You are answering a USMLE-style medical question. Question: A 51-year-old Caucasian woman presents to the physician for a routine health maintenance examination. She had a Colles' fracture 2 years ago. The rest of her past medical history is unremarkable. She has a sedentary lifestyle. She has been smoking 1 pack of cigarettes daily for 30 years. She drinks alcohol moderately. Her mother had a fracture of the wrist when she was in her late 60s. The physical examination shows no abnormal findings. Dual-energy X-ray absorptiometry (DEXA scan) shows a T-score of -3.2 standard deviations (SDs) in the hip. The patient is educated regarding her risk of falls. Exercise regimen and smoking cessation assistance are provided. Appropriate diet is indicated, as well as supplements with calcium and vitamin D. Which of the following is the most appropriate next step in pharmacotherapy? Options: A) Alendronate B) Calcitonin C) Estrogen D) Tamoxifen Reply with ONLY the letter of the correct answer (A, B, C, or D). No explanation.