, { x:6.0, y:1.5, w:3.7, h:1.08, fill:{color:"0A2535"}, line:{color:LTEAL, pt:1} });
  s.addText("OUTSIDE (ECF)", { x:6.1, y:1.52, w:3.5, h:0.3, fontSize:9, bold:true, color:GRAY, fontFace:"Calibri", align:"center", margin:0 });
  s.addText("Na⁺  142 mEq/L  •  Cl⁻  103 mEq/L  •  K⁺  4 mEq/L", { x:6.05, y:1.85, w:3.65, h:0.28, fontSize:9, color:OFFWHITE, fontFace:"Calibri", align:"center", margin:0 });

  // Membrane
  s.addShape(pres.shapes.RECTANGLE, { x:6.0, y:2.62, w:3.7, h:0.38, fill:{color:TEAL}, line:{color:LTEAL, pt:1} });
  s.addText("⬛ MEMBRANE (selectively permeable)", { x:6.05, y:2.65, w:3.65, h:0.28, fontSize:8.5, bold:true, color:WHITE, fontFace:"Calibri", align:"center", margin:0 });

  // Inside box
  s.addShape(pres.shapes.RECTANGLE, { x:6.0, y:3.04, w:3.7, h:1.08, fill:{color:"0A2535"}, line:{color:LTEAL, pt:1} });
  s.addText("INSIDE (ICF)  [ −70 mV ]", { x:6.1, y:3.06, w:3.5, h:0.3, fontSize:9, bold:true, color:GOLD, fontFace:"Calibri", align:"center", margin:0 });
  s.addText("K⁺  140 mEq/L  •  Proteins⁻  high  •  Na⁺  14 mEq/L", { x:6.05, y:3.38, w:3.65, h:0.28, fontSize:9, color:OFFWHITE, fontFace:"Calibri", align:"center", margin:0 });

  // Nernst equation
  card(s, 5.9, 4.2, 3.88, 1.12, "0A1E2E");
  s.addText("Nernst Equation", { x:6.08, y:4.25, w:3.6, h:0.28, fontSize:9.5, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });
  s.addText("E_ion = (RT/zF) × ln([ion]out / [ion]in)", { x:6.08, y:4.57, w:3.6, h:0.28, fontSize:10, color:GOLD, fontFace:"Calibri", italic:true, margin:0 });
  s.addText("E_K = −94 mV  |  E_Na = +61 mV  |  Actual RMP = −70 mV (GHK equation)", { x:6.08, y:4.88, w:3.65, h:0.28, fontSize:8, color:GRAY, fontFace:"Calibri", margin:0 });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 6 — ACTION POTENTIAL
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: NAVY };
  hdr(s, "Action Potential (AP)", "Rapid, transient, self-propagating change in membrane potential");

  // Left — phases description
  card(s, 0.22, 1.0, 5.35, 4.42, CARD);
  s.addText("Phases of Action Potential", { x:0.4, y:1.07, w:5.0, h:0.38, fontSize:12.5, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });

  const phases = [
    { name:"Resting Phase", val:"−70 mV", color:GRAY,   desc:"Na⁺ channels closed. Resting K⁺ leak channels open. Stable baseline." },
    { name:"Depolarisation", val:"−70→+35 mV", color:RED,    desc:"Threshold (−55 mV) reached → voltage-gated Na⁺ channels OPEN → Na⁺ rushes in → rapid rise." },
    { name:"Overshoot",      val:"+35 mV", color:ORANGE, desc:"Membrane potential exceeds 0 mV. Na⁺ channels begin to inactivate (h-gate closes)." },
    { name:"Repolarisation", val:"+35→−70 mV", color:GREEN,  desc:"Voltage-gated K⁺ channels OPEN → K⁺ flows out → membrane potential falls." },
    { name:"Hyperpolarisation",val:"−70→−80 mV", color:PURPLE, desc:"K⁺ channels close slowly → brief dip below RMP (after-potential). Followed by return to −70 mV." },
  ];

  phases.forEach((p, i) => {
    const y = 1.54 + i * 0.75;
    s.addShape(pres.shapes.RECTANGLE, { x:0.3, y, w:0.08, h:0.62, fill:{color:p.color}, line:{color:p.color} });
    s.addText(p.name, { x:0.46, y:y+0.04, w:2.5, h:0.26, fontSize:9.5, bold:true, color:p.color, fontFace:"Calibri", margin:0 });
    badge(s, 2.95, y+0.04, 1.48, 0.24, p.val, p.color, WHITE);
    s.addText(p.desc, { x:0.46, y:y+0.32, w:4.95, h:0.3, fontSize:8.5, color:OFFWHITE, fontFace:"Calibri", margin:0 });
  });

