Here is a thorough, textbook-grounded breakdown of the 10 most common ECG diagnoses and findings:
10 Most Common ECG Diagnoses and Findings
1. Normal Sinus Rhythm (Baseline Reference)
Before recognizing pathology, every ECG is assessed against normal:
- Rate: 60-100 bpm
- P wave: upright in leads I and II, precedes every QRS
- PR interval: 120-200 ms
- QRS: <120 ms, axis -30° to +90°
- QT interval: <450 ms (men), <470 ms (women)
2. Sinus Tachycardia
- Rate: >100 bpm with a normal P-QRS-T sequence
- P waves are upright and precede each QRS (1:1 relationship)
- Most common dysrhythmia seen on ECG overall - present in ~40% of emergency patients with acute illness (e.g. PE, thyrotoxicosis, sepsis)
- Not a primary arrhythmia - always look for the underlying cause
3. Atrial Fibrillation (AF)
One of the most clinically important and frequently encountered diagnoses:
- Absent P waves - replaced by irregular, chaotic fibrillatory (f) waves, best seen in V1
- Irregularly irregular ventricular response (RR intervals vary with no pattern)
- Narrow QRS unless aberrant conduction or bundle branch block co-exists
- When AF is associated with pulmonary hypertension, the ECG may show: R/S ratio in V1 >1, right axis deviation, and ST depressions in V1-V3 (Tintinalli's Emergency Medicine)
- Common in mitral stenosis: ECG shows AF, left atrial enlargement, or right axis deviation
4. Left Ventricular Hypertrophy (LVH)
The most common ECG finding in hypertensive patients and dilated cardiomyopathy:
- Voltage criteria - Several exist; all have poor sensitivity (30-50%) but good specificity (85-95%)
- Cornell criterion: S in V3 + R in aVL >28 mm (men) or >20 mm (women)
- Sokolow-Lyon: S in V1 + R in V5 or V6 >35 mm
- Associated with ST depression and T wave inversion in lateral leads ("strain pattern")
- LV hypertrophy + left atrial enlargement are the most common findings in dilated cardiomyopathy (Tintinalli's)
5. Right Bundle Branch Block (RBBB)
ECG hallmarks (from Goldman-Cecil and Braunwald's):
- QRS duration ≥120 ms
- rsR' pattern ("M-shape") in V1 - the classic finding
- Wide, slurred terminal S wave in leads I, V5, V6
- ST-segment downsloping and T wave inversion in right precordial leads (V1-V3) - discordant with QRS
- Normal axis; septal Q waves present in lateral leads
- Can be isolated or combined with left anterior fascicular block (bifascicular block)
RBBB - note the rSR' in V1 and wide terminal S wave in V5 (Goldman-Cecil Medicine)
6. Left Bundle Branch Block (LBBB)
ECG hallmarks:
- QRS duration ≥120 ms
- Broad, notched (M-shaped) complex in I, aVL, and left precordial leads (V5-V6)
- Small r waves and broad, deep S waves in right precordial leads (V1-V3)
- ST and T waves discordant (opposite to) the QRS throughout the precordium
- Axis usually normal or deviated left
- New LBBB in a patient with chest pain is treated as a STEMI equivalent
D: Left posterior fascicular block (right axis deviation ~120°). E: LBBB - broad notched R waves in lateral leads, deep S in right precordial leads (Goldman-Cecil Medicine)
7. ST-Elevation Myocardial Infarction (STEMI)
The highest-stakes ECG diagnosis:
- ST elevation ≥1 mm in ≥2 contiguous limb leads, or ≥2 mm in ≥2 contiguous precordial leads
- Reciprocal ST depression in opposite leads
- Hyperacute T waves - earliest finding (tall, broad, asymmetric)
- Pathological Q waves - develop within hours to days (>40 ms wide or >25% of R wave height)
- Localizing territory:
- Inferior (II, III, aVF) = RCA occlusion
- Anterior (V1-V4) = LAD occlusion
- Lateral (I, aVL, V5-V6) = LCx occlusion
- STEMI management target: door-to-balloon <90 min; primary PCI preferred over thrombolysis (Textbook of Family Medicine)
- New LBBB or posterior STEMI (ST depression V1-V3 with tall R waves) are STEMI equivalents
8. Non-Specific ST-T Wave Changes
The most common "abnormal" finding on routine ECGs:
- ST depression or T wave inversion that does not meet ischemia criteria
- T wave flattening or subtle inversion
- Causes are extensive: ischemia, LVH strain, electrolyte disturbance (hypokalemia), digoxin effect, myocarditis, pericarditis, cardiomyopathy
- Must always be interpreted in clinical context
- Sinus tachycardia + nonspecific ST-T changes are the most common ECG findings in pulmonary embolism - they do NOT confirm or exclude the diagnosis
9. First-Degree AV Block (and Fascicular Blocks)
First-degree AV block:
- PR interval >200 ms (>5 small squares)
- Every P wave conducts to a QRS - no beats dropped
- Often benign; seen in athletes, with inferior MI, or drug effect (beta-blockers, digoxin)
Fascicular blocks are also very common:
- Left anterior fascicular block (LAFB): Left axis deviation (around -60°), normal QRS duration, small Q waves in I/aVL, small R waves in II/III/aVF
- Left posterior fascicular block (LPFB): Right axis deviation (~+120°), delayed R-wave progression, requires exclusion of other causes of right axis deviation
10. Ventricular / Atrial Premature Beats
- Premature Ventricular Complexes (PVCs): Wide, bizarre QRS (>120 ms), no preceding P wave, full compensatory pause. Very common - seen in up to 30% of monitored patients. Usually benign in isolation but complex forms (couplets, bigeminy, multifocal) warrant evaluation
- Premature Atrial Complexes (PACs): Early, narrow QRS preceded by an abnormal P wave; often conducted with a slight PR change or blocked entirely
- Both are documented in ECG recording tables from Braunwald's Heart Disease and Goldman-Cecil as top findings in long-term Holter monitoring
Summary Table
| # | Diagnosis | Key ECG Feature |
|---|
| 1 | Normal sinus rhythm | Rate 60-100, regular P-QRS-T |
| 2 | Sinus tachycardia | Rate >100, normal morphology |
| 3 | Atrial fibrillation | No P waves, irregularly irregular RR |
| 4 | LVH | Increased voltage ± strain pattern |
| 5 | RBBB | rSR' in V1, wide S in I/V5/V6 |
| 6 | LBBB | Broad notched R in I/aVL/V6, deep S in V1 |
| 7 | STEMI | ST elevation ≥1-2 mm in contiguous leads |
| 8 | Nonspecific ST-T changes | ST depression/T inversion, nondiagnostic |
| 9 | First-degree AV block / fascicular blocks | PR >200 ms / axis deviation |
| 10 | PVCs / PACs | Wide bizarre QRS / early narrow QRS |
Sources: Goldman-Cecil Medicine, Braunwald's Heart Disease, Tintinalli's Emergency Medicine, Textbook of Family Medicine - all via the medical textbook library.