Dosage of drop iron ascorbate and folic acids for 18 month , 8 kg patient

Reading File
Searching for pediatric dosing of iron, ascorbic acid, and folic acid for infants/toddlers.
search_medical_text

iron drops dosage pediatric infants toddlers mg/kg

Care of the Preterm or Low-Birth-Weight Infant

Page 56

search_medical_text

folic acid dosage infants toddlers supplementation

Haemoglobin Cutoffs to Define Anaemia in Individuals and Populations

Page 65

GradeResponse
GradeResponse
Based on retrieved sources and standard pediatric pharmacology references, here is the dosing guidance for a 18-month-old child weighing 8 kg:

Iron Ascorbate + Folic Acid Drops — Pediatric Dosing (8 kg, 18 months)

1. Elemental Iron (as Iron Ascorbate Drops)

IndicationDoseFor 8 kg child
Prevention / Prophylaxis2–3 mg/kg/day elemental iron16–24 mg/day
Treatment of Iron Deficiency Anemia (IDA)3–6 mg/kg/day elemental iron24–48 mg/day
Typical commercial iron drop concentration: 15 mg elemental iron per 1 mL (varies by brand — always verify the label).
Example (15 mg/mL drops):
  • Prophylaxis: ~1–1.5 mL/day
  • Treatment: ~1.5–3 mL/day
  • Given once or twice daily, preferably on an empty stomach or with citrus juice/water to enhance absorption.
  • Ascorbic acid (vitamin C) in the formulation already enhances iron absorption — no separate vitamin C supplement typically needed.

2. Folic Acid

IndicationDose
Supplementation / Prevention50–100 mcg/day (infants & toddlers under 3 years)
Treatment of folate deficiency500 mcg/day for 4 weeks, then maintenance
At 18 months, the standard supplementation dose is 50–100 mcg/day (0.05–0.1 mg/day). Most combination iron + folic acid drops contain 100–500 mcg folic acid per mL — check the specific product insert.

Key Administration Points

  • Timing: Give drops 30–60 minutes before meals for best absorption.
  • Avoid: Co-administration with cow's milk or calcium-rich foods (inhibit iron absorption).
  • Staining: Iron drops may stain teeth — administer via dropper toward the back of the mouth; rinse/wipe gums after.
  • Duration: For IDA treatment, continue for 3 months after Hb normalizes to replenish stores.
  • Monitor: Recheck Hb/CBC after 4 weeks to confirm response.

Note: Always verify the elemental iron content per mL on the specific product being dispensed (e.g., Ferrous ascorbate 30 mg = ~9.8 mg elemental iron). Dose is calculated on elemental iron, not the total salt weight. Consult national formulary or product insert for exact volume to prescribe.

32 mg/ day how much ML or drops ??

I need the specific product/brand to calculate accurately, but here is the standard calculation:

Most Common Iron Ascorbate Drop Formulations

Brand (common)Concentration32 mg elemental iron =
Ferrous Ascorbate 30 mg/mL (elemental iron ~9.8 mg/mL)~9.8 mg elemental Fe per mL~3.3 mL/day
Ferrous Ascorbate drops (15 mg elemental Fe/mL)15 mg elemental Fe per mL~2.1 mL/day
Standard pediatric iron drops (25 mg Fe/mL)25 mg elemental Fe per mL~1.3 mL/day

Most Commonly Available: Ferrous Ascorbate Drops

Ferrous Ascorbate 75 mg + Folic Acid 500 mcg per mL is widely used.
  • Ferrous ascorbate 75 mg contains approximately 24.5 mg elemental iron per mL
Target doseCalculationVolume
32 mg elemental iron32 ÷ 24.5~1.3 mL/day
If the dropper delivers ~0.5 mL per drop-full (calibrated dropper):
  • → Give 1.5 mL once daily (rounds to nearest practical dose)

Practical Advice

  • Check the label for mg of elemental iron per mL — this varies by brand.
  • Divide into 2 doses (16 mg × 2) if GI side effects occur.
  • Formula: Volume (mL) = Target dose (mg) ÷ Elemental iron per mL
Share the brand name or label details and I can give you the exact mL/drops.

If in 5 mg in 1 mL than ??

Simple Calculation

Concentration: 5 mg elemental iron per 1 mL
32 mg ÷ 5 mg/mL = 6.4 mL/day

Practical Dosing

Dose splitVolume per dose
Once daily6.4 mL
Twice daily3.2 mL per dose

Tip: Twice daily dosing (3.2 mL × 2) is better tolerated in toddlers — reduces GI side effects like constipation and nausea.
If the dropper is 1 mL calibrated, give 3 full droppers twice daily (= 3 mL × 2 = 6 mL ≈ close enough, or 3.2 mL × 2 for precision using a syringe).
Use a 1 mL or 5 mL oral syringe for accurate measurement rather than a dropper.
attachment
attachment

Patient present with hypomennorhea and days of her cycle are normal. What to do how to treat

Reading File
Reading File
analyse_media
The report shows marked biochemical hyperthyroidism, which can contribute to lighter periods. I’ll outline the immediate next steps and when urgent care is needed.
Finding Sources
Finding Sources
Searching PubMed

hyperthyroidism AND menstrual

Searching the Web

American Thyroid Association hyperthyroidism diagnosis treatment patient information menstrual periods

The report is consistent with overt hyperthyroidism (thyrotoxicosis):
  • T3: 381 ng/dL - high
  • T4: 21.3 µg/dL - high
  • TSH: 0.019 µIU/mL - markedly low
This can cause hypomenorrhea: periods occurring at usual intervals but with unusually scanty flow. Textbooks describe scanty and/or irregular menstrual bleeding as common in hyperthyroidism. Tietz Textbook of Laboratory Medicine, p. 4340-4345. The American Thyroid Association also notes that hyperthyroidism may make menstrual flow lighter and periods less frequent (ATA patient information).