  // Right — key values + propagation
  card(s, 5.75, 1.0, 4.03, 2.18, CARD2);
  s.addText("Key Values", { x:5.9, y:1.07, w:3.7, h:0.33, fontSize:12, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });
  const kvs = [
    ["RMP",              "−70 mV"],
    ["Threshold",        "−55 mV"],
    ["Peak (overshoot)", "+30 to +40 mV"],
    ["AP duration",      "~1 ms (nerve)"],
    ["Abs. refractory",  "~0.5–1 ms"],
    ["Rel. refractory",  "~1–2 ms"],
  ];
  kvs.forEach(([k,v],i) => {
    s.addText(k, { x:5.88, y:1.47+i*0.27, w:2.0, h:0.24, fontSize:9, color:GRAY, fontFace:"Calibri", margin:0 });
    s.addText(v, { x:7.85, y:1.47+i*0.27, w:1.85, h:0.24, fontSize:9.5, bold:true, color:GOLD, fontFace:"Calibri", margin:0 });
  });

  card(s, 5.75, 3.28, 4.03, 2.14, CARD2);
  s.addText("Propagation", { x:5.9, y:3.35, w:3.7, h:0.33, fontSize:12, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });

  const propItems = [
    ["Continuous conduction", "Unmyelinated fibres — slow (~0.5–2 m/s). Current flows along entire axon membrane."],
    ["Saltatory conduction",  "Myelinated fibres — AP jumps from node to node of Ranvier. Fast (70–120 m/s). Energy-efficient."],
    ["All-or-None",          "AP is full amplitude or absent. Intensity coded by frequency, not amplitude."],
  ];
  propItems.forEach(([title, desc],i) => {
    dot(s, 5.88, 3.82+i*0.5, CYAN);
    s.addText(title+": ", { x:6.06, y:3.79+i*0.5, w:1.95, h:0.26, fontSize:9, bold:true, color:LTEAL, fontFace:"Calibri", margin:0 });
    s.addText(desc, { x:5.88, y:4.03+i*0.5, w:3.82, h:0.26, fontSize:8.5, color:OFFWHITE, fontFace:"Calibri", margin:0 });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 7 — NEUROMUSCULAR JUNCTION
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: NAVY };
  hdr(s, "Neuromuscular Junction (NMJ)", "Synapse between motor neuron axon terminal and skeletal muscle fibre");

  // Structure card
  card(s, 0.22, 1.0, 4.5, 4.42, CARD);
  s.addText("Structure of NMJ", { x:0.4, y:1.07, w:4.2, h:0.35, fontSize:12, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });

  const structItems = [
    ["Presynaptic terminal", "Axon terminal / bouton; ~300,000 synaptic vesicles; mitochondria (ATP for ACh synthesis)"],
    ["Synaptic vesicles",   "Each contains ~10,000 molecules of Acetylcholine (ACh)"],
    ["Synaptic cleft",      "20–30 nm wide; contains Acetylcholinesterase (AChE)"],
    ["Motor end plate",     "Postsynaptic membrane with junctional folds (subneural clefts)"],
    ["ACh receptors",       "Nicotinic receptors (ligand-gated ion channels) at the junctional folds"],
    ["Voltage-gated Na⁺",  "Channels in subneural clefts — generate muscle AP on stimulation"],
  ];
  structItems.forEach(([title,desc],i) => {
    const y = 1.5 + i*0.65;
    s.addShape(pres.shapes.RECTANGLE, { x:0.32, y, w:0.07, h:0.52, fill:{color:i%2===0?TEAL:ORANGE}, line:{color:i%2===0?TEAL:ORANGE} });
    s.addText(title, { x:0.48, y:y+0.04, w:4.1, h:0.22, fontSize:9.5, bold:true, color:i%2===0?CYAN:GOLD, fontFace:"Calibri", margin:0 });
    s.addText(desc, { x:0.48, y:y+0.26, w:4.1, h:0.28, fontSize:8.5, color:OFFWHITE, fontFace:"Calibri", margin:0 });
  });

