Here is a comprehensive guide to 10 common heart diseases with their ECG changes and representative ECG images.
10 Common Heart Diseases: ECG Changes & Images
1. π« ST-Elevation Myocardial Infarction (STEMI)
ECG Changes
- Hyperacute T waves (earliest sign β tall, peaked, broad-based)
- ST-segment elevation β₯1 mm in β₯2 contiguous limb leads or β₯2 mm in precordial leads (convex/tombstone morphology)
- Reciprocal ST depression in opposite leads
- Pathological Q waves develop within hours (necrosis marker)
- T-wave inversion in evolving phase
Localization by Leads
| Territory | Leads with ST elevation | Artery |
|---|
| Anterior | V1βV4 | LAD |
| Inferior | II, III, aVF | RCA |
| Lateral | I, aVL, V5βV6 | LCx/LAD |
| Posterior | Reciprocal depression V1βV3 | RCA/LCx |
ECG Image β Anterior STEMI (LAD occlusion)
Classic tombstone ST elevation in V2βV5 with evolving QS waves, consistent with proximal LAD occlusion.
2. β€οΈ Atrial Fibrillation (AF)
ECG Changes
- Absent P waves β replaced by chaotic fibrillatory (f) waves, best seen in V1 and lead II
- Irregularly irregular RR intervals (hallmark)
- Narrow QRS complexes (unless aberrant conduction or pre-excitation)
- Rate: can be slow (<60 bpm), controlled (60β100 bpm), or rapid (>100 bpm = AF with rapid ventricular response)
- f-wave frequency: 350β600 impulses/min
ECG Image β Atrial Fibrillation with rapid ventricular response
Absent P waves replaced by fibrillatory baseline, irregularly irregular RR intervals at ~126 bpm.
3. π΄ Complete (Third-Degree) Heart Block
ECG Changes
- Complete AV dissociation β P waves and QRS complexes march independently
- Atrial rate > ventricular rate
- Regular PP intervals and regular RR intervals, but no fixed PR relationship
- Escape rhythm:
- Junctional (narrow QRS, rate 40β60 bpm) β block at AV node
- Ventricular (wide QRS >120ms, rate 20β40 bpm) β block below His bundle
- P waves may be buried in QRS or T waves
ECG Image β Third-Degree (Complete) AV Block
P waves and QRS complexes are completely dissociated. Wide QRS ventricular escape at ~35 bpm.
4. π Acute Pericarditis
ECG Changes (4 stages)
- Stage 1 (acute): Diffuse concave/saddle-shaped ST elevation in most leads (except aVR & V1); PR-segment depression (most specific sign); Spodick's sign (downsloping TP segment)
- Stage 2: ST normalizes; PR depression persists
- Stage 3: Diffuse T-wave inversions
- Stage 4: Return to normal
Key differentiator from STEMI: ST elevation is diffuse (not territory-limited), concave (not convex), and PR depression is present
ECG Image β Acute Pericarditis
Diffuse saddle-shaped ST elevation across most leads, PR-segment depression in II, III, aVF, V4βV6, and reciprocal changes in aVR.
5. π« Pulmonary Embolism (PE)
ECG Changes
- Sinus tachycardia (most common β seen in ~40% of cases)
- S1Q3T3 pattern (classic but only ~20% sensitive):
- Prominent S wave in lead I
- Q wave in lead III
- Inverted T wave in lead III
- Right axis deviation
- Right bundle branch block (complete or incomplete)
- T-wave inversions in V1βV4 (right ventricular strain)
- P pulmonale (peaked P waves β right atrial overload)
- New AF may occur
ECG Image β Pulmonary Embolism with S1Q3T3
Sinus tachycardia at ~116 bpm, S1Q3T3 pattern, incomplete RBBB, T-wave inversions V1βV3 β classic right heart strain from acute PE.
6. π Wolff-Parkinson-White (WPW) Syndrome
ECG Changes (sinus rhythm / pre-excitation pattern)
- Short PR interval (<120 ms) β early ventricular activation via accessory pathway
- Delta wave β slurred upstroke at start of QRS (partial pre-excitation)
- Wide QRS complex (>120 ms total)
- Discordant ST-T changes (secondary to abnormal depolarization)
- Pseudo Q waves in inferior leads (mimics inferior MI)
- SVT/AVRT during tachycardia: typically narrow complex (orthodromic); wide complex if antidromic or in AF
ECG Image β WPW Syndrome with delta waves
Short PR interval, slurred delta waves (arrows in II and III), wide QRS β classic WPW pre-excitation pattern with anteroseptal accessory pathway.
