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physiology AND hypoxia

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medical physiology positive feedback osmosis local anaesthetic secretin cardiac plateau hypoxia altitude physiology

Only Page 1 is visible, and Questions 14-15 are partly obscured. Upload a clear image of Page 2 and the lower portion of Page 1 for the complete solved paper.

Answers for visible MCQs

Q.AnswerBrief reason
1d. Thrombolytic activity in coagulation cascadeThis is not a positive-feedback phenomenon.
2b. From B towards AWater moves by osmosis from lower osmolality to higher osmolality.
3b. C typeSmall, unmyelinated C fibers are most sensitive to local anesthetics.
4c. I band becomes widerDuring contraction, I band becomes narrower; A band stays unchanged and Z lines approach.
5a. Meissner’s plexus is responsible for gastrointestinal motilityFalse. Auerbach's/myenteric plexus mainly controls motility; Meissner's plexus controls secretion and local blood flow.
6c. Contraction of pyloric sphincterSecretin stimulates bicarbonate secretion, potentiates CCK action, and inhibits gastric secretion.
7d. HepatocytesBile is produced by hepatocytes.
8a. Blood ureaBlood urea is not a standard liver-function test.
9b. Left ventricle does more work to pump out the bloodIt pumps against the high resistance of systemic circulation.
10b. Slow influx of Ca²⁺ ionsPhase 2 plateau of ventricular action potential is primarily due to slow inward Ca²⁺ current.
11b. AV nodeThe AV node produces the maximal physiological conduction delay.
12a. They require lesser tension to balance the distending pressureBy Laplace law, wall tension is proportional to radius; capillaries have a very small radius.
13c. Histotoxic hypoxiaOxygen administration does not correct defective cellular utilization of oxygen.
14a. HyperventilationThe immediate response to ascent to high altitude is hypoxia-induced hyperventilation.
15b. LeukocytosisAcute infection generally causes leukocytosis, commonly with neutrophilia in bacterial infection.
For Q14, long-term acclimatization also includes increased erythropoiesis and increased RBC 2,3-DPG, but hyperventilation is the early, best single answer.
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