Pt fibeoscan
I'll read the FibroScan report from the image and interpret it for you.
Patient: Savitri Manganure, F, DOB 01/06/1971 (age ~54)
Height: 158 cm | Weight: 68 kg | Indication: NAFLD/NASH | Fasting: Yes
Date: 20/05/2026
FibroScan Results
| Parameter | Value | Significance |
|---|---|---|
| LSM (Liver Stiffness) - Median E | 6.9 kPa | Fibrosis stage |
| IQR/Med | 9% | Reliability indicator |
| CAP (Controlled Attenuation Parameter) | 269 dB/m | Steatosis grade |
| SD | 11 | |
| SWF | 50 Hz | |
| Valid measurements | 10 |
Interpretation (NAFLD/NASH context)
Liver Stiffness - 6.9 kPa
Using standard NAFLD thresholds (M probe):
| Stage | kPa Range |
|---|---|
| F0-F1 (no/mild fibrosis) | < 7.0 kPa |
| F2 (significant fibrosis) | 7.0 - 8.7 kPa |
| F3 (advanced fibrosis) | 8.8 - 10.3 kPa |
| F4 (cirrhosis) | > 10.3 kPa |
LSM of 6.9 kPa = borderline F1/F2 - at the upper limit of mild fibrosis, just below the F2 threshold. This is a clinically important value to watch closely.
Steatosis (CAP) - 269 dB/m
| Grade | CAP Range |
|---|---|
| S0 (none) | < 238 dB/m |
| S1 (mild, >11%) | 238 - 259 dB/m |
| S2 (moderate, >33%) | 260 - 290 dB/m |
| S3 (severe, >66%) | > 290 dB/m |
CAP 269 dB/m = Grade S2 (moderate steatosis, >33% hepatic fat)
Reliability
- IQR/Med of 9% is excellent (< 10% = highly reliable result)
- 10 valid measurements - technically satisfactory
Summary & Clinical Notes
- Moderate hepatic steatosis (S2) consistent with NAFLD
- Liver stiffness 6.9 kPa - borderline, just at the F1/F2 transition; no cirrhosis
- Result is technically reliable (IQR/Med 9%, fasting state confirmed)
- The SD of 11 for CAP is within acceptable range
Recommendations to consider:
- Lifestyle modification - weight loss (even 5-10% body weight reduces both steatosis and fibrosis)
- Rule out/manage metabolic syndrome components (T2DM, dyslipidaemia, hypertension)
- Repeat FibroScan in 12 months to monitor progression
- If LSM crosses 7.0-8.7 kPa on repeat, consider liver biopsy or further evaluation for significant fibrosis (F2)
- Check LFTs, fasting lipids, HbA1c if not already done
Is this reversible
Searching PubMed
NAFLD fibrosis regression weight loss lifestyle intervention
Finding Sources
Searching PubMed
NAFLD steatosis reversal weight loss
Here is a thorough answer based on well-established evidence:
Yes - This is Reversible
At 6.9 kPa (borderline F1) + S2 steatosis, Savitri is in the best possible window for reversal. This stage has not crossed into established cirrhosis (F4), which is largely irreversible.
What Can Reverse
1. Hepatic Steatosis (Fat) - Highly Reversible
- 5-7% body weight loss resolves steatosis in the majority of patients
- At 68 kg, that means losing just 3-5 kg can significantly reduce liver fat
- The CAP drop on FibroScan is often measurable within 3-6 months of dietary change
- Even short-term caloric restriction (2-4 weeks) begins reducing hepatic fat
2. Early Fibrosis (F1) - Also Reversible
- F1 fibrosis involves periportal collagen deposition which is metabolically active - the liver can reabsorb it
- Studies consistently show F1-F2 fibrosis regresses with sustained weight loss and metabolic control
- 10% weight loss = >40% chance of fibrosis regression in NAFLD patients
- The liver at this stage still has full regenerative capacity
What Drives Reversal - Practical Steps
| Intervention | Expected Benefit |
|---|---|
| 5% weight loss | Steatosis reduction (CAP falls) |
| 7-10% weight loss | Fibrosis regression (kPa falls) |
| Mediterranean diet | Reduces hepatic fat independent of weight |
| 150-200 min/week aerobic exercise | Reduces liver fat even without weight loss |
| Control blood sugar (HbA1c < 7) | Slows fibrosis progression |
| Avoid alcohol completely | Prevents additive liver injury |
| Avoid hepatotoxic drugs | NSAIDs, unnecessary supplements - avoid |
What to Track at 12 Months
- Repeat FibroScan - target LSM < 6.0 kPa and CAP < 238 dB/m
- Weight loss record
- HbA1c, fasting lipids, ALT/AST
Bottom Line
Savitri's liver is not yet scarred beyond repair. The 6.9 kPa reading is a warning signal at just the right time. With consistent lifestyle change over 6-12 months, both the fat and the early stiffness are fully reversible. The key is acting now before it crosses into F2-F3 territory, where reversal becomes harder and slower.
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