  // Events card
  card(s, 4.9, 1.0, 4.88, 4.42, CARD2);
  s.addText("Events at NMJ — Step by Step", { x:5.05, y:1.07, w:4.6, h:0.35, fontSize:12, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });

  const steps = [
    ["1", TEAL,   "AP arrives at axon terminal"],
    ["2", CYAN,   "Voltage-gated Ca²⁺ channels open → Ca²⁺ enters (100× rise)"],
    ["3", GREEN,  "Ca²⁺ → exocytosis of ~125 ACh vesicles into cleft"],
    ["4", ORANGE, "ACh binds nicotinic receptors on motor end plate"],
    ["5", PURPLE, "Na⁺/K⁺ flow → End Plate Potential (EPP) generated"],
    ["6", RED,    "EPP → threshold → Muscle Action Potential"],
    ["7", GOLD,   "AChE hydrolyses ACh → acetate + choline; choline recycled"],
  ];
  steps.forEach(([n,col,text],i) => {
    const y = 1.52 + i*0.55;
    s.addShape(pres.shapes.OVAL, { x:5.05, y, w:0.32, h:0.32, fill:{color:col}, line:{color:col} });
    s.addText(n, { x:5.05, y, w:0.32, h:0.32, fontSize:10, bold:true, color:WHITE, fontFace:"Calibri", align:"center", valign:"middle", margin:0 });
    // Arrow
    if (i<6) s.addText("↓", { x:5.14, y:y+0.32, w:0.18, h:0.2, fontSize:9, color:col, fontFace:"Calibri", align:"center", margin:0 });
    s.addText(text, { x:5.45, y:y+0.03, w:4.25, h:0.3, fontSize:9.5, color:OFFWHITE, fontFace:"Calibri", margin:0 });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 8 — DRUGS AT NMJ & MYASTHENIA GRAVIS
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: NAVY };
  hdr(s, "Drugs at NMJ & Clinical Disorders", "Pharmacology of neuromuscular junction");

  // Drugs table
  card(s, 0.22, 1.0, 9.55, 2.75, CARD);
  s.addText("Drugs Acting on NMJ", { x:0.4, y:1.07, w:9.2, h:0.35, fontSize:12.5, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });

  const drugCols = ["Drug", "Mechanism", "Effect", "Clinical Use"];
  const drugColW = [2.2, 2.8, 2.4, 2.3];
  let dcx = 0.3;
  drugCols.forEach((h,i) => {
    s.addShape(pres.shapes.RECTANGLE, { x:dcx, y:1.48, w:drugColW[i]-0.06, h:0.3, fill:{color:TEAL}, line:{color:TEAL} });
    s.addText(h, { x:dcx+0.04, y:1.49, w:drugColW[i]-0.1, h:0.28, fontSize:9, bold:true, color:WHITE, fontFace:"Calibri", align:"center", margin:0 });
    dcx += drugColW[i];
  });
  const drugs = [
    ["Neostigmine / Physostigmine", "Inhibits AChE (reversible)", "↑ ACh in cleft → spasm", "Myasthenia Gravis Tx"],
    ["Succinylcholine", "Depolarising block (nicotinic agonist)", "Flaccid paralysis (sustained depol.)", "Anaesthetic muscle relaxant"],
    ["Curare (tubocurarine)", "Competitive nicotinic antagonist", "Non-depolarising paralysis", "Surgical muscle relaxation"],
    ["Organophosphates", "Irreversibly inhibit AChE", "Cholinergic crisis, death", "Insecticides, nerve agents"],
    ["Botulinum toxin", "Blocks ACh vesicle release", "Flaccid paralysis", "Cosmetic, spasticity, strabismus"],
  ];
  drugs.forEach((row, ri) => {
    const y = 1.82 + ri * 0.36;
    const rowBg = ri%2===0?CARD:CARD2;
    let cx2 = 0.3;
    row.forEach((cell,ci) => {
      s.addShape(pres.shapes.RECTANGLE, { x:cx2, y, w:drugColW[ci]-0.06, h:0.33, fill:{color:rowBg}, line:{color:"1A3A4A",pt:0.5} });
      s.addText(cell, { x:cx2+0.06, y:y+0.05, w:drugColW[ci]-0.12, h:0.24, fontSize:8.5, bold:ci===0, color:ci===0?GOLD:OFFWHITE, fontFace:"Calibri", margin:0 });
      cx2 += drugColW[ci];
    });
  });

