Electronystagmography and videonystagmography

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electronystagmography videonystagmography vestibular testing ENG VNG

This diagnostic image displays electronystagmography (ENG) or videonystagmography (VNG) tracings recorded during an ophthalmological or vestibular examination. The figure is divided into three sections evaluating eye movement dynamics. The top panel depicts 'Horizontal Eye Position [°]', showing a classic sawtooth wave pattern of spontaneous left-beating nystagmus characterized by a slow rightward drift and a rapid leftward corrective phase. The middle panel shows stable 'Vertical Eye Position [°]' with minimal deviation. The bottom panel illustrates 'Horizontal Eye Position' during a smooth pursuit task, featuring a green sinusoidal target line superimposed with red and blue eye-tracking lines. These tracings exhibit significant saccadic intrusions and oscillations, indicating broken or fragmented pursuit movements where the patient employs catch-up saccades to track the target. The data demonstrates a congenital-type horizontal conjugate nystagmus that intensifies during tracking, relevant for neuro-otological and vestibular diagnostics.

This diagnostic image displays electronystagmography (ENG) or videonystagmography (VNG) tracings recorded during an ophthalmological or vestibular examination. The figure is divided into three sections evaluating eye movement dynamics. The top panel depicts 'Horizontal Eye Position [°]', showing a classic sawtooth wave pattern of spontaneous left-beating nystagmus characterized by a slow rightward drift and a rapid leftward corrective phase. The middle panel shows stable 'Vertical Eye Position [°]' with minimal deviation. The bottom panel illustrates 'Horizontal Eye Position' during a smooth pursuit task, featuring a green sinusoidal target line superimposed with red and blue eye-tracking lines. These tracings exhibit significant saccadic intrusions and oscillations, indicating broken or fragmented pursuit movements where the patient employs catch-up saccades to track the target. The data demonstrates a congenital-type horizontal conjugate nystagmus that intensifies during tracking, relevant for neuro-otological and vestibular diagnostics.

Diagnostic diagnostic traces and charts showing results of a caloric vestibular test, used to assess peripheral vestibular function. The top four panels display Electronystagmography (ENG) or Videonystagmography (VNG) recordings of slow phase velocity (SPV) in degrees per second (°/s) during bithermal caloric irrigation (30°C cold and 44°C hot) for both the left and right ears. The left ear panels demonstrate characteristic nystagmus responses with fluctuating SPV values. In contrast, the right ear panels ('Right; cold' and 'Right; hot') show flat traces with SPV peak values ≤ 5°/s, indicating a diagnosis of right vestibular areflexia. The bottom left quadrant contains a composite scatter plot of nystagmus velocity over time, with red and blue data points representing the fast and slow phases of nystagmus. The bottom right graph provides a summary caloric chart plotting peak velocities to quantify vestibular paresis or directional preponderance. This material is essential for neurology and otolaryngology students studying the diagnostic workup of vertigo, balance disorders, and unilateral vestibular loss.

Diagnostic diagnostic traces and charts showing results of a caloric vestibular test, used to assess peripheral vestibular function. The top four panels display Electronystagmography (ENG) or Videonystagmography (VNG) recordings of slow phase velocity (SPV) in degrees per second (°/s) during bithermal caloric irrigation (30°C cold and 44°C hot) for both the left and right ears. The left ear panels demonstrate characteristic nystagmus responses with fluctuating SPV values. In contrast, the right ear panels ('Right; cold' and 'Right; hot') show flat traces with SPV peak values ≤ 5°/s, indicating a diagnosis of right vestibular areflexia. The bottom left quadrant contains a composite scatter plot of nystagmus velocity over time, with red and blue data points representing the fast and slow phases of nystagmus. The bottom right graph provides a summary caloric chart plotting peak velocities to quantify vestibular paresis or directional preponderance. This material is essential for neurology and otolaryngology students studying the diagnostic workup of vertigo, balance disorders, and unilateral vestibular loss.

