Summary of the topic, methodology of disseminated intravascular coagulation for NEET PG 2026 exam. It is a multiple choice question based exam. It should cover almost 100% of topics that can be asked for disseminated intravascular coagulation.
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This is a comprehensive, exam-ready summary covering all aspects of DIC that are testable in NEET PG 2026. Here's a quick orientation to what's covered:
Structure of the summary:
- Definition — precise, exam-style language
- Etiology — all causes with high-yield exam pearls per category + mnemonic
- Pathophysiology — full cascade (extrinsic/intrinsic triggers → thrombin → consumption → fibrinolysis → FDPs → bleeding), including sepsis-specific molecular mechanism (IL-1/TNF, thrombomodulin)
- Acute vs Chronic DIC — contrasting features (key MCQ target)
- Clinical features — thrombotic + bleeding + MAHA
- Lab findings — complete table with reasons; ISTH scoring system
- Morphology — organs affected, specific syndromes
- Treatment — cause-first principle, FFP vs cryoprecipitate vs platelets vs heparin
- High-yield associations — APL, Trousseau's, Kasabach-Merritt, Waterhouse-Friderichsen, Sheehan's, HELLP
- DIC vs TTP vs HUS — classic differentiator table
- 20 exam-focused high-yield points for last-minute revision
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