THR PROTOCOL

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I now have comprehensive data from multiple authoritative sources. Let me compile the complete THR protocol answer.

Total Hip Replacement (THR) Protocol

A comprehensive protocol for Total Hip Replacement (THR / Total Hip Arthroplasty, THA) covering indications, implant selection, surgical approach, perioperative management, and complications.

1. Indications

THR is indicated when hip pathology causes significant pain and functional disability that has failed conservative management. Common indications include:
  • Osteoarthritis (primary and secondary) - the most frequent indication
  • Rheumatoid/inflammatory arthritis
  • Avascular necrosis (AVN) of the femoral head
  • Displaced femoral neck fractures (in the elderly or physiologically frail)
  • Post-traumatic arthritis
  • Dysplastic hip disease
  • Ankylosing spondylitis
  • Failed previous hip procedures (e.g., hemiarthroplasty, internal fixation)
Over 95,000 primary THRs are performed annually in the UK alone. With evidence-based technique and prosthesis selection, over 95% of patients have a well-functioning THR at 10 years, and 85% remain functional at 20 years - [Bailey and Love's Short Practice of Surgery, 28th Ed](p. 581).

2. Components and Design Principles

An ideal joint replacement must be:
  • Biocompatible and inert
  • Well fixed to host tissue
  • Allow good range of movement and stability
  • Minimize wear particles (to prevent osteolysis)
  • Release non-toxic materials
  • Remove the minimum amount of bone (to allow future revision)
  • Cost-effective and ideally outlive the patient
(Bailey and Love, 28th Ed, Summary Box 39.5)

Femoral Component Materials

Cobalt-chrome alloy, stainless steel, or titanium. Metal implants tolerate high loads and are relatively inert. Titanium is preferred for cementless stems; cobalt-chrome for cemented designs.

Bearing Surfaces (Table 39.6 - Bailey and Love)

Bearing TypeAdvantagesDisadvantagesBest For
Metal-on-polyethyleneProven; cheapHigh wear; osteolysis riskAge >70 years
Ceramic-on-polyethyleneLower wear rateExpensive; fracture riskAge <70 years (UHMWPE preferred)
Metal-on-metalLow wear rateMetal ion release; ARMD; recallsSelect young males only (head >48 mm)
Ceramic-on-ceramicLowest wear rate (delta ceramics)Expensive; squeaking; fracture riskHigh-functioning young patients
UHMWPE = ultra-high-molecular-weight polyethylene. Highly cross-linked PE stays below the osteolytic threshold even with large heads (≥36 mm). - [Miller's Review of Orthopaedics, 9th Ed](p. 11653)

3. Fixation Method

MethodComponentAdvantagesDisadvantages
CementedFemurProven results; works in osteoporotic/poor bone; lower periprosthetic fracture rateExothermic reaction; cement fragments cause wear; difficult to revise
CementedAcetabulumCheap; useful in osteoporotic boneHigher shear forces; earlier failure
CementlessFemurNo cement; biological/dynamic fixationPerfect fit required; risk of intraop fracture; expensive
CementlessAcetabulumGold standard; can be augmented with screwsImproper technique risks acetabular fracture
Key principles for cementless fixation:
  • Requires: live host bone + appropriate ingrowth surface + initial rigid fixation
  • Hydroxyapatite coating shortens time to biologic fixation
  • Motion within bone leads to fibrous encapsulation instead of osseointegration
  • Femoral stress shielding results from modulus mismatch between stem and femoral bone
Current preference: Cementless fixation is preferred for the acetabular component. Cemented fixation is preferred for the femoral component in patients with poor bone quality or femoral neck fractures. - [Miller's Review of Orthopaedics, 9th Ed](p. 11613-11614)

