Refer Harrison textbook of medicine or standard textbook

Reading File

Asking for Preferences

Finding Sources

Reading File

Finding Sources

Reading File

Loading Image

All 7 learning objectives are now covered. Here's a quick orientation to the full answer above:

What Was Covered

Objective	Topic	Key Points
GM 7.10	Differential Diagnosis	Mono vs. poly, inflammatory vs. non-inflammatory, pattern recognition, associated features
GM 7.11	Diagnostic Workup	CBC, RF, anti-CCP, ANA, anti-dsDNA, anti-Smith, complement, uric acid - when to order and how to interpret
GM 7.12	Arthrocentesis	Indications (4 main), contraindications, synovial fluid analysis table, crystal types, algorithm (with image)
GM 7.13	Plain Radiographs	Disease-specific X-ray findings for RA, OA, gout, pseudogout, AS, psoriatic arthritis (with gout X-ray image)
GM 7.15/7.17	Treatment Plans	RA (NSAIDs → DMARDs → biologics → JAK inhibitors), SLE, AS, OA - stepwise protocols
GM 7.16	Crystalline Arthropathies	Gout acute treatment (NSAIDs, colchicine, steroids) + prophylaxis (allopurinol, probenecid, febuxostat); pseudogout management

High-yield points to remember:

Anti-CCP is more specific than RF for RA; anti-dsDNA is specific for SLE and tracks disease activity
Gout crystal = negatively birefringent, needle-shaped; pseudogout = positively birefringent, rhomboid
Never start allopurinol during an acute gout attack; cover with colchicine for 3-6 months
Synovial WBC >50,000 = presumptive septic arthritis until proven otherwise
Chondrocalcinosis on X-ray = pseudogout (CPPD); punched-out erosions = chronic gout

This is a shared conversation. Sign in to Orris to start your own chat.