  // Myasthenia Gravis
  card(s, 0.22, 3.88, 9.55, 1.5, "0A1E2E");
  s.addShape(pres.shapes.RECTANGLE, { x:0.22, y:3.88, w:9.55, h:0.35, fill:{color:RED}, line:{color:RED} });
  s.addText("⚠  Myasthenia Gravis — Clinical Pearl", { x:0.35, y:3.9, w:9.3, h:0.3, fontSize:11, bold:true, color:WHITE, fontFace:"Calibri", margin:0 });
  const mgItems = [
    "Autoimmune disease: Antibodies against NICOTINIC ACh receptors",
    "↓ Functional receptors → ↓ EPP amplitude → Muscle weakness & fatigability",
    "Hallmark: Weakness WORSE with activity, improves with rest",
    "Treatment: Neostigmine (anticholinesterase) | Thymectomy | Immunosuppressants | Anti-CD20",
  ];
  mgItems.forEach((txt,i) => {
    dot(s, 0.35, 4.32+i*0.27, RED);
    s.addText(txt, { x:0.52, y:4.29+i*0.27, w:9.15, h:0.25, fontSize:9, color:OFFWHITE, fontFace:"Calibri", margin:0 });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 9 — MUSCLE CONTRACTION
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: NAVY };
  hdr(s, "Skeletal Muscle Contraction", "Sliding Filament Theory & Excitation-Contraction Coupling");

  // Left — Sarcomere structure
  card(s, 0.22, 1.0, 4.65, 4.42, CARD);
  s.addText("Sarcomere — Functional Unit", { x:0.4, y:1.07, w:4.3, h:0.35, fontSize:11.5, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });

  const sarcomere = [
    ["Sarcomere", "Region between two Z-lines; basic contractile unit"],
    ["Thick filaments", "Myosin — has globular head (ATPase activity)"],
    ["Thin filaments", "Actin + Troponin + Tropomyosin"],
    ["A band", "Dark band; contains thick (+ thin) filaments; CONSTANT width"],
    ["I band", "Light band; only thin filaments; SHORTENS during contraction"],
    ["H zone", "Only thick filaments in centre; SHORTENS during contraction"],
    ["Z line", "Anchors thin filaments; defines sarcomere boundary"],
    ["M line", "Centre of sarcomere; connects thick filaments"],
  ];
  sarcomere.forEach(([term,def],i) => {
    const y = 1.5 + i*0.48;
    const bg = i%2===0?CARD:CARD2;
    s.addShape(pres.shapes.RECTANGLE, { x:0.3, y, w:4.48, h:0.42, fill:{color:bg}, line:{color:bg} });
    s.addText(term, { x:0.4, y:y+0.08, w:1.6, h:0.26, fontSize:9, bold:true, color:LTEAL, fontFace:"Calibri", margin:0 });
    s.addText(def, { x:2.05, y:y+0.08, w:2.6, h:0.3, fontSize:8.5, color:OFFWHITE, fontFace:"Calibri", margin:0 });
  });

  // Right — ECC + Sliding Filament
  card(s, 5.05, 1.0, 4.73, 2.12, CARD2);
  s.addText("Excitation-Contraction Coupling (ECC)", { x:5.2, y:1.07, w:4.5, h:0.35, fontSize:11, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });
  const ecc = [
    "Muscle AP → T-tubules (transverse tubules)",
    "T-tubules → activate Dihydropyridine receptors",
    "DHP receptors → open Ryanodine receptors on SR",
    "Ca²⁺ released from Sarcoplasmic Reticulum",
    "Ca²⁺ binds Troponin C → tropomyosin moves",
    "Actin binding sites EXPOSED",
    "Myosin heads bind actin → cross-bridge cycle",
  ];
  ecc.forEach((step,i) => {
    dot(s, 5.2, 1.5+i*0.27, i===5?GREEN:TEAL);
    s.addText(step, { x:5.38, y:1.47+i*0.27, w:4.3, h:0.24, fontSize:8.8, color:i===5?GOLD:OFFWHITE, fontFace:"Calibri", bold:i===5, margin:0 });
  });

  card(s, 5.05, 3.22, 4.73, 2.2, CARD2);
  s.addText("Cross-Bridge Cycle (Sliding Filament)", { x:5.2, y:3.29, w:4.5, h:0.33, fontSize:11, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });
  const cb = [
    ["Step 1","Myosin head (ADP+Pi) attaches to ACTIN — cross-bridge formed"],
    ["Step 2","POWER STROKE — head pivots 45° → actin pulled → sarcomere shortens"],
    ["Step 3","ATP binds myosin → head DETACHES from actin (rigor mortis = no ATP)"],
    ["Step 4","ATP hydrolysis → ADP + Pi; myosin head returns to original position (cocked)"],
    ["Step 5","Cycle repeats as long as Ca²⁺ and ATP are available"],
  ];
  cb.forEach(([n,desc],i) => {
    badge(s, 5.18, 3.68+i*0.32, 0.52, 0.22, n, i===1?RED:TEAL, WHITE);
    s.addText(desc, { x:5.78, y:3.67+i*0.32, w:3.92, h:0.28, fontSize:8.5, color:i===1?GOLD:OFFWHITE, fontFace:"Calibri", bold:i===1, margin:0 });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 10 — MUSCLE MECHANICS
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: NAVY };
  hdr(s, "Muscle Mechanics & Types of Contraction", "Twitch, summation, tetanus, and motor unit");