4. Surgical Approaches

(Table 39.8 - Bailey and Love; Schwartz's Principles of Surgery, 11th Ed)
ApproachAnatomical IntervalKey Notes
Posterior (Kocher-Langenbach)Along gluteus maximus fibres; short external rotators dividedMost common; higher dislocation rate unless posterior capsule repaired (0.5% with soft tissue repair)
Anterolateral / HardingeParts of gluteus medius and minimus reflected off greater trochanterGood stability; risk of abductor weakness (Trendelenburg)
Anterior (Smith-Petersen / DAA)Between sartorius/TFL (superficially) and rectus femoris/gluteus medius (deep); truly internervousSupine positioning; fluoroscopy use; 1 week earlier ambulation; BUT higher femoral fracture/loosening rate and wound complications
Trochanteric osteotomyGreater trochanter osteotomizedExtended access; rarely used as primary approach; still useful in revision
Note: No clear difference in patient outcomes between approaches overall. The direct anterior approach carries a higher rate of femoral complications (fracture, loosening); the posterior approach carries higher dislocation risk. - [Miller's Review of Orthopaedics, 9th Ed](p. 11609)

5. Perioperative Protocol

Preoperative

  • Patient optimization (medical comorbidities, BMI, nutritional status)
  • Blood management: patient blood management programs including erythropoietin and intraoperative blood salvage, especially for elective THR
  • Antibiotic prophylaxis planning (e.g., cefazolin within 60 min of incision)
  • Templating: restore correct offset, center of rotation, and leg length

Intraoperative

  • Antibiotic prophylaxis: perioperative antibiotics are a key part of infection prevention, alongside strict aseptic technique in theatre - [Bailey and Love, 28th Ed](p. 581)
  • Reproduce patient's anatomy: correct offset, center of rotation, component orientation, leg length restoration
  • Intraoperative radiographs/fluoroscopy (especially with anterior approach) to verify implant position

Postoperative

  • Hospital stay: typically 2-3 days; day-case THR is performed in select centers
  • Physiotherapy: early mobilization to avoid dislocation-prone movements, especially for the first 6 weeks
  • Occupational therapy: home assessment prior to discharge; raised toilet seat, grab rails, etc.
  • Radiographs: mandatory post-op to confirm implant alignment/orientation and exclude iatrogenic fracture
  • Follow-up: outpatient review at 6 weeks and 1 year post-surgery

6. VTE Prophylaxis

DVT is relatively common after THR if no precautions are taken; PE can be fatal. Prevention protocol includes:
  • Adequate hydration
  • Regional anaesthesia (reduces VTE risk vs. general anaesthesia)
  • Early mobilization
  • Mechanical devices: TED stockings, foot pumps, intermittent pneumatic calf compression
  • Chemical thromboprophylaxis (continued for 4-6 weeks post-op):
    • Low-molecular-weight heparin (LMWH)
    • Warfarin
    • Direct oral anticoagulants (DOACs - e.g., rivaroxaban, apixaban)
(Follow local/national guidelines for specific agents and duration) - [Bailey and Love, 28th Ed](p. 581)

7. Complications

(Table 39.9 - Bailey and Love, 28th Ed; Schwartz's Principles of Surgery, 11th Ed)

Intraoperative

  • Nerve injury (sciatic, femoral, obturator nerves; most commonly deep peroneal nerve - foot drop)
  • Vascular injury (femoral vein/artery)
  • Femoral or acetabular fracture
  • Cement fragments left in joint

Postoperative

ComplicationNotes
InfectionEarly = haematogenous; late = low-grade (S. epidermidis within biofilm); thorough assessment needed
DVT/PECommon without prophylaxis; potentially fatal
DislocationMost common after posterior approach; due to malpositioned components, noncompliance, neuromuscular issues
Leg length discrepancyUnique to THR; prevented by careful templating
Heterotopic ossificationEctopic bone formation around implant
Aseptic/Septic looseningAseptic: particle-induced osteolysis via macrophage RANKL-mediated bone resorption; start-up pain = most common initial presentation
OsteolysisPE wear particles phagocytized by macrophages → RANKL → osteoclast activation
Implant fracture/failureFemoral stem: cantilever bending; requires revision
Iliopsoas impingement/tendonitisUnique to THR
Stress shieldingProximal bone loss from modulus mismatch

Dislocation Management

  • Closed reduction under conscious sedation (traction/manipulation) - usually successful
  • Recurrent dislocation + malpositioned components → component revision
  • Recurrent dislocation + well-positioned components → larger femoral head, dual-mobility construct, or constrained THA - [Schwartz's, 11th Ed](p. 519)

