50 mark university post graduate theory exam , Question : microbial interactions with the host in periodontal disease. Prepare answer using the uploaded reference , provide long form of abbrevation used
| Section | Marks Weightage |
|---|---|
| I. Introduction + Microbial Virulence Factors (MAMPs, LPS, proteases) | ~5 |
| II. Innate Immune Response - JE, Neutrophils, Complement, Chemotaxis | ~12 |
| III. PRRs in Detail - TLRs (TLR2, TLR4, TLR9), NLRs, NLRP3 inflammasome, Signaling pathways (MyD88, TRIF) | ~12 |
| IV. Adaptive Immune Response - APC, TCR signaling, Th1/Th2/Th17/Treg cells, B-cells, Humoral immunity | ~10 |
| V. ROS, Neuropeptides (Substance P, VIP) | ~3 |
| VI. Keystone Pathogen Concept - PSD model, P. gingivalis guerilla tactics, Genetic dysbiosis | ~5 |
| VII. Models of Disease Progression (Kornman, Offenbacher) | ~3 |
| VIII-X. Risk factors, Integrated pathogenesis, Omic sciences | ~5 |
| Complete Abbreviation Glossary (90+ expansions) | Included |