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TUBERCULOSIS OF HIP JOINT

DEFINITION & INCIDENCE

  • 2nd most common site of osteoarticular TB after spine
  • 15-20% of all osteoarticular TB cases
  • Predominantly affects children; concurrent/prior pulmonary TB in ~50%

PATHOLOGY

Sites of initial focus (in order):
  1. Acetabular roof (most common)
  2. Femoral epiphysis
  3. Proximal femoral metaphysis
  4. Greater trochanter
  5. Rarely - synovial membrane
Sequence: Bone focus → granulation tissue → caseation → spreads to cartilage, synovium, capsule → cold abscess → perforation of capsule → sinus/intrapelvic abscess
Head and neck of femur are intracapsular → bony lesion here invades joint early; acetabular lesion invades joint late

CLINICAL FEATURES - THREE STAGES

FeatureStage I: SynovitisStage II: Early ArthritisStage III: Advanced Arthritis
DeformityFlexion + Abduction + ERFlexion + Adduction + IRFlexion + Adduction + IR (severe)
Limb LengthApparent lengtheningApparent shortening (true ≤1 cm)True shortening
CapsuleDistended by effusionFibrotic, contractingDestroyed
JointMax capacity positionDamaged articular surfacePathological dislocation
Common symptoms (all stages):
  • Pain in hip/thigh or referred to medial knee
  • Limp, avoidance of weight bearing
  • Night cries (muscle spasm relaxes during sleep)
  • Muscle atrophy, restricted movements

RADIOLOGICAL CLASSIFICATION (7 Types - Bhan & Nag)

TypeFeaturePrognosis
NormalMainly synovial; joint space preservedGood
Perthes'Sclerotic femoral head; children <5 yrsGood
DislocatingSubluxation/dislocation; capsular laxityGood (open relocation)
Wandering acetabulumSubchondral bone erosionPoor
Protrusio acetabuliMedial acetabular wall destroyedPoor
Mortar & PestleErosion of subchondral bonePoor
AtrophicIrregular femoral head; narrow joint space; adults onlyVery poor → fibrous ankylosis
  • Normal/Perthes'/Dislocating → symptom duration 4-7 months
  • Wandering/Protrusio/Mortar & Pestle → duration 10-14 months

INVESTIGATIONS

TestFinding
X-rayOsteopenia → osteolytic focus → joint destruction
USGEarly soft tissue swelling, effusion
MRIBest early imaging; 100% sensitivity, 88% specificity
Synovial fluidThick; high protein; lymphocytic; culture positive in most
Synovial biopsyCaseating granuloma + Langhans giant cells - gold standard
CBNAAT (Xpert MTB/RIF)Sensitivity 94.6%, specificity 85.3% in bone/joint tissue

DIFFERENTIAL DIAGNOSIS

  • Perthes' disease
  • Septic arthritis
  • Transient synovitis
  • Rheumatoid arthritis
  • CDH (Congenital Dislocation of Hip)
  • Osteoarthritis

MANAGEMENT

1. Anti-TB Treatment

  • 2HRZE / 10-16HRE (total 12-18 months; many orthopaedicians prefer 18-24 months)
  • DOTS compliance mandatory

2. Skin Traction (all stages initially)

  • Corrects deformity, relieves spasm, maintains joint space, prevents dislocation
  • Abduction deformity → traction to both limbs
  • Stages I & II: up to 12 weeks traction

3. Weight-Bearing Protocol

12 weeks traction → 12 weeks NWB with crutches → 12 weeks partial WB → unprotected WB

4. Surgery

Stage/ConditionProcedure
Stage IIPartial synovectomy + curettage of osteolytic lesions ± cancellous bone graft
Stage IIISynovectomy + debridement → plaster spica 6-9 months → aim: fibrous ankylosis in functional position
Ankylosis in bad positionCorrective femoral osteotomy (above lesser trochanter)
After age 20, ankylosis neededArthrodesis - Hibb's (iliofemoral) or Britain's (ischiofemoral)
Painful hip, preserve ROMExcision arthroplasty (Girdlestone) - excise head & neck; limb 2 cm short but patient can squat
Healed >5 years / selected active casesTotal Hip Arthroplasty (THA)

5. Cold Abscess

  • Drain promptly to prevent sinus formation

COMPLICATIONS

  • Pathological dislocation
  • Wandering acetabulum
  • Cold abscess & sinuses
  • Limb shortening (bone destruction + growth arrest)
  • Secondary pyogenic infection
  • Fibrous ankylosis in deformity

RAPID RECALL (Memory Aid)

  • Stage I = FAb+ER (like resting position) → apparent long
  • Stage II = FAd+IR (like antalgic guard) → apparent short
  • Stage III = same + true shortening + dislocation
  • MRI = best early imaging
  • Biopsy = gold standard
  • CBNAAT = rapid molecular diagnosis

Source: Sharma & Mohan, Textbook of TB, 3rd Ed., Chapter 19 (Bhan & Nag); Harrison's 22e
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