This diagnostic image displays four electronystagmography (ENG) or videonystagmography (VNG) recordings of vertical eye motion in a patient undergoing a motorized rotation chair test. The traces correspond to four different head rotation velocities: 10°/s, 20°/s, 30°/s, and 40°/s. Each recording depicts paroxysmal downbeat nystagmus (DBN) induced during a positioning phase, indicated by shaded pink rectangular areas. There is a direct correlation between rotation velocity and nystagmus intensity; as the velocity increases from 10 to 40°/s, both the amplitude and frequency of the downward deflections (downbeat nystagmus) increase significantly. Following the cessation of positioning, the paroxysmal downbeat nystagmus typically transitions into a lower-amplitude upward deflection, representing a brief upbeat nystagmus. A scale bar at the bottom right indicates 10° for vertical displacement and 1 second for time. This visual aids in understanding the velocity-dependent nature of central positional nystagmus (CPN) and its diagnostic patterns in neuro-otology.

This diagnostic image displays four electronystagmography (ENG) or videonystagmography (VNG) recordings of vertical eye motion in a patient undergoing a motorized rotation chair test. The traces correspond to four different head rotation velocities: 10°/s, 20°/s, 30°/s, and 40°/s. Each recording depicts paroxysmal downbeat nystagmus (DBN) induced during a positioning phase, indicated by shaded pink rectangular areas. There is a direct correlation between rotation velocity and nystagmus intensity; as the velocity increases from 10 to 40°/s, both the amplitude and frequency of the downward deflections (downbeat nystagmus) increase significantly. Following the cessation of positioning, the paroxysmal downbeat nystagmus typically transitions into a lower-amplitude upward deflection, representing a brief upbeat nystagmus. A scale bar at the bottom right indicates 10° for vertical displacement and 1 second for time. This visual aids in understanding the velocity-dependent nature of central positional nystagmus (CPN) and its diagnostic patterns in neuro-otology.

A compilation of three-dimensional videonystagmography (VNG) recordings illustrating stimulus-evoked vestibular-induced nystagmus (SVIN) in a patient with left superior semicircular canal dehiscence (uSCD). The panels display horizontal (H, red), vertical (V, green), and torsional (T, blue) ocular motor components across four bone conduction frequencies: 60 Hz, 100 Hz, 200 Hz, and 300 Hz. The recordings compare different stimulation sites including the left mastoid (LM), right mastoid (RM), vertex (Vx), and baseline no stimulation (N). Key findings demonstrate that the horizontal and torsional components remain consistently left-beating across all frequencies, particularly during vertex stimulation. In contrast, the vertical component exhibits frequency-dependent directionality: it is up-beating (indicated by upward arrows) at 60, 100, and 200 Hz, but reverses to a down-beating pattern (indicated by downward arrows) at 300 Hz. This clinical diagnostic image illustrates the use of high-frequency vibration to evaluate vestibular hypersensitivity and identify semicircular canal pathology.

A compilation of three-dimensional videonystagmography (VNG) recordings illustrating stimulus-evoked vestibular-induced nystagmus (SVIN) in a patient with left superior semicircular canal dehiscence (uSCD). The panels display horizontal (H, red), vertical (V, green), and torsional (T, blue) ocular motor components across four bone conduction frequencies: 60 Hz, 100 Hz, 200 Hz, and 300 Hz. The recordings compare different stimulation sites including the left mastoid (LM), right mastoid (RM), vertex (Vx), and baseline no stimulation (N). Key findings demonstrate that the horizontal and torsional components remain consistently left-beating across all frequencies, particularly during vertex stimulation. In contrast, the vertical component exhibits frequency-dependent directionality: it is up-beating (indicated by upward arrows) at 60, 100, and 200 Hz, but reverses to a down-beating pattern (indicated by downward arrows) at 300 Hz. This clinical diagnostic image illustrates the use of high-frequency vibration to evaluate vestibular hypersensitivity and identify semicircular canal pathology.

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Electronystagmography (ENG) and Videonystagmography (VNG)

ENG/VNG is the most commonly employed method of laboratory evaluation of the vestibular system. Both techniques exploit the close anatomical link between the vestibular and ocular systems via the vestibulo-ocular reflex (VOR): peripheral or central vestibular disorders produce abnormal eye movements that can be measured, recorded, and analyzed.

1. Basic Principles

ENG

  • Records eye movements indirectly by measuring changes in the corneoretinal potential (CRP) - a steady DC dipole (cornea positive relative to retina, ~1 mV in primary gaze) that rotates with the eyes.
  • Skin surface electrodes are placed at each lateral canthus (horizontal movements) and above/below one eye (vertical movements), with a common ground on the forehead.
  • As the eyes rotate, the electric field shifts, causing voltage changes proportional to eye position.
  • Limitation: cannot detect torsional nystagmus (rotation about the pupil axis does not change the CRP). ENG also picks up more artifact from lid movements and muscle potentials ("noisier" signal).

VNG

  • Records eye movements directly using infrared video cameras and digital image-processing technology.
  • Eye movements can be observed in real time and/or recorded for review later.
  • Advantage over ENG: allows the clinician to go back and visually review the actual recording; enables torsional eye movement measurement (though technology continues to evolve); shows actual nystagmus morphology clearly.
  • Disadvantage: cannot record eye movements with eyes closed; head-mounted goggles can be harder to stabilize.
  • ENG hardware costs less and still provides reliable clinical data for most purposes.
Other recording technologies include magnetic search coils (most accurate, especially for torsion) and electro-oculography (EOG).

2. Physiological Basis - Corneoretinal Potential

The CRP is generated by metabolic activity of the retinal pigment epithelium. The retina is electronegative relative to the cornea. In primary gaze, ~1 mV is measured at the cornea. Rotation of the eye rotates this electric field, producing a roughly linear change in voltage between temple electrodes. By convention:
  • Rightward eye movement = upward deflection on the tracing
  • Leftward eye movement = downward deflection

3. The ENG/VNG Test Battery

The exam is organized into three groups of tests:

Group 1 - Visual-Oculomotor (Non-vestibular Eye Movements)

TestWhat it assesses
Saccade testSaccadic control system; patient "jumps" gaze between targets 10-30° apart. Normal saccade peak velocity: up to 700°/s, average ~200°/s. Evaluates accuracy (normal vs. dysmetric), latency, velocity
Smooth pursuit testPursuit control system; patient tracks a slow sinusoidal target. Reports gain (eye velocity/target velocity), phase, symmetry
Optokinetic nystagmus (OKN)Pursuit and optokinetic reflex; patient watches a large moving visual field
Fixation testStability of gaze fixation

Group 2 - Static and Dynamic Positional Tests

TestWhat it assesses
Gaze testSpontaneous nystagmus in primary gaze and at ~30° eccentricity (eyes open in light vs. darkness); gaze-evoked nystagmus
Positional testHead tilted into various static positions - detects positional nystagmus; abnormal if slow-phase velocity >4°/s
Dix-Hallpike maneuverPositioning nystagmus; characteristic burst in BPPV
Fistula testPressure-induced nystagmus (perilymph fistula or superior semicircular canal dehiscence)

Group 3 - Vestibulo-Oculomotor Function

Bithermal caloric test - the single most indispensable test in the ENG/VNG battery. Evaluates the lateral (horizontal) semicircular canal specifically and allows each labyrinth to be assessed independently.

4. Bithermal Caloric Test (Jongkees Formula)

Stimulus parameters:
  • Water: body temperature ±7°C → 30°C (cool) and 44°C (warm), irrigated for 30 seconds
  • Air: body temperature ±13°C → 24°C (cool) and 58°C (warm), irrigated for 60 seconds
  • Patient positioned supine with head elevated 30° (brings the lateral SCC into the vertical plane, maximizing convection)
The COWS mnemonic:
Cold - Opposite, Warm - Same
The fast phase of the induced nystagmus beats:
  • Cold irrigation → endolymph cools → fluid density rises → falls → ampullofugal flow in the lateral SCC → hair cell deflection away from kinocilium → inhibition → slow drift of eyes toward the irrigated side → fast (compensatory) saccades toward the opposite side
  • Warm irrigation → endolymph rises → ampullopetal flow → excitation → fast phase toward the same side as irrigation
Jongkees formulae (peak slow-phase eye velocity used throughout):
Unilateral Weakness (UW) - canal paresis:
$$UW = \frac{(RW + RC) - (LW + LC)}{RW + RC + LW + LC} \times 100%$$
  • Abnormal if UW >15-30% (lab-dependent threshold)
  • Indicates hypofunctional labyrinth on the weaker side
Directional Preponderance (DP):
$$DP = \frac{(RW + LC) - (LW + RC)}{RW + RC + LW + LC} \times 100%$$
  • Abnormal if DP >30%
  • Clinical value is debated; some believe DP points toward a central lesion and away from a peripheral lesion
Bilateral weakness: Total summed response for each side <12°/s (i.e., LW + LC <12°/s and RW + RC <12°/s)
Practical contraindications/cautions:
  • Water irrigation is contraindicated with TM perforation (use air instead; note the perforated side gives a heightened response to air)
  • Remove excess cerumen before testing
  • Perform otoscopy first

5. ENG/VNG Interpretation

Findings suggesting PERIPHERAL pathology:

  • Unilateral caloric weakness
  • Bilateral caloric weakness with a history of labyrinthine disease or ototoxicity
  • Fatiguing positional nystagmus (e.g., BPPV pattern)
  • Intact fixation suppression (patient can suppress nystagmus with visual fixation)
  • Direction-fixed nystagmus

Findings suggesting CENTRAL pathology:

  • Spontaneous or positional nystagmus with normal calorics
  • Direction-changing nystagmus
  • Failure of fixation suppression (cannot suppress nystagmus when fixating)
  • Bilateral absent/reduced caloric responses without a history of labyrinthine disease or ototoxicity
  • Abnormal saccades or saccadic pursuit with normal caloric results
  • Hyperactive caloric responses (loss of cerebellar inhibition, in absence of TM defect or mastoid cavity)

6. Oculomotor Patterns on ENG/VNG Recordings

The diagram below from Bradley and Daroff's Neurology shows normal and abnormal patterns:
ENG/VNG oculomotor recordings - normal vs abnormal saccades, smooth pursuit, and OKN
Key abnormal patterns:
  • Slow saccades - pontine or extraocular muscle disease
  • Dysmetric saccades - cerebellar disorder
  • Symmetrically or asymmetrically impaired smooth pursuit - central pathology
  • Decreased OKN fast-phase velocity - pursuit system dysfunction
  • Decreased OKN slow-phase velocity - optokinetic reflex impairment

7. Caloric Test Recordings

A real caloric test output showing right vestibular areflexia (flat right-ear traces) with normal left-ear responses:
Caloric test ENG/VNG recordings showing right vestibular areflexia

8. Clinical Uses of ENG/VNG

As listed by Shambaugh (Surgery of the Ear):
Purpose
Aid in establishing diagnosis (central vs. peripheral)
Lateralization of dysfunction
Documentation of degree of dysfunction
Assist in devising treatment plan
Aid in long-term management and monitoring

9. ENG vs. VNG - Comparison Summary

FeatureENGVNG
PrincipleCorneoretinal potential (indirect)Infrared video camera (direct)
ElectrodesSkin surface electrodesVideo goggles
CostLowerHigher
Artifact/noiseMore (lid, muscle)Less
Torsional nystagmusCannot detectCan detect (developing)
Closed-eye recordingYesNo
Video review of eye movementsNoYes (key advantage)
Fixation removalRequires eye closureGoggles in darkness

Sources:
  • K.J. Lee's Essential Otolaryngology, p. 351-352
  • Shambaugh Surgery of the Ear, pp. 248-250+
  • Bradley and Daroff's Neurology in Clinical Practice, p. 377
  • Cummings Otolaryngology Head and Neck Surgery
  • Scott-Brown's Otorhinolaryngology Head & Neck Surgery, Vol. 2
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