Syp iron 12.5 kg female

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Iron Syrup Dosing - 12.5 kg Female Child

Standard Iron Syrup Formulation

Most commercially available pediatric iron syrups (e.g., Ferrous Sulfate, Ferrous Ascorbate, or Ferric Ammonium Citrate syrups) contain 25 mg elemental iron per 5 mL (1 teaspoon).

Dose Calculation for 12.5 kg

PurposeDoseCalculation (12.5 kg)Volume (25 mg/5 mL syrup)
Treatment (iron deficiency anemia)3-6 mg/kg/day elemental iron37.5 - 75 mg/day7.5 - 15 mL/day
Standard treatment dose3 mg/kg/day (in 2 divided doses)~37.5 mg/day~7.5 mL/day (given as ~3.75 mL twice daily)
Prophylaxis / supplementation1-2 mg/kg/day12.5 - 25 mg/day2.5 - 5 mL/day
Practical prescription for treatment:
Syrup Iron (25 mg elemental iron / 5 mL) - 5 mL (1 tsp) TWICE daily, given between meals
This gives ~50 mg elemental iron/day (~4 mg/kg/day), a well-tolerated therapeutic dose.

Key Dosing Rules

  • Treatment of iron deficiency anemia: 3-6 mg/kg/day of elemental iron, given in 2-3 divided doses, between meals - [Rosen's Emergency Medicine](standard ref); per [Park's Preventive Medicine](ref: elemental iron 3 mg/kg/day in two divided doses, preferably between meals)
  • Prophylaxis (breastfed infants/preterm): 2 mg/kg/day - Harriet Lane Handbook, 23rd ed.
  • Children weighing 15-30 kg can take half the average adult dose - Goodman & Gilman's Pharmacological Basis of Therapeutics
  • Avoid giving iron with food - absorption is reduced by meals, antacids, and tea
  • Vitamin C (ascorbic acid) co-administration improves absorption

Duration of Therapy

  • Continue for 3 months after Hb normalizes to replenish iron stores
  • Hemoglobin typically rises at ~1-2 g/dL per month with adequate treatment
  • Recheck CBC at 4 weeks to confirm response

Common Iron Syrups in India (reference)

BrandElemental IronVolume for this child
Ferrous sulfate syrup (25 mg/5 mL)25 mg/5 mL5 mL BD
Ferrous ascorbate + folic acid syrup30 mg/5 mL4 mL BD
Autrin / Orofer syrupvariable - check labelper label
Important: Always verify the elemental iron content per mL on the label before prescribing, as formulations vary significantly between brands.
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