8. Revision THR Indications

Revision is required for:
  • Symptomatic implant loosening (aseptic or septic)
  • Recurrent dislocations
  • Periprosthetic fracture
  • Femoral prosthesis fracture
  • Significant osteolysis/polyethylene wear
Most femoral revisions use cementless, diaphysis-engaging implants (tapered fluted modular titanium stems). Acetabular revision with porous hemispheric cup + multiple screws handles the majority of cases. Severe bone loss may require modular metal constructs, cup-cage constructs, or custom triflange cups. - [Miller's Review of Orthopaedics, 9th Ed](p. 11630-11640)

Sources:
  • Bailey and Love's Short Practice of Surgery, 28th Ed, Ch. 39 (pp. 580-582)
  • Schwartz's Principles of Surgery, 11th Ed, Ch. 43 (pp. 1934-1938)
  • Miller's Review of Orthopaedics, 9th Ed, Section 5-7 (pp. 11608-11660)
  • Campbell's Operative Orthopaedics, 15th Ed 2026
  • Rockwood and Green's Fractures in Adults, 10th Ed 2025

Physiotherapy

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Excellent - I now have very detailed, authoritative content from Campbell's Operative Orthopaedics 15th Ed on postoperative management/physiotherapy for THR. Let me compile the full answer.

Physiotherapy After Total Hip Replacement (THR)

Here is the complete physiotherapy and rehabilitation protocol following THR, based on Campbell's Operative Orthopaedics, 15th Ed 2026 and supporting sources.

Phase 0 - Preoperative (Prehabilitation)

Rehabilitation should ideally begin before the operation. A preoperative physiotherapy session covers:
  • Transfers (bed to chair, chair to standing)
  • Correct use of walking aids (walker, crutches, cane)
  • How to negotiate stairs safely
  • Dislocation precautions - movements to avoid post-op
  • Expected discharge process (ambulatory surgery centre or hospital)
A motivated, informed patient with realistic goals is a much better participant in post-op recovery. - Campbell's Operative Orthopaedics, 15th Ed, p. 365

Phase 1 - Immediate Postoperative (Day 0-1)

Positioning

  • Hip positioned in approximately 15 degrees of abduction during anaesthetic recovery
  • Posterior approach (PA): triangular abduction pillow between the thighs to maintain abduction and prevent extremes of flexion; pillows must be strapped carefully to avoid peroneal nerve pressure
  • Direct anterior approach (DAA): a standard pillow may be used instead
  • When sitting: one or two pillows in the seat of the chair to prevent excessive hip flexion; an additional pillow between the thighs limits adduction and internal rotation

Gait Training

  • Gait training begins on the day of surgery in most patients
  • Elderly patients: walker for balance and stability initially
  • Younger patients: typically need a walker for only a few days, then progress more rapidly

Phase 2 - Early Mobilization (Days 1-6, Inpatient)

Weight-Bearing Protocol

The amount of weight bearing allowed depends on:
  • Method of fixation (cemented vs. cementless)
  • Presence of structural bone grafts
  • Stress risers in the femur
  • Whether a trochanteric osteotomy was performed
Fixation TypeWeight Bearing
CementedFull weight bearing to tolerance - immediately
Cementless (porous ingrowth)Some authors restrict to partial WB for 6 weeks; others allow early WB as comfort allows
Cementless - stairsProtected weight bearing on stairs for first few weeks (high torsional loads)
A systematic review (Hol et al., 2010) found no adverse effects on subsidence or osseointegration with unrestricted weight bearing in cementless implants. The decision must be individualized by the surgeon. - Campbell's Operative Orthopaedics, p. 365-366

Activities of Daily Living

  • Bathroom privileges with an elevated toilet seat when the patient can walk far enough with supervision
  • Bedside commode may be used initially
  • Occupational therapy: a few sessions to teach safe dressing, putting on shoes, picking up objects from the floor, and other ADLs
  • Many simple assistive appliances are available (long-handled shoehorn, sock aid, grabber)

Discharge Criteria

The patient can be discharged when able to:
  1. Get in and out of bed independently
  2. Walk over level surfaces
  3. Climb a few steps
Printed home exercise program and dislocation precautions should be provided at discharge.

