Generate antipsychotics topic from KDT pharmacology in a flow chart ma

Generate antipsychotics topic from KDT pharmacology in a flow chart manner

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Antipsychotics Flowchart - KDT Pharmacology

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antipsychotics flowchart
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1. Classification

FGA (Typical): Low potency (Chlorpromazine, Thioridazine) vs. High potency (Haloperidol, Fluphenazine, Pimozide)
SGA (Atypical): D2/5-HT2 blockers vs. Partial agonists (Aripiprazole, Cariprazine, Brexpiprazole)
Chemical classes: Phenothiazines, Butyrophenones, Thioxanthenes

2. Dopamine Pathways - All 4 tracts (Mesolimbic, Mesocortical, Nigrostriatal, Tuberoinfundibular) with clinical implications

3. Mechanism of Action - D2 blockade, D2 + 5-HT2A (SGAs), partial agonism, glutamate hypothesis, clozapine's unique profile

4. Pharmacokinetics - Absorption, distribution, metabolism, depot (LAI) forms

5. Adverse Effects (most detailed section):

EPS flowchart with onset timing: Acute dystonia → Akathisia → Parkinsonism → Tardive dyskinesia
NMS (FALTER mnemonic) with NMS vs. Serotonin Syndrome comparison
Metabolic effects, QTc prolongation, clozapine-specific effects

6. Clinical Uses - Primary indications, non-psychotic uses, treatment algorithm

7. Drug Comparison Table - 10 major drugs compared across EPS, sedation, weight gain, prolactin, QTc

8. Mnemonics - EPS timeline (ADAPT), Clozapine features (CLOZAPINE mnemonic), high-yield exam facts

9. Contraindications & Drug Interactions

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