Test me on genetial formation

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I now have comprehensive textbook content covering all major aspects of genital formation. Let me build your MCQ quiz.

Genital Formation - MCQ Quiz

Here are 10 multiple-choice questions covering the full overview. Answer each one and I'll give you detailed feedback afterward!

Question 1 - The Indifferent Stage

During the indifferent stage of genital development, which of the following is TRUE?

A) The female fetus lacks Wolffian ducts
B) The male fetus lacks Mullerian ducts
C) Both sexes have both Wolffian (mesonephric) and Mullerian (paramesonephric) ducts
D) Genetic sex is not yet determined at this stage

Question 2 - Gonad Formation Timing

Primordial germ cells migrate from the yolk sac to the genital ridges during which weeks of gestation?

A) Weeks 1-3
B) Weeks 4-6
C) Weeks 8-10
D) Weeks 12-14

Question 3 - SRY Gene

The SRY gene is located on which chromosome and produces which factor?

A) X chromosome; estrogen-stimulating factor
B) Y chromosome (short arm); testis-determining factor (TDF)
C) Chromosome 17; SOX9 activator protein
D) Y chromosome (long arm); Müllerian-inhibiting factor (MIF)

Question 4 - Male Gonad Development

Expression of the SRY gene results in all of the following EXCEPT:

A) Development of medullary (testis) cords
B) Formation of the tunica albuginea
C) Formation of cortical (ovarian) cords
D) Differentiation of Sertoli and Leydig cells

Question 5 - Female Gonad Development

Which gene is considered the master regulator of ovarian development?

A) SRY
B) SOX9
C) WNT4
D) SF1 (steroidogenic factor-1)

Question 6 - Male Internal Duct Development

In the male, the Wolffian duct is preserved and differentiates into which structures?

A) Fallopian tubes, uterus, upper vagina
B) Ductus deferens, epididymis, seminal vesicles, ejaculatory duct
C) Prostate only
D) Urogenital sinus and bladder

Question 7 - Müllerian Regression

Which hormone causes regression of the Müllerian ducts in the male embryo, and which cells produce it?

A) Testosterone, produced by Leydig cells
B) DHT, produced by Sertoli cells
C) Anti-Müllerian hormone (AMH), produced by Sertoli cells
D) Estrogen, produced by granulosa cells

Question 8 - Female Internal Duct Development

In the female, the fused Müllerian ducts give rise to which of the following?

A) Ductus deferens and seminal vesicles
B) Fallopian tubes, uterus, cervix, and upper one-third of the vagina
C) Clitoris and labia majora
D) Ovaries and the broad ligament

Question 9 - External Genitalia: Male

The influence of DHT on androgen receptors during weeks 9-13 causes the genital tubercle, genital folds, and genital swellings to develop into what male structures, respectively?

A) Glans penis, penile shaft, scrotum
B) Penile shaft, scrotum, glans penis
C) Scrotum, glans penis, penile shaft
D) Prostate, glans penis, scrotal raphe

Question 10 - Default Pathway

Which of the following best describes the "default" developmental pathway for external genitalia?

A) Male development occurs without any hormonal input
B) Female development requires estrogen to proceed
C) Without DHT (regardless of genetic or gonadal sex), external genitalia develop along the female template
D) Both male and female pathways require equal hormonal input

Reply with your answers (e.g., "1-C, 2-B, 3-A...") and I'll give you full explanations for each one!

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