Diabetes mellitus is best learned as a connected system rather than a list of facts. Here is the learning map:
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Foundations
- Normal glucose and insulin physiology
- What diabetes is and why hyperglycemia occurs
- Classification: type 1, type 2, gestational diabetes, and secondary forms
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Diagnosis and screening
- Fasting glucose, HbA1c, oral glucose-tolerance test, random glucose
- Prediabetes
- Who should be screened and when
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Type 1 diabetes
- Autoimmune beta-cell destruction and insulin deficiency
- Clinical presentation, honeymoon phase, lifelong insulin replacement
- Diabetic ketoacidosis (DKA)
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Type 2 diabetes
- Insulin resistance plus progressive beta-cell dysfunction
- Risk factors, natural history, presentation
- Lifestyle therapy and medication selection
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Treatment
- Nutrition, activity, weight management, sleep, smoking cessation
- Insulin types and regimens
- Metformin, GLP-1 receptor agonists, SGLT2 inhibitors, sulfonylureas, DPP-4 inhibitors, thiazolidinediones, and others
- Continuous glucose monitoring and insulin pumps
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Acute complications
- Hypoglycemia
- DKA
- Hyperosmolar hyperglycemic state (HHS)
- Sick-day management
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Chronic complications
- Eye disease: retinopathy
- Kidney disease: albuminuria and chronic kidney disease
- Nerve disease: peripheral and autonomic neuropathy
- Diabetic foot ulcers and infections
- Cardiovascular disease, stroke, peripheral arterial disease
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Monitoring and prevention
- Glucose targets, HbA1c targets, time-in-range
- Blood pressure and lipid control
- Vaccination, kidney screening, eye exams, foot checks
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Special situations
- Pregnancy and gestational diabetes
- Children and adolescents
- Older adults
- Chronic kidney disease, heart failure, surgery, fasting, and illness
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Clinical reasoning
At its core, diabetes is a disorder of glucose regulation caused by inadequate insulin action, inadequate insulin production, or both. Type 1 diabetes is primarily an absolute insulin-deficiency state; type 2 is primarily insulin resistance with eventual beta-cell failure. The main goals are to reduce symptoms and prevent hypoglycemia, acute metabolic emergencies, and long-term vascular, kidney, nerve, and eye complications.
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Foundations and classification
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Diagnosis and tests
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Type 1 diabetes and DKA
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Type 2 diabetes and medications
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Insulin and glucose monitoring
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Complications
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Full beginner-to-clinical lesson planA full beginner-to-advanced course has several distinct tracks. I can teach it in short lessons, build each concept on the prior one, and include recall questions and clinical cases.
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Core physiology: glucose handling, insulin, glucagon, fasting versus fed state
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Classification and causes: type 1, type 2, gestational, monogenic, pancreatic and drug-induced diabetes
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Diagnosis: fasting plasma glucose, HbA1c, oral glucose tolerance testing, prediabetes, pitfalls
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Type 1 diabetes: autoimmune beta-cell destruction, presentation, insulin, DKA
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Type 2 diabetes: insulin resistance, beta-cell failure, obesity, cardiometabolic risk
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Lifestyle and self-management: food patterns, carbohydrate concepts, exercise, weight, monitoring
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Glucose-lowering medicines: metformin, GLP-1 medicines, SGLT2 inhibitors, insulin, and less-used classes
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Insulin in depth: basal-bolus physiology, dose adjustment principles, pumps and continuous glucose monitoring
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Acute emergencies: hypoglycemia, DKA, hyperosmolar hyperglycemic state
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Long-term complications: retinopathy, kidney disease, neuropathy, diabetic foot disease, cardiovascular disease
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Prevention and follow-up: screening, HbA1c and time-in-range, blood pressure, lipids, vaccinations, examinations
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Advanced and special contexts: pregnancy, children, older adults, kidney disease, heart failure, inpatient care, surgery, and clinical case reasoning
High-level anchor: diabetes is chronic hyperglycemia due to too little insulin, reduced tissue response to insulin, or both. It is not managed by glucose numbers alone: good care also addresses cardiovascular and kidney risk, hypoglycemia prevention, complications, access, and the person’s circumstances.
Choose the learning format so I can start Lesson 1 at the right level.Reply with one choice for each: