I now have the key textbook content. The mechanism is clearly described. Let me compile the answer.
Right Cheek Pain Only When Lying Down
The most likely explanation is maxillary sinusitis — and the positional pattern is a textbook diagnostic clue.
Why Position Matters: The Mechanism
The maxillary sinuses sit behind each cheek. Their drainage openings (ostia) are positioned near the top of the sinus cavity — a poor anatomical design. When you are upright, secretions can drain under gravity, relieving pressure. When you lie down, drainage becomes impaired, secretions pool, and pressure builds against the sinus walls, causing pain.
This is the inverse of frontal/ethmoidal sinusitis, which is worse on awakening and improves on standing. Maxillary sinusitis pain worsens when lying down — exactly what you describe.
"With frontal and ethmoidal sinusitis, the pain tends to be worse on awakening and gradually subsides when the patient is upright; the opposite pertains with maxillary and sphenoidal sinusitis. These relationships... pain is ascribed to filling of the sinuses and its relief to their emptying, induced by the dependent position of the ostia."
— Adams and Victor's Principles of Neurology, 12th Edition
"Maxillary sinusitis causes pain and tenderness over the cheek."
— Bradley and Daroff's Neurology in Clinical Practice
Other Things to Consider
| Cause | Why it can cause positional cheek pain | Distinguishing features |
|---|
| Maxillary sinusitis | Sinus fills when lying down; ostia drain poorly | Nasal congestion, facial tenderness, worse with colds/allergies |
| Dental abscess (upper molar) | Upper teeth roots sit near the maxillary sinus floor | Tooth pain, sensitivity to hot/cold, gum swelling |
| TMJ disorder | Jaw muscle tension increases when lying on one side | Jaw clicking, ear pain, worse with chewing |
| Trigeminal neuralgia | Nerve compression; position can affect blood vessel pressure on nerve | Electric-shock quality pain, triggered by touch or chewing |
| Referred tooth pain | Nerve overlap between upper teeth and cheek | Dental exam needed |
What Helps
- Decongestants (e.g. pseudoephedrine, phenylephrine nasal spray) reduce mucosal swelling, help the sinus drain, and typically relieve the pain — this response is itself diagnostic of sinusitis.
- Sleeping with head elevated (extra pillow) reduces sinus filling.
- Saline nasal rinses to aid drainage.
- NSAIDs (ibuprofen) for pain and inflammation.
If this is recurrent, accompanied by fever, thick colored nasal discharge, or if pain is severe, see a doctor — bacterial sinusitis may need antibiotics, and chronic or structural causes (deviated septum, polyps) may need further evaluation.