The bottle shown contains
codeine phosphate 10 mg + triprolidine 1.25 mg per 5 mL.
Do not start or self-dose this syrup at 7 weeks of pregnancy unless your obstetrician or treating doctor specifically prescribes it. Codeine can cause drowsiness and suppress breathing, and first-trimester safety data are not fully certain. A 2024 review found no major overall increase in birth defects with opioid exposure, but the evidence has limitations and a small association with atrial septal defects after codeine exposure was reported (
review, PMID 38715235). The UK pregnancy medicines service likewise advises codeine only when recommended by a doctor (
BUMPS guidance).
Because the cough is uncontrollable despite Budecort, please arrange an in-person assessment today, ideally with your obstetrician or a physician. Budecort (budesonide) is a controller inhaler for airway inflammation, not an immediate cough suppressant. Persistent cough can be from asthma flare, viral infection, pneumonia, reflux, postnasal drip, or another cause. In pregnancy, an atypical respiratory picture or lack of response to therapy warrants assessment, including oxygen level and chest examination. Do not stop a prescribed asthma controller without medical advice.
Go to emergency care now if there is any shortness of breath, wheezing or chest tightness, trouble speaking full sentences, blue lips, chest pain, coughing blood, high fever, confusion/fainting, oxygen saturation below 95% if you can measure it, or you are needing a rescue inhaler repeatedly.
Until reviewed:
- Use only the inhalers exactly as already prescribed. If you have a prescribed rescue inhaler such as salbutamol, follow your asthma action plan or contact the prescriber urgently for instructions.
- Fluids, warm drinks, honey with lemon if suitable for you, humidified air, and avoiding smoke/perfume/dust may help.
- Avoid mixing cough syrups, alcohol, sleeping tablets, antihistamines, or sedatives with codeine.
- Do not take antibiotics unless prescribed after assessment. Most acute coughs are viral, and codeine cough medicines may not stop the cough (NHS cough guidance).
The cough itself usually does not harm the pregnancy, but poorly controlled asthma or low oxygen must be treated promptly.