Respiratory panel for bacteria viral fungus test names
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Here is a comprehensive overview of the Respiratory Pathogen Panel (RPP) - the test names and what each category covers:
Respiratory Pathogen Panel (RPP)
Other names for this test:
- RP Panel / Respiratory Panel (RP)
- Respiratory Virus Profile
- Multiplex Respiratory Panel
- Multi-pathogen Molecular Assay
- Syndromic Multiplex PCR Panel
- Respiratory Pathogen Multiplex RT-PCR
Method: Multiplex PCR / RT-PCR on nasopharyngeal swab, oropharyngeal swab, or lower respiratory specimen (BAL, sputum)
VIRAL Targets
| # | Pathogen |
|---|---|
| 1 | Influenza A (including H1N1, H3N2 subtypes) |
| 2 | Influenza B |
| 3 | Influenza C |
| 4 | Respiratory Syncytial Virus (RSV) A & B |
| 5 | Human Metapneumovirus (hMPV) A & B |
| 6 | Parainfluenza Virus type 1 |
| 7 | Parainfluenza Virus type 2 |
| 8 | Parainfluenza Virus type 3 |
| 9 | Parainfluenza Virus type 4 |
| 10 | Adenovirus |
| 11 | Rhinovirus / Enterovirus |
| 12 | Coronavirus 229E |
| 13 | Coronavirus OC43 |
| 14 | Coronavirus NL63 |
| 15 | Coronavirus HKU-1 |
| 16 | SARS-CoV-2 (COVID-19) |
| 17 | Human Bocavirus |
| 18 | Human Parechovirus |
BACTERIAL Targets
| # | Pathogen |
|---|---|
| 1 | Streptococcus pneumoniae |
| 2 | Mycoplasma pneumoniae |
| 3 | Chlamydophila (Chlamydia) pneumoniae |
| 4 | Haemophilus influenzae |
| 5 | Moraxella catarrhalis |
| 6 | Staphylococcus aureus (including MRSA) |
| 7 | Klebsiella pneumoniae |
| 8 | Pseudomonas aeruginosa |
| 9 | Legionella pneumophila |
| 10 | Bordetella pertussis (whooping cough) |
| 11 | Bordetella parapertussis |
| 12 | Acinetobacter baumannii |
| 13 | Streptococcus pyogenes (Group A Strep) |
| 14 | Streptococcus agalactiae (Group B Strep) |
Extended panels may also include antimicrobial resistance genes (e.g., mecA for MRSA, beta-lactamase genes)
FUNGAL Targets
| # | Pathogen |
|---|---|
| 1 | Pneumocystis jirovecii (PCP - most consistently included) |
| 2 | Aspergillus species |
| 3 | Candida species |
| 4 | Cryptococcus neoformans/gattii |
| 5 | Histoplasma capsulatum |
| 6 | Coccidioides species |
| 7 | Blastomyces dermatitidis |
| 8 | Fusarium species |
| 9 | Mucor/Rhizopus species (Mucormycetes) |
Note: Fungal targets vary significantly between panels. Most standard upper respiratory panels include only Pneumocystis jirovecii. Extended/lower respiratory or immunocompromised-patient panels include the broader fungal list above.
Common Commercial Panels by Manufacturer
| Panel Name | Manufacturer | Targets |
|---|---|---|
| BioFire FilmArray RP2.1 | BioFire/bioMerieux | ~22 targets (viral + bacterial) |
| QIAstat-Dx Respiratory Panel | QIAGEN | 21 targets |
| NxTAG Respiratory Pathogen Panel | Luminex | 20 targets |
| ePlex Respiratory Pathogen Panel | GenMark Dx | 22 targets |
| Verigene Respiratory Flex | Luminex/Nanosphere | viral + bacterial |
| MedGenome Respiratory Multiplex | MedGenome | 17 bacteria + 17 viruses + P. jirovecii |
Sample Types
- Upper respiratory: Nasopharyngeal (NP) swab, oropharyngeal swab, nasal wash
- Lower respiratory: Bronchoalveolar lavage (BAL), sputum, tracheal aspirate
Key Notes
- Most panels are qualitative (detected / not detected)
- Turnaround time: 1-5 hours for in-lab platforms; point-of-care panels can return results in ~45-75 minutes
- Fungal testing is less standardized - severe/immunocompromised cases often require separate dedicated fungal workup (galactomannan, beta-D-glucan, culture)
- The panel does not replace culture for antimicrobial susceptibility testing
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