Phase 3 - Early Home Rehabilitation (Weeks 1-6)

Dislocation Precautions (first 6 weeks)

Movements that increase dislocation risk must be avoided, particularly for the posterior approach:
  • No hip flexion beyond 90°
  • No adduction (crossing legs)
  • No internal rotation
These are particularly important with the posterior approach. A meta-analysis of 9,599 patients from 7 studies found dislocation rates were the same (2.2%) whether or not hip precautions were formally prescribed - suggesting precautions may matter less than previously thought - Campbell's, p. 365.

Practical Restrictions (First 6 Weeks)

  • Use an elevated toilet seat
  • Sleep with one or two pillows between the knees when lying on the non-operative side
  • Showers allowed when wound healing is satisfactory - no baths
  • Sexual activity can be resumed, avoiding extremes of range of motion

Walking Aid Progression

  • Continue two-handed support (walker/frame) until first outpatient visit at 2 weeks
  • At 2-week review: transition to a single cane when strength and balance allow
  • Continue cane use until pain and limp have fully resolved
  • Timing of this transition is best decided between the patient and their supervising physiotherapist

Driving

  • Uncomplicated primary THR: patients usually resume driving at approximately 2-4 weeks
  • Individualized based on return of strength, leg control, and reaction time

Phase 4 - Strengthening and Return to Function (Weeks 6-12+)

Exercise Programme

  • Strengthening exercises - improve gait, balance, and endurance
  • Stretching exercises - continued until the patient can reach the foot for dressing and nail care
    • Foot dressing technique: place the ankle of the operated limb on the opposite knee
  • Note: gait analysis and force-plate data show that recovery of hip abductor muscle strength is prolonged, with persistent abductor weakness still measurable at 1 year post-op (Foucher et al.) - supporting the need for a prolonged exercise regimen beyond the initial weeks

Outpatient / Home Physiotherapy

  • Outpatient or home health physical therapy is historically recommended after hospital discharge
  • Internet-based, self-directed physical therapy has grown in popularity at some centres; however, approximately one-third of patients on self-directed programs were found to require referral back to outpatient PT due to slow recovery (Klement et al., n=941)
  • Patients with multiple joint involvement, pre-existing weakness, or lack of social support may need an inpatient rehabilitation facility before returning to independent living

Phase 5 - Return to Work and Activity (Months 1-3)

ActivityTimeline
Sedentary occupation~4 weeks
Occupation with prolonged standing~2-3 months
Overall return to work (meta-analysis, 57 studies)Mean 11.2 weeks (70% of patients)
Heavy labour / advanced ageLower return-to-work rates

Permitted Activities

  • Safe: swimming, cycling, golf
  • Caution/avoid: jogging, racquet sports, repetitive impact loading, extremes of hip positioning - these may increase the risk of arthroplasty failure

Cardiovascular Benefit

After THR, cardiovascular fitness typically improves - significant improvement in exercise duration, maximal workload, and peak oxygen consumption has been demonstrated vs. medically managed controls (Ries et al.). - Campbell's, p. 366

Follow-Up Schedule

TimeAssessment
2 weeksFirst postoperative clinic visit + radiographs; transition to cane
6 weeksOutpatient review; discontinue most dislocation precautions
1 yearFormal clinic review
Every 2 yearsRoutine radiographs for loosening, migration, wear, implant failure
Regular follow-up is advised because loosening, wear, and osteolysis can occur in the absence of clinical symptoms - and revision surgery is more difficult if diagnosis is delayed until symptoms appear. - Campbell's Operative Orthopaedics, 15th Ed, p. 366

Source: Campbell's Operative Orthopaedics, 15th Ed 2026, Postoperative Management of Total Hip Arthroplasty, pp. 365-366. Supplemented by Bailey and Love's Short Practice of Surgery, 28th Ed; Morgan and Mikhail's Clinical Anesthesiology, 7th Ed.
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