  // Contraction types
  card(s, 0.22, 1.0, 4.65, 2.08, CARD);
  s.addText("Types of Contraction", { x:0.4, y:1.07, w:4.3, h:0.33, fontSize:12, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });
  const contTypes = [
    ["Isotonic",  GREEN,  "Muscle shortens; tension remains constant. E.g., lifting a weight."],
    ["Isometric", ORANGE, "Tension develops; no shortening. E.g., pushing a wall."],
    ["Eccentric", PURPLE, "Muscle lengthens while generating tension. E.g., lowering a weight."],
  ];
  contTypes.forEach(([n,col,d],i) => {
    s.addShape(pres.shapes.RECTANGLE, { x:0.3, y:1.45+i*0.5, w:4.5, h:0.42, fill:{color:CARD2}, line:{color:CARD2} });
    badge(s, 0.35, 1.5+i*0.5, 0.95, 0.28, n, col, WHITE);
    s.addText(d, { x:1.38, y:1.52+i*0.5, w:3.35, h:0.28, fontSize:8.8, color:OFFWHITE, fontFace:"Calibri", margin:0 });
  });

  // Twitch-Tetanus
  card(s, 0.22, 3.18, 4.65, 2.25, CARD);
  s.addText("Twitch → Summation → Tetanus", { x:0.4, y:3.25, w:4.3, h:0.33, fontSize:11.5, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });
  const tetItems = [
    ["Twitch", GRAY, "Single AP → single brief contraction & relaxation cycle"],
    ["Summation", ORANGE, "2nd stimulus before relaxation → greater force (temporal summation)"],
    ["Unfused Tetanus", GREEN, "~30–40 Hz → sustained but incomplete (serrated) contraction"],
    ["Fused Tetanus", RED, "~60–80 Hz → smooth, maximal, sustained contraction"],
  ];
  tetItems.forEach(([n,col,d],i) => {
    dot(s, 0.35, 3.68+i*0.38, col);
    s.addText(n+":", { x:0.52, y:3.65+i*0.38, w:1.45, h:0.28, fontSize:9.5, bold:true, color:col, fontFace:"Calibri", margin:0 });
    s.addText(d, { x:1.95, y:3.65+i*0.38, w:2.85, h:0.28, fontSize:8.8, color:OFFWHITE, fontFace:"Calibri", margin:0 });
  });

  // Motor Unit + Fibre types
  card(s, 5.05, 1.0, 4.73, 2.18, CARD2);
  s.addText("Motor Unit", { x:5.2, y:1.07, w:4.5, h:0.33, fontSize:12, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });
  const muItems = [
    "1 motor neuron + ALL muscle fibres it innervates",
    "Small motor units (e.g., eye): 3–6 fibres → fine control",
    "Large motor units (quadriceps): 1000s → coarse/powerful",
    "Recruitment: more motor units = greater force",
    "Size principle: small (slow) units recruited first",
  ];
  muItems.forEach((txt,i) => {
    dot(s, 5.2, 1.52+i*0.3, TEAL);
    s.addText(txt, { x:5.38, y:1.49+i*0.3, w:4.3, h:0.28, fontSize:9, color:OFFWHITE, fontFace:"Calibri", margin:0 });
  });

