propranolol patient information common serious side effects NHS
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propranolol adverse effects
The medicine shown is Hypernol-20: propranolol hydrochloride 20 mg, a beta-blocker.
Common side effects
Tiredness, weakness, dizziness or light-headedness
Cold hands and feet
Sleep problems, vivid dreams or nightmares
Nausea, diarrhoea or constipation
Headache
Slower heart rate
Low blood pressure, which may cause faintness when standing
These often improve after the body adjusts. The NHS propranolol guidance lists dizziness, tiredness, cold extremities, sleep difficulty and nightmares among the usual effects.
Seek urgent medical help now for:
Wheezing, shortness of breath, chest tightness, or an asthma attack
Fainting, severe dizziness, confusion
Very slow or irregular heartbeat
Swelling of lips/tongue, hives, blistering rash, or trouble breathing
Chest pain
Important cautions
Propranolol can worsen asthma/COPD because it can cause bronchoconstriction. It is generally avoided in bronchial asthma.
In diabetes, it can mask warning signs of low blood sugar, particularly a fast heartbeat.
Avoid alcohol initially because it can add to dizziness and low blood pressure.
Do not stop it suddenly without the prescriber’s advice, particularly if taken regularly for a heart condition or blood pressure.
If you are having a side effect now, tell me what symptom you have, when you took the tablet, and whether you have asthma, diabetes, low blood pressure, or heart disease.
Side effects
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propranolol adverse effects
For Hypernol-20 (propranolol 20 mg):
Common side effects
Tiredness or weakness
Dizziness, especially when standing up
Cold hands or feet
Headache
Nausea, vomiting, diarrhoea, or constipation
Sleep disturbance, vivid dreams, or nightmares
Slow heart rate or low blood pressure
Reduced sexual performance in some people
Serious side effects - seek urgent care
Wheezing, chest tightness, or difficulty breathing, especially if you have asthma
Fainting, severe dizziness, very slow pulse, or irregular heartbeat
New/worsening shortness of breath or swelling of legs
Severe low blood sugar symptoms, especially in people with diabetes. Propranolol may hide the usual warning sign of a fast heartbeat.
Face/lip/tongue swelling, widespread itchy rash, or trouble breathing, which may indicate allergy
Chest pain
Avoid suddenly stopping propranolol unless a clinician tells you to. It can lead to rebound fast heartbeat, raised blood pressure, or chest pain. Propranolol can cause bronchospasm and can slow heart rate or worsen heart block, as described in Morgan and Mikhail’s Clinical Anesthesiology. The NHS side-effect page has additional patient guidance.
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