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Acute STEMI on ECG
Diagnostic Criteria (from Washington Manual & Tintinalli's Emergency Medicine)
ST elevation is measured at the J point in at least 2 anatomically contiguous leads:
| Patient Group | Leads V2-V3 | All Other Leads |
|---|
| Men > 40 years | ≥ 2 mm | ≥ 1 mm |
| Men < 40 years | ≥ 2.5 mm | ≥ 1 mm |
| Women | ≥ 1.5 mm | ≥ 1 mm |
| Posterior leads (V7-V9) | 0.5 mm | - |
| Right-sided leads (V3R, V4R) | 0.5 mm (1 mm if male <30 yrs) | - |
ST Elevation Morphology in STEMI
The ST segment in ischemia classically shows these shapes:
The convex (tombstone) or straight horizontal pattern is most specific for ischemic ST elevation. Measurement is always taken at the J point (junction of QRS end and ST segment beginning):
Real 12-Lead STEMI ECG
This 12-lead ECG shows an anterior STEMI with marked ST elevation in the precordial leads:
Localization by Leads (Tintinalli Table 49-4)
| Territory | Leads with STE | Culprit Vessel |
|---|
| Anteroseptal | V1-V3 | Proximal LAD |
| Anterior | V1-V4 | LAD |
| Anterolateral | V1-V6, I, aVL | Proximal LAD |
| Lateral | I, aVL | Diagonal or LCx |
| Inferior | II, III, aVF | RCA (or LCx) |
| Inferolateral | II, III, aVF, V5-V6 | RCA or LCx |
| Posterior | Tall R in V1-V2 (mirror image) | LCx |
| Right Ventricular | II, III, aVF + V3R-V6R | Proximal RCA |
Other Key ECG Features
Reciprocal ST depression - ST depression in leads opposite the infarct zone (e.g., inferior STE + lateral ST depression). This increases specificity for true MI and signals larger territory at risk with worse prognosis.
Hyperacute T-waves - Tall, broad, peaked T-waves are often the earliest STEMI sign, appearing before ST elevation develops.
Pathologic Q waves - Develop later (hours), indicating transmural necrosis:
- In V2-V3: Q wave ≥ 0.02 sec, or QS complex
- Other leads: Q wave ≥ 0.03 sec and ≥ 0.1 mV deep in ≥ 2 contiguous leads
New LBBB - Suggests large anterior MI; use Sgarbossa criteria to diagnose MI in existing LBBB (concordant STE ≥1 mm, concordant STD ≥1 mm in V1-V3, or discordant STE ≥5 mm).
STEMI Equivalents (Do Not Miss)
- Posterior MI: ST depression V1-V3 + tall R waves - place posterior leads (V7-V9) to confirm
- De Winter T-waves: Upsloping ST depression + tall peaked T-waves in V1-V6 = proximal LAD occlusion
- Wellens syndrome: Biphasic or deeply inverted T-waves in V2-V3 = critical LAD stenosis (post-pain ECG)
- aVR elevation: STE in aVR with diffuse ST depression = left main or proximal LAD occlusion
Differential Diagnosis of ST Elevation (NOT STEMI)
Per the Washington Manual, conditions mimicking STEMI include:
| Cardiac | Non-Cardiac |
|---|
| Prior MI with aneurysm | Pulmonary embolism |
| Pericarditis | Hyperkalemia |
| Myocarditis | Early repolarization (normal) |
| Aortic dissection | - |
| Brugada syndrome | - |
| Coronary vasospasm (Prinzmetal) | - |
Key tip: Always compare to a prior ECG. Obtaining old ECGs is essential to determine whether changes are new or chronic.
- Washington Manual of Medical Therapeutics, pp. 147-148
- Tintinalli's Emergency Medicine, Table 49-4