  // Fibre types table
  card(s, 5.05, 3.28, 4.73, 2.14, CARD2);
  s.addText("Muscle Fibre Types", { x:5.2, y:3.35, w:4.5, h:0.33, fontSize:12, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });
  const ftHeader = ["Feature","Type I (Slow)","Type II (Fast)"];
  const ftColW = [1.4, 1.5, 1.6];
  let ftx = 5.12;
  ftHeader.forEach((h,i) => {
    s.addShape(pres.shapes.RECTANGLE, { x:ftx, y:3.74, w:ftColW[i]-0.05, h:0.28, fill:{color:TEAL}, line:{color:TEAL} });
    s.addText(h, { x:ftx, y:3.75, w:ftColW[i]-0.05, h:0.25, fontSize:8, bold:true, color:WHITE, fontFace:"Calibri", align:"center", margin:0 });
    ftx += ftColW[i];
  });
  const ftRows = [
    ["Speed","Slow","Fast"],
    ["Metabolism","Oxidative","Glycolytic"],
    ["Fatigue","Resistant","Fatigable"],
    ["Colour","Red","White"],
    ["Function","Posture/endurance","Power/sprinting"],
  ];
  ftRows.forEach((row,ri) => {
    const y = 4.06 + ri*0.26;
    const bg = ri%2===0?CARD:CARD2;
    let cx3 = 5.12;
    row.forEach((cell,ci) => {
      s.addShape(pres.shapes.RECTANGLE, { x:cx3, y, w:ftColW[ci]-0.05, h:0.24, fill:{color:bg}, line:{color:"1A3A4A",pt:0.4} });
      s.addText(cell, { x:cx3+0.04, y:y+0.04, w:ftColW[ci]-0.08, h:0.18, fontSize:8, color:ci===0?LTEAL:OFFWHITE, fontFace:"Calibri", bold:ci===0, margin:0 });
      cx3 += ftColW[ci];
    });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 11 — DEGENERATION & REGENERATION
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: NAVY };
  hdr(s, "Degeneration & Regeneration of Nerve Fibres", "Wallerian degeneration and peripheral nerve repair");

  card(s, 0.22, 1.0, 5.55, 4.42, CARD);
  s.addText("Wallerian Degeneration (Distal to cut)", { x:0.4, y:1.07, w:5.2, h:0.35, fontSize:12, bold:true, color:ORANGE, fontFace:"Calibri", margin:0 });

  const wdEvents = [
    ["Day 1–3",   RED,    "Axon and myelin disintegrate DISTAL to the injury site"],
    ["Day 3–5",   ORANGE, "Schwann cells proliferate; phagocytose axon/myelin debris"],
    ["Day 5–7",   GOLD,   "Macrophages assist in clearance of debris"],
    ["Day 7+",    GREEN,  "Empty endoneurial tube (Schwann cell columns) remains"],
    ["Cell body", PURPLE, "Chromatolysis: Nissl substance dissolves, nucleus displaced peripherally"],
  ];
  wdEvents.forEach(([time,col,desc],i) => {
    const y = 1.5 + i*0.6;
    badge(s, 0.35, y+0.08, 0.85, 0.25, time, col, WHITE);
    s.addText(desc, { x:1.28, y:y+0.05, w:4.35, h:0.45, fontSize:9.5, color:OFFWHITE, fontFace:"Calibri", margin:0 });
    if(i<4) s.addShape(pres.shapes.RECTANGLE, { x:0.7, y:y+0.38, w:0.02, h:0.22, fill:{color:col}, line:{color:col} });
  });

  s.addText("Regeneration", { x:0.4, y:4.58, w:5.2, h:0.3, fontSize:11, bold:true, color:GREEN, fontFace:"Calibri", margin:0 });
  s.addText("Rate: ~1–3 mm/day (1 inch/month)  |  PNS can regenerate; CNS generally cannot  |  Guided by Bands of Büngner (Schwann cell tubes)", {
    x:0.4, y:4.9, w:5.2, h:0.3, fontSize:8.5, color:GRAY, fontFace:"Calibri", margin:0
  });

  // Right — Seddon classification
  card(s, 5.95, 1.0, 3.83, 4.42, CARD2);
  s.addText("Seddon's Classification of Nerve Injury", { x:6.05, y:1.07, w:3.6, h:0.45, fontSize:11, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });

  const seddon = [
    { name:"Neuropraxia", col:GREEN, desc:"Conduction block only. Axon & endoneurium intact. No structural damage.", recovery:"Complete recovery in days–weeks." },
    { name:"Axonotmesis", col:ORANGE, desc:"Axon cut but endoneurium intact. Wallerian degeneration occurs distally.", recovery:"Good recovery (months). Guided by intact endoneurium." },
    { name:"Neurotmesis", col:RED, desc:"Complete nerve transection. All layers severed (axon + myelin + connective tissue).", recovery:"Poor without surgery. Requires nerve repair/grafting." },
  ];
  seddon.forEach((item,i) => {
    const y = 1.6 + i*1.3;
    card(s, 6.0, y, 3.7, 1.18, CARD);
    s.addShape(pres.shapes.RECTANGLE, { x:6.0, y, w:3.7, h:0.32, fill:{color:item.col}, line:{color:item.col} });
    s.addText(item.name, { x:6.08, y:y+0.02, w:3.55, h:0.28, fontSize:11, bold:true, color:WHITE, fontFace:"Calibri", margin:0 });
    s.addText(item.desc, { x:6.08, y:y+0.38, w:3.55, h:0.42, fontSize:9, color:OFFWHITE, fontFace:"Calibri", margin:0 });
    s.addText("↳ "+item.recovery, { x:6.08, y:y+0.82, w:3.55, h:0.28, fontSize:8.5, color:GOLD, fontFace:"Calibri", italic:true, margin:0 });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 12 — SMOOTH MUSCLE
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: NAVY };
  hdr(s, "Smooth Muscle Physiology", "Involuntary muscle found in visceral organs");