7. π Ventricular Tachycardia (VT)
ECG Changes
- Rate: 100β250 bpm
- Wide QRS complexes (>120 ms, often >140 ms)
- Regular rhythm (monomorphic VT) or irregular (polymorphic/TdP)
- AV dissociation (P waves independent of QRS β pathognomonic when visible)
- Fusion beats and capture beats (confirm VT)
- Concordance: all precordial leads positive or all negative β ventricular origin
- Axis: extreme right axis deviation ("northwest axis") common
Brugada criteria distinguish VT from SVT-with-aberrancy
ECG Image β Monomorphic Ventricular Tachycardia
Rapid wide-complex tachycardia with positive precordial concordance and superior axis, consistent with monomorphic VT from structural heart disease.
8. π‘ Left Ventricular Hypertrophy (LVH)
ECG Changes
- Voltage criteria (most specific: Cornell, Sokolow-Lyon):
- Sokolow-Lyon: S in V1 + R in V5 or V6 β₯35 mm
- Cornell: R in aVL + S in V3 >28 mm (men), >20 mm (women)
- R in aVL β₯12 mm alone
- LV strain pattern: ST depression + asymmetric T-wave inversion in lateral leads (I, aVL, V5βV6)
- Left axis deviation
- Prolonged QRS duration
- Left atrial enlargement (P mitrale: broad notched P in II, deep biphasic P in V1)
ECG Image β LVH with Strain Pattern
High Cornell voltage with prominent T-wave inversions in V4βV6 and I, aVL β classic LVH with lateral strain pattern.
9. π΅ Hypertrophic Cardiomyopathy (HCM)
ECG Changes
- LVH voltage criteria (high amplitude QRS in precordial leads)
- Giant deep T-wave inversions in precordial leads (especially V2βV5) β most striking in apical HCM (Yamaguchi syndrome), can reach >10 mm
- Abnormal Q waves in lateral and inferior leads (septal hypertrophy)
- Left axis deviation
- ST-segment depression in lateral leads
- AF β common complication (~20% of patients)
- P-wave abnormalities (left atrial enlargement)
- High risk for sudden death β arrhythmias may be first presentation
ECG Image β Apical HCM with Giant T-wave Inversions
High-voltage QRS with deep symmetric T-wave inversions V2βV5, characteristic of apical hypertrophic cardiomyopathy (Yamaguchi syndrome).
10. π€ Dilated Cardiomyopathy (DCM)
ECG Changes
- Left bundle branch block (LBBB) β most common pattern:
- Wide QRS β₯120 ms
- Broad monophasic R in I, aVL, V5βV6
- rS or QS in V1βV3
- Discordant ST-T changes
- Poor R-wave progression (V1βV4 β reflecting anterior wall thinning/fibrosis)
- Non-specific intraventricular conduction delay (IVCD)
- Atrial fibrillation (common due to atrial dilation)
- Pathological Q waves (mimicking prior MI β due to fibrosis)
- PVCs and non-sustained VT (common, β SCD risk)
- Low voltage (if large pericardial effusion co-exists)
ECG Image β DCM with LBBB
Wide QRS with deep S waves in V1βV3 and broad monophasic R waves in lateral leads β classic LBBB pattern seen in dilated cardiomyopathy.
Quick Reference Summary Table
| # | Disease | Key ECG Hallmarks |
|---|
| 1 | STEMI | ST elevation (convex) in territory, reciprocal depression, Q waves |
| 2 | Atrial Fibrillation | Absent P waves, irregularly irregular RR, fibrillatory baseline |
| 3 | Complete Heart Block | AV dissociation, P and QRS march independently, escape rhythm |
| 4 | Acute Pericarditis | Diffuse saddle-shaped ST elevation, PR depression, Spodick's sign |
| 5 | Pulmonary Embolism | Sinus tachycardia, S1Q3T3, RBBB, T inversions V1βV4 |
| 6 | WPW Syndrome | Short PR, delta wave, wide QRS, secondary ST-T changes |
| 7 | Ventricular Tachycardia | Wide complex tachycardia, AV dissociation, fusion beats, concordance |
| 8 | LVH | Sokolow-Lyon/Cornell voltage, lateral strain (ST depression + T inversion) |
| 9 | HCM | Giant T-wave inversions (V2βV5), LVH voltage, abnormal Q waves |
| 10 | DCM | LBBB, poor R-wave progression, AF, PVCs, pathological Q waves |
Sources: Braunwald's Heart Disease (9780323722193), Goldman-Cecil Medicine (9780323930345), Rosen's Emergency Medicine (9780323757898)