Perinorm = metoclopramide. For pediatric perioperative nausea/vomiting, the dose commonly cited in anesthesia references is:

Example: a 20-kg child at 0.1 mg/kg receives 2 mg IV.

However, metoclopramide is not a preferred routine antiemetic in children because of acute dystonia, akathisia, and other extrapyramidal reactions. It should be avoided in infants, especially neonates, and used only under clinician/anesthesia supervision. Current product labeling states that pediatric safety and effectiveness are not established for most indications, apart from facilitating small-bowel intubation, and highlights pediatric susceptibility to adverse effects (DailyMed labeling).

For pediatric PONV, ondansetron plus dexamethasone is generally favored over metoclopramide. A 2025 pediatric systematic review also compared these drugs in adenotonsillectomy patients (PMID: 39992376).