  card(s, 0.22, 1.0, 4.65, 2.1, CARD);
  s.addText("Types of Smooth Muscle", { x:0.4, y:1.07, w:4.3, h:0.33, fontSize:12, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });
  const smTypes = [
    { name:"Multi-unit", col:TEAL, desc:"Each fibre independently innervated. E.g., ciliary muscle, iris, piloerector muscles. Neural control dominant." },
    { name:"Unitary (Visceral/Single-unit)", col:ORANGE, desc:"Fibres connected by GAP JUNCTIONS → contract as a unit. Spontaneous activity. E.g., GI tract, uterus, ureter, bladder." },
  ];
  smTypes.forEach(({name,col,desc},i) => {
    const y = 1.48 + i*0.75;
    s.addShape(pres.shapes.RECTANGLE, { x:0.3, y, w:4.48, h:0.62, fill:{color:CARD2}, line:{color:CARD2} });
    badge(s, 0.35, y+0.1, 1.5, 0.26, name, col, WHITE);
    s.addText(desc, { x:1.92, y:y+0.07, w:2.75, h:0.52, fontSize:8.8, color:OFFWHITE, fontFace:"Calibri", margin:0 });
  });

  card(s, 0.22, 3.18, 4.65, 2.24, CARD);
  s.addText("Contraction Mechanism", { x:0.4, y:3.25, w:4.3, h:0.33, fontSize:12, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });
  const smMech = [
    "Ca²⁺ enters from ECF (L-type channels) or released from SR",
    "Ca²⁺ + Calmodulin → Ca-Calmodulin complex",
    "Activates Myosin Light Chain Kinase (MLCK)",
    "MLCK phosphorylates myosin → cross-bridge cycling",
    "Relaxation: MLCK inactivated; myosin phosphatase dephosphorylates",
    "NO TROPONIN in smooth muscle (unlike skeletal)",
  ];
  smMech.forEach((txt,i) => {
    dot(s, 0.35, 3.68+i*0.3, i===5?RED:TEAL);
    s.addText(txt, { x:0.52, y:3.65+i*0.3, w:4.25, h:0.28, fontSize:8.8, bold:i===5, color:i===5?GOLD:OFFWHITE, fontFace:"Calibri", margin:0 });
  });

  // Comparison table
  card(s, 5.05, 1.0, 4.73, 4.42, CARD2);
  s.addText("Skeletal vs Smooth Muscle", { x:5.2, y:1.07, w:4.5, h:0.33, fontSize:12, bold:true, color:CYAN, fontFace:"Calibri", margin:0 });

  const compHeader = ["Feature","Skeletal","Smooth"];
  const compColW = [1.55, 1.55, 1.55];
  let compX = 5.1;
  compHeader.forEach((h,i) => {
    s.addShape(pres.shapes.RECTANGLE, { x:compX, y:1.46, w:compColW[i]-0.05, h:0.3, fill:{color:TEAL}, line:{color:TEAL} });
    s.addText(h, { x:compX, y:1.47, w:compColW[i]-0.05, h:0.28, fontSize:8.5, bold:true, color:WHITE, fontFace:"Calibri", align:"center", margin:0 });
    compX += compColW[i];
  });
  const compRows = [
    ["Control","Voluntary","Involuntary"],
    ["Speed","Fast","Slow"],
    ["Troponin","Present","ABSENT"],
    ["Trigger","Ca²⁺+Troponin","Ca²⁺+Calmodulin/MLCK"],
    ["T-tubules","Present","Absent (caveolae)"],
    ["SR","Well developed","Less developed"],
    ["Striations","Yes","No"],
    ["Nuclei","Multi-nucleate","Single nucleus"],
    ["Fatigue","Fatigable","Resistant"],
    ["Regulation","Neural only","Neural+hormonal+local"],
  ];
  compRows.forEach((row,ri) => {
    const y = 1.8 + ri*0.36;
    const bg = ri%2===0?CARD:CARD2;
    let cx4 = 5.1;
    row.forEach((cell,ci) => {
      s.addShape(pres.shapes.RECTANGLE, { x:cx4, y, w:compColW[ci]-0.05, h:0.32, fill:{color:bg}, line:{color:"1A3A4A",pt:0.4} });
      const isHighlight = (cell==="ABSENT"||cell==="Yes"||cell==="No");
      s.addText(cell, { x:cx4+0.04, y:y+0.06, w:compColW[ci]-0.08, h:0.22, fontSize:8, bold:ci===0||isHighlight, color:ci===0?LTEAL:(isHighlight?RED:OFFWHITE), fontFace:"Calibri", margin:0 });
      cx4 += compColW[ci];
    });
  });
}

