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All questions have been answered. Here is a brief guide to what was covered:

Paper Summary

Section A — Long Answer (Attempt any 2 of 3):
QTopicKey Points Covered
1aMicrobes in immune disorders & NCDsMolecular mimicry, bystander activation, superantigens, oncogenic microbes, gut microbiome functions, dysbiosis
1bBacteriophage typingPrinciple, RTD, detailed procedure for S. aureus, phage sets for S. typhi / Pseudomonas, typing methods comparison, reference centers (NCDC, CRI Kasauli, Institut Pasteur, NCTC)
1cWater quality investigation (4-part clinical scenario)Waterborne diseases, qualitative & quantitative tests, MPN presumptive/confirmed/completed coliform tests, fecal coliform EC test, WHO standards, public health interventions
Section B — Short Answers (Attempt any 6 of 8):
QTopic
2aMycoplasma unique features (no cell wall, cholesterol, fried-egg colonies, UGA codon), pathogenesis of atypical pneumonia, cold agglutinins, diagnosis (UBT, serology, PCR)
2bZoonoses definition, full bacterial zoonoses table, Brucellosis (virulence factors, pathogenesis, SAT/2-ME/RBPT/ELISA/culture/PCR)
2cTB-HIV syndemic biology, NTEP/NACP integration, CBNAAT/TrueNat/LPA, urine LAM, IGRA, Active Case Finding
2dH. pylori virulence (CagA, VacA, urease), ulcer mechanisms, UBT/SAT/CLO/histopathology/culture/PCR
2eLegionella: BCYE agar, Dot/Icm T4SS, urine antigen test, treatment (fluoroquinolones)
2fLyme disease two-tier testing (ELISA + Western blot), PCR in synovial fluid, C6 ELISA, pitfalls
2gAntibiotic audit: PPS, DDD/100 bed-days, WHO AWaRe, PDCA cycle, key indicators
2hBacterial meningitis: CSF analysis table, Gram stain, culture protocol, LAT, multiplex PCR (FilmArray), causative organisms by age

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