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Aceclofenac pcm tablet uses

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Aceclofenac Paracetamol tablet uses

Aceclofenac + Paracetamol (PCM) combination tablet - Uses
This is a fixed-dose combination NSAID analgesic, pairing aceclofenac (a non-steroidal anti-inflammatory drug) with paracetamol/acetaminophen (an analgesic-antipyretic). It is commonly marketed for pain, inflammation, and fever relief. Typical clinical uses include:
  • Osteoarthritis - joint pain and stiffness relief
  • Rheumatoid arthritis - pain and inflammation control
  • Ankylosing spondylitis - spinal/joint inflammatory pain
  • Musculoskeletal pain - muscle strains, sprains, backache
  • Post-traumatic/post-operative pain and swelling
  • Toothache and dental pain
  • Headache and throat pain
  • Fever (from the paracetamol component)
  • Dysmenorrhea (menstrual cramps) - sometimes used off-label
How it works
  • Aceclofenac inhibits cyclooxygenase (COX-1/COX-2), reducing prostaglandin synthesis, which lowers inflammation and pain at the site of tissue injury. NSAIDs of this class (aceclofenac, diclofenac, etc.) work through this same mechanism - Maudsley Prescribing Guidelines in Psychiatry, 15ed.
  • Paracetamol acts more centrally, modulating pain signaling and the hypothalamic thermoregulatory center to reduce fever, with a comparatively weak peripheral anti-inflammatory effect.
Together, the combination gives more effective pain and fever control than either drug alone at standard doses, while allowing a somewhat lower NSAID dose to be used.
Important precautions
  • Take after food to reduce gastrointestinal irritation/risk of ulcers.
  • Avoid in active peptic ulcer disease, severe hepatic or renal impairment, and third-trimester pregnancy.
  • Use caution with alcohol (raises risk of GI bleeding and hepatotoxicity), and avoid exceeding the recommended paracetamol dose (hepatotoxicity risk).
  • Not recommended for long-term self-use without medical supervision; caution in patients with cardiovascular disease, asthma/NSAID-sensitivity, or those on anticoagulants.
  • Always follow the dose and duration prescribed by a physician or as printed on the label - this combination is typically available only via prescription in many markets, though OTC in some.
This information is general; if you're asking about a specific brand or dose, or have a particular condition/medication list, let me know and I can tailor the answer (e.g., interactions with your other medications).
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