// ═══════════════════════════════════════════════════════════════
// SLIDE 13 — SUMMARY / KEY TAKEAWAYS
// ═══════════════════════════════════════════════════════════════
{
  const s = pres.addSlide();
  s.background = { color: DARKNAVY };

  s.addShape(pres.shapes.RECTANGLE, { x:0, y:0, w:10, h:0.09, fill:{color:TEAL}, line:{color:TEAL} });
  s.addShape(pres.shapes.RECTANGLE, { x:0, y:5.55, w:10, h:0.075, fill:{color:TEAL}, line:{color:TEAL} });
  // Decorative
  s.addShape(pres.shapes.OVAL, { x:7.5, y:3.0, w:3.5, h:3.5, fill:{color:TEAL, transparency:91}, line:{color:TEAL, pt:1} });

  s.addText("KEY TAKEAWAYS", { x:0.35, y:0.18, w:9.2, h:0.5, fontSize:22, bold:true, color:WHITE, fontFace:"Calibri", charSpacing:5, margin:0 });
  s.addShape(pres.shapes.RECTANGLE, { x:0.35, y:0.68, w:3.8, h:0.05, fill:{color:CYAN}, line:{color:CYAN} });

  const takeaways = [
    { topic:"RMP",                val:"−70 mV (nerve); maintained by Na⁺/K⁺ pump + K⁺ permeability", col:TEAL },
    { topic:"Action Potential",   val:"Threshold −55 mV; Na⁺ in (depol.) → K⁺ out (repol.); All-or-None", col:CYAN },
    { topic:"Saltatory Conduction",val:"AP jumps node to node in myelinated fibres; 70–120 m/s", col:GREEN },
    { topic:"Nerve Fibre Types",  val:"Aα fastest (70–120 m/s); C slowest (0.5–2 m/s); B = preganglionic autonomic", col:ORANGE },
    { topic:"NMJ Transmitter",    val:"Acetylcholine → nicotinic receptors → EPP → Muscle AP", col:PURPLE },
    { topic:"ECC Messenger",      val:"Ca²⁺ released from SR → binds Troponin C → exposes actin sites", col:RED },
    { topic:"Sliding Filament",   val:"Myosin heads attach to actin → power stroke → sarcomere shortens; ATP needed", col:GOLD },
    { topic:"Smooth Muscle",      val:"No troponin; Ca²⁺ + calmodulin → MLCK → myosin phosphorylation → contraction", col:"2E86C1" },
  ];

  takeaways.forEach((t, i) => {
    const col = i < 4 ? 0 : 1;
    const row = i % 4;
    const x = 0.22 + col * 4.9;
    const y = 0.82 + row * 1.17;
    card(s, x, y, 4.65, 1.05, CARD);
    s.addShape(pres.shapes.RECTANGLE, { x, y, w:0.09, h:1.05, fill:{color:t.col}, line:{color:t.col} });
    s.addText(t.topic, { x:x+0.2, y:y+0.1, w:4.3, h:0.3, fontSize:10.5, bold:true, color:t.col, fontFace:"Calibri", margin:0 });
    s.addText(t.val, { x:x+0.2, y:y+0.44, w:4.3, h:0.52, fontSize:9, color:OFFWHITE, fontFace:"Calibri", margin:0 });
  });
}

// ─── WRITE ────────────────────────────────────────────────────
pres.writeFile({ fileName: "/home/daytona/workspace/nerve-muscle-ppt/Nerve_Muscle_Physiology_BHMS.pptx" })
  .then(() => console.log("✅ Done: Nerve_Muscle_Physiology_BHMS.pptx"))
  .catch(err => { console.error("❌", err); process.exit(1); });

cd /home/daytona/workspace/nerve-muscle-ppt && node create_pptx.js 2>&1