When do treat donovo DSA without histological ABMR in renal transplantation

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De novo donor-specific antibodies (dnDSA) without histological ABMR is a recognized clinical dilemma - treatment is generally indicated when there are risk factors for progression (high MFI, complement-fixing C1q/C3d-binding, rising DSA, functional decline), but observation may be appropriate in low-risk cases.
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de novo donor specific antibody renal transplant treatment without ABMR

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de novo DSA kidney transplant subclinical treatment

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dnDSA kidney transplant management ABMR histology

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"de novo donor-specific antibodies" kidney transplant treatment subclinical

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PMID: 37169835

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