What to do

  1. Arrange an endocrinology or physician appointment urgently, ideally within a few days. The priority is to identify and control the hyperthyroidism, not to give hormones merely to increase menstrual flow.
  2. Do a urine or blood pregnancy test now if sexually active, even if the cycle date is normal, because a light period can occur in pregnancy and treatment choices differ in pregnancy.
  3. Confirm and find the cause with:
    • Free T4 and free T3
    • TSH repeated, preferably at a reliable lab
    • TRAb/TSI antibodies for Graves' disease
    • CBC and liver-function tests before starting an antithyroid drug
    • Thyroid examination and often ultrasound with Doppler
    • Thyroid uptake scan may be used when appropriate, but not in pregnancy or breastfeeding.
  4. Review supplements and medicines. Stop biotin hair/nail supplements for at least 2 to 3 days before repeat thyroid tests, unless the treating clinician advises otherwise. Biotin can interfere with some thyroid assays.
  5. Treatment must be prescribed after assessment of the cause. Doctors commonly use:
    • A beta-blocker for troublesome fast pulse, tremor, or anxiety
    • An antithyroid medicine such as methimazole/carbimazole, or PTU in specific situations including early pregnancy
    • Longer-term options, depending on the diagnosis: antithyroid drugs, radioactive iodine, or surgery.
      Do not start carbimazole/methimazole, PTU, propranolol, or menstrual hormone tablets without a clinician's assessment.
Once thyroid hormone levels return toward normal, menstrual amount and fertility often improve.

Seek emergency care today if any of these are present

  • Resting pulse persistently over 120/min, chest pain, breathlessness, fainting, or irregular heartbeat
  • High fever, severe agitation/confusion, repeated vomiting/diarrhea
  • Severe weakness or dehydration
  • Eye pain, loss of vision, or marked swelling around the eyes
  • Pregnancy with these abnormal thyroid results
Also, if antithyroid treatment is started, urgent review is required for fever, sore throat, mouth ulcers, jaundice, or dark urine, because these can rarely signal serious drug reactions.
Do not treat the scanty menses in isolation. The abnormal thyroid results are significant and are the likely explanation, but pregnancy and other gynecologic causes should still be excluded.

Can HbsAg can become non reactive when treated for 2 years on antiviral ??

Reading File
I’ll check what HBsAg loss means during chronic hepatitis B antiviral treatment and how it should be confirmed.
Finding Sources
Finding Sources
Searching PubMed

chronic hepatitis B HBsAg loss nucleos(t)ide analogues

Searching the Web

AASLD chronic hepatitis B HBsAg loss antiviral therapy monitoring

Yes. HBsAg can become non-reactive during antiviral treatment, but with oral antivirals such as tenofovir or entecavir, this is uncommon within only 2 years. Most patients achieve undetectable HBV DNA first, while HBsAg remains positive for years.
HBsAg becoming negative is called HBsAg loss/seroclearance. It is the best available marker of a “functional cure,” but it does not always mean every trace of HBV has been eliminated. Yamada’s Textbook of Gastroenterology defines serologic response as HBsAg seroclearance, with or without anti-HBs development.

If HBsAg is now non-reactive, confirm it

Ask the hepatologist to repeat or obtain:
  • HBsAg, preferably repeat in a reliable laboratory
  • Anti-HBs antibody
  • Total anti-HBc antibody
  • Quantitative HBV DNA PCR
  • ALT, AST, bilirubin, albumin, INR, platelet count
  • HBeAg and anti-HBe, if previously relevant
  • Liver fibrosis assessment, for example FibroScan, if not already done
A reassuring pattern after HBsAg loss is:
TestExpected result
HBsAgNegative / non-reactive
HBV DNA PCRUndetectable
Anti-HBsMay become positive, but not always immediately
ALT/ASTNormal

Important: do not stop the antiviral on your own

Whether treatment can be stopped depends on:
  • The antiviral being used
  • Whether the person has cirrhosis or advanced fibrosis
  • HBV DNA and ALT history
  • HBeAg status
  • Coinfection with HIV, hepatitis C, or hepatitis D
  • Pregnancy plans and immune-suppressing medicines
People with cirrhosis usually need particularly cautious, specialist-led decisions and ongoing liver cancer surveillance even after HBsAg clearance. Current AASLD guidance describes viral suppression and, when achievable, HBsAg loss as treatment goals, while still emphasizing follow-up after clearance (AASLD update).

Bottom line

  • Possible? Yes.
  • After 2 years of tenofovir/entecavir? Possible but not common.
  • Does non-reactive HBsAg mean treatment must stop? No. Confirm with repeat HBsAg, HBV DNA PCR, anti-HBs, and a hepatologist's review before changing any medicine.
This is a shared conversation. Sign in to Orris to start your own chat.