Primary diagnosis
Chronic coronary syndrome (stable exertional angina) due to suspected obstructive coronary artery disease, Canadian Cardiovascular Society (CCS) class III.
Viva answer: How do you prove it?
This patient has typical angina pectoris because the chest pain has all three classical features:
- Constricting retrosternal chest pain
- Precipitated by exertion: walking about 200 m or climbing one flight of stairs
- Relieved by rest within 3-5 minutes
It radiates to the left shoulder, which further supports myocardial ischemia.
His symptoms have been present for about 1.5 years, with no pain at rest and a predictable exertional pattern. Therefore, it is stable angina, now termed a chronic coronary syndrome, rather than acute coronary syndrome.
Why CCS class III?
He develops angina after walking only 200 m or climbing one flight of stairs. This represents a marked limitation of ordinary physical activity, consistent with CCS class III angina.
Evidence supporting coronary artery disease
He has multiple atherosclerotic risk factors:
- Male, 55 years
- Hypertension
- Dyslipidemia: total cholesterol 6.5 mmol/L, LDL-C 3.5 mmol/L, triglycerides 2.7 mmol/L
- Past smoking history
- Central obesity: waist circumference 96 cm
- Family history of premature myocardial infarction: father died at age 59
Test evidence
The resting ECG is normal, which does not exclude stable coronary artery disease.
The exercise ECG was stopped at 75 W because of chest discomfort and showed 2 mm ST-segment depression in V4, V5, and V6.
This is a positive exercise stress test because exercise-induced horizontal or downsloping ST depression of at least 1 mm is diagnostic of inducible myocardial ischemia when the resting ECG is interpretable. His 2 mm depression in contiguous lateral precordial leads, associated with typical chest pain, strongly supports exercise-induced subendocardial ischemia.
The likely ischemic territory is anterolateral/lateral myocardium.
One-line examination answer
“This is chronic coronary syndrome presenting as typical stable exertional angina, CCS class III, with a positive exercise ECG for inducible myocardial ischemia, most likely due to obstructive coronary artery disease.”
How to confirm anatomically
A positive exercise test supports ischemia but does not show the coronary anatomy. Confirmation can be by:
- Coronary CT angiography in suitable patients, or
- Invasive coronary angiography, especially because he has class III symptoms, early positive stress testing, and significant ST depression.
Modern ESC guidance uses clinical likelihood plus non-invasive anatomical or functional imaging for suspected chronic coronary syndrome; invasive angiography is appropriate when symptoms are severe or risk is high.
2024 ESC chronic coronary guidance notes that exercise ECG alone is less accurate than imaging-based tests, although it remains useful for exercise capacity, symptom reproduction, and ECG ischemia assessment.
Important viva point: Say “positive for exercise-induced myocardial ischemia”, not “the treadmill test proves coronary blockage.” The blockage must be demonstrated by CT coronary angiography or